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  1. Article ; Online: Bi-path color tunable plasmonic micro-nano hybrid structures for encrypted printing.

    Qi, Xiuping / Li, Xin / Miao, Jingying / Liu, Zhong / Fu, Shencheng / Zhang, Xintong

    Optics express

    2024  Volume 32, Issue 6, Page(s) 9384–9396

    Abstract: Colored information is crucial for humans to perceive the world. Plasmonic spectra modulation can serve as an effective means to create different colors. Although several solutions for plasmonic color-printing have been proposed, further information ... ...

    Abstract Colored information is crucial for humans to perceive the world. Plasmonic spectra modulation can serve as an effective means to create different colors. Although several solutions for plasmonic color-printing have been proposed, further information encryption has not received any attention. Herein, we exhibit a fine color modulation strategy to construct noble-metal-based micro-nano hybrid structures in the bi-path of photo-thermal deformation and liquid-phase-chemical reaction. Ag/Ta
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.511120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Conserved Intramolecular Ion-Pair Plays a Critical but Divergent Role in Regulation of Dimerization and Transport Function among the Monoamine Transporters.

    Chen, Sixiang / Huang, Xingyu / Zhang, Xintong / Li, Chan / Zhang, Yuan-Wei

    International journal of molecular sciences

    2024  Volume 25, Issue 7

    Abstract: The monoamine transporters, including the serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET), are the therapeutic targets for the treatment of many neuropsychiatric disorders. Despite significant progress in ... ...

    Abstract The monoamine transporters, including the serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET), are the therapeutic targets for the treatment of many neuropsychiatric disorders. Despite significant progress in characterizing the structures and transport mechanisms of these transporters, the regulation of their transport functions through dimerization or oligomerization remains to be understood. In the present study, we identified a conserved intramolecular ion-pair at the third extracellular loop (EL3) connecting TM5 and TM6 that plays a critical but divergent role in the modulation of dimerization and transport functions among the monoamine transporters. The disruption of the ion-pair interactions by mutations induced a significant spontaneous cross-linking of a cysteine mutant of SERT and an increase in cell surface expression but with an impaired specific transport activity. On the other hand, similar mutations of the corresponding ion-pair residues in both DAT and NET resulted in an opposite effect on their oxidation-induced dimerization, cell surface expression, and transport function. Reversible biotinylation experiments indicated that the ion-pair mutations slowed down the internalization of SERT but stimulated the internalization of DAT. In addition, cysteine accessibility measurements for monitoring SERT conformational changes indicated that substitution of the ion-pair residues resulted in profound effects on the rate constants for cysteine modification in both the extracellular and cytoplasmatic substrate permeation pathways. Furthermore, molecular dynamics simulations showed that the ion-pair mutations increased the interfacial interactions in a SERT dimer but decreased it in a DAT dimer. Taken together, we propose that the transport function is modulated by the equilibrium between monomers and dimers on the cell surface, which is regulated by a potential compensatory mechanism but with different molecular solutions among the monoamine transporters. The present study provided new insights into the structural elements regulating the transport function of the monoamine transporters through their dimerization.
    MeSH term(s) Dimerization ; Cysteine ; Serotonin Plasma Membrane Transport Proteins/genetics ; Biotinylation ; Cell Membrane ; Norepinephrine Plasma Membrane Transport Proteins ; Polymers
    Chemical Substances Cysteine (K848JZ4886) ; Serotonin Plasma Membrane Transport Proteins ; Norepinephrine Plasma Membrane Transport Proteins ; Polymers
    Language English
    Publishing date 2024-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25074032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Retraction Note: Ketamine exerts neurotoxic effects on the offspring of pregnant rats via the Wnt/β-catenin pathway.

    Zhang, Xintong / Zhao, Jinghua / Chang, Tian / Wang, Qi / Liu, Wenhan / Gao, Li

    Environmental science and pollution research international

    2024  Volume 31, Issue 15, Page(s) 23305

    Language English
    Publishing date 2024-03-05
    Publishing country Germany
    Document type Retraction of Publication
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32774-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  4. Article: Effectiveness on level of consciousness of non-invasive neuromodulation therapy in patients with disorders of consciousness: a systematic review and meta-analysis.

    Liu, Zhenyu / Zhang, Xintong / Yu, Binbin / Wang, Jiayue / Lu, Xiao

    Frontiers in human neuroscience

    2023  Volume 17, Page(s) 1129254

    Abstract: Background: Disorders of consciousness (DoC) commonly occurs secondary to severe neurological injury. A considerable volume of research has explored the effectiveness of different non-invasive neuromodulation therapy (NINT) on awaking therapy, however, ... ...

