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Article: Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient.

Barouqa, Mohammad / Zhang, Xuebao / Walde, Ryan / Ahmed, Zan / Mohammed, Rasha

2023 Volume 15, Issue 11, Page(s) e49451

Abstract: Sickle cell disease (SCD) is a chronic and prevalent hemoglobin disorder with various manifestations and complications depending on the organs involved. Red cell transfusion either simple or exchange is crucial due to its prophylactic and therapeutic ... ...

Abstract	Sickle cell disease (SCD) is a chronic and prevalent hemoglobin disorder with various manifestations and complications depending on the organs involved. Red cell transfusion either simple or exchange is crucial due to its prophylactic and therapeutic roles. We present a case showing serologic discrepancy between the red cells phenotype and the developed alloantibodies to emphasize the crucial role of molecular testing in SCD patients requiring chronic blood transfusion.
Language	English
Publishing date	2023-11-26
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.49451
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Article ; Online: FSH can improve semen parameters in patients with idiopathic oligoasthenoteratozoospermia: A systematic review and meta-analysis.

Zhang, Xuebao / Chen, Jie / Cui, Yuanqing / Jin, Yinshan / Wang, Xiong

Andrologia

2022 Volume 54, Issue 11, Page(s) e14596

Abstract: Follicle-stimulating hormone (FSH) is commonly used in assisted reproductive technology to promote the development and maturation of follicles in female patients. However, there is no consensus on treating FSH in males with idiopathic ... ...

Abstract	Follicle-stimulating hormone (FSH) is commonly used in assisted reproductive technology to promote the development and maturation of follicles in female patients. However, there is no consensus on treating FSH in males with idiopathic oligoasthenoteratozoospermia (iOAT), especially in patients with normal serum FSH levels. To determine the role of FSH in improving semen quality in patients with iOAT, we conducted a detailed search in the commonly used database to find all studies on FSH in the treatment of iOAT. We compared the results, including semen volume, sperm count, sperm concentration, percentage of forward sperm motility, percentage of total sperm motility, percentage of normal forms and DNA fragmentation index (DFI) between the two groups treated with FSH or not. A total of 12 randomized controlled trials and one retrospective case-control study, including 924 people, were included in our meta-analysis. We found that sperm counts (MD 17.75; 95% CI 11.53-23.98 and p < 0.00001) were significantly increased in patients treated with FSH, along with improvements in sperm concentration (MD 4.52; 95% CI 1.46-7.58 and p = 0.004), percentage of normal forms (MD 2.87; 95% CI 0.19-5.56 and p = 0.04) and DFI (MD -12.62; 95% CI -19.27-5.97 and p = 0.002). However, we found no significant differences in the two groups' changes in other semen parameters. The use of FSH can improve some semen parameters in patients with iOAT, such as sperm count, percentage of normal forms, sperm concentration and DFI.
MeSH term(s)	Humans ; Male ; Asthenozoospermia/drug therapy ; Case-Control Studies ; Follicle Stimulating Hormone/therapeutic use ; Infertility, Male/drug therapy ; Oligospermia/drug therapy ; Randomized Controlled Trials as Topic ; Retrospective Studies ; Semen ; Semen Analysis ; Sperm Count ; Sperm Motility ; Spermatozoa
Chemical Substances	Follicle Stimulating Hormone (9002-68-0)
Language	English
Publishing date	2022-09-14
Publishing country	Germany
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	7280-1
ISSN	1439-0272 ; 0303-4569
ISSN (online)	1439-0272
ISSN	0303-4569
DOI	10.1111/and.14596
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Zs.A 665: Show issues

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Article ; Online: Xanthogranulomatous pyelonephritis infected with the Providencia stuartii: a case report and literature review.

Xu, Zhunan / Cai, Tong / Zhang, Xuebao / Wu, Jitao / Liu, Chu

BMC nephrology

2021 Volume 22, Issue 1, Page(s) 356

Abstract: Background: Xanthogranulomatous pyelonephritis (XGP) is a rare and severe chronic inflammatory disease of the renal parenchyma, which is most commonly associated with super-infections by bacteria such as E. coli, Proteus mirabilis, and occasionally ... ...

