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  1. Article: Editorial: Microbiome-gut-brain axis crosstalk and clinical outcomes.

    Zhang, Xiaojie

    Frontiers in nutrition

    2024  Volume 11, Page(s) 1358659

    Language English
    Publishing date 2024-02-12
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2024.1358659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Atypical Takotsubo Cardiomyopathy With Persistent Left Ventricular Aneurysm After Cardiac Surgery.

    Zhang, Xiaojie

    The heart surgery forum

    2021  Volume 24, Issue 3, Page(s) E442–E444

    Abstract: A 57-year-old man was admitted to the hospital because of severe mitral regurgitation. Minimally invasive mitral valvuloplasty was performed. Six months after surgery, he presented with discomfort. Urgent coronary angiography showed a normal coronary ... ...

    Abstract A 57-year-old man was admitted to the hospital because of severe mitral regurgitation. Minimally invasive mitral valvuloplasty was performed. Six months after surgery, he presented with discomfort. Urgent coronary angiography showed a normal coronary artery and large left ventricular aneurysm. After atypical Takotsubo cardiomyopathy was diagnosed, his clinical symptoms and heart function were improved with medication for his persistent left ventricular aneurysm. After 24 hours, Hotler showed a lethal ventricular arrhythmia. Surgical treatment was recommended and refused. After four years of observation, he died of asystole. Takotsubo cardiomyopathy is considered a severe complication after surgery. The prognosis is very poor if it has catastrophic complications.
    MeSH term(s) Balloon Valvuloplasty/adverse effects ; Coronary Angiography ; Echocardiography ; Heart Aneurysm/diagnosis ; Heart Aneurysm/etiology ; Heart Ventricles ; Humans ; Male ; Middle Aged ; Mitral Valve Insufficiency/surgery ; Postoperative Complications ; Prognosis ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/etiology
    Language English
    Publishing date 2021-05-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2069188-9
    ISSN 1522-6662 ; 1098-3511
    ISSN (online) 1522-6662
    ISSN 1098-3511
    DOI 10.1532/hsf.3705
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5745: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Molecular-Level Kinetic Model for Light Hydrocarbon Steam Cracking Based on the SU-BEM Framework.

    Xu, Dongyu / Zhang, Xiaojie / Chen, Zhengyu / Zhang, Linzhou

    ACS omega

    2024  Volume 9, Issue 13, Page(s) 14849–14859

    Abstract: In this work, a molecular-level kinetic model of ethane/propane steam cracking was developed by using a hybrid structural unit-bond electron matrix framework. The molecular-level simulation was conducted, creating a detailed feedstock composition, ... ...

    Abstract In this work, a molecular-level kinetic model of ethane/propane steam cracking was developed by using a hybrid structural unit-bond electron matrix framework. The molecular-level simulation was conducted, creating a detailed feedstock composition, formulating the reaction rules, and automating the generation and visualization of reaction networks. Ordinary differential equations were automatically generated based on the Arrhenius equation, while the kinetic parameters were reduced via linear free energy relations (LFERs). Furthermore, proper mathematical models for mass transfer, heat transfer, and momentum transfer within the cracking furnace were integrated into the molecular-level kinetic model, enabling the simultaneous calculation of the transfer process and chemical kinetics in steam cracking. The model was validated by its precise prediction of product yields, outlet pressure, and outlet temperature, which were collected from an industrial gas-cracking furnace.
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c07749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cytotoxic ent-abietane diterpenoids from the leaves of Croton lachnocarpus Benth

    Wang, Wei / Zhang, Xiao-Jie

    Journal of Asian Natural Products Research. 2023 Apr. 3, v. 25, no. 4 p.309-315

    2023  

    Abstract: A phytochemical investigation on the 90% ethanol extract of the leaves of Croton lachnocarpus Benth. led to three new ent-abietane diterpenoids, 7β,15-dihydroxy-ent-abieta-8,11,13-trien-3-one (1), 2β,15-dihydroxy-ent-abieta-8,11,13-triene (2), and 7β,13α, ...

    Abstract A phytochemical investigation on the 90% ethanol extract of the leaves of Croton lachnocarpus Benth. led to three new ent-abietane diterpenoids, 7β,15-dihydroxy-ent-abieta-8,11,13-trien-3-one (1), 2β,15-dihydroxy-ent-abieta-8,11,13-triene (2), and 7β,13α,15-trihydroxy-ent-abieta-8(14)-en-3-one (3). Structural elucidation of all the compounds were performed by spectral methods such as 1 D and 2 D (¹H- ¹H COSY, HMQC, NOESY and HMBC) NMR spectroscopy, in addition to electronic circular dichroism (ECD) spectra. The isolated compounds were tested in vitro for cytotoxic activity against 6 tumor cell lines. As a result, compound 3 exhibited some cytotoxicities against all the tested tumor cell lines with IC₅₀ value less than 30 μM.
    Keywords Croton ; circular dichroism spectroscopy ; cytotoxicity ; diterpenoids ; ethanol ; neoplasm cells ; nuclear magnetic resonance spectroscopy ; phytochemicals ; research ; Croton lachnocarpus ; Euphorbiaceae ; ent-abietane diterpenoids ; cytotoxic activity
    Language English
    Dates of publication 2023-0403
    Size p. 309-315.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2077926-4
    ISSN 1477-2213 ; 1028-6020
    ISSN (online) 1477-2213
    ISSN 1028-6020
    DOI 10.1080/10286020.2022.2090346
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Factors Contributing to Citizens' Participation in COVID-19 Prevention and Control in China: An Integrated Model Based on Theory of Planned Behavior, Norm Activation Model, and Political Opportunity Structure Theory.