    Abstract Background: Disorders of consciousness (DoC) commonly occurs secondary to severe neurological injury. A considerable volume of research has explored the effectiveness of different non-invasive neuromodulation therapy (NINT) on awaking therapy, however, equivocal findings were reported.
    Objective: The aim of this study was to systematically investigate the effectiveness on level of consciousness of different NINT in patients with DoC and explore optimal stimulation parameters and characteristics of patients.
    Methods: PubMed, Embase, Web of Science, Scopus, and Cochrane central register of controlled trials were searched from their inception through November 2022. Randomized controlled trials, that investigated effectiveness on level of consciousness of NINT, were included. Mean difference (MD) with 95% confidence interval (CI) was evaluated as effect size. Risk of bias was assessed with revised Cochrane risk-of-bias tool.
    Results: A total of 15 randomized controlled trials with 345 patients were included. Meta-analysis was performed on 13 out of 15 reviewed trials indicating that transcranial Direct Current Stimulation (tDCS), Transcranial Magnetic Stimulation (TMS), and median nerve stimulation (MNS) all had a small but significant effect (MD 0.71 [95% CI 0.28, 1.13]; MD 1.51 [95% CI 0.87, 2.15]; MD 3.20 [95%CI: 1.45, 4.96]) on level of consciousness. Subgroup analyses revealed that patients with traumatic brain injury, higher initial level of consciousness (minimally conscious state), and shorter duration of prolonged DoC (subacute phase of DoC) reserved better awaking ability after tDCS. TMS also showed encouraging awaking effect when stimulation was applied on dorsolateral prefrontal cortex in patients with prolonged DoC.
    Conclusion: tDCS and TMS appear to be effective interventions for improving level of consciousness of patients with prolonged DoC. Subgroup analyses identified the key parameters required to enhance the effects of tDCS and TMS on level of consciousness. Etiology of DoC, initial level of consciousness, and phase of DoC could act as significant characteristics of patients related to the effectiveness of tDCS. Stimulation site could act as significant stimulation parameter related to the effectiveness of TMS. There is insufficient evidence to support the use of MNS in clinical practice to improve level of consciousness in patients with coma.
    Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=337780, identifier: CRD42022337780.
    Language English
    Publishing date 2023-05-24
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2425477-0
    ISSN 1662-5161
    ISSN 1662-5161
    DOI 10.3389/fnhum.2023.1129254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Research on the collapse characteristics of single cavitation bubble near solid particle by the VOF method.

    Lyu, Fengxia / Zhang, Xintong / Yuan, Huixin / Han, Saiyue / Tang, Ming

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e21855

    Abstract: In this paper, the collapse behavior of a single cavitation bubble at different distances near a solid particle of typical scales is numerically simulated and researched with the volume of fluid (VOF) method. Based on the key parameters analysis of the ... ...

    Abstract In this paper, the collapse behavior of a single cavitation bubble at different distances near a solid particle of typical scales is numerically simulated and researched with the volume of fluid (VOF) method. Based on the key parameters analysis of the pressure field, velocity vector, collapse time the tendency of cavitation bubble collapse characteristics at different distances during the change of particle size is studied with the variable of the distance and relative size between the particle and the cavitation bubble. The dimensionless distance parameter '
    Language English
    Publishing date 2023-11-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e21855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effects of Variations in Soil Moisture and Phosphorus Concentrations on the Diversity of the Arbuscular Mycorrhizal Fungi Community in an Agricultural Ecosystem

    Shao, Yizhen / Wang, Zhao / Liu, Wenjun / Zhang, Xintong / Wang, Jing / Guo, Peng

    Agriculture. 2023 June 20, v. 13, no. 6

    2023  

    Abstract: In farmland ecosystems, phosphorus and water have crucial roles. To elucidate the effects of phosphorus concentration and water management on arbuscular mycorrhizal fungi (AMF), field experiments were conducted in a farmland ecosystem (China). We ... ...