Abstract	Background: Xanthogranulomatous pyelonephritis (XGP) is a rare and severe chronic inflammatory disease of the renal parenchyma, which is most commonly associated with super-infections by bacteria such as E. coli, Proteus mirabilis, and occasionally Pseudomonas species. Case presentation: Herein, we present a rare case of a patient with XGP infected with Providencia stuartii. Initially, the patient refused nephrectomy and underwent holmium laser lithotripsy and right ureteral stenting, followed by meropenem treatment of 7 days. Relapse occurred in the third month after discharge from the hospital, due to which she underwent a radical nephrectomy. Discussion: The diagnosis of XGP is confirmed by histopathology. The standard treatment for XGP is antibiotic therapy and radical nephrectomy, but partial nephrectomy may be appropriate in select cases.
MeSH term(s)	Adult ; Enterobacteriaceae Infections ; Female ; Humans ; Providencia ; Pyelonephritis, Xanthogranulomatous/microbiology
Language	English
Publishing date	2021-10-29
Publishing country	England
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2041348-8
ISSN	1471-2369 ; 1471-2369
ISSN (online)	1471-2369
ISSN	1471-2369
DOI	10.1186/s12882-021-02565-x
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Article ; Online: Urinary stone composition analysis of 3684 patients in the eastern Shandong region of China.

Zhang, Xuebao / Ma, Jiajia / Wang, Ning / Lin, Chunhua

The Journal of international medical research

2019 Volume 48, Issue 3, Page(s) 300060519887266

Abstract: Objective: There has not been a study that analyzed the composition of urinary stones from patients in the eastern Shandong region of China. Thus, we explored the composition of urinary stones in the eastern Shandong region of China and discuss the ... ...

Abstract	Objective: There has not been a study that analyzed the composition of urinary stones from patients in the eastern Shandong region of China. Thus, we explored the composition of urinary stones in the eastern Shandong region of China and discuss the clinical significance of the findings. Methods: A total of 3684 urinary calculi from the eastern Shandong region were collected in our study. Compositions of the stones were analyzed using an Automatic Infrared Spectrum Analysis System (type LIIR-20). The results were verified through manual analysis of the spectrograms, which was accompanied by polarizing microscopy and chemical analysis if necessary. Results: Among the 3684 specimens, there were 1767 single-component stones and 1917 mixed-component stones. According to the main components of the stones, the stones were divided into the following types: calcium oxalate monohydrate stones (1779, 48.3%), anhydrous uric acid stones (1105, 30.0%), carbonate apatite stones (590, 16.0%), ammonium magnesium phosphate hexahydrate stones (143, 3.9%), calcium oxalate dihydrate stones (36, 1.0%), and cystine stones (31, 0.8%). Conclusions: There was a relatively high rate of uric acid stones in patients from the eastern Shandong region of China.
MeSH term(s)	Calcium Oxalate ; China ; Humans ; Struvite/analysis ; Urinalysis ; Urinary Calculi/epidemiology
Chemical Substances	Calcium Oxalate (2612HC57YE) ; Struvite (AW3EJL1462)
Language	English
Publishing date	2019-11-28
Publishing country	England
Document type	Journal Article
ZDB-ID	184023-x
ISSN	1473-2300 ; 0300-0605 ; 0142-2596
ISSN (online)	1473-2300
ISSN	0300-0605 ; 0142-2596
DOI	10.1177/0300060519887266
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Zs.A 925: Show issues

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Article ; Online: Meta-analysis of the efficacy of sexual intercourse for distal ureteric stones.

Xu, Bin / Yan, Huilei / Zhang, Xuebao / Cui, Yuanshan

The Journal of international medical research

2019 Volume 47, Issue 2, Page(s) 497–504

Abstract: Objective: This meta-analysis was performed to evaluate the efficacy of sexual intercourse for treatment of distal ureteral stones.: Methods: Randomized controlled trials (RCTs) of sexual intercourse for treatment of distal ureteral stones were ... ...

