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  1. Article: Empathy.

    Zhang, Wuyang / Hallock, Geoffrey G

    Archives of plastic surgery

    2022  Volume 49, Issue 1, Page(s) 3–4

    Language English
    Publishing date 2022-01-15
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2694943-X
    ISSN 2234-6171 ; 2234-6163
    ISSN (online) 2234-6171
    ISSN 2234-6163
    DOI 10.5999/aps.2021.02271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Empathy

    Zhang, Wuyang / Hallock, Geoffrey G.

    Archives of Plastic Surgery

    2022  Volume 49, Issue 01, Page(s) 3–4

    Language English
    Publishing date 2022-01-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2694943-X
    ISSN 2234-6171 ; 2234-6163 ; 2234-6171
    ISSN (online) 2234-6171
    ISSN 2234-6163 ; 2234-6171
    DOI 10.5999/aps.2021.02271
    Database Thieme publisher's database

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  3. Article: Recent advances in systemic therapy for hepatocellular carcinoma.

    Zhang, Huajun / Zhang, Wuyang / Jiang, Longying / Chen, Yongheng

    Biomarker research

    2022  Volume 10, Issue 1, Page(s) 3

    Abstract: Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially with conventional cytotoxic drugs, is usually ineffective. For more than a ...

    Abstract Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially with conventional cytotoxic drugs, is usually ineffective. For more than a decade, sorafenib has been the only systemic drug that has been proven to be clinically effective for treating advanced HCC. However, over the past three years, the rapid progress of molecular targeted therapies has dramatically changed the treatment landscape for advanced HCC. Immune checkpoint therapies are now being incorporated into HCC therapies, and their combination with molecular targeted therapy is emerging as a tool to enhance the immune response. In this review, we summarize the development and progress of molecular targeted agents and immunotherapies in HCC.
    Language English
    Publishing date 2022-01-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2699926-2
    ISSN 2050-7771
    ISSN 2050-7771
    DOI 10.1186/s40364-021-00350-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A systematic non-uniformity correction method for correlation-based ToF imaging.

    Wang, Xuanquan / Song, Ping / Zhang, Wuyang / Bai, Yunjian / Zheng, Zhaolin

    Optics express

    2022  Volume 30, Issue 2, Page(s) 1907–1924

    Abstract: Correlation-based time-of-flight (ToF) imaging enables a diverse range of applications for its high frame rate, high resolution and low cost. However, the non-uniformity of the sensor significantly affects the flat-field accuracy of the ToF imaging ... ...

    Abstract Correlation-based time-of-flight (ToF) imaging enables a diverse range of applications for its high frame rate, high resolution and low cost. However, the non-uniformity of the sensor significantly affects the flat-field accuracy of the ToF imaging system. In this paper, we analyze the sources of the non-uniformity and propose a systematic non-uniformity correction (NUC) method. The method utilizes the amplitude image, which can directly reflect the non-uniformity characteristics of the ToF sensor, to conduct NUC. Based on the established NUC system, the effectiveness and feasibility of the proposed NUC method are verified. Compared with the traditional methods, the RMSE was significantly reduced, while the SNR and PSNR were effectively improved. We believe this study provides new insights into the understanding of noise in the correlation-based ToF imaging system, and also provides effective references for the NUC of the three-dimensional measuring instruments.
    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.448029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Caregiving Time of Unpaid Family Caregivers Assisting Older Adults With Hearing Difficulty.

    Zhang, Wuyang / Powell, Danielle S / Garcia Morales, Emmanuel E / Deal, Jennifer A / Reed, Nicholas S

    Journal of aging and health

    2023  , Page(s) 8982643231208240

    Abstract: Objectives: ...

    Abstract Objectives:
    Language English
    Publishing date 2023-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1045392-1
    ISSN 1552-6887 ; 0898-2643
    ISSN (online) 1552-6887
    ISSN 0898-2643
    DOI 10.1177/08982643231208240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: An Improved Calibration Method for Photonic Mixer Device Solid-State Array Lidars Based on Electrical Analog Delay.

    Wang, Xuanquan / Song, Ping / Zhang, Wuyang

    Sensors (Basel, Switzerland)

    2020  Volume 20, Issue 24

    Abstract: As a typical application of indirect-time-of-flight (ToF) technology, photonic mixer device (PMD) solid-state array Lidar has gained rapid development in recent years. With the advantages of high resolution, frame rate and accuracy, the equipment is ... ...

