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  1. Article ; Online: Black rice anthocyanins nanoparticles based on bovine serum albumin and hyaluronic acid: Preparation, characterization, absorption and intestinal barrier function protection in Caco-2 monolayers.

    Zhang, Mingxin / Zhou, Na / Zhao, Lei / Zhao, Liang

    International journal of biological macromolecules

    2024  Volume 267, Issue Pt 2, Page(s) 131325

    Abstract: Black rice anthocyanins (BRA) nanoparticles (NPs) were prepared using hyaluronic acid (HA), oxidized hyaluronic acid (OHA) and bovine serum albumin (BSA) to enhance the absorption and bioactivity of anthocyanins (ACNs). Results showed that HA/OHA-BSA-BRA ...

    Abstract Black rice anthocyanins (BRA) nanoparticles (NPs) were prepared using hyaluronic acid (HA), oxidized hyaluronic acid (OHA) and bovine serum albumin (BSA) to enhance the absorption and bioactivity of anthocyanins (ACNs). Results showed that HA/OHA-BSA-BRA NPs had a spherical morphology and excellent dispensability, with hydrated radius ~ 500 nm, zeta potential ~ - 30 mV, and encapsulation efficiency ~21 %. Moreover, using in vitro gastrointestinal release assay, we demonstrated that both BRA-loaded NPs exhibited effective controlled release properties of ACNs, significantly enhancing the accessibility of ACNs to the intestine. Cellular experiments showed that both two NPs had good biocompatibility and increased uptake of BRA. Furthermore, in comparison to the free BRA group, both BRA NPs groups significantly decreased the TEER value and increased the expression of tight junction proteins (Claudin 1, Occludin and ZO-1) in Caco-2 cell monolayers with LPS-induced damage. Therefore, our study demonstrated that HA/OHA-BSA-BRA NPs are promising carriers of ACNs and can effectively prevent the LPS-induced intestinal barrier injury in vitro.
    MeSH term(s) Humans ; Anthocyanins/pharmacology ; Anthocyanins/chemistry ; Hyaluronic Acid/chemistry ; Hyaluronic Acid/pharmacology ; Nanoparticles/chemistry ; Caco-2 Cells ; Serum Albumin, Bovine/chemistry ; Oryza/chemistry ; Animals ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/drug effects ; Cattle ; Drug Carriers/chemistry ; Intestinal Barrier Function
    Chemical Substances Anthocyanins ; Hyaluronic Acid (9004-61-9) ; Serum Albumin, Bovine (27432CM55Q) ; Drug Carriers
    Language English
    Publishing date 2024-04-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.131325
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2374: Show issues Location:
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  2. Article ; Online: Retrospective Analysis of Structure-Property Relationship of Emergent Metallo-Supramolecular Polymer Networks.

    Chang, Wei / Song, Weihua / Zhang, Mingxin / Yin, Panchao

    ChemPlusChem

    2024  , Page(s) e202400270

    Abstract: Metallo-supramolecular polymer networks (MSPNs) are fabricated from the crosslinking of polymers by discrete supramolecular coordination complexes. Due to the availability of various coordination complexes, e.g., 2D macrocycles and 3D nanocages, the ... ...

    Abstract Metallo-supramolecular polymer networks (MSPNs) are fabricated from the crosslinking of polymers by discrete supramolecular coordination complexes. Due to the availability of various coordination complexes, e.g., 2D macrocycles and 3D nanocages, the MSPNs have been recently developed with broadly tuned visco-elasticity and enriched functions inherited from the coordination complexes. The coordination complexes possess enriched topologies and unique structural relaxation dynamics, rendering them the capability to break the traditional tradeoffs of polymer systems for the design of materials with enhanced mechanical performance. The structure-property relationship studies are critical for the material-by-design of MSPNs, while the spatiotemporal investigations are desired for the exploration of dynamics information. The work summarizes recent studies on the unique ligand-exchange kinetics and the multi-level structural relaxation dynamics of MSPNs. The MSPNs' mechanical properties can be quantitatively correlated with the dynamics for understanding the structure-property relationship. This concept will not only serve to attract more researchers to engage in the study of the structure-activity relationship of MSPNs but also inspire innovative research findings pertaining to the application of MSPNs.
    Language English
    Publishing date 2024-05-16
    Publishing country Germany
    Document type Journal Article
    ISSN 2192-6506
    ISSN (online) 2192-6506
    DOI 10.1002/cplu.202400270
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  3. Article: Modeling the influence of basketball players' offense roles on team performance.