Abstract	Objective: This meta-analysis was performed to evaluate the efficacy of sexual intercourse for treatment of distal ureteral stones. Methods: Randomized controlled trials (RCTs) of sexual intercourse for treatment of distal ureteral stones were searched using PubMed, EMBASE, and the Cochrane Controlled Trials Register. Results: Three RCTs comprising 240 patients were included in the meta-analysis, which showed that sexual intercourse was effective in treating distal ureteral stones. The expulsion rate of distal ureteral stones at the second week (odds ratio [OR] = 6.61, 95% confidence interval [CI]: 3.66 to 11.94), expulsion rate of distal ureteral stones at the fourth week (OR = 4.00, 95% CI: 2.09 to 7.64), and number of analgesic injections (mean difference [MD] = -0.79, 95% CI: -1.51 to -0.08) indicated that sexual intercourse was more effective than placebo. However, the mean expulsion time of distal ureteral stones (MD = -3.98, 95% CI: -8.77 to 0.81) showed no difference between sexual intercourse and placebo. Conclusions: Compared with placebo, sexual intercourse exhibited greater efficacy for the treatment of distal ureteral stones, whilst potentially alleviating pain.
MeSH term(s)	Coitus ; Humans ; Randomized Controlled Trials as Topic ; Ureteral Calculi/therapy
Language	English
Publishing date	2019-01-09
Publishing country	England
Document type	Journal Article ; Meta-Analysis
ZDB-ID	184023-x
ISSN	1473-2300 ; 0300-0605 ; 0142-2596
ISSN (online)	1473-2300
ISSN	0300-0605 ; 0142-2596
DOI	10.1177/0300060518814116
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Zs.A 925: Show issues

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Article: Treatment of a patient with total urinary calculi: a case report.

Ma, Jiajia / Zhang, Xuebao / Wang, Jipeng / Zhou, Zhongbao / Lin, Chunhua

Translational andrology and urology

2020 Volume 8, Issue 6, Page(s) 764–769

Abstract: Urinary tract stones are a general term for stone disease in various parts of the urinary system and are common diseases of the urinary system. According to the location of the stone, it is divided into kidney stones, ureteral stones, bladder stones, ... ...

Abstract	Urinary tract stones are a general term for stone disease in various parts of the urinary system and are common diseases of the urinary system. According to the location of the stone, it is divided into kidney stones, ureteral stones, bladder stones, urethra stones. Total urinary calculi occur less frequently, usually accompanied by severe clinical symptoms and difficult to treat. A 76-year-old man was admitted to hospital with repeated bladder stones for 7 years, repeated dysuria with frequent urination and dysuria for 2 months. After admission, the patient improved the relevant examination, and the patient was finally diagnosed with total urinary calculi combined with infection. After a series of orderly and effective treatments, especially the completion of the one-stage operation, the patient recovered smoothly and was discharged. Complicated whole-course urolithiasis is relatively rare and a single operation of total urinary calculi is feasible.
Language	English
Publishing date	2020-01-30
Publishing country	China
Document type	Case Reports
ZDB-ID	2851630-8
ISSN	2223-4691 ; 2223-4691 ; 2223-4683
ISSN (online)	2223-4691
ISSN	2223-4691 ; 2223-4683
DOI	10.21037/tau.2019.11.23
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Article: Assessment of Three-Dimensional Reconstruction in Percutaneous Nephrolithotomy for Complex Renal Calculi Treatment.

Tan, Haotian / Xie, Yaqi / Zhang, Xuebao / Wang, Wenting / Yuan, Hejia / Lin, Chunhua

Frontiers in surgery

2021 Volume 8, Page(s) 701207

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2021-10-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2773823-1
ISSN	2296-875X
ISSN	2296-875X
DOI	10.3389/fsurg.2021.701207
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Article ; Online: Phosphodiesterase-5 Inhibitors for Premature Ejaculation: Systematic Review and Meta-Analysis of Placebo-Controlled Trials.

Zhang, Xuebao / Chi, Nan / Sun, Miao / Shan, Zhengfei / Zhang, Yulian / Cui, Yuanshan

American journal of men's health

2021 Volume 14, Issue 3, Page(s) 1557988320916406

Abstract: The purpose of this analysis is to assess the efficacy and safety of phosphodiesterase-5 inhibitors (PDE5Is) for the treatment of premature ejaculation (PE). A comprehensive search was performed to ascertain from trials about PDE5Is for the treatment of ... ...

Abstract	The purpose of this analysis is to assess the efficacy and safety of phosphodiesterase-5 inhibitors (PDE5Is) for the treatment of premature ejaculation (PE). A comprehensive search was performed to ascertain from trials about PDE5Is for the treatment of PE and compare the results, including intravaginal ejaculatory latency time (IVELT), score of sexual satisfaction scale, and side effects, between the group treated with PDE5Is and that treated with placebo. Seven studies involving a total of 471 patients were included in this meta-analysis. This analysis showed that patients who were treated with PDE5Is had significantly increased IVELT (mean difference [MD] 2.60; 95% CI [1.85, 3.36];
MeSH term(s)	Humans ; Male ; Phosphodiesterase 5 Inhibitors/therapeutic use ; Placebo Effect ; Premature Ejaculation/drug therapy
Chemical Substances	Phosphodiesterase 5 Inhibitors
Language	English
Publishing date	2021-06-01
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	2275106-3
ISSN	1557-9891 ; 1557-9883
ISSN (online)	1557-9891
ISSN	1557-9883
DOI	10.1177/1557988320916406
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Article ; Online: Intratunical injection of rat-derived bone marrow mesenchymal stem cells prevents fibrosis and is associated with increased Smad7 expression in a rat model of Peyronie's disease.

