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  1. Article ; Online: Uncertainty-driven mixture convolution and transformer network for remote sensing image super-resolution.

    Zhang, Xiaomin

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 9435

    Abstract: Recently, convolutional neural networks (CNNs) and Transformer-based Networks have exhibited remarkable prowess in the realm of remote sensing image super-resolution (RSISR), delivering promising results in the field. Nevertheless, the effective fusion ... ...

    Abstract Recently, convolutional neural networks (CNNs) and Transformer-based Networks have exhibited remarkable prowess in the realm of remote sensing image super-resolution (RSISR), delivering promising results in the field. Nevertheless, the effective fusion of the inductive bias inherent in CNNs and the long-range modeling capabilities encapsulated within the Transformer architecture remains a relatively uncharted terrain in the context of RSISR endeavors. Accordingly, we propose an uncertainty-driven mixture convolution and transformer network (UMCTN) to earn a performance promotion. Specifically, to acquire multi-scale and hierarchical features, UMCTN adopts a U-shape architecture. Utilizing the dual-view aggregation block (DAB) based residual dual-view aggregation group (RDAG) in both encoder and decoder, we solely introduce a pioneering dense-sparse transformer group (DSTG) into the latent layer. This design effectively eradicates the considerable quadratic complexity inherent in vanilla Transformer structures. Moreover, we introduce a novel uncertainty-driven Loss (UDL) to steer the network's attention towards pixels exhibiting significant variance. The primary objective is to elevate the reconstruction quality specifically in texture and edge regions. Experimental outcomes on the UCMerced LandUse and AID datasets unequivocally affirm that UMCTN achieves state-of-the-art performance in comparison to presently prevailing methodologies.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-59384-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Efficient absorption of CO2 by protic-ionic-liquid based deep eutectic solvents.

    Wen, Shuyue / Zhang, Xiaomin / Wu, Youting

    Chemistry, an Asian journal

    2024  , Page(s) e202400234

    Abstract: Carbon capture, utilization, and storage (CCUS) are among the key technologies to achieve large-scale carbon emission reduction globally. Deep eutectic solvents (DESs) are considered as designable solvents, which has attracted intensive attention for CO2 ...

    Abstract Carbon capture, utilization, and storage (CCUS) are among the key technologies to achieve large-scale carbon emission reduction globally. Deep eutectic solvents (DESs) are considered as designable solvents, which has attracted intensive attention for CO2 capture. Here, a series of binary DESs are synthesized through one-step mixing with the starting materials of protic ionic liquid (PIL) and amine. The eutectic behavior was investigated by measuring the melting point of PILs and amine. The saturated vapor of these DESs and industrial MDEA solution were measured and compared. These DESs are investigated to have high absorption capacity (0.1 g·g-1 at 1.0 bar and 25ºC), superior apparent absorption rate constant (0.381 min-1 vs 0.012 min-1 of MDEA-30%H2O), moderate interaction with CO2 (the enthalpy change is as low as -34.8 kJ·mol-1). The absorption mechanism is also investigated by NMR analysis. Eight absorption/desorption regeneration experiments are carried out to show their reversibility. Considering the advantages, including convenience of synthesis, large absorption capacity, fast absorption rate, and moderate interaction energy as well as good regeneration, these DESs are believed to be as potential CO2 absorbent in practical applications.
    Language English
    Publishing date 2024-04-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202400234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Involvement of Fgf2-mediated tau protein phosphorylation in cognitive deficits induced by sevoflurane in aged rats.

    Xie, Xin / Zhang, Xiaomin / Li, Songze / Du, Wei

    Molecular medicine (Cambridge, Mass.)

    2024  Volume 30, Issue 1, Page(s) 39

    Abstract: Objective: Anesthetics have been linked to cognitive alterations, particularly in the elderly. The current research delineates how Fibroblast Growth Factor 2 (Fgf2) modulates tau protein phosphorylation, contributing to cognitive impairments in aged ... ...

