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Article ; Online: Impact Analysis of Basketball Exercise Strength Based on Machine Learning in the Mental Health of College Students.

Zhang, Ran

Computational intelligence and neuroscience

2022 Volume 2022, Page(s) 9628446

Abstract: In the current environment of globalization, the communication between people is gradually getting closer, and the society is becoming more and more complex. With the continuous development and progress of science and technology, people are more skilled ... ...

Abstract	In the current environment of globalization, the communication between people is gradually getting closer, and the society is becoming more and more complex. With the continuous development and progress of science and technology, people are more skilled in applying science and technology to their own concerns. College students are about to enter the society, will feel multiple pressure from family, school, and society, study and life problems will gradually convert into mental health problems, and we need to use machine learning basketball exercise to positively affect the mental health quality of college students. The improvement of living conditions makes people pay more attention to their physical and mental health, and learn to use machine learning sports reasonably, not only basketball exercise, to improve mental health diseases. However, we need to use machine learning to identify the different effects of different basketball exercise intensity on mental health, in order to ensure that the most appropriate basketball exercise intensity brings good aspects to the mental health of college students. Through the investigation and data sampling, it can be concluded that the machine learning-based basketball exercise intensity has a positive impact on the mental health of college students.
MeSH term(s)	Basketball/psychology ; Exercise ; Humans ; Machine Learning ; Mental Health ; Students/psychology
Language	English
Publishing date	2022-09-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5273
ISSN (online)	1687-5273
ISSN	1687-5273
DOI	10.1155/2022/9628446
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Article ; Online: Deep Learning Unveils Hidden Angiography in Noncontrast CT Scans.

Zhang, Ran / Turkbey, Baris

Radiology

2023 Volume 309, Issue 2, Page(s) e232784

MeSH term(s)	Humans ; Deep Learning ; Angiography ; Tomography, X-Ray Computed
Language	English
Publishing date	2023-11-14
Publishing country	United States
Document type	Editorial
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.232784
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Article ; Online: On-Demand Centralized Resource Allocation for IoT Applications: AI-Enabled Benchmark.

Zhang, Ran / Liu, Lei / Dong, Mianxiong / Ota, Kaoru

Sensors (Basel, Switzerland)

2024 Volume 24, Issue 3

Abstract: The development of emerging information technologies, such as the Internet of Things (IoT), edge computing, and blockchain, has triggered a significant increase in IoT application services and data volume. Ensuring satisfactory service quality for ... ...

Abstract	The development of emerging information technologies, such as the Internet of Things (IoT), edge computing, and blockchain, has triggered a significant increase in IoT application services and data volume. Ensuring satisfactory service quality for diverse IoT application services based on limited network resources has become an urgent issue. Generalized processor sharing (GPS), functioning as a central resource scheduling mechanism guiding differentiated services, stands as a key technology for implementing on-demand resource allocation. The performance prediction of GPS is a crucial step that aims to capture the actual allocated resources using various queue metrics. Some methods (mainly analytical methods) have attempted to establish upper and lower bounds or approximate solutions. Recently, artificial intelligence (AI) methods, such as deep learning, have been designed to assess performance under self-similar traffic. However, the proposed methods in the literature have been developed for specific traffic scenarios with predefined constraints, thus limiting their real-world applicability. Furthermore, the absence of a benchmark in the literature leads to an unfair performance prediction comparison. To address the drawbacks in the literature, an AI-enabled performance benchmark with comprehensive traffic-oriented experiments showcasing the performance of existing methods is presented. Specifically, three types of methods are employed: traditional approximate analytical methods, traditional machine learning-based methods, and deep learning-based methods. Following that, various traffic flows with different settings are collected, and intricate experimental analyses at both the feature and method levels under different traffic conditions are conducted. Finally, insights from the experimental analysis that may be beneficial for the future performance prediction of GPS are derived.
Language	English
Publishing date	2024-02-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s24030980
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Article: Therapeutic Potential of Targeting the PERK Signaling Pathway in Ischemic Stroke.

Yu, Xinyuan / Dang, Lihong / Zhang, Ran / Yang, Wei

Pharmaceuticals (Basel, Switzerland)

2024 Volume 17, Issue 3

Abstract: Many pathologic states can lead to the accumulation of unfolded/misfolded proteins in cells. This causes endoplasmic reticulum (ER) stress and triggers the unfolded protein response (UPR), which encompasses three main adaptive branches. One of these UPR ... ...