    Abstract In farmland ecosystems, phosphorus and water have crucial roles. To elucidate the effects of phosphorus concentration and water management on arbuscular mycorrhizal fungi (AMF), field experiments were conducted in a farmland ecosystem (China). We examined the effects of different treatments, including drought and normal phosphorus, normal water and normal phosphorus, drought and low phosphorus, and normal water and low phosphorus, on the AM fungal biomass, diversity, and community. Results showed great differences in the AMF under different water and phosphorus concentrations. When under a suitable drought treatment, the AMF became more abundant and more conducive to plant growth. The abundance of AMF varied with different phosphorus treatments, and the abundance of AMF in low-phosphorus treatments was higher, which is more suitable for plant growth. In conclusion, as water and phosphorus concentrations change, the community structure of AMF constantly changes. Only under the appropriate water and phosphorus concentration processing can AMF play its role well. Understanding the influence of different phosphorus concentrations and the moisture contents of AMF can play a role in the agricultural production of AMF, and it can also provide improved theoretical support.
    Keywords agricultural land ; agriculture ; agroecosystems ; community structure ; drought ; fungal biomass ; phosphorus ; plant growth ; soil water ; vesicular arbuscular mycorrhizae ; water management ; China
    Language English
    Dates of publication 2023-0620
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2651678-0
    ISSN 2077-0472
    ISSN 2077-0472
    DOI 10.3390/agriculture13061272
    Database NAL-Catalogue (AGRICOLA)

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  7. Book ; Online: Enhance Reasoning Ability of Visual-Language Models via Large Language Models

    Yang, Yueting / Zhang, Xintong / Han, Wenjuan

    2023  

    Abstract: Pre-trained visual language models (VLM) have shown excellent performance in image caption tasks. However, it sometimes shows insufficient reasoning ability. In contrast, large language models (LLMs) emerge with powerful reasoning capabilities. Therefore, ...

    Abstract Pre-trained visual language models (VLM) have shown excellent performance in image caption tasks. However, it sometimes shows insufficient reasoning ability. In contrast, large language models (LLMs) emerge with powerful reasoning capabilities. Therefore, we propose a method called TReE, which transfers the reasoning ability of a large language model to a visual language model in zero-shot scenarios. TReE contains three stages: observation, thinking, and re-thinking. Observation stage indicates that VLM obtains the overall information of the relative image. Thinking stage combines the image information and task description as the prompt of the LLM, inference with the rationals. Re-Thinking stage learns from rationale and then inference the final result through VLM.
    Keywords Computer Science - Computation and Language ; Computer Science - Artificial Intelligence
    Publishing date 2023-05-22
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Unique Substrate Recognition and Sodium-Substrate Binding Stoichiometry in a Bacterial Serotonin Transporter, TuriSERT.

    Li, Mu / Zhang, Xintong / Chen, Sixiang / Liu, Hanhe / Zhang, Yuan-Wei

    International journal of molecular sciences

    2023  Volume 24, Issue 23

    Abstract: All resolved high-resolution structures of the transporters in the neurotransmitter sodium symporter (NSS) family revealed that the NSS members share common structural and mechanistic features for substrate and ion binding and transport. However, a ... ...

    Abstract All resolved high-resolution structures of the transporters in the neurotransmitter sodium symporter (NSS) family revealed that the NSS members share common structural and mechanistic features for substrate and ion binding and transport. However, a recently reported bacterial orthologue of the human serotonin transporter (hSERT), TuriSERT, possesses a structural characteristic specific for amino acid substrate binding but does transport a biogenic amine. The unique structural feature of TuriSERT requires a novel configuration for coordinating its substrate and ions. In the present study, we characterized TuriSERT expressed in
    MeSH term(s) Humans ; Serotonin Plasma Membrane Transport Proteins/genetics ; Serotonin Plasma Membrane Transport Proteins/metabolism ; Serotonin/metabolism ; Sodium/metabolism ; Binding Sites ; Antidepressive Agents ; Symporters/genetics ; Symporters/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism
    Chemical Substances Serotonin Plasma Membrane Transport Proteins ; Serotonin (333DO1RDJY) ; Sodium (9NEZ333N27) ; Antidepressive Agents ; Symporters
    Language English
    Publishing date 2023-12-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242317112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Morphological characterization and genetic diversity of a new microsporidium,

    Weng, Meiqi / Zhang, Xintong / Xin, Zhaozhe / Xue, Sijia / Zhang, Qianqian / Li, Aihua / Zhang, Jinyong

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1125394

    Abstract: We reported a new ... ...

    Abstract We reported a new microsporidium
    MeSH term(s) Animals ; Microsporidia, Unclassified/genetics ; Phylogeny ; Microsporidia/genetics ; DNA, Ribosomal/genetics ; Crustacea/genetics ; Adipose Tissue ; Genetic Variation
    Chemical Substances DNA, Ribosomal
    Language English
    Publishing date 2023-01-27
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1125394
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Intraspecific genetic diversity of the fish-infecting microsporidian parasite

    Weng, Meiqi / Zhang, Xintong / Xin, Zhaozhe / Xue, Sijia / Zhang, Qianqian / Li, Aihua / Zhang, Jinyong

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1129136

    Abstract: Pseudokabatana ... ...

    Abstract Pseudokabatana alburnus
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1129136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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