    Abstract As a typical application of indirect-time-of-flight (ToF) technology, photonic mixer device (PMD) solid-state array Lidar has gained rapid development in recent years. With the advantages of high resolution, frame rate and accuracy, the equipment is widely used in target recognition, simultaneous localization and mapping (SLAM), industrial inspection, etc. The PMD Lidar is vulnerable to several factors such as ambient light, temperature and the target feature. To eliminate the impact of such factors, a proper calibration is needed. However, the conventional calibration methods need to change several distances in large areas, which result in low efficiency and low accuracy. To address the problems, this paper presents an improved calibration method based on electrical analog delay. The method firstly eliminates the lens distortion using a self-adaptive interpolation algorithm, meanwhile it calibrates the grayscale image using an integral time simulating based method. Then, the grayscale image is used to estimate the parameters of ambient light compensation in depth calibration. Finally, by combining four types of compensation, the method effectively improves the performance of depth calibration. Through several experiments, the proposed method is more adaptive to multiscenes with targets of different reflectivities, which significantly improves the ranging accuracy and adaptability of PMD Lidar.
    Language English
    Publishing date 2020-12-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s20247329
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Modeling and simulations of a three-dimensional ghost imaging method with differential correlation sampling.

    Liu, Bohu / Song, Ping / Zhai, Yayu / Wang, Xuanquan / Zhang, Wuyang

    Optics express

    2021  Volume 29, Issue 23, Page(s) 38879–38893

    Abstract: The quality of depth maps acquired by a time-of-flight three-dimensional ghost imaging (3DGI) system is limited by dynamic ambient light and electrical noise. We developed a novel method that integrates the differential-correlation-sampling (DCS) method ... ...

    Abstract The quality of depth maps acquired by a time-of-flight three-dimensional ghost imaging (3DGI) system is limited by dynamic ambient light and electrical noise. We developed a novel method that integrates the differential-correlation-sampling (DCS) method and a modulated continuous-wave laser source to realize the 3DGI and reduce the noise influence. The simulation results for the proposed method, DCS-3DGI, verify its feasibility. The analysis of mean-square-error, peak signal-to-noise ratio, structural similarity index measure, and edge preservation index demonstrates a superior anti-interference performance than conventional 3DGI methods.
    Language English
    Publishing date 2021-10-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.442889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Fast lightweight framework for time-of-flight super-resolution based on block compressed sensing.

    Zhang, Wuyang / Song, Ping / Wang, Xuanquan / Zheng, Zhaolin / Bai, Yunjian / Geng, Haocheng

    Optics express

    2022  Volume 30, Issue 9, Page(s) 15096–15112

    Abstract: Compressive time-of-flight (ToF) imaging for super-resolution (SR) has tremendous development potential owing to its cost-effectiveness and simplicity. However, existing compressive ToF methods are difficult to apply in practical situations because of ... ...

    Abstract Compressive time-of-flight (ToF) imaging for super-resolution (SR) has tremendous development potential owing to its cost-effectiveness and simplicity. However, existing compressive ToF methods are difficult to apply in practical situations because of their low efficiency and high data storage requirements. In this paper, we propose a fast and lightweight compressive ToF framework for SR. The block compressed sensing method, which shows distinct characteristics of high efficiency and low implementation cost, is introduced into the SR image acquisition and data transmission processes. Based on this framework, we establish a prototype system and verify it experimentally. Compared with existing compressive ToF systems, both the reconstruction time and data storage requirements are significantly decreased. We believe that this study provides a development direction for compressive ToF imaging and effective guidance for researchers realizing highly efficient and lightweight SR image reconstruction.
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.456196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The association of hearing loss with frailty among community-dwelling older adults: findings from the National Health and Aging Trends Study.

    Assi, Sahar / Zhang, Wuyang / Carey, John P / Deal, Jennifer A / Huang, Alison / Oh, Esther S / Martinez-Amezcua, Pablo / Reed, Nicholas S

    BMC geriatrics

    2023  Volume 23, Issue 1, Page(s) 754

    Abstract: Background: The identification of modifiable risk factors is crucial for the prevention and/or reversal of frailty, which is associated with significant morbidity and mortality. Hearing loss affects two-thirds of older adults in the United States (U.S.) ...