Abstract	Many pathologic states can lead to the accumulation of unfolded/misfolded proteins in cells. This causes endoplasmic reticulum (ER) stress and triggers the unfolded protein response (UPR), which encompasses three main adaptive branches. One of these UPR branches is mediated by protein kinase RNA-like ER kinase (PERK), an ER stress sensor. The primary consequence of PERK activation is the suppression of global protein synthesis, which reduces ER workload and facilitates the recovery of ER function. Ischemic stroke induces ER stress and activates the UPR. Studies have demonstrated the involvement of the PERK pathway in stroke pathophysiology; however, its role in stroke outcomes requires further clarification. Importantly, considering mounting evidence that supports the therapeutic potential of the PERK pathway in aging-related cognitive decline and neurodegenerative diseases, this pathway may represent a promising therapeutic target in stroke. Therefore, in this review, our aim is to discuss the current understanding of PERK in ischemic stroke, and to summarize pharmacologic tools for translational stroke research that targets PERK and its associated pathways.
Language	English
Publishing date	2024-03-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2193542-7
ISSN	1424-8247
ISSN	1424-8247
DOI	10.3390/ph17030353
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Article ; Online: Radiographic grid for locating foreign bodies in maxillofacial emergency trauma.

Zhang, Ziqi / Yang, Mingliang / Zhang, Ran

BMC oral health

2024 Volume 24, Issue 1, Page(s) 46

Abstract: Objectives: The accurate localization of the foreign bodies (FBs) is essential. This work presents a new noninvasive technique for subcutaneous metallic FBs under a radiographic grid, a system that simplifies the localization of facial FBs removal using ...

Abstract	Objectives: The accurate localization of the foreign bodies (FBs) is essential. This work presents a new noninvasive technique for subcutaneous metallic FBs under a radiographic grid, a system that simplifies the localization of facial FBs removal using a grid with embedded reference points. Methods: This work designed a retrospective study to evaluate the effect of a radiographic grid on FBs removal surgery. All patients who met the inclusion criteria and attended the Hospital of Stomatology of China Medical University from January 2022 to June 2023 were enrolled and randomly divided into grid and non-grid groups. The assessment of facial swelling, the primary indicator, was conducted on days 2 and 7 post-surgery. The variables were analyzed using the Student t test and a repeated-measures general linear model. Results: The study sample consisted of 20 patients, with 14 males (70%) and 6 females (30%), who had an average age of 30.30 ± 5.38. The average time of operation was 1.85 ± 0.66 h (range 0.7 to 3.2). In the present cases in this report, of the 20 patients' FBs, 14 were metal, 5 were glass, and 1 was residual root. And the FBs were surgically removed with no postoperative complications. Through comparison, it was found that the degree of swelling on day 2 postoperatively was significantly different between the grid group and the non-grid group (P < 0.05). Conclusions: This study demonstrates that a radiographic grid with mark points is a more efficient approach compared with traditional methods for FBs removal, and this surgical method is more accurate, fast and noninvasive.
MeSH term(s)	Female ; Male ; Humans ; Young Adult ; Adult ; Retrospective Studies ; China ; Face ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/surgery ; Glass
Language	English
Publishing date	2024-01-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-023-03807-0
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Article ; Online: Sweet syndrome induced by FLT3 inhibitors: case report and literature review.

Yang, Linhui / Zhang, Ran / Ma, Hongbing

Hematology (Amsterdam, Netherlands)

2024 Volume 29, Issue 1, Page(s) 2337230

Abstract: Background: Acute febrile neutrophilic dermatosis, also commonly referred to as Sweet syndrome, is often associated with tumors, infections, immune disorders and medications. FLT3 inhibitor-induced Sweet syndrome is a rare complication.: Methods and ... ...

Abstract	Background: Acute febrile neutrophilic dermatosis, also commonly referred to as Sweet syndrome, is often associated with tumors, infections, immune disorders and medications. FLT3 inhibitor-induced Sweet syndrome is a rare complication. Methods and results: We report a patient with relapsed and refractory acute monocytic leukemia harboring high-frequency FLT3-ITD and DNMT3a mutations. The FLT3 inhibitor gilteritinib was administered for reinduction therapy after failure of chemotherapy with a combination of venetoclax, decitabine, aclarubicin, cytarabine and granulocyte colony-stimulating factor. The leukemia patient achieved remission after 1 month of treatment. However, Sweet syndrome induced by gilteritinib, which was confirmed by skin biopsy, developed during induction therapy. Similar cases of Sweet syndrome following FLT3 inhibitor therapy for acute myeloid leukemia were reviewed. Conclusion: Attention should be given to this rare complication when FLT3 inhibitors are used for acute myeloid leukemia therapy, and appropriate treatments need to be administered in a timely manner.
MeSH term(s)	Humans ; Sweet Syndrome/chemically induced ; Sweet Syndrome/diagnosis ; Aniline Compounds ; Pyrazines ; Leukemia, Myeloid, Acute/drug therapy ; fms-Like Tyrosine Kinase 3/genetics
Chemical Substances	gilteritinib (66D92MGC8M) ; Aniline Compounds ; Pyrazines ; FLT3 protein, human (EC 2.7.10.1) ; fms-Like Tyrosine Kinase 3 (EC 2.7.10.1)
Language	English
Publishing date	2024-04-02
Publishing country	England
Document type	Review ; Case Reports ; Journal Article
ZDB-ID	1341428-8
ISSN	1607-8454 ; 1024-5332 ; 1024-5340
ISSN (online)	1607-8454
ISSN	1024-5332 ; 1024-5340
DOI	10.1080/16078454.2024.2337230
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Article ; Online: Safety and effectiveness of opioid-free anaesthesia in thoracoscopic surgery: a preliminary retrospective cohort study.