    Zhang, Xiaojie / Wang, Lili

    International journal of environmental research and public health

    2022  Volume 19, Issue 23

    Abstract: Chinese citizens' participation in COVID-19 prevention and control has made great contributions to the successful fight against the pandemic. The factors that have impacted citizens' participation have rarely been reported based on both social- ... ...

    Abstract Chinese citizens' participation in COVID-19 prevention and control has made great contributions to the successful fight against the pandemic. The factors that have impacted citizens' participation have rarely been reported based on both social-psychological and political environmental theories. This paper presented a study to explore the determinants of Chinese citizens' participation in COVID-19 prevention and control based on a combined model of the theory of planned behavior, the norm activation model, and political opportunity structure theory. A dataset involving 463 respondents from Harbin in northeast China was acquired and analyzed. The results showed that the comprehensive model explained 62.9% of the total variance in citizens' participation behavior. The openness to public participation not only significantly directly influenced citizens' participation but also indirectly affected participation behaviors through attitude and perceived behavioral control, both of which were important mediators and had the greatest overall impacts. The awareness of consequences and subjective norms were crucial antecedents to the activation of other influencing factors. Personal norms indirectly affected participation behavior through the mediation of attitude. The empirical results showed the comprehensiveness, effectiveness, and high explanatory power of the postulated model. The study also provides both new theoretical perspectives for explaining public participation and useful practical implications for future policy development in promoting citizens' participation in public health emergency management.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; Theory of Planned Behavior ; Community Participation/methods ; Pandemics/prevention & control ; Attitude
    Language English
    Publishing date 2022-11-27
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph192315794
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  6. Article ; Online: Cytotoxic ent-abietane diterpenoids from the leaves of

    Wang, Wei / Zhang, Xiao-Jie

    Journal of Asian natural products research

    2022  Volume 25, Issue 4, Page(s) 309–315

    Abstract: A phytochemical investigation on the 90% ethanol extract of the leaves ... ...

    Abstract A phytochemical investigation on the 90% ethanol extract of the leaves of
    MeSH term(s) Abietanes/chemistry ; Croton/chemistry ; Antineoplastic Agents ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; Cell Line, Tumor ; Diterpenes/chemistry ; Molecular Structure
    Chemical Substances Abietanes ; Antineoplastic Agents ; Plant Extracts ; Diterpenes
    Language English
    Publishing date 2022-07-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077926-4
    ISSN 1477-2213 ; 1028-6020
    ISSN (online) 1477-2213
    ISSN 1028-6020
    DOI 10.1080/10286020.2022.2090346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nanomedicine targeted anti-inflammatory therapy to deal with the 'crux' of rheumatoid arthritis.

    An, Min / Zhang, Juntao / Zhang, Xiaojie / Zhao, Yumeng / Liu, Yanhua

    Journal of drug targeting

    2024  Volume 32, Issue 4, Page(s) 381–392

    Abstract: Rheumatoid arthritis is a chronic and complex autoimmune disease that is marked by an inflammatory response, synovial hyperplasia, vascularisation, fascial formation, cartilage and bone destruction, which can lead to joint deformity and even loss of ... ...

    Abstract Rheumatoid arthritis is a chronic and complex autoimmune disease that is marked by an inflammatory response, synovial hyperplasia, vascularisation, fascial formation, cartilage and bone destruction, which can lead to joint deformity and even loss of function, ultimately affecting a person's health and quality of life. Although the pathogenesis of RA is unclear, growing evidence suggests that inflammation-associated cells infiltrate joints, causing tissue damage, inflammation and pain. This disruption in the balance between host tolerance and immune homeostasis the progression of RA. Existing drug therapy and surgical treatments for RA are unable to completely cure the disease or reverse its accelerated progression. Therefore, the design and development of an appropriate and effective drug delivery system will substantially improve the therapeutic effect. In this review, by describing the inflammatory microenvironment of rheumatoid arthritis and the associated inflammatory cells, the progress of targeting strategies and applications of nanotechnology in the disease is summarised, which will be helpful in providing new ideas for the subsequent treatment of rheumatoid arthritis.
    MeSH term(s) Humans ; Nanomedicine ; Quality of Life ; Arthritis, Rheumatoid/drug therapy ; Inflammation/drug therapy ; Inflammation/pathology ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use
    Chemical Substances Anti-Inflammatory Agents
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1187110-6
    ISSN 1029-2330 ; 1061-186X
    ISSN (online) 1029-2330
    ISSN 1061-186X
    DOI 10.1080/1061186X.2024.2315475
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4481: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Nano-medicine therapy reprogramming metabolic network of tumour microenvironment: new opportunity for cancer therapies.