    Abstract Objective: Anesthetics have been linked to cognitive alterations, particularly in the elderly. The current research delineates how Fibroblast Growth Factor 2 (Fgf2) modulates tau protein phosphorylation, contributing to cognitive impairments in aged rats upon sevoflurane administration.
    Methods: Rats aged 3, 12, and 18 months were subjected to a 2.5% sevoflurane exposure to form a neurotoxicity model. Cognitive performance was gauged, and the GEO database was employed to identify differentially expressed genes (DEGs) in the 18-month-old cohort post sevoflurane exposure. Bioinformatics tools, inclusive of STRING and GeneCards, facilitated detailed analysis. Experimental validations, both in vivo and in vitro, examined Fgf2's effect on tau phosphorylation.
    Results: Sevoflurane notably altered cognitive behavior in older rats. Out of 128 DEGs discerned, Fgf2 stood out as instrumental in regulating tau protein phosphorylation. Sevoflurane exposure spiked Fgf2 expression in cortical neurons, intensifying tau phosphorylation via the PI3K/AKT/Gsk3b trajectory. Diminishing Fgf2 expression correspondingly curtailed tau phosphorylation, neurofibrillary tangles, and enhanced cognitive capacities in aged rats.
    Conclusion: Sevoflurane elicits a surge in Fgf2 expression in aging rats, directing tau protein phosphorylation through the PI3K/AKT/Gsk3b route, instigating cognitive aberrations.
    MeSH term(s) Aged ; Animals ; Humans ; Infant ; Rats ; Anesthetics, Inhalation/adverse effects ; Anesthetics, Inhalation/metabolism ; Cognition ; Cognitive Dysfunction/chemically induced ; Cognitive Dysfunction/metabolism ; Hippocampus/metabolism ; Methyl Ethers/pharmacology ; Methyl Ethers/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Sevoflurane/metabolism ; Sevoflurane/pharmacology ; tau Proteins/metabolism ; Fibroblast Growth Factor 2/metabolism
    Chemical Substances Anesthetics, Inhalation ; Methyl Ethers ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Sevoflurane (38LVP0K73A) ; tau Proteins ; Fibroblast Growth Factor 2 (103107-01-3)
    Language English
    Publishing date 2024-03-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1283676-x
    ISSN 1528-3658 ; 1076-1551
    ISSN (online) 1528-3658
    ISSN 1076-1551
    DOI 10.1186/s10020-024-00784-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Neural Mechanism Underlying Differentiated In-Group Versus Out-Group Face Recognition and Memory, Identification, Empathy and Pro-social Behavior: Evidence from fMRI and ERP Studies.

    Peng, Kaizhen / Tan, Lili / Zhang, Xiaomin

    Journal of integrative neuroscience

    2024  Volume 23, Issue 3, Page(s) 48

    Abstract: In the context of perceiving individuals within and outside of social groups, there are distinct cognitive processes and mechanisms in the brain. Extensive research in recent years has delved into the neural mechanisms that underlie differences in how we ...

    Abstract In the context of perceiving individuals within and outside of social groups, there are distinct cognitive processes and mechanisms in the brain. Extensive research in recent years has delved into the neural mechanisms that underlie differences in how we perceive individuals from different social groups. To gain a deeper understanding of these neural mechanisms, we present a comprehensive review from the perspectives of facial recognition and memory, intergroup identification, empathy, and pro-social behavior. Specifically, we focus on studies that utilize functional magnetic resonance imaging (fMRI) and event-related potential (ERP) techniques to explore the relationship between brain regions and behavior. Findings from fMRI studies reveal that the brain regions associated with intergroup differentiation in perception and behavior do not operate independently but instead exhibit dynamic interactions. Similarly, ERP studies indicate that the amplitude of neural responses shows various combinations in relation to perception and behavior.
    MeSH term(s) Humans ; Empathy ; Facial Recognition ; Magnetic Resonance Imaging ; Brain/physiology ; Evoked Potentials/physiology ; Brain Mapping ; Social Behavior
    Language English
    Publishing date 2024-03-25
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2136427-8
    ISSN 0219-6352
    ISSN 0219-6352
    DOI 10.31083/j.jin2303048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The relationship between exercise commitment and college students' exercise adherence: The chained mediating role of exercise atmosphere and exercise self-efficacy.

