LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 12

Search options

  1. Article ; Online: Integrating satellite and reanalysis precipitation products for SWAT hydrological simulation in the Jing River Basin, China.

    Zhang, Yangkai / Gao, Yang / Xu, Liujia / Liu, Zhengguang / Wu, Lei

    Environmental science and pollution research international

    2024  Volume 31, Issue 13, Page(s) 20534–20555

    Abstract: In hydrological studies, satellite and reanalysis precipitation products are increasingly being used to supplement gauge observation data. This study designed the composite simulation index (COSI), considering two factors: F1 (data accuracy assessment) ... ...

    Abstract In hydrological studies, satellite and reanalysis precipitation products are increasingly being used to supplement gauge observation data. This study designed the composite simulation index (COSI), considering two factors: F1 (data accuracy assessment) and F2 (hydrological simulation performance), to compare the performance of the latest satellite-based and reanalysis-based precipitation products (IMERG, ERA5, ERA5-Land), the prior precipitation products (TRMM, CMADS), and the multi-source weighted-ensemble precipitation (MSWEP). The Soil and Water Assessment Tool (SWAT) model was then applied to compare and analyze the hydrological simulation performance of four preferred products using three data fusion methods including simple model averaging, variance-based weighted averaging, and the latest quantile-based Bayesian model averaging (QBMA). The results can be summarized as follows: (1) Reanalysis products are superior to satellite-based products in terms of F1. However, the satellite-based precipitation products exhibit less BIAS and relatively higher F2, while the MSWEP has relatively high performance on both F1 and F2. (2) Among reanalysis-based precipitation products, CMADS has the best COSI value of 0.53. Although ERA5-Land shows good performance for individual parameters, the comprehensive assessment reveals that ERA5 outperforms ERA5-Land in terms of both F1 and F2. (3) IMERG and TRMM exhibit similar spatiotemporal patterns and similar F1, but IMERG is superior in F2. (4) QBMA outperformed traditional methods in F2, improving the NS coefficient of SWAT model from 0.74 to 0.85. These findings provide a useful reference for analyzing the strengths and limitations of satellite-based and reanalysis precipitation products, and also provide valuable ideas for the combined application of multi-source precipitation products in hydrological studies.
    MeSH term(s) Soil ; Rivers ; Bayes Theorem ; Hydrology ; China
    Chemical Substances Soil
    Language English
    Publishing date 2024-02-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32482-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Emerging applications of single-cell profiling in precision medicine of atherosclerosis.

    Lin, Huiling / Zhang, Ming / Hu, Mi / Zhang, Yangkai / Jiang, WeiWei / Tang, Wanying / Ouyang, Yuxin / Jiang, Liping / Mi, Yali / Chen, Zhi / He, Pingping / Zhao, Guojun / Ouyang, Xinping

    