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  1. Article ; Online: Advances in the Diagnosis and Treatment of Rare Cardiovascular Diseases

    ZHANG Shuyang / TIAN Zhuang / ZHANG Shuyuan / WANG Zeyuan

    罕见病研究, Vol 2, Iss 1, Pp 1-

    2023  Volume 5

    Abstract: The onset of rare cardiovascular diseases is early and the mortality is high. The patients of the disease face a long time of hardship in diagnosis and a low treatment rate. As a result, it is urgent to improve the diagnosis and treatment level of rare ... ...

    Abstract The onset of rare cardiovascular diseases is early and the mortality is high. The patients of the disease face a long time of hardship in diagnosis and a low treatment rate. As a result, it is urgent to improve the diagnosis and treatment level of rare diseases and to accelerate the selection and R&D of drugs of rare cardiovascular diseases. In recent years, with the rapid development of new technology and basic research, the diagnosis and treatment of rare cardiovascular diseases have made breakthroughs. The article summarizes the research progress in diagnosis and treatment of rare cardiovascular diseases and looks into the future of the research.
    Keywords rare diseases ; cardiovascular diseases ; diagnosis ; treatment ; Medicine ; R
    Language Chinese
    Publishing date 2023-01-01T00:00:00Z
    Publisher Editorial Office of Journal of Rare Diseases
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: High selective removal towards Hg(II) from aqueous solution with magnetic diatomite-based adsorbent functionalized by poly(3-aminothiophenol): conditional optimization, application, and mechanism.

    Zhang, Shuyuan / Qian, Lin / Zhou, Yu / Guo, Yongfu

    Environmental science and pollution research international

    2023  Volume 30, Issue 19, Page(s) 56121–56136

    Abstract: A novel diatomite-based (DMT) material was obtained by post-functionalization of DMT/ ... ...

    Abstract A novel diatomite-based (DMT) material was obtained by post-functionalization of DMT/CoFe
    MeSH term(s) Mercury ; Adsorption ; Magnetic Phenomena ; Ions ; Adenosine Triphosphate ; Kinetics ; Hydrogen-Ion Concentration
    Chemical Substances diatomite (68855-54-9) ; Mercury (FXS1BY2PGL) ; Ions ; Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2023-03-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-26070-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A new trapdoor spider of

    Yu, Kun / Li, Changze / Zhang, Shuyuan / Zhang, Feng

    Biodiversity data journal

    2023  Volume 11, Page(s) e98311

    Abstract: Background: The genus : New information: A new species, ...

    Abstract Background: The genus
    New information: A new species,
    Language English
    Publishing date 2023-04-07
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2736709-5
    ISSN 1314-2828
    ISSN 1314-2828
    DOI 10.3897/BDJ.11.e98311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: PD-L1 inhibitor plus gemcitabine and cisplatin therapy followed by conversion surgery for initially unresectable advanced gallbladder cancer.

    Zhang, Shuyuan / Nie, Jianhua / Tai, Sheng / Zheng, Tongsen

    BMJ case reports

    2023  Volume 16, Issue 12

    Abstract: Advanced gallbladder cancer (GBC) is not amenable to surgical resection. There are limited treatment options and the prognosis is dismal. The role of immune checkpoint inhibitors in conversion therapy remains unclear for initially unresectable advanced ... ...

    Abstract Advanced gallbladder cancer (GBC) is not amenable to surgical resection. There are limited treatment options and the prognosis is dismal. The role of immune checkpoint inhibitors in conversion therapy remains unclear for initially unresectable advanced GBC. We present a case of a woman in her late 60s diagnosed with stage IV GBC with liver and para-aortic and retroperitoneal lymph node metastases, who achieved a pathological complete response after three cycles of programmed cell death-ligand 1 inhibitor durvalumab combined with gemcitabine and cisplatin regimen and underwent conversion surgery without complication. The patient went on to develop disease progression without adjuvant therapy 6 months after surgery.
    MeSH term(s) Female ; Humans ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cisplatin/therapeutic use ; Gallbladder Neoplasms/drug therapy ; Gallbladder Neoplasms/surgery ; Gallbladder Neoplasms/pathology ; Gemcitabine ; Immune Checkpoint Inhibitors/therapeutic use ; Aged
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Gemcitabine ; Immune Checkpoint Inhibitors
    Language English
    Publishing date 2023-12-20
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-255403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A new trapdoor spider of Cyclocosmia Ausserer, 1871 from southern China (Araneae, Halonoproctidae)