    Li, Yue / Xu, Jingchen / Zhang, Xiaomin / Chen, Gaopeng

    Acta psychologica

    2024  Volume 246, Page(s) 104253

    Abstract: Objective: This study aims to explore the mechanisms underlying exercise commitment, exercise atmosphere, exercise self-efficacy, and exercise adherence among college students, as well as the impact of gender differences on these mechanisms.: Methods!# ...

    Abstract Objective: This study aims to explore the mechanisms underlying exercise commitment, exercise atmosphere, exercise self-efficacy, and exercise adherence among college students, as well as the impact of gender differences on these mechanisms.
    Methods: Using a stratified cluster sampling method, 984 college students (aged 19.74 ± 1.25 years) from six universities in Anhui, Shandong, and Shaanxi provinces were randomly selected, with 403 male students and 581 female students. They had completed the Exercise Commitment Scale (ECC), Physical Exercise Atmosphere Scale (PEAS), Exercise Self-Efficacy Scale (ESES), and Exercise Adherence Scale (EPS). The study variables were analyzed in sequence for reliability and validity, correlation analysis, regression analysis, structural equation model testing, and bias-corrected percentile Bootstrap testing using SPSS 23.0 software and Hayes' (2013) Process plug-in.
    Results: Exercise commitment significantly positively predicted exercise adherence (β = 0.796, p < 0.01), exercise commitment significantly positively predicted exercise environment and exercise self-efficacy (β = 0.645, p < 0.01, β = 0.356, p < 0.01), exercise environment significantly positively predicted exercise self-efficacy and exercise adherence (β = 0.344, p < 0.01, β = 0.144, p < 0.01), and exercise self-efficacy significantly positively predicted exercise adherence (β = 0.934, p < 0.01). The mediating role of exercise environment in the relationship between exercise commitment and exercise adherence does not exist in male college students, while it exists in female college students.
    Conclusions: Exercise atmosphere and exercise self-efficacy play a mediating role between exercise commitment and exercise adherence, with a total mediating effect value of 0.796. This study indicates that exercise commitment not only directly predicts exercise adherence, but also indirectly predicts exercise adherence through the chained mediating effects of exercise atmosphere and exercise self-efficacy. The above-mentioned mediating effect exists in female college students, while some mediating effects do not exist in male college students, thus gender has a significant impact on this mediating effect.
    Language English
    Publishing date 2024-04-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1480049-4
    ISSN 1873-6297 ; 0001-6918
    ISSN (online) 1873-6297
    ISSN 0001-6918
    DOI 10.1016/j.actpsy.2024.104253
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online ; Thesis: In-vitro effects of noradrenaline and lipopolysaccharide on mitochondrial function of different immortalised cell types

    Zhang, Xiaomin [Verfasser]

    2022  

    Author's details Xiaomin Zhang
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Universität Ulm
    Publishing place Ulm
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Article: What Research Has Been Conducted on Procrastination? Evidence From a Systematical Bibliometric Analysis.

    Yan, Bo / Zhang, Xiaomin

    Frontiers in psychology

    2022  Volume 13, Page(s) 809044

    Abstract: Procrastination is generally perceived as a common behavioral tendency, and there are a growing number of literatures to discuss this complex phenomenon. To elucidate the overall perspective and keep abreast of emerging trends in procrastination research, ...

