LIVIVO - Search results -

Search results

Result 1 - 10 of total 596

Search options

Article ; Online: Anaerobic photoinduced Cu(0/I)-mediated Glaser coupling in a radical pathway.

Zhang, Siqi / Zhao, Liang

2023 Volume 14, Issue 1, Page(s) 6741

Abstract: The reaction mechanism of the historic copper-catalyzed Glaser coupling has been debated to be based on redox cycles of Cu ions in specific oxidation states or on a radical mechanism based on Cu(0)/Cu(I). Here, the authors demonstrate two coexisting ... ...

Abstract	The reaction mechanism of the historic copper-catalyzed Glaser coupling has been debated to be based on redox cycles of Cu ions in specific oxidation states or on a radical mechanism based on Cu(0)/Cu(I). Here, the authors demonstrate two coexisting Glaser coupling pathways which can be differentiated by anaerobic/irradiation or aerobic reaction conditions. Without O
Language	English
Publishing date	2023-10-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-023-42602-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: [Replication and expression of oncolytic herpes simplex virus type Ⅱ in tumors].

Cai, Qiying / Zhang, Siqi / Liu, Huajuan / Liu, Binlei

Sheng wu gong cheng xue bao = Chinese journal of biotechnology

2024 Volume 40, Issue 2, Page(s) 585–595

Abstract: This study aimed to measure the duration and replication level of oncolytic herpes simplex virus type 2 (oHSV2) at the tumor injection site in BALB/c mice. Additionally, the expression level of human granulocyte macrophage colony-stimulating factor (hGM- ... ...

Abstract	This study aimed to measure the duration and replication level of oncolytic herpes simplex virus type 2 (oHSV2) at the tumor injection site in BALB/c mice. Additionally, the expression level of human granulocyte macrophage colony-stimulating factor (hGM-CSF) and HSV-2 antibody in the serum was also measured. High and low doses of oHSV2-Fluc (firefly luciferin, Fluc) were injected into the mice's tumors to track the change and duration of fluorescence expression. The copy number of oHSV2 gene in tumor tissues was determined using quantitative real-time polymerase chain reaction (qPCR). Enzyme linked immunosorbent assay (ELISA) was used to detect the expression of hGM-CSF and HSV-2 antibody in the serum. The tumor volume in the high-dose group was significantly lower than that in the control group (
MeSH term(s)	Mice ; Animals ; Humans ; Herpesvirus 2, Human/genetics ; Neoplasms
Language	Chinese
Publishing date	2024-02-18
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1042206-7
ISSN	1872-2075 ; 1042-749X
ISSN (online)	1872-2075
ISSN	1042-749X
DOI	10.13345/j.cjb.230619
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3505: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Subsurface phytoplankton vertical structure from lidar observation during SCS summer monsoon onset.

Zhang, Siqi / Chen, Peng

Optics express

2022 Volume 30, Issue 11, Page(s) 17665–17679

Abstract: Subsurface phytoplankton vertical structure was observed for the first time by lidar during the onset of the SCS summer monsoon. Based on the lidar data that were obtained by continuous day-and-night measurements over a two-week period, a hybrid ... ...

Abstract	Subsurface phytoplankton vertical structure was observed for the first time by lidar during the onset of the SCS summer monsoon. Based on the lidar data that were obtained by continuous day-and-night measurements over a two-week period, a hybrid retrieval method to determine the vertical structure of the seawater chlorophyll-a concentrations using lidar data was proposed. We compared the data obtained from the lidar retrievals with the ocean color data and studied the spatial variations and hourly diurnal variations in the subsurface chlorophyll-a maximum layer (SCML). The significant changes in the depth of the SCML in the SCS may be due to the variations in light availability and nutrient supply during the onset of the SCS summer monsoon. The preliminary results indicated that lidar measurements allow the submesoscale oceanic dynamics mechanisms to be understood from a new perspective.
MeSH term(s)	Chlorophyll ; Chlorophyll A ; Oceans and Seas ; Phytoplankton ; Seasons ; Seawater/chemistry
Chemical Substances	Chlorophyll (1406-65-1) ; Chlorophyll A (YF5Q9EJC8Y)
Language	English
Publishing date	2022-06-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.453094
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Differential privacy medical data publishing method based on attribute correlation.

Zhang, Siqi / Li, Xiaohui

Scientific reports

2022 Volume 12, Issue 1, Page(s) 15725

Abstract: The advent of the era of big data promotes the further development of medicine, and data release is an important step in it. The existing medical data release methods mostly use the k-anonymity model as the basis for data protection. With the advancement ...

