LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 83

Search options

  1. Article: Dysphagia in a patient with ankylosing spondylitis: A case report.

    Wang, Xin-Wen / Zhang, Wen-Zhi

    World journal of clinical cases

    2020  Volume 9, Issue 7, Page(s) 1639–1645

    Abstract: Background: Ankylosing spondylitis (AS) is a systematic and rheumatic disease, which causes multiple symptoms. However, dysphagia due to the formation of a giant anterior cervical osteophyte is rare in patients with AS.: Case summary: We present the ... ...

    Abstract Background: Ankylosing spondylitis (AS) is a systematic and rheumatic disease, which causes multiple symptoms. However, dysphagia due to the formation of a giant anterior cervical osteophyte is rare in patients with AS.
    Case summary: We present the case of a 65-year-old male patient who was diagnosed with AS and visited the hospital with a complaint of progressive dysphagia. The appropriate imaging examinations indicated that a giant anterior cervical osteo-phyte at C3-4 caused esophageal compression, which led to dysphagia. An operation for resection was performed without complications.
    Conclusion: This case demonstrates that a large cervical osteophyte may be the cause of dysphagia in patients with AS, and early accurate diagnosis and surgical treat-ment are very important for the improvement of symptoms. Anterior cervical discectomy and fusion are extremely effective and should be taken into consideration.
    Language English
    Publishing date 2020-11-10
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v9.i7.1639
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Interleukin-4-induced FABP4 promotes lipogenesis in human skeletal muscle cells by activating the PPAR γ signaling pathway.

    Wang, Xin-Wen / Sun, Yong-Jin / Chen, Xiao / Zhang, Wen-Zhi

    Cell biochemistry and biophysics

    2022  Volume 80, Issue 2, Page(s) 355–366

    Abstract: Chronic low back pain (CLBP) is a common symptom of lumbar degenerative disease. Degeneration of the lumbar paravertebral muscles causes a loss of muscle mass and strength, which is a vital factor causing CLBP and often accompanied by lipid infiltration. ...

    Abstract Chronic low back pain (CLBP) is a common symptom of lumbar degenerative disease. Degeneration of the lumbar paravertebral muscles causes a loss of muscle mass and strength, which is a vital factor causing CLBP and often accompanied by lipid infiltration. Tandem mass spectrometry (TMT) was used to identify differentially expressed proteins in lipid-infiltrated and normal muscles. The results show that fatty acid binding protein 4 (FABP4) participated in the peroxisome proliferator-activated receptor-γ (PPAR γ) signaling pathway as an up-regulated protein, which is related to lipogenesis in diverse cells. In addition, chronic inflammation is believed to be involved in lumbar muscle degeneration and lipogenesis, with interleukin-4 (IL-4) considered as the predominant contributor. In present study, we investigate the effect of FABP4 on lipogenesis in human skeletal muscle cells (HSMCs) stimulated by Interleukin-4 (IL-4) and explore the mechanistic basis. We found expression level of FABP4 in lipid-infiltrated muscles was significantly higher than that in normal muscles. Lipogenesis in HSMCs could be increased by IL-4 treatment, as well as by FABP4 overexpression. FABP4 inhibition suppressed IL-4-mediated lipogenesis in HSMCs, whereas the PPAR γ inhibitor alleviated lipogenesis in both IL-4-treated and FABP4-overexpressed HSMCs. Collectively, the results indicate that FABP4 induces lipogenesis in HSMCs stimulated with IL-4 via activating the PPAR γ signaling pathway. Our study offers a detailed perspective on the pathogenesis of muscle lipid infiltration and provides a potential target for the clinical treatment strategy of muscle lipid infiltration and CLBP.
    MeSH term(s) Fatty Acid-Binding Proteins/genetics ; Humans ; Interleukin-4/metabolism ; Interleukin-4/pharmacology ; Lipids ; Lipogenesis ; Muscle, Skeletal/metabolism ; PPAR gamma/metabolism ; Signal Transduction
    Chemical Substances FABP4 protein, human ; Fatty Acid-Binding Proteins ; Lipids ; PPAR gamma ; Interleukin-4 (207137-56-2)
    Language English
    Publishing date 2022-02-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1357904-6
    ISSN 1559-0283 ; 1085-9195
    ISSN (online) 1559-0283
    ISSN 1085-9195
    DOI 10.1007/s12013-022-01063-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Stress Monitoring of Segment Structure during the Construction of the Small-Diameter Shield Tunnel.

    Ding, Liang / Sun, Yi-Jie / Zhang, Wen-Zhi / Bi, Gang / Xu, Hong-Zhong

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 19

    Abstract: Segmental stress during the construction process plays a pivotal role in assessing the safety and quality of shield tunnels. Fiber Bragg grating (FBG) sensing technology has been proposed for tunnel segment stress monitoring. A laboratory test was ... ...