Zhang, Shanshan / Zhang, Jianmin / Zhang, Ran

BMC anesthesiology

2024 Volume 24, Issue 1, Page(s) 60

Abstract: Background: This study aimed to observe the effect of opioid-free anaesthesia (OFA) on intraoperative haemodynamic,postoperative analgesia and postoperative nausea and vomiting (PONV) in thoracoscopic surgery in order to provide more evidence for ... ...

Abstract	Background: This study aimed to observe the effect of opioid-free anaesthesia (OFA) on intraoperative haemodynamic,postoperative analgesia and postoperative nausea and vomiting (PONV) in thoracoscopic surgery in order to provide more evidence for evaluating the safety and effectiveness of OFA technology. Methods: This was a single-centre retrospective observational study.Adult patients who underwent thoracoscopic surgery with the preoperative thoracic paravertebral block between January 2017 and June 2020 were included.A cohort of 101 thoracoscopic surgery patients who received the OFA technique were matched with 101 thoracoscopic surgery patients who received standard opioid-containing anaesthesia(SOA). Heart rate (HR) and mean arterial blood pressure (MAP) were measured before anaesthesia induction, immediately after endotracheal intubation, at the beginning of surgery, and 10, 20, and 30 min after surgery began.The total amount of intraoperative infusion, frequency of vasoactive drugs use, morphine ingested via the patient-controlled intravenous analgesia (PCIA) 24 h post-surgery,visual analogue scale (VAS) scores at rest and activity on the first day post-surgery, and frequency of nausea and vomiting within 24 h post-surgery were analysed. Results: There was no significant difference in intraoperative HR between the two groups (F = 0.889, P = 0.347); however, there was significant difference in intraoperative MAP (F = 16.709, P < 0.001), which was lower in SOA patients than in OFA patients. The frequency of vasoactive drug use and amount of infusion was less in OFA patients (P = 0.001). The consumption of morphine used by the PCIA 24 h post-surgery was significantly lower in OFA patients (OFA, 1.8 [0, 4.8] mg vs. SOA, 3.6 [0.6, 23] mg, P < 0.001). There was no significant difference in VAS scores at rest (P = 0.745) or during activity (P = 0.792) on the first day post-surgery. There was also no statistically significant difference in nausea and vomiting within 24 h post-surgery (P = 0.651). Conclusions: This case-control study demonstrated that compared with SOA, OFA can effectively maintain the stability of intraoperative MAP, reduce the incidence of hypotension. Although OFA reduced morphine consumption via the PCIA pump 24 h post-surgery, postoperative pain scores and nausea and vomiting within 24 h post-surgery were similar between the groups.But this study was only a preliminary study and needed to confirm in a larger, more robust trial.
MeSH term(s)	Adult ; Humans ; Analgesics, Opioid/therapeutic use ; Retrospective Studies ; Case-Control Studies ; Morphine/therapeutic use ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control ; Postoperative Nausea and Vomiting/epidemiology ; Postoperative Nausea and Vomiting/drug therapy ; Nerve Block/methods ; Thoracoscopy
Chemical Substances	Analgesics, Opioid ; Morphine (76I7G6D29C)
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2091252-3
ISSN	1471-2253 ; 1471-2253
ISSN (online)	1471-2253
ISSN	1471-2253
DOI	10.1186/s12871-024-02441-9
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Article: Effect of Humanistic Pain Management in Postpartum Women after Cesarean Delivery Based on Active Pain Assessment and Visual Analog Scale.

Peng, Yan / Li, Li / Wang, Kehui / Zhang, Ran

Alternative therapies in health and medicine

2024

Abstract: Objective: To explore the effect of humanistic pain management based on active pain assessment and the visual analog scale in postpartum women after cesarean delivery.: Methods: We selected 100 postpartum women who underwent cesarean delivery in ... ...

