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  1. Article ; Online: Response of rhizosphere microenvironment to coupling of climate warming and soil pollution

    Lei Na / Zhang Weihua

    E3S Web of Conferences, Vol 375, p

    2023  Volume 01010

    Abstract: With the development of industrialization, the pollution of heavy metals in soil, such as lead (Pb) and cadmium (Cd), has become increasingly serious. On the other hand, the century old climate warming is considered to be the result of the significant ... ...

    Abstract With the development of industrialization, the pollution of heavy metals in soil, such as lead (Pb) and cadmium (Cd), has become increasingly serious. On the other hand, the century old climate warming is considered to be the result of the significant increase in the concentration of greenhouse gases, such as CO2, in the atmosphere. These changes will affect the function and stability of the terrestrial ecosystem. Therefore, in recent years, there are more and more studies on the effects of heavy metal pollution and elevated atmospheric CO2 concentration on plants. But most of them focus on the study of the aboveground part of herbaceous plants under the action of single factor, and the study of the soil microenvironment of woody plants under the combined action of these environmental factors is relatively less. This study summarized the response of rhizosphere microenvironment to the coupling of climate warming and soil pollution, in order to provide theoretical reference for improving soil quality and ecological environment.
    Keywords climate warming ; soil pollution ; rhizosphere microenvironment ; coupling effect ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Autoimmune Basal Ganglia Encephalitis Associated With Anti-N-methyl-d-Aspartate Receptor Antibodies in Children.

    Zhang, Weihua / Ren, Changhong / Wu, Yun

    Pediatric neurology

    2024  Volume 153, Page(s) 65–67

    MeSH term(s) Child ; Humans ; Encephalitis/complications ; Basal Ganglia/diagnostic imaging ; Receptors, Amino Acid ; Anti-N-Methyl-D-Aspartate Receptor Encephalitis/complications ; Receptors, N-Methyl-D-Aspartate ; Autoantibodies ; Hashimoto Disease
    Chemical Substances aspartic acid receptor ; Receptors, Amino Acid ; Receptors, N-Methyl-D-Aspartate ; Autoantibodies
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Letter
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2024.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2260: Show issues Location:
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  3. Article: Effects of Different Volumes of Ropivacaine for Pericapsular Nerve Group Block on Incidence of Quadriceps Weakness and Analgesic Efficacy Following Hip Arthroplasty: A Randomized Controlled Trial.

    Wen, Huaichang / Zhang, Weihua / Wang, Yi / Lu, Meijing

    Pain and therapy

    2024  

    Abstract: Introduction: The pericapsular nerve group (PENG) block has been shown to be an effective approach to alleviating pain and reducing the need for opioids among older adults following hip surgery, with possible motor-sparing effects. No reports to date, ... ...

    Abstract Introduction: The pericapsular nerve group (PENG) block has been shown to be an effective approach to alleviating pain and reducing the need for opioids among older adults following hip surgery, with possible motor-sparing effects. No reports to date, however, have described appropriate ropivacaine volumes for use in the context of PENG block. The present prospective randomized controlled study was thus developed to assess the quadriceps muscle strength and analgesic efficacy associated with PENG block performed using three different volumes of 0.33% ropivacaine following general anesthesia in older adults undergoing hip arthroplasty.
    Methods: In this prospective randomized double-blind controlled clinical study, 60 patients were assigned at random to undergo ultrasound-guided PENG block for hip arthroplasty using different volumes of ropivacaine. Specifically, these patients were administered 10 ml (Group A, n = 20), 20 ml (Group B, n = 20), or 30 ml (Group C, n = 20) of 0.33% ropivacaine. Quadriceps muscle strength was evaluated at 6 h post-surgery. Visual analog scale (VAS) scores at rest and with movement were assessed at 4, 6, 12, and 24 h post-surgery. Block duration, adverse event incidence, and patient satisfaction were evaluated at 24 h post-surgery.
    Results: Quadriceps motor block incidence rates at 6 h post-surgery in the 10 ml, 20 ml, and 30 ml groups were 5%, 20%, and 75%, respectively. Quadriceps muscle weakness at 6 h post-surgery was significantly more common in the 30 ml group relative to the others (p < 0.001). Patients administered 10 ml 0.33% ropivacaine exhibited significantly higher VAS pain scores at rest and with movement relative to those patients in the 20 ml and 30 ml treatment groups at all time points (p < 0.05). No apparent differences in analgesic efficacy were observed when comparing the 20 ml and 30 ml groups at 4, 6, 12, and 24 h post-surgery. No significant differences in block duration, satisfaction, or adverse event incidence were observed among groups.
    Conclusions: The preservation of motor function in the 20 ml 0.33% ropivacaine group was superior to that in the 30 ml 0.33% ropivacaine group. Relative to the group that received 10 ml 0.33% ropivacaine during PENG block, those elderly patients administered 20 ml and 30 ml volumes of 0.33% ropivacaine experienced superior postoperative pain relief following hip arthroplasty.
    Language English
    Publishing date 2024-03-13
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2701614-6
    ISSN 2193-651X ; 2193-8237
    ISSN (online) 2193-651X
    ISSN 2193-8237
    DOI 10.1007/s40122-024-00590-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Application of"Spinal cord fusion" in spinal cord injury repair and its neurological mechanism.