Wang, Wenting / Ding, Weifang / Zhang, Xuebao / Wu, Shuang / Yu, Tianxi / Cui, Xin / Xie, Yaqi / Yang, Diandong / Lin, Chunhua

Stem cell research & therapy

2022 Volume 13, Issue 1, Page(s) 390

Abstract: Objective: Peyronie's disease (PD) is a fibrotic disorder of the penis, but effective treatments are lacking. Here, we observed the effects of rat-derived bone marrow mesenchymal stem cells (BMSCs) injection in the active phase and chronic phase in a ... ...

Abstract	Objective: Peyronie's disease (PD) is a fibrotic disorder of the penis, but effective treatments are lacking. Here, we observed the effects of rat-derived bone marrow mesenchymal stem cells (BMSCs) injection in the active phase and chronic phase in a rat model of PD, and the possible mechanism was analysed with fibroblasts derived from rat penile tunica albuginea (TA). Methods: Thirty-two male Sprague-Dawley rats were divided into four groups. In sham group, the rats were injected with 50 µL of vehicle. In the PD group, the rats were injected with 50 µg TGF-β1. In the PD + BMSCs early treatment group, the rats were injected with 50 µg TGF-β1 and injected with 1 × 10 Results: Erectile function obviously improved, and fibrosis of penile TA was prevented after BMSCs treatment compared with that in the rats with PD. Furthermore, the effects of BMSCs treatment in the active phase were better than those in the chronic phase. After cocultured with BMSCs, cell viability was not affected, Smad7 expression was upregulated, and collagen 3, elastase-2B and osteopontin levels were decreased in the TGF-β1-treated fibroblasts. After transfection with Smad7 siRNA, the antifibrotic effects of BMSCs were offset. Conclusions: The antifibrotic effects of BMSCs treatment in the active phase of the PD rat model were better than those in the chronic phase. A possible mechanism of BMSCs treatment was related to increased Smad7 expression, suggesting a possible effective and safe procedure for the treatment of PD.
MeSH term(s)	Animals ; Bone Marrow Cells/metabolism ; Disease Models, Animal ; Erectile Dysfunction/therapy ; Fibrosis ; Humans ; Male ; Mesenchymal Stem Cells/metabolism ; Osteopontin/metabolism ; Pancreatic Elastase ; Penile Induration/pathology ; Penile Induration/therapy ; RNA, Small Interfering ; Rats ; Rats, Sprague-Dawley ; Smad7 Protein/metabolism ; Transforming Growth Factor beta1/genetics ; Transforming Growth Factor beta1/metabolism
Chemical Substances	RNA, Small Interfering ; SMAD7 protein, human ; Smad7 Protein ; Smad7 protein, rat ; Transforming Growth Factor beta1 ; Osteopontin (106441-73-0) ; Pancreatic Elastase (EC 3.4.21.36)
Language	English
Publishing date	2022-07-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2548671-8
ISSN	1757-6512 ; 1757-6512
ISSN (online)	1757-6512
ISSN	1757-6512
DOI	10.1186/s13287-022-03090-w
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Article ; Online: Novel

Chen, Jie / Li, Feng-Hua / Zhang, Xue-Bao / Du, Zhao-Li / Jin, Yin-Shan / Cui, Yuan-Qing / Wang, Xiong

Asian journal of andrology

2022 Volume 25, Issue 4, Page(s) 544–546

MeSH term(s)	Cell Cycle Proteins/genetics ; Mutation
Chemical Substances	Cell Cycle Proteins
Language	English
Publishing date	2022-08-10
Publishing country	China
Document type	Letter
ZDB-ID	2075824-8
ISSN	1745-7262 ; 1008-682X
ISSN (online)	1745-7262
ISSN	1008-682X
DOI	10.4103/aja202280
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Zs.A 5739: Show issues

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