    Chen, Ruobing / Zhang, Mingxin / Xu, Xiao

    Frontiers in psychology

    2023  Volume 14, Page(s) 1256796

    Abstract: This study aimed to (1) use the clustering method to build a classification model based on the play-type data of basketball players, to classify native and foreign players into different offensive roles; (2) use the clustered offensive role model to ... ...

    Abstract This study aimed to (1) use the clustering method to build a classification model based on the play-type data of basketball players, to classify native and foreign players into different offensive roles; (2) use the clustered offensive role model to investigate how different offensive roles influence team performance. The sample was drawn from 20 teams spanning five seasons (2017-2021) in the Chinese Basketball Association, comprising 823 native and 228 foreign players. The clustering results obtained fourteen offensive roles for native players and five for foreign players. Subsequent analyses revealed that the offensive roles of two native player clusters, namely N6 Spot-up Wings who Attack (OR = 3.281,
    Language English
    Publishing date 2023-09-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1256796
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  4. Article ; Online: Black Phosphorus for Photonic Integrated Circuits.

    Zhang, Mingxin / Yang, Lele / Wu, Xiaoxuan / Wang, Junjia

    Research (Washington, D.C.)

    2023  Volume 6, Page(s) 206

    Abstract: Black phosphorus gives several advantages and complementarities over other two-dimensional materials. It has drawn extensive interest owing to its relatively high carrier mobility, wide tunable bandgap, and in-plane anisotropy in recent years. This ... ...

    Abstract Black phosphorus gives several advantages and complementarities over other two-dimensional materials. It has drawn extensive interest owing to its relatively high carrier mobility, wide tunable bandgap, and in-plane anisotropy in recent years. This manuscript briefly reviews the structure and physical properties of black phosphorus and targets on black phosphorus for photonic integrated circuits. Some of the applications are discussed including photodetection, optical modulation, light emission, and polarization conversion. Corresponding recent progresses, associated challenges, and future potentials are covered.
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2639-5274
    ISSN (online) 2639-5274
    DOI 10.34133/research.0206
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  5. Article ; Online: Ultrasound Sonosensitizers for Tumor Sonodynamic Therapy and Imaging: A New Direction with Clinical Translation.

    Liang, Yunlong / Zhang, Mingzhen / Zhang, Yujie / Zhang, Mingxin

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 18

    Abstract: With the rapid development of sonodynamic therapy (SDT), sonosensitizers have evolved from traditional treatments to comprehensive diagnostics and therapies. Sonosensitizers play a crucial role in the integration of ultrasound imaging (USI), X-ray ... ...

    Abstract With the rapid development of sonodynamic therapy (SDT), sonosensitizers have evolved from traditional treatments to comprehensive diagnostics and therapies. Sonosensitizers play a crucial role in the integration of ultrasound imaging (USI), X-ray computed tomography (CT), and magnetic resonance imaging (MRI) diagnostics while also playing a therapeutic role. This review was based on recent articles on multifunctional sonosensitizers that were used in SDT for the treatment of cancer and have the potential for clinical USI, CT, and MRI applications. Next, some of the shortcomings of the clinical examination and the results of sonosensitizers in animal imaging were described. Finally, this paper attempted to inform the future development of sonosensitizers in the field of integrative diagnostics and therapeutics and to point out current problems and prospects for their application.
    MeSH term(s) Animals ; Ultrasonography ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-09-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28186484
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    Zs.MO 81: Show issues

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  6. Article ; Online: Effects of school indoor visual environment on children's health outcomes: A systematic review.