    Shen, Tingting / Zhang, Weihua / Wang, Xiaogang / Ren, Xiaoping

    Heliyon

    2024  Volume 10, Issue 8, Page(s) e29422

    Abstract: Spinal cord injury (SCI) is a severely disabling and catastrophic condition that poses significant global clinical challenges. The difficulty of SCI repair results from the distinctive pathophysiological mechanisms, which are characterised by limited ... ...

    Abstract Spinal cord injury (SCI) is a severely disabling and catastrophic condition that poses significant global clinical challenges. The difficulty of SCI repair results from the distinctive pathophysiological mechanisms, which are characterised by limited regenerative capacity and inadequate neuroplasticity of the spinal cord. Additionally, the formation of cystic cavities and astrocytic scars after SCI further obstructs both the ascending and descending neural conduction pathways. Consequently, the urgent challenge in post-SCI recovery lies in repairing the damaged spinal cord to reconstruct a functional and intact neural conduction circuit. In recent years, significant advancements in biological tissue engineering technology and novel therapies have resulted in a transformative shift in the field of SCI repair. Currently, SCI treatment primarily involves drug therapy, stem cell therapy, the use of biological materials, growth factors, and other approaches. This paper comprehensively reviews the progress in SCI research over the years, with a particular focus on the concept of "Spinal Cord Fusion" as a promising technique for SCI reconstruction. By discussing this important research progress and the neurological mechanisms involved, our aim is to help solve the problem of SCI repair as soon as possible and to bring new breakthroughs in the treatment of paraplegia after SCI.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Discovery of Dehydroabietylamine Derivatives as Antibacterial and Antifungal Agents.

    Zhang, Shu-Guang / Wan, Yu-Qiang / Zhang, Wei-Hua

    Journal of natural products

    2024  Volume 87, Issue 4, Page(s) 924–934

    Abstract: A diverse array of biologically active derivatives was derived by modifying the chemically active sites of dehydroabietylamine. Herein, we describe the synthesis of a new series of C-19-arylated dehydroabietylamine derivatives using a palladium-catalyzed ...

    Abstract A diverse array of biologically active derivatives was derived by modifying the chemically active sites of dehydroabietylamine. Herein, we describe the synthesis of a new series of C-19-arylated dehydroabietylamine derivatives using a palladium-catalyzed C(sp
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/chemical synthesis ; Antifungal Agents/pharmacology ; Antifungal Agents/chemistry ; Abietanes/pharmacology ; Abietanes/chemistry ; Molecular Structure ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Escherichia coli/drug effects
    Chemical Substances Anti-Bacterial Agents ; Antifungal Agents ; Abietanes ; dehydroabietylamine (33289O147P)
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/acs.jnatprod.3c01213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  6. Article ; Online: The Parasitologists and Medical Educators of Peking Union Medical College Shown on the Old Postcards

    WEI Yuhang / LI Zeya / YANG Shuyue / ZHANG Weihua

    Xiehe Yixue Zazhi, Vol 14, Iss 1, Pp 225-

    2023  Volume 228

    Abstract: The information on the two old postcards sent from Peking Union Medical College was studied. Henry E. Meleney and H.F. Hsü, the parasitologists and medical educators of Peking Union Medical College, were introduced. Their experiences in scientific ... ...

    Abstract The information on the two old postcards sent from Peking Union Medical College was studied. Henry E. Meleney and H.F. Hsü, the parasitologists and medical educators of Peking Union Medical College, were introduced. Their experiences in scientific research and achievements were reviewed. The professional ethics of serving patients and the scientific spirit with rigorous research of the medical scientists are of practical educational significance.
    Keywords medical parasitology ; schistosome ; clonorchis sinesis ; infectious disease ; Medicine ; R
    Language Chinese
    Publishing date 2023-01-01T00:00:00Z
    Publisher Editorial Office of Medical Journal of Peking Union Medical College Hospital
    Document type Article ; Online
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  7. Article ; Online: Multikernel

    Song Yijing / Dai Huasheng / Jiang Jinhu / Zhang Weihua

    Security and Safety, Vol 2, p

    Operating system solution to generalized functional safety

    2023  Volume 2023007

    Abstract: With the trend of digitalization, intelligence, and networking sweeping the world, functional safety and cyber security are increasingly intertwined and overlapped, evolving into the issue of generalized functional safety. Traditional system reliability ... ...