    Abstract Background: The identification of modifiable risk factors is crucial for the prevention and/or reversal of frailty, which is associated with significant morbidity and mortality. Hearing loss affects two-thirds of older adults in the United States (U.S.) and is associated with physical and cognitive decline which may increase frailty risk. We investigated the association of hearing loss and hearing aid use with frailty and pre-frailty in a nationally representative sample of older adults in the U.S.
    Methods: Cross-sectional analysis of the National Health and Aging Trends Study (2021 round). The better-hearing ear pure-tone average (BPTA) at speech-frequencies (0.5-4 kHz) was modeled continuously (per 10 dB) and categorically (no ≤ 25 dB, mild 26-40 dB, moderate or greater > 40 dB hearing loss). Hearing aid use was self-reported. The physical frailty phenotype (frail, pre-frail, robust) was determined based on Fried criteria: unintentional weight loss, exhaustion, low physical activity, weakness, slow walking speed. We used multinomial multivariable regression adjusted for sociodemographic and health characteristics (odds ratios [95% Confidence Intervals]).
    Results: Among 2,361 participants (mean age = 81 years, 56% female, 19% Black), 860 (36%) had mild and 864 (37%) had moderate or greater hearing loss. Worse hearing was associated with greater odds of being frail versus robust (OR = 1.20 [1.05-1.38] per 10 dB difference). Categorically, moderate or greater hearing loss was associated with greater odds of being frail (OR = 1.84 [1.01-3.08]) and pre-frail (OR = 1.46 [1.01-2.10]) versus robust. Among 1,724 participants with hearing loss, compared to hearing aid users (N = 522), nonusers had greater odds of being frail (OR = 2.54 [1.54-4.18]) and pre-frail (OR = 1.51 [1.05-2.17]) versus robust, and frail versus pre-frail (OR = 1.68 [1.04-2.72]).
    Conclusions: In a nationally representative sample of older adults in the U.S., using gold-standard hearing measures and a validated frailty phenotype, hearing loss and lack of hearing aid use was cross-sectionally associated with frailty and pre-frailty. Future longitudinal studies are needed to establish if hearing loss is a risk factor for frailty, which may have significant clinical importance.
    MeSH term(s) Humans ; Female ; Aged ; Aged, 80 and over ; Male ; Frailty/diagnosis ; Frailty/epidemiology ; Frail Elderly/psychology ; Independent Living ; Cross-Sectional Studies ; Geriatric Assessment ; Aging ; Hearing Loss/diagnosis ; Hearing Loss/epidemiology
    Language English
    Publishing date 2023-11-17
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-023-04465-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Factors and potential treatments of cough after pulmonary resection: A systematic review.

    Li, Xin / Li, Xizhe / Zhang, Wuyang / Liu, Qi / Gao, Yang / Chang, Ruimin / Zhang, Chunfang

    Asian journal of surgery

    2021  Volume 44, Issue 8, Page(s) 1029–1036

    Abstract: Cough is a common complication following pulmonary resection. Persistent and severe cough after pulmonary resection can cause significant impairments in quality of life among postoperative patients. Complications of cough can be life-threatening. To ... ...

    Abstract Cough is a common complication following pulmonary resection. Persistent and severe cough after pulmonary resection can cause significant impairments in quality of life among postoperative patients. Complications of cough can be life-threatening. To improve patients' probability and quality of life, factors that induce cough after pulmonary resection (CAP) and potential treatments should be explored and summarized. Previous studies have identified various factors related to CAP. However, those factors have not been categorized and analyzed in a sensible manner. Here, we summarized the different factors and classified them into four groups. Potential therapies might be developed to selectively target different factors that affect CAP. However, the exact mechanism underlying CAP remains unknown, making it difficult to treat and manage CAP. In this review, we summarized the latest studies in our understanding of the factors related to CAP and potential treatments targeting those factors. This review can help understand the mechanism of CAP and develop efficient therapies and management.
    MeSH term(s) Cough/etiology ; Humans ; Quality of Life
    Language English
    Publishing date 2021-02-17
    Publishing country China
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2021.01.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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