Abstract	The advent of the era of big data promotes the further development of medicine, and data release is an important step in it. The existing medical data release methods mostly use the k-anonymity model as the basis for data protection. With the advancement of technology, anonymous models are progressively less resistant to consistency attacks and background knowledge attacks. In order to better protect the private information of patients, this paper makes two major contributions: (1) The method of calculating the correlation between attributes is used to ensure the validity of the data after the data is released; (2) On the basis of the previous step, combined with the difference privacy-preserving model and tree model, this paper proposes an attribute association-based differential privacy classification tree data publishing method (ACDP-Tree). In this paper, simulation experiments are carried out on real medical data sets. The experimental results show that the algorithm ensures the validity and availability of the data to a certain extent while ensuring that the patient's privacy is not leaked.
MeSH term(s)	Algorithms ; Computer Security ; Health Services ; Humans ; Privacy ; Publishing
Language	English
Publishing date	2022-09-21
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-19544-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Effects of quercetin and l-ascorbic acid on heterocyclic amines and advanced glycation end products production in roasted eel and lipid-mediated inhibition mechanism analysis.

Chu, Junbo / Lin, Songyi / Yuan, Yi / Zhang, Siqi / Zhang, Simin

Food chemistry

2024 Volume 441, Page(s) 138394

Abstract: Eel is a commercially important marine fish, frequently featured as sushi or roasted preparations. This study determined the formation of heterocyclic amines (HAs) and advanced glycation end products (AGEs) in roasted eel and evaluated the inhibitory ... ...

Abstract	Eel is a commercially important marine fish, frequently featured as sushi or roasted preparations. This study determined the formation of heterocyclic amines (HAs) and advanced glycation end products (AGEs) in roasted eel and evaluated the inhibitory mechanism of quercetin and l-ascorbic acid on their formation. The results indicate a respective reduction of 75.07% and 84.72% in total HAs, alongside a decline of 23.03% and 39.14% in AGEs. Additionally, fundamental parameters of roasted eel, lipid oxidation indicators and precursors were measured to elucidate the mechanisms and impact of natural antioxidants on HAs and AGEs formation in roasted eel. Furthermore, endeavors were made to probe into the molecular mechanisms governing the influence of key differential lipids on the generation of HAs and AGEs through lipid-mics analysis. This research emphasizes the potential of natural antioxidants in preventing harmful substances formation during eel thermal processing, which is helpful to food manufacturers for healthier food production.
MeSH term(s)	Animals ; Quercetin/pharmacology ; Ascorbic Acid/pharmacology ; Antioxidants/pharmacology ; Amines ; Glycation End Products, Advanced/pharmacology ; Eels ; Lipids
Chemical Substances	Quercetin (9IKM0I5T1E) ; Ascorbic Acid (PQ6CK8PD0R) ; Antioxidants ; Amines ; Glycation End Products, Advanced ; Lipids
Language	English
Publishing date	2024-01-07
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2024.138394
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 3634: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The medium-term impact of a micronutrient powder intervention on anemia among young children in Rural China.

Zhang, Siqi / Wang, Lei / Luo, Renfu / Rozelle, Scott / Sylvia, Sean

BMC public health

2024 Volume 24, Issue 1, Page(s) 426

Abstract: Background: Poor development of young children is a common issue in developing countries and it is well established that iron deficiency anemia is one of the risk factors. Research has shown that iron deficiency is a common micronutrient deficiency ... ...