    Zhang, Xiaojie / An, Min / Zhang, Juntao / Zhao, Yumeng / Liu, Yanhua

    Journal of drug targeting

    2024  Volume 32, Issue 3, Page(s) 241–257

    Abstract: Metabolic heterogeneity is one of the characteristics of tumour cells. In order to adapt to the tumour microenvironment of hypoxia, acidity and nutritional deficiency, tumour cells have undergone extensive metabolic reprogramming. Metabolites involved in ...

    Abstract Metabolic heterogeneity is one of the characteristics of tumour cells. In order to adapt to the tumour microenvironment of hypoxia, acidity and nutritional deficiency, tumour cells have undergone extensive metabolic reprogramming. Metabolites involved in tumour cell metabolism are also very different from normal cells, such as a large number of lactate and adenosine. Metabolites play an important role in regulating the whole tumour microenvironment. Taking metabolites as the target, it aims to change the metabolic pattern of tumour cells again, destroy the energy balance it maintains, activate the immune system, and finally kill tumour cells. In this paper, the regulatory effects of metabolites such as lactate, glutamine, arginine, tryptophan, fatty acids and adenosine were reviewed, and the related targeting strategies of nano-medicines were summarised, and the future therapeutic strategies of nano-drugs were discussed. The abnormality of tumour metabolites caused by tumour metabolic remodelling not only changes the energy and material supply of tumour, but also participates in the regulation of tumour-related signal pathways, which plays an important role in the survival, proliferation, invasion and metastasis of tumour cells. Regulating the availability of local metabolites is a new aspect that affects tumour progress. (The graphical abstract is by Figdraw).
    MeSH term(s) Humans ; Neoplasms/metabolism ; Energy Metabolism ; Metabolic Networks and Pathways ; Lactates/pharmacology ; Lactates/therapeutic use ; Adenosine ; Tumor Microenvironment
    Chemical Substances Lactates ; Adenosine (K72T3FS567)
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1187110-6
    ISSN 1029-2330 ; 1061-186X
    ISSN (online) 1029-2330
    ISSN 1061-186X
    DOI 10.1080/1061186X.2024.2309565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4481: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Heterogeneous reaction of NO

    Gao, Xiaoyan / Zhu, Menglong / Long, Yu / Zhang, Xiaojie / Min, Dandan

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2024  Volume 314, Page(s) 124205

    Abstract: Heterogeneous reactions on mineral dust surfaces are increasingly considered important in the removal of gaseous pollutants and the formation of secondary aerosols. Although the heterogeneous reaction of ... ...

    Abstract Heterogeneous reactions on mineral dust surfaces are increasingly considered important in the removal of gaseous pollutants and the formation of secondary aerosols. Although the heterogeneous reaction of NO
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2024.124205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 51/98: Show issues
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    924/340: Show issues

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  10. Article ; Online: Evaluating Community Capability to Prevent and Control COVID-19 Pandemic in Shenyang, China: An Empirical Study Based on a Modified Framework of Community Readiness Model.

    Zhang, Xiaojie / Liu, Xiaoyu / Wang, Lili

    International journal of environmental research and public health

    2023  Volume 20, Issue 5

    Abstract: Community plays a crucial role in the successful prevention and control of the COVID-19 pandemic in China. However, evaluation of community capability to fight against COVID-19 is rarely reported. The present study provides a first attempt to assess ... ...

    Abstract Community plays a crucial role in the successful prevention and control of the COVID-19 pandemic in China. However, evaluation of community capability to fight against COVID-19 is rarely reported. The present study provides a first attempt to assess community capability to combat COVID-19 in Shenyang, the capital city of Liaoning province in Northeast China, based on a modified framework of a community readiness model. We conducted semi-structured interviews with ninety key informants from fifteen randomly selected urban communities to collect the data. The empirical results indicate that the overall level of community capability for epidemic prevention and control in Shenyang was at the stage of preparation. The specific levels of the fifteen communities ranged from the stages of preplanning to preparation to initiation. Concerning the level of each dimension, community knowledge about the issue, leadership, and community attachment exhibited significant disparities between communities, while there were slight differences among communities on community efforts, community knowledge of efforts, and community resources. In addition, leadership demonstrated the highest overall level among all the six dimensions, followed by community attachment and community knowledge of efforts. Community resources displayed the lowest level, followed by community efforts. This study not only extends the application of the modified community readiness model to evaluate community capability of epidemic prevention in the Chinese community context, but also offers practical implications for enhancing Chinese communities' capabilities to deal with various future public health emergencies.
    MeSH term(s) Humans ; Pandemics ; COVID-19 ; Empirical Research ; Leadership ; Public Health
    Language English
    Publishing date 2023-02-23
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20053996
    Database MEDical Literature Analysis and Retrieval System OnLINE

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