    Yu, Kun / Li, Changze / Zhang, Shuyuan / Zhang, Feng

    Biodiversity Data Journal. 2023 Apr. 07, v. 11 p.e98311-

    2023  

    Abstract: The genus Cyclocosmia Ausserer, 1871 previously included ten species from North America and Asia, six of which have been recorded from China. A new species, Cyclocosmiaruyi Yu & Zhang sp. n., is described and diagnosed, based on both sexes from Guangxi ... ...

    Abstract The genus Cyclocosmia Ausserer, 1871 previously included ten species from North America and Asia, six of which have been recorded from China. A new species, Cyclocosmiaruyi Yu & Zhang sp. n., is described and diagnosed, based on both sexes from Guangxi Province, China. Morphological characters for the early stages of juveniles of the new species are also provided.
    Keywords Araneae ; biodiversity ; new species ; spiders ; China ; North America ; Opisthosomal disc ; early stages of spiderling ; morphology ; taxonomy ; variation
    Language English
    Dates of publication 2023-0407
    Publishing place Pensoft Publishers
    Document type Article ; Online
    ZDB-ID 2736709-5
    ISSN 1314-2828
    ISSN 1314-2828
    DOI 10.3897/BDJ.11.e98311
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Two new species of the genus

    Zhang, Shu-Yuan / Wang, Cheng-Bin

    Biodiversity data journal

    2021  Volume 9, Page(s) e72456

    Abstract: Background: The genus : New information: Two new species of mygalomorph spiders, ...

    Abstract Background: The genus
    New information: Two new species of mygalomorph spiders,
    Language English
    Publishing date 2021-12-07
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2736709-5
    ISSN 1314-2828
    ISSN 1314-2828
    DOI 10.3897/BDJ.9.e72456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Association Between Oral Behaviors and Painful Temporomandibular Disorders: A Cross-Sectional Study in the General Population.

    Sun, Ruonan / Zhang, Shuyuan / Si, Jiarui / Zhang, Liming / Yang, Haolun / Ye, Zheng / Xiong, Xin

    Journal of pain research

    2024  Volume 17, Page(s) 431–439

    Abstract: Background: Studies have reported correlations between various oral behaviors and painful temporomandibular disorders (TMD), yet comprehensive research on the independent effects of each oral behavior within the general population remains sparse.: ... ...

    Abstract Background: Studies have reported correlations between various oral behaviors and painful temporomandibular disorders (TMD), yet comprehensive research on the independent effects of each oral behavior within the general population remains sparse.
    Objective: This cross-sectional study aimed to investigate the association between painful TMD (PT) and various oral behaviors in general population.
    Methods: A questionnaire survey was conducted with participants to collect data encompassing demographic characteristics, eight specific oral behaviors, and the 5 major TMD symptoms(5Ts) checklist. Participants were categorized into PT and non-PT (NPT) groups based on their responses to the 5Ts checklist. Those reporting TMJ/facial pain or headaches were assigned to the PT group, while all other participants constituted the NPT group. Both univariate and multivariate logistic regression analyses were employed to evaluate the association between individual oral behavior and the presence of PT, controlling for demographic confounders including age, sex, systemic diseases, and dental treatments history.
    Results: A total of 441 valid questionnaires were received, including 156 males and 285 females. The prevalence of PT was identified to be 33.33%, with 61.00% of participants engaging in one or more types of oral behaviors. Each oral behavior was more frequently reported in the PT group compared to the NPT group. The univariate logistic regression analysis identified positive correlations between all eight oral behaviors and PT. In the multivariate logistic regression analysis, these associations persisted after adjustment for demographic confounders including age, sex, history of systemic diseases and dental treatments (P<0.01). The behaviors most strongly associated with PT were "Hold or jut jaw forward/to the side" (OR:4.478), "Hold, tighten or tense muscles without clench" (OR:3.343) and "Hold jaw in rigid or tense position" (OR:3.209).
    Conclusion: The presence of oral behaviors has significant association with PT. Individuals exhibiting multiple oral behaviors are more likely to experience PT. Additional studies are needed to clarify the effects of reducing oral behaviors on pain-related symptoms.
    Language English
    Publishing date 2024-02-01
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2495284-9
    ISSN 1178-7090
    ISSN 1178-7090
    DOI 10.2147/JPR.S449377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The G1/S transition in mammalian stem cells