    Meng, Xue / Zhang, Mingxin / Wang, Mohan

    Health & place

    2023  Volume 83, Page(s) 103021

    Abstract: Children's visual perceptions are critical for their comfort and health. This review explores the impacts of school indoor visual environment on children's health outcomes. A systematic search yielded 5704 articles, of which 32 studies were reviewed. ... ...

    Abstract Children's visual perceptions are critical for their comfort and health. This review explores the impacts of school indoor visual environment on children's health outcomes. A systematic search yielded 5704 articles, of which 32 studies were reviewed. Five environmental themes were identified: lighting, access to nature, window characteristics, art/environmental aesthetics, and ergonomics/spatial arrangement. Results affirm that visual environment affects children's health. There are disparities across environmental themes, with more extensive evidence for lighting and access to nature, but relatively limited in other areas. This study suggests a need for multi-disciplinary collaboration to develop a holistic perspective.
    MeSH term(s) Child ; Humans ; Child Health ; Schools ; Air Pollution, Indoor
    Language English
    Publishing date 2023-07-02
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1262540-1
    ISSN 1873-2054 ; 1353-8292
    ISSN (online) 1873-2054
    ISSN 1353-8292
    DOI 10.1016/j.healthplace.2023.103021
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4333: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Role of epigenetic modifications mediated by vitamins and trace elements in inflammatory bowel disease.

    Liu, Hao / Lu, Ning / Cui, Manli / Zhang, Mingxin

    Epigenomics

    2023  Volume 15, Issue 17, Page(s) 839–843

    Abstract: Graphical abstract [Formula: see text] Numerous environmental factors frequently emerge as primary determinants of inflammatory bowel disease (IBD). Diet is a major component of environmental factors, and the consumption of vitamins (A, B, C and D) and ... ...

    Abstract Graphical abstract [Formula: see text] Numerous environmental factors frequently emerge as primary determinants of inflammatory bowel disease (IBD). Diet is a major component of environmental factors, and the consumption of vitamins (A, B, C and D) and trace elements (calcium, iron, zinc and selenium) exerts an impact on the progression of IBD through epigenetic modifications. Intake of vitamins A, B, C and D, as well as excessive amounts of iron and calcium, can modulate the condition of IBD by regulating the levels of DNA methylation, histone acetylation and miRNA. Zinc and selenium alleviate the progression of IBD by regulating the levels of promoter methylation or histone ubiquitination, respectively. Graphical Abstract was adapted from 'Epigenetic levels (layout)', by BioRender.com. Retrieved from https://app.biorender.com/biorender-templates.
    MeSH term(s) Humans ; Trace Elements ; Vitamins/pharmacology ; Selenium ; Histones ; Calcium ; Inflammatory Bowel Diseases/genetics ; Vitamin A ; Zinc ; Iron ; Vitamin K ; Epigenesis, Genetic
    Chemical Substances Trace Elements ; Vitamins ; Selenium (H6241UJ22B) ; Histones ; Calcium (SY7Q814VUP) ; Vitamin A (11103-57-4) ; Zinc (J41CSQ7QDS) ; Iron (E1UOL152H7) ; Vitamin K (12001-79-5)
    Language English
    Publishing date 2023-09-11
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2537199-X
    ISSN 1750-192X ; 1750-1911
    ISSN (online) 1750-192X
    ISSN 1750-1911
    DOI 10.2217/epi-2023-0226
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  8. Article ; Online: Crystal Plane Engineering to Boost Water Cluster Evaporation for Enhanced Solar Steam Generation.

    Jia, Linhui / Liu, Zhongxin / Hao, Hongxun / Zhang, Mingxin / Tian, Xinlong / Huang, Wei

    Nano letters

    2024  Volume 24, Issue 5, Page(s) 1753–1760

    Abstract: Polymer based low evaporation enthalpy materials have become a universal selection for improving the efficiency of solar steam generation. Although water cluster and intermediate water mechanisms have been proposed to explain the low evaporation enthalpy, ...