    Abstract Segmental stress during the construction process plays a pivotal role in assessing the safety and quality of shield tunnels. Fiber Bragg grating (FBG) sensing technology has been proposed for tunnel segment stress monitoring. A laboratory test was conducted to validate the reliable strain measurement of FBG sensors. The field in situ monitoring of a sewerage shield tunnel was carried out to examine the longitudinal and circumferential stresses experienced by the segments throughout the construction phase. The cyclic fluctuations in stress were found to be synchronized with the variations in shield thrust. A comparison was made between the longitudinal and circumferential stress variations observed during the shield-driving and segment-assembly processes. Additionally, the time required for the grouting to reach its full curing strength was estimated, revealing its impact on the stress levels and range of the pipe segment. The findings of this study offer an enhanced understanding of the stress state and health condition of small-diameter shield tunnels, which can help in optimizing the design and construction process of tunnel segments, as well.
    Language English
    Publishing date 2023-09-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23198023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Spatial Responses of Ecosystem Service Trade-offs and Synergies to Impact Factors in Liaoning Province.

    Ren, Dong-Feng / Qiu, Ai-Ya / Cao, Ai-Hua / Zhang, Wen-Zhi / Xu, Ming-Wei

    Environmental management

    2023  

    Abstract: Global ecosystem services (ESs) are experiencing a significant decline, necessitating the development of robust environmental governance policies. To address the lack of integrated planning with heavy industry as the research object and a lack of ... ...

    Abstract Global ecosystem services (ESs) are experiencing a significant decline, necessitating the development of robust environmental governance policies. To address the lack of integrated planning with heavy industry as the research object and a lack of knowledge of ES trade-offs and synergies in China's ecological and environmental governance. In this study, the spatial and temporal variations of four ESs (water yield (WY), soil conservation (SC), carbon storage (CS), and habitat quality (HQ)) were determined in the study area of Liaoning Province. Explore the mechanisms that shape ecosystem service trade-offs and synergies and the factors that influence them. Spearman's correlation and difference analyses were proposed to determine the spatial and temporal distributions of trade-offs and synergistic relationships among ESs. In addition, we constructed a multiscale geo-weighted regression (MGWR) model to investigate driver spatial heterogeneity affecting trade-offs and synergies. The results revealed that (1) In the study area, ESs were on the rise in Liaoning Province. (2) Temporally, ESs were overwhelmingly dominated by synergies; at the spatial scale, ESs were dominated by trade-offs of varying degrees, with the area of synergy between WY and SC being the highest. (3) ESs demonstrated spatial heterogeneity in intensity and were more impacted by natural factors such as vegetation cover, elevation, and precipitation than by characteristics related to human activity. This study helps improve understanding of the interactions and dependencies among ESs and can provide a reference for ecological governance and improvements in Liaoning Province.
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1478932-2
    ISSN 1432-1009 ; 0364-152X
    ISSN (online) 1432-1009
    ISSN 0364-152X
    DOI 10.1007/s00267-023-01919-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Synthesis, crystal structure and magnetic properties of poly[[diaqua{μ

    Ma, Jie / Zhang, Wen-Zhi / Liu, Yong / Yi, Wen-Tao

    Acta crystallographica. Section E, Crystallographic communications

    2021  Volume 77, Issue Pt 9, Page(s) 939–943

    Abstract: The asymmetric unit of the polymeric title compound {[ ... ...

    Abstract The asymmetric unit of the polymeric title compound {[Co
    Language English
    Publishing date 2021-08-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 2056-9890 ; 1600-5368
    ISSN 2056-9890 ; 1600-5368
    DOI 10.1107/S2056989021008355
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Synthesis and crystal structure of

    Ma, Jie / Zhang, Wen-Zhi / Xiong, Jie / Yan, Chun-Yan

    Acta crystallographica. Section E, Crystallographic communications

    2021  Volume 77, Issue Pt 9, Page(s) 944–949

    Abstract: The title coordination polymer, {[ ... ...

    Abstract The title coordination polymer, {[Co
    Language English
    Publishing date 2021-08-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 2056-9890 ; 1600-5368
    ISSN 2056-9890 ; 1600-5368
    DOI 10.1107/S2056989021008343
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Role of ultrasound in the diagnosis of cervical tuberculous lymphadenitis in children.

    Yu, Tian-Zhuo / Zhang, Ying / Zhang, Wen-Zhi / Yang, Gao-Yi

    World journal of pediatrics : WJP

    2021  Volume 17, Issue 5, Page(s) 544–550

    Abstract: Background: To describe sonographic characteristics of cervical tuberculous lymphadenitis (CTBL) in children, clinical information, and sonograms of 348 lymph nodes (LNs) from 57 children with CTBL were retrospectively analyzed in this study.: Methods! ...