    Abstract With the trend of digitalization, intelligence, and networking sweeping the world, functional safety and cyber security are increasingly intertwined and overlapped, evolving into the issue of generalized functional safety. Traditional system reliability technology and network defense technology cannot provide quantifiable design implementation theories and methods. As the cornerstone of software systems, operating systems in particular are in need of efficient safety assurance. The DHR architecture is a mature and comprehensive solution, and it is necessary to implement an OS-level DHR architecture, for which the multi-kernel operating system is a good carrier. The multi-kernel operating system takes the kernel as the processing scenario element and constructs redundancy, heterogeneity, and dynamism on the kernel, so it has the generalized robustness of the DHR architecture. This article analyzes the significance and requirements of OS-level DHR architecture, and systematically explains how the multi-kernel operating system responds to the requirements of OS-level DHR architecture by analyzing the technical routes of multi-kernel operating systems and develops an operating system solution idea for the generalized functionally safety.
    Keywords metaverse ; new infrastructure ; security base ; highly trusted network ; trusted identiry ; trusted circulation of data ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 303
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Pulmonary arterial sarcoma: A case report.

    Wang, Yin / Rong, Chunyan / Liu, Jingwei / Liu, Xuhan / Zhang, Weihua

    Medicine

    2024  Volume 103, Issue 8, Page(s) e37194

    Abstract: Rationale: Pulmonary artery sarcoma (PAS) is a rare malignant tumor primarily originating from the pulmonary artery's intima or subintima. Approximately one-third of cases are classified as undifferentiated type. Its clinical manifestations lack ... ...

    Abstract Rationale: Pulmonary artery sarcoma (PAS) is a rare malignant tumor primarily originating from the pulmonary artery's intima or subintima. Approximately one-third of cases are classified as undifferentiated type. Its clinical manifestations lack specificity, dyspnea is the main symptom but can also present with chest pain, cough, hemoptysis, and other discomforts, making it prone to misdiagnosis as pulmonary embolism (PE).
    Patient concerns: A 50-year-old woman was admitted to the hospital with "dyspnea for more than 3 months, aggravated for 2 days," and computed tomography pulmonary angiography suggesting "bilateral multiple pulmonary embolisms."
    Diagnoses: The patient was initially misdiagnosed as PE, and was later definitively diagnosed as undifferentiated pleomorphic sarcoma of the pulmonary artery by pathologic biopsy.
    Interventions and outcomes: The patient was initially treated with anticoagulant therapy, but her dyspnea was not relieved. After that, she underwent positron emission computed tomography (PET-CT) and other investigations, which suggested the possibility of PAS, and then she underwent pulmonary endarterectomy to remove the lesion, which relieved her symptoms and was advised to seek further medical attention from the Department of Oncology and Department of Radiotherapy.
    Lessons: PAS can be easily misdiagnosed as PE. If a diagnosis of PE is made, but anticoagulation or even thrombolytic therapy proves ineffective, and there is no presence of PE causative factors such as deep vein thrombosis in the lower extremities, or D-dimer levels are not high, one should be cautious and consider the possibility of PAS.
    MeSH term(s) Humans ; Female ; Middle Aged ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/pathology ; Positron Emission Tomography Computed Tomography ; Hypertension, Pulmonary/complications ; Pulmonary Embolism/drug therapy ; Lung Neoplasms/pathology ; Soft Tissue Neoplasms/pathology ; Dyspnea/etiology ; Dyspnea/pathology ; Sarcoma/diagnosis ; Sarcoma/therapy ; Sarcoma/complications
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.171: Show issues Location:
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  9. Article ; Online: The Construction of lncRNA/circRNA-miRNA-mRNA Networks Reveals Functional Genes Related to Growth Traits in

    Bai, Qingsong / Shi, Lingling / Li, Kejian / Xu, Fang / Zhang, Weihua

    International journal of molecular sciences

    2024  Volume 25, Issue 4

    Abstract: ... Schima ... ...

    Abstract Schima superba
    MeSH term(s) Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Circular/genetics ; RNA, Long Noncoding/genetics ; Plant Breeding ; Gene Regulatory Networks
    Chemical Substances MicroRNAs ; RNA, Messenger ; RNA, Circular ; RNA, Long Noncoding
    Language English
    Publishing date 2024-02-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25042171
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  10. Article: [Professor

    Wang, Jian / Zhang, Qing-Xin / Zhang, Wei-Hua

    Zhongguo zhen jiu = Chinese acupuncture & moxibustion

    2023  Volume 43, Issue 3, Page(s) 333–335

    Abstract: The paper summarizes ... ...

    Abstract The paper summarizes professor
    MeSH term(s) Humans ; Vascular Surgical Procedures ; Chronic Pain ; Nociceptive Pain ; Acupuncture Therapy ; Muscles
    Language Chinese
    Publishing date 2023-02-28
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 0255-2930
    ISSN 0255-2930
    DOI 10.13703/j.0255-2930.20211204-k0001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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