    Abstract Procrastination is generally perceived as a common behavioral tendency, and there are a growing number of literatures to discuss this complex phenomenon. To elucidate the overall perspective and keep abreast of emerging trends in procrastination research, this article presents a bibliometric analysis that investigates the panorama of overviews and intellectual structures of related research on procrastination. Using the Web of Science Database, we collected 1,635 articles published between 1990 and 2020 with a topic search on "procrastination" and created diverse research maps using CiteSpace and VOS viewer. Bibliometric analysis in our research consists of category distribution, keyword co-occurrence networks, main cluster analysis, betweenness centrality analysis, burst detection analysis, and structure variation analysis. We find that most research has focused on students' samples and has discussed the definition, classification, antecedents, consequences and interventions to procrastination, whereas procrastination in diverse contexts and groups remains to be investigated. Regarding the antecedents and consequences, research has mainly been about the relationship between procrastination and personality differences, such as the five-factor model, temperament, character, emotional intelligence, and impulsivity, but functions of external factors such as task characteristics and environmental conditions to procrastination have drawn scant attention. To identify the nature and characteristics of this behavior, randomized controlled trials are usually adopted in designing empirical research. However, the predominant use of self-reported data collection and for a certain point in time rather than longitudinal designs has limited the validation of some conclusions. Notably, there have been novel findings through burst detection analysis and structure variation analysis. Certain research themes have gained extraordinary attention in a short time period, have evolved progressively during the time span from 1990 to 2020, and involve the antecedents of procrastination in a temporal context, theoretical perspectives, research methods, and typical images of procrastinators. And emerging research themes that have been investigated include bedtime procrastination, failure of social media self-control, and clinical interventions. To our knowledge, this is almost the first time to conduct systematically bibliometric analysis on the topic of procrastination and findings can provide an in-depth view of the patterns and trends in procrastination research.
    Language English
    Publishing date 2022-02-02
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.809044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The "Hand as Foot" teaching method in the respiratory system.

    Bi, Yueyang / Zhang, Xiaomin

    Asian journal of surgery

    2022  Volume 45, Issue 7, Page(s) 1496–1497

    MeSH term(s) Foot ; Hand ; Humans ; Lower Extremity ; Respiratory System ; Upper Extremity
    Language English
    Publishing date 2022-03-21
    Publishing country China
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2022.03.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: O-GlcNAcylation and Its Roles in Neurodegenerative Diseases.

    Du, Pengyang / Zhang, Xiaomin / Lian, Xia / Hölscher, Christian / Xue, Guofang

    Journal of Alzheimer's disease : JAD

    2024  Volume 97, Issue 3, Page(s) 1051–1068

    Abstract: As a non-classical post-translational modification, O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is widely found in human organ systems, particularly in our brains, and is indispensable for healthy cell biology. With the ... ...

    Abstract As a non-classical post-translational modification, O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is widely found in human organ systems, particularly in our brains, and is indispensable for healthy cell biology. With the increasing age of the global population, the incidence of neurodegenerative diseases is increasing, too. The common characteristic of these disorders is the aggregation of abnormal proteins in the brain. Current research has found that O-GlcNAcylation dysregulation is involved in misfolding or aggregation of these abnormal proteins to mediate disease progression, but the specific mechanism has not been defined. This paper reviews recent studies on O-GlcNAcylation's roles in several neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, Machado-Joseph's disease, and giant axonal neuropathy, and shows that O-GlcNAcylation, as glucose metabolism sensor, mediating synaptic function, participating in oxidative stress response and signaling pathway conduction, directly or indirectly regulates characteristic pathological protein toxicity and affects disease progression. The existing results suggest that targeting O-GlcNAcylation will provide new ideas for clinical diagnosis, prevention, and treatment of neurodegenerative diseases.
    MeSH term(s) Humans ; Neurodegenerative Diseases/metabolism ; Protein Processing, Post-Translational ; Proteins/metabolism ; Alzheimer Disease/pathology ; Acetylglucosamine/metabolism ; Disease Progression ; N-Acetylglucosaminyltransferases/metabolism
    Chemical Substances Proteins ; Acetylglucosamine (V956696549) ; N-Acetylglucosaminyltransferases (EC 2.4.1.-)
    Language English
    Publishing date 2024-01-03
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1440127-7
    ISSN 1875-8908 ; 1387-2877
    ISSN (online) 1875-8908
    ISSN 1387-2877
    DOI 10.3233/JAD-230955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Salvianolic Acid B Ameliorated Chemotherapeutic Injury of Cardiac Myocytes through the Nrf2/ARE Signaling Pathway.