Abstract	Objective: To explore the effect of humanistic pain management based on active pain assessment and the visual analog scale in postpartum women after cesarean delivery. Methods: We selected 100 postpartum women who underwent cesarean delivery in Xuzhou Maternity and Child Health Care Hospital from April to December 2021 and divided the postpartum women into a management group and a conventional group, with 50 cases in each group. The conventional group was given routine pain management, while the management group was given humanistic pain management based on active pain assessment and visual analog scale score. The quality of pain management, sleep quality, unhealthy emotion, maternal comfort, breastfeeding rates, and patient compliance in the 2 groups were compared. Results: The most severe degree of pain, the least degree of pain, the frequency of moderate and severe pain, and the influence of pain on sleep were lower in the management group than in the conventional group. The Pittsburgh Sleep Quality Index score was lower and the Self-Rating Anxiety Scale and the Self-Rating Depression Scale scores were higher in the management group than in the conventional group. In addition, the comfort scores for the second day and the third day after delivery were higher in the management group than in the conventional group. The breastfeeding rate and patient compliance were higher in the management group than in the conventional group. Conclusion: Humanistic pain management based on active pain assessment and the visual analog scale can improve the quality of maternal pain management, the quality of sleep, and maternal comfort, ameliorate maternal adverse emotions, and promote breastfeeding and patient compliance.
Language	English
Publishing date	2024-03-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	1225073-9
ISSN	1078-6791
ISSN	1078-6791
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Article ; Online: Right Coronary Artery Occlusion Due to Foreign Body From Left Chest Traumatic Injury.

Zhang, Ran / Chen, Zhongxiu / Li, Chen

JACC. Cardiovascular interventions

2024 Volume 17, Issue 7, Page(s) 940–941

MeSH term(s)	Humans ; Coronary Vessels/diagnostic imaging ; Treatment Outcome ; Coronary Occlusion/diagnostic imaging ; Coronary Occlusion/etiology ; Coronary Occlusion/therapy ; Coronary Disease ; Foreign Bodies/complications ; Foreign Bodies/diagnostic imaging ; Coronary Angiography
Language	English
Publishing date	2024-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2024.01.303
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Article ; Online: Cancer-associated fibroblast-derived gene signatures predict radiotherapeutic survival in prostate cancer patients.

Zhang, Ran / Liu, Feng

Journal of translational medicine

2022 Volume 20, Issue 1, Page(s) 453

Abstract: Background: Cancer-associated fibroblasts (CAFs) play multiple roles in regulating tumor metastasis and treatment response. Current clinical indicators are insufficient to accurately assess disease risk and radiotherapy response, emphasizing the urgent ... ...

Abstract	Background: Cancer-associated fibroblasts (CAFs) play multiple roles in regulating tumor metastasis and treatment response. Current clinical indicators are insufficient to accurately assess disease risk and radiotherapy response, emphasizing the urgent need for additional molecular prognostic markers. Methods: In order to investigate CAF-related genes associated with radiotherapy and construct prognostic CAF-related gene signatures for prostate cancer, we firstly established a radio-resistant prostate CAF cell subline (referred to as CAFR) from Mus-CAF (referred to as CAF) through fractionated irradiation using X-rays. Transcriptome sequencing for CAF and CAFR was conducted, and 2626 CAF-related differentially expressed genes (DEGs) associated with radiotherapy were identified. Human homologous genes of mouse CAF-related DEGs were then obtained. Results: Functional enrichment analysis revealed that these CAF-related DEGs were significantly enriched ECM- and immune-related functions and pathways. Based on GSE116918 dataset, 186 CAF-related DEGs were correlated with biochemical recurrence-free survival (BCRFS) of prostate cancer patients, 16 of which were selected to construct a BCRFS-related CAF signature, such as ACPP, THBS2, and KCTD14; 142 CAF-related DEGs were correlated with metastasis-free survival (MFS), 16 of which were used to construct a MFS-related CAF signature, such as HOPX, TMEM132A, and ZNF467. Both Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) datasets confirmed that the two CAF signatures accurately predicted BCRFS and MFS of prostate cancer patients. The risk scores were higher in patients with higher gleason grades and higher clinical T stages. Moreover, the BCRFS-related CAF signature was an independent prognostic factor and a nomogram consisting of BCRFS-related CAF signature and various clinical factors accurately predicted 2-, 3-, and 5-year survival time of prostate cancer patients. Furthermore, the risk score was positively correlated with multiple immune checkpoints. Conclusions: Our established CAF signatures could accurately predict BCRFS and MFS in prostate cancer patients undergoing radiotherapy.
MeSH term(s)	Animals ; Biomarkers/metabolism ; Cancer-Associated Fibroblasts/metabolism ; Cancer-Associated Fibroblasts/pathology ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Mice ; Prognosis ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/radiotherapy
Chemical Substances	Biomarkers
Language	English
Publishing date	2022-10-04
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2118570-0
ISSN	1479-5876 ; 1479-5876
ISSN (online)	1479-5876
ISSN	1479-5876
DOI	10.1186/s12967-022-03656-5
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