    Xie, Shicong / Zhang, Shuyuan / de Medeiros, Gustavo / Liberali, Prisca / Skotheim, Jan M

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Cell growth and division must be coordinated to maintain a stable cell size, but how this coordination is implemented in multicellular tissues remains unclear. In unicellular eukaryotes, autonomous cell size control mechanisms couple cell growth and ... ...

    Abstract Cell growth and division must be coordinated to maintain a stable cell size, but how this coordination is implemented in multicellular tissues remains unclear. In unicellular eukaryotes, autonomous cell size control mechanisms couple cell growth and division with little extracellular input. However, in multicellular tissues we do not know if autonomous cell size control mechanisms operate the same way or whether cell growth and cell cycle progression are separately controlled by cell-extrinsic signals. Here, we address this question by tracking single epidermal stem cells growing in adult mice. We find that a cell-autonomous size control mechanism, dependent on the RB pathway, sets the timing of S phase entry based on the cell's current size. Cell-extrinsic variations in the cellular microenvironment affect cell growth rates but not this autonomous coupling. Our work reassesses long-standing models of cell cycle regulation within complex metazoan tissues and identifies cell-autonomous size control as a critical mechanism regulating cell divisions
    Language English
    Publishing date 2024-04-11
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.04.09.588781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The G1/S transition is promoted by Rb degradation via the E3 ligase UBR5.

    Zhang, Shuyuan / Valenzuela, Lucas Fuentes / Zatulovskiy, Evgeny / Mangiante, Lise / Curtis, Christina / Skotheim, Jan M

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Mammalian cells make the decision to divide at the G1/S transition in response to diverse signals impinging on the retinoblastoma protein Rb, a cell cycle inhibitor and tumor suppressor. Rb is inhibited by two parallel pathways. In the canonical pathway, ...

    Abstract Mammalian cells make the decision to divide at the G1/S transition in response to diverse signals impinging on the retinoblastoma protein Rb, a cell cycle inhibitor and tumor suppressor. Rb is inhibited by two parallel pathways. In the canonical pathway, Cyclin D-Cdk4/6 kinase complexes phosphorylate and inactivate Rb. In the second, recently discovered pathway, Rb's concentration decreases during G1 to promote cells progressing through the G1/S transition. However, the mechanisms underlying this second pathway are unknown. Here, we found that Rb's concentration drop in G1 and recovery in S/G2 is controlled by phosphorylation-dependent protein degradation. In early G1 phase, un- and hypo-phosphorylated Rb is targeted by the E3 ligase UBR5.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.10.03.560768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Sulfur migration mechanism of pig manure in supercritical water: A combined experimental and DFT study.

    Zhang, Shuyuan / Du, Mingming / Ge, Hui / Rong, Siqi / Chen, Yunan / Guo, Liejin

    Journal of hazardous materials

    2024  Volume 471, Page(s) 134376

    Abstract: Pig manure (PM) is a high concentration organic waste rich in sulfur, and its biofuel contains various sulfur-containing pollutants, which reduces the safety of the products. Supercritical water (SCW) can dissolve most organic matter, which is a ... ...

    Abstract Pig manure (PM) is a high concentration organic waste rich in sulfur, and its biofuel contains various sulfur-containing pollutants, which reduces the safety of the products. Supercritical water (SCW) can dissolve most organic matter, which is a technology worthy of further study. In order to reduce sulfur pollution in the process of PM resource utilization and better control the conversion path of sulfur, it is necessary to explore the migration mechanism of sulfur in the whole PM-SCW gasification process. The experimental results indicated that H
    Language English
    Publishing date 2024-04-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2024.134376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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