    Wu, Yaping / Lin, Zhenjian / Bao, Yuyan / Liu, Yuebo / Zhang, Xiaomin

    Discovery medicine

    2024  Volume 36, Issue 181, Page(s) 415–423

    Abstract: Background: Cardiotoxicity has been corroborated to be the toxic influence of cisplatin (CDDP). Oxidative stress and cardiomyocyte apoptosis play a vital part in cardiotoxicity induced by CDDP. Salvianolic acid Salvianolic acid B (SalB) is a monomeric ... ...

    Abstract Background: Cardiotoxicity has been corroborated to be the toxic influence of cisplatin (CDDP). Oxidative stress and cardiomyocyte apoptosis play a vital part in cardiotoxicity induced by CDDP. Salvianolic acid Salvianolic acid B (SalB) is a monomeric component of Salvia miltiorrhiza, which has antioxidant and anti-inflammatory influences. In this research, we explored the mechanism of SalB in cardiotoxicity induced by CDDP.
    Method: 36 Wistar rats were separated into sham subgroup, CDDP (10 mg/kg) subgroup, CDDP (10 mg/kg) + SalB (1 μM) subgroup at random, CDDP (10 mg/kg) + SalB (5 μM) subgroup and CDDP (10 mg/kg) + SalB (10 μM) subgroup, Nicotinic Acid Riboside (NAR, 5 μM), with 6 rats in each subgroup. The cardiac function of rats in each subgroup was estimated by echocardiography, and hematoxylin-eosin (HE) staining and Masson staining corroborated the pathological changes of cardiac tissue. Biochemical kits were utilized for detecting the lactate dehydrogenase (LDH), creatine kinase (CK), interleukin-1β (IL-1β), IL-18, and caspase-1 concentrations in serum, superoxide dismutase (SOD), and malondialdehyde (MDA) in myocardial tissue, TdT-mediated dUTP Nick-End Labeling (TUNEL) staining, and flow cytometry were utilized for estimating the apoptosis level in myocardial tissue, western blot was used for estimating caspase-3, Bcl2-Associated X (Bax) levels in myocardial tissue and proteins levels related to Nuclear factor E2 related factor 2 (Nrf2) signal pathway.
    Results: CDDP-induced cardiac dysfunction, myocardial injury, boosted LDH and CK levels in serum (
    Conclusions: SalB ameliorates the injury of cardiomyocytes induced by chemotherapy through oxidative stress mediated by the Nrf2/antioxidant response element (ARE) signal pathway.
    MeSH term(s) Rats ; Animals ; Myocytes, Cardiac ; Antioxidant Response Elements ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Rats, Sprague-Dawley ; Cardiotoxicity/metabolism ; Rats, Wistar ; Signal Transduction ; Oxidative Stress ; Apoptosis ; Benzofurans ; Depsides
    Chemical Substances NF-E2-Related Factor 2 ; salvianolic acid B (C1GQ844199) ; Benzofurans ; Depsides
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2415544-5
    ISSN 1944-7930 ; 1944-7930
    ISSN (online) 1944-7930
    ISSN 1944-7930
    DOI 10.24976/Discov.Med.202436181.39
    Database MEDical Literature Analysis and Retrieval System OnLINE

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