Abstract	Background: Poor development of young children is a common issue in developing countries and it is well established that iron deficiency anemia is one of the risk factors. Research has shown that iron deficiency is a common micronutrient deficiency among children in rural China and can result in anemia. A previous paper using data from the same trial as those used in the current study, but conducted when sample children were younger, found that after 6 months of providing caregivers of children 6-11 months of age free access to iron-rich micronutrient powder (MNP) increased the hemoglobin concentrations (Hb) of their children. However, no effects were found 12 and 18 months after the intervention. The current study followed up the children four years after the start of the original intervention (when the children were 4-5 years old) and aims to assess the medium-term impacts of the MNP program on the nutritional status of the sample pre-school-aged children, including their levels of Hb, the prevalence of anemia, and the dietary diversity of the diets of the children. Methods: At baseline, this study sampled 1,802 children aged 6-11 months in rural Western China. The intervention lasted 18 months. In this medium-term follow-up study that successfully followed 81% (n = 1,464) of children (aged 49-65 months) from the original study population 4 years after the start of the intervention, we used both intention-to-treat (ITT) effect and average treatment on the treated effect (ATT) analyses to assess the medium-term impacts of the MNP distribution program on the nutritional status of sample children. Results: The ITT analysis shows that the MNP intervention decreased the prevalence of anemia of young children in the medium run by 8% (4 percentage points, p < 0.1). The ATT analysis shows that consuming 100 (out of 540) MNP sachets during the initial intervention led to a decrease in anemia of 4% (2 percentage points, p < 0.1). Among children with moderate anemia at baseline (Hb < 100 g/L), the intervention reduced the probability of anemia by 45% (9 percentage points, p < 0.1), and, for those families that complied by consuming 100 (out of 540) sachets, a 25% (5 percentage points, p < 0.05) reduction in the anemia rate was found. The MNP intervention also led to a persistent increase in dietary diversity among children that were moderately anemic at baseline. The results from the quantile treatment effect analysis demonstrated that children with lower Hb levels at baseline benefited relatively more from the MNP intervention. Conclusions: The findings of the current study reveal that the MNP intervention has medium-term effects on the nutritional status of children in rural China. The impacts of the MNP program were relatively higher for children that initially had more severe anemia levels. Hence, the implications of this study are that programs that aim to increase caregiver knowledge of nutrition and improve their feeding practices should be encouraged across rural China. Families, policymakers, and China's society overall need to continue to pay more attention to problems of childhood anemia in rural areas. This is particularly crucial for families with moderately anemic children at an early age as it can significantly contribute to improving the anemia status of children across rural areas of China. Trial registration: ISRCTN44149146 (15/04/2013).
MeSH term(s)	Child ; Humans ; Child, Preschool ; Infant ; Micronutrients ; Powders ; Follow-Up Studies ; Dietary Supplements ; Anemia/epidemiology ; Anemia/prevention & control ; Anemia, Iron-Deficiency/epidemiology ; Anemia, Iron-Deficiency/prevention & control ; China/epidemiology
Chemical Substances	Micronutrients ; Powders
Language	English
Publishing date	2024-02-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-024-17895-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Discrepancies in MR- and CT-Based Femoral Version Measurements Despite Strong Correlations.

Zhang, Siqi / Liu, Ke / Gao, Guanying / Lang, Ning / Xu, Yan

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

2024

Abstract: Purpose: To determine the correlation and classification consistency of femoral version measurements between magnetic resonance (MR) and computed tomography (CT) using 4 commonly used measurement methods.: Methods: A retrospective study was performed ...

Abstract	Purpose: To determine the correlation and classification consistency of femoral version measurements between magnetic resonance (MR) and computed tomography (CT) using 4 commonly used measurement methods. Methods: A retrospective study was performed on patients with femoroacetabular impingement (FAI) who received preoperative CT and MR imaging assessment of the surgical hip and ipsilateral distal femur. Femoral version was measured using the Murphy method, the oblique method, the Reikerås method, and the Lee method. Intra- and inter-rater agreements were calculated. Linear regression and Bland-Altman analysis were performed for measurements using different imaging modalities and measurement methods. Femoral version measurements within the lower quartile, the middle 2 quartiles, and the upper quartile were classified into different groups based on their percentile within the sample population. Classification consistency rates between modalities and methods were calculated and compared. Results: Fifty-three patients (39.4 ± 9.1 years; 32 female) were included for analysis. Intra- and inter-rater reliability were high for all modalities and methods (intrarater intraclass correlation coefficient [ICC] range, 0.963-0.993; inter-rater ICC range, 0.871-0.960). MR- and CT-based femoral version measurements showed strong correlations for all methods, with the Lee method demonstrating the strongest association (r = 0.904), while the oblique method exhibited the lowest correlation (r = 0.684) (all P < .001). MR-based measurements were smaller than CT-based measurements, with mean differences ranging from 4.5° to 10.3°. Classification consistency between MR and CT ranged from 51% to 74%, whereas the consistency between different measurement methods ranged from 68% to 85%. Conclusions: While strong correlations were observed between MR- and CT-based femoral version measurements, MR-based measurements were significantly smaller than their CT counterparts. Classification consistency between the modalities was moderate to high. Measurements between different methods showed strong correlations with high consistency rates. Level of evidence: Level III, retrospective case series.
Language	English
Publishing date	2024-01-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	632528-2
ISSN	1526-3231 ; 0749-8063
ISSN (online)	1526-3231
ISSN	0749-8063
DOI	10.1016/j.arthro.2023.12.025
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2046: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Pricing Mechanism of Charging Pile Power Supply Market——Based on RTP Theory and Price Discrimination Model

Ding Shiyao / Zhang Siqi

E3S Web of Conferences, Vol 275, p

2021 Volume 01073

Abstract: Based on the data of monopoly enterprises in China’s new energy charging pile power retail market, this paper explores the application of RTP differential pricing in new areas. First of all, from the perspective of business, this paper constructs the ... ...