    Abstract Polymer based low evaporation enthalpy materials have become a universal selection for improving the efficiency of solar steam generation. Although water cluster and intermediate water mechanisms have been proposed to explain the low evaporation enthalpy, the production process and microstructure of activated water are still unclear. Here, crystal plane engineering is used to investigate the intermediate water state and the water cluster activation mechanism. The unique open-closed coordination structure on the optimized crystal surface promotes the generation of firm water clusters by optimizing the intermediate water state. Under the similar solar energy absorption of all materials, crystal plane engineering increased the solar steam generation rate of the evaporator by 31.2% and increased the energy efficiency to 94.8%. Exploring the micro-evaporation process and activated water structure is expected to stimulate the development of the next generation low evaporation enthalpy materials.
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c04646
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  9. Article: Oral Administration of Platinum Nanoparticles with SOD/CAT Cascade Catalytic Activity to Alleviate Ulcerative Colitis.

    Liu, Hao / Zhang, Yujie / Zhang, Mingzhen / Yu, Zhaoxiang / Zhang, Mingxin

    Journal of functional biomaterials

    2023  Volume 14, Issue 11

    Abstract: Ulcerative colitis (UC) is a refractory chronic inflammatory disease involving the colon and rectum, falling under the category of inflammatory bowel disease (IBD). The accumulation of reactive oxygen species (ROS) in local tissues has been identified as ...

    Abstract Ulcerative colitis (UC) is a refractory chronic inflammatory disease involving the colon and rectum, falling under the category of inflammatory bowel disease (IBD). The accumulation of reactive oxygen species (ROS) in local tissues has been identified as a crucial contributor to the escalation of inflammatory responses. Therefore, eliminating ROS in the inflamed colon is a promising approach to treating UC. Nanomaterials with intrinsic enzyme-like activities (nanozymes) have shown significant therapeutic potential in UC. In this study, we found that platinum nanoparticles (Pt NPs) exhibited remarkable superoxide dismutase (SOD) and catalase (CAT) cascade catalytic activities, as well as effective hydroxyl radical (•OH) scavenging ability. The in vitro experiments showed that Pt NPs could eliminate excessive ROS to protect cells against oxidative stress. In the colitis model, oral administration of Pt NPs (loaded in chitosan/alginate hydrogel) could significantly alleviate UC, including reducing the colon length, the damaged epithelium, and the infiltration of inflammatory cells. Without appreciable systemic toxicity, Pt NPs represent a novel therapeutic approach to UC and are expected to achieve long-term inflammatory remission.
    Language English
    Publishing date 2023-11-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2648525-4
    ISSN 2079-4983
    ISSN 2079-4983
    DOI 10.3390/jfb14110548
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  10. Article: [The role of intestinal immune cells in regulation of fatty liver disease progress through gut-liver axis].

    Zhang, Ping / Zhang, Mingxin / Cheng, Shilin / Wang, Xin / Qin, Hongyan

    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

    2023  Volume 39, Issue 3, Page(s) 275–280

    Abstract: Fatty liver disease is one of the most prevalent chronic liver disease worldwide and the gut-liver axis is recognized as increasingly prominent in fatty liver disease. Intestinal dysfunction can affect the occurrence or progression of liver disease, ... ...

    Abstract Fatty liver disease is one of the most prevalent chronic liver disease worldwide and the gut-liver axis is recognized as increasingly prominent in fatty liver disease. Intestinal dysfunction can affect the occurrence or progression of liver disease, therein, validating the critical role of the intestinal immune cells. Enormous literature reported that macrophages, lymphocyte, dendritic cells (DCs) and other immune cells in the gut as well as their subsets may regulate the fatty liver disease progression via different mechanisms, including disruption of intestinal barrier, dysregulation of intestinal lipid transporters and mediating immune cell migration to liver.
    MeSH term(s) Humans ; Gastrointestinal Microbiome/physiology ; Liver ; Non-alcoholic Fatty Liver Disease
    Language Chinese
    Publishing date 2023-03-22
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1007-8738
    ISSN 1007-8738
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