    Abstract Background: To describe sonographic characteristics of cervical tuberculous lymphadenitis (CTBL) in children, clinical information, and sonograms of 348 lymph nodes (LNs) from 57 children with CTBL were retrospectively analyzed in this study.
    Methods: We retrospectively reviewed the clinical data and sonograms of 348 LNs from 31 boys and 26 girls with CTBL, who were confirmed by pathology or laboratory examination, at the Hangzhou Red Cross Hospital between June 2014 and December 2020. The age of the children ranged from 1 to 14 years (average 7.1 ± 2.9 years).
    Results: Night sweats, fatigue and loss of appetite were the most common clinical symptoms observed in children with CTBL. Unilateral LN involvements were common. Occasionally, CTBL was found in healthy children with no symptoms. On sonography, the hilus was absent or unclear in all LNs. The short-to-long axis (S/L) ratio was ≥ 0.5, and the edges were unclear in most LNs. Other accompanying findings included necrosis (47.4%), an echogenic thin layer (36.8%), surrounding soft-tissue edema (38.5%), multiple intra-nodal strong echo (28.2%), sinus (22.7%) and abscess formation (6.9%). The Doppler ultrasound showed that the majority of vascularity patterns of CTBL were capsular or peripheral (33.3%).
    Conclusions: Ultrasound is a recommended examination method for children from different age groups with cervical lymphadenitis. The ultrasonic signs of hilus absence, S/L ratio ≥ 0.5, unclear edge, necrosis, echogenic thin layer, strong echoes and capsular or peripheral vascularity may aid in the diagnosis of cervical tuberculous lymphadenitis.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Diagnosis, Differential ; Female ; Humans ; Infant ; Lymph Nodes/diagnostic imaging ; Male ; Retrospective Studies ; Tuberculosis, Lymph Node/diagnostic imaging ; Ultrasonography
    Language English
    Publishing date 2021-09-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2236681-7
    ISSN 1867-0687 ; 1708-8569
    ISSN (online) 1867-0687
    ISSN 1708-8569
    DOI 10.1007/s12519-021-00453-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Diagnostic value of the dual-modal imaging radiomics model for subpleural pulmonary lesions.

    Tang, Wei / Zhang, Ying / Yu, Xiu-Lei / Zhang, Wen-Zhi / Chen, Pei-Jun / Wang, Ying / Zhang, Xu / Yang, Gao-Yi

    European journal of radiology

    2023  Volume 166, Page(s) 111000

    Abstract: Purpose: To investigate the clinical value of the radiomics model of grayscale ultrasound (GUS) and contrast-enhanced ultrasound (CEUS) to diagnosis subpleural pulmonary tuberculosis and nonpulmonary tuberculosis based on GUS and CEUS images.: Methods! ...

    Abstract Purpose: To investigate the clinical value of the radiomics model of grayscale ultrasound (GUS) and contrast-enhanced ultrasound (CEUS) to diagnosis subpleural pulmonary tuberculosis and nonpulmonary tuberculosis based on GUS and CEUS images.
    Methods: This study included 221 patients with 228 lesions diagnosed using the composite reference standard. The patients were randomly divided into training (n = 183) and test (n = 45) cohorts in an 8:2 ratio. The regions of interest of the GUS and CEUS images were manually segmented to extract the radiomic features. The GUS, CEUS and GUS+CEUS radiomics models were constructed via the multistep selection of highly correlated features. Receiver operating characteristic curves of the different models were plotted, and the area under the curve (AUC), accuracy, sensitivity, specificity, positive predictive value and negative predictive value (NPV) of the different models were compared.
    Results: Following Least Absolute Shrinkage and Selection Operator dimension reduction we selected 4, 9, and 11 features to construct the GUS, CEUS, and GUS+CEUS radiomics models, respectively. The AUC values of the three groups in the test cohort were 0.689, 0.748 and 0.779, respectively, and they did not differ significantly. In the test cohort, the GUS+CEUS radiomics model exhibited the highest AUC (0.779), accuracy (75.56%), and NPV (68.7%) of the three models.
    Conclusions: The GUS+CEUS radiomics model possesses good clinical value in diagnosing pulmonary tuberculosis.
    MeSH term(s) Humans ; Area Under Curve ; Retrospective Studies ; ROC Curve ; Tuberculosis, Pulmonary/diagnostic imaging ; Tuberculosis, Extrapulmonary/diagnostic imaging
    Language English
    Publishing date 2023-07-20
    Publishing country Ireland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2023.111000
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Elimination of antibiotic resistance genes in waste activated sludge by persulfate treatment during the process of sludge dewatering

    Duan, Wan-Jun / Gao, Jing-Feng / Zhang, Wen-Zhi / Wang, Yu-Wei / Liu, Jie

    Bioresource technology. 2020 Sept., v. 311

    2020  

    Abstract: Two sludge conditioning modes (nanoscale zero valent iron modified by Ginkgo biloba L. leaf (G-nZVI)/sodium persulfate (PS) conditioning with different ratios (1:0, 1:0.1, 1:1 and 1:10) and G-nZVI/PS conditioning with continuous addition) in reducing the ...

    Abstract Two sludge conditioning modes (nanoscale zero valent iron modified by Ginkgo biloba L. leaf (G-nZVI)/sodium persulfate (PS) conditioning with different ratios (1:0, 1:0.1, 1:1 and 1:10) and G-nZVI/PS conditioning with continuous addition) in reducing the specific resistance of filtration (SRF) and removing antibiotic resistant genes (ARGs) were investigated. After 3 min, the SRF values decreased in following order: 2.45 × 10⁸ m/kg (1:10) > 5.95 × 10⁶ m/kg (1:0.1) > 3.72 × 10⁶ m/kg (1:0) > 4.92 × 10⁵ m/kg (1:1). In the continuous addition (1:1), the SRF value decreased from 1.04 × 10⁸ m/kg to 6.47 × 10⁶ m/kg at 9 min. Removal efficiency of ARGs was 2–6 orders of magnitude and no regeneration of ARGs was observed in sludge and water phase. When treated samples were incubated for 36 h, dominant microflora was negatively correlated with ARGs. This study revealed persulfate treatment could achieve dewatering and remove ARGs, simultaneously.
    Keywords Ginkgo biloba ; activated sludge ; antibiotic resistance ; dewatering ; filtration ; iron ; microorganisms
    Language English
    Dates of publication 2020-09
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2020.123509
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  10. Article ; Online: Analysis of lumbar lateral instability on upright left and right bending radiographs in symptomatic patients with degenerative lumbar spondylolisthesis.

    Wang, Xin-Wen / Chen, Xi / Fu, Yang / Chen, Xiao / Zhang, Feng / Cai, Hai-Ping / Ge, Chang / Zhang, Wen-Zhi

    BMC musculoskeletal disorders

    2022  Volume 23, Issue 1, Page(s) 59

    Abstract: Background: To evaluate lumbar mobility in various positions using upright left and right bending radiographs in patients with degenerative lumbar spondylolisthesis (DLS), as well as to assess the impact of lateral instability on patient-reported ... ...

    Abstract Background: To evaluate lumbar mobility in various positions using upright left and right bending radiographs in patients with degenerative lumbar spondylolisthesis (DLS), as well as to assess the impact of lateral instability on patient-reported outcomes.
    Methods: This study retrospectively reviewed a consecutive series of patients with DLS between January 2019 and October 2020. The enrolled patients were divided into two groups: the lateral instability group (group L) and non-lateral instability group (group NL). Translational and angular motion in both sagittal and coronal planes and patient-reported outcomes were compared between the two groups.
    Results: There were 104 (59.8%) patients in group L and 70 (40.2%) patients in group NL, with an average age of 60.6 ± 7.8 years. Patients with a right bending posture in group L had a higher slip percentage (14.2 ± 7.4% vs 9.2 ± 3.2%, p = 0.01) and slip angle (6.3 ± 1.5° vs 2.2 ± 0.8°, p = 0.021). Compared with group NL, group L demonstrated significantly larger angular motion in the coronal plane (2.4 ± 1.3° vs 1.0 ± 0.7°, p = 0.008). Patients with lateral instability had worse preoperative back pain (6.1 ± 1.6 vs 2.7 ± 1.9, p = 0.01) and Oswestry Disability Index (ODI) scores (37.7 ± 5.5 vs 25.6 ± 2.6, p = 0.002). In terms of pain characteristics, group L was characterized by pain when getting out of a car, when rising from a chair, and when climbing stairs (all p values < 0.05).
    Conclusion: Lumbar lateral instability, that is, increased mobility in the coronal plane on lateral bending radiographs, translational and/or angular, correlates to more pronounced patient related symptoms in degenerative L4-5 spondylolisthesis. The existence of lumbar lateral instability leads to worse impacts on patient-reported outcomes when patients change their positions including getting out of a car, rising from a chair, and climbing stairs.
    MeSH term(s) Aged ; Humans ; Intervertebral Disc Degeneration/diagnostic imaging ; Lumbar Vertebrae/diagnostic imaging ; Lumbosacral Region ; Middle Aged ; Retrospective Studies ; Spondylolisthesis/diagnostic imaging
    Language English
    Publishing date 2022-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-022-05017-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top