Abstract	Based on the data of monopoly enterprises in China’s new energy charging pile power retail market, this paper explores the application of RTP differential pricing in new areas. First of all, from the perspective of business, this paper constructs the incentive cost model of low period which can minimize the supply pressure of power sales enterprises. Then, from the perspective of charging consumers, based on the assumption of user’s conversion cost, an improved demand response model is established according to the price elasticity. The paper is to consider the premise of maximizing social welfare, in the supply and demand of both sides to improve the pressure of electricity measurement, to minimize the operation and maintenance costs in peak and trough period.
Keywords	Environmental sciences ; GE1-350
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Differentiation and Characterization of Cystic Fibrosis Transmembrane Conductance Regulator Knockout Human Pluripotent Stem Cells into Salivary Gland Epithelial Progenitors.

Yan, Shuang / Zhang, Yifei / Zhang, Siqi / Wei, Shicheng

International journal of stem cells

2023 Volume 16, Issue 4, Page(s) 394–405

Abstract: The differentiation of pluripotent stem cells has been used to study disease mechanisms and development. We previously described a method for differentiating human pluripotent stem cells (hPSCs) into salivary gland epithelial progenitors (SGEPs). Here, ... ...

Abstract	The differentiation of pluripotent stem cells has been used to study disease mechanisms and development. We previously described a method for differentiating human pluripotent stem cells (hPSCs) into salivary gland epithelial progenitors (SGEPs). Here, cystic fibrosis transmembrane conductance regulator (CFTR) knockout hPSCs were differentiated into SGEPs derived from CFTR knockout hESCs (CF-SGEPs) using the same protocol to investigate whether the hPSC-derived SGEPs can model the characteristics of CF. CF-a disease that affects salivary gland (SG) function-is caused by mutations of the
Language	English
Publishing date	2023-09-06
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2914134-5
ISSN	2005-5447 ; 2005-3606
ISSN (online)	2005-5447
ISSN	2005-3606
DOI	10.15283/ijsc23036
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Current and future outlook of loaded components in hydrogel composites for the treatment of chronic diabetic ulcers.

Cui, Jiaming / Zhang, Siqi / Cheng, Songmiao / Shen, Hai

Frontiers in bioengineering and biotechnology

2023 Volume 11, Page(s) 1077490

Abstract: Due to recalcitrant microangiopathy and chronic infection, traditional treatments do not easily produce satisfactory results for chronic diabetic ulcers. In recent years, due to the advantages of high biocompatibility and modifiability, an increasing ... ...

Abstract	Due to recalcitrant microangiopathy and chronic infection, traditional treatments do not easily produce satisfactory results for chronic diabetic ulcers. In recent years, due to the advantages of high biocompatibility and modifiability, an increasing number of hydrogel materials have been applied to the treatment of chronic wounds in diabetic patients. Research on composite hydrogels has received increasing attention since loading different components can greatly increase the ability of composite hydrogels to treat chronic diabetic wounds. This review summarizes and details a variety of newly loaded components currently used in hydrogel composites for the treatment of chronic diabetic ulcers, such as polymer/polysaccharides/organic chemicals, stem cells/exosomes/progenitor cells, chelating agents/metal ions, plant extracts, proteins (cytokines/peptides/enzymes) and nucleoside products, and medicines/drugs, to help researchers understand the characteristics of these components in the treatment of diabetic chronic wounds. This review also discusses a number of components that have not yet been applied but have the potential to be loaded into hydrogels, all of which play roles in the biomedical field and may become important loading components in the future. This review provides a "loading component shelf" for researchers of composite hydrogels and a theoretical basis for the future construction of "all-in-one" hydrogels.
Language	English
Publishing date	2023-02-13
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2719493-0
ISSN	2296-4185
ISSN	2296-4185
DOI	10.3389/fbioe.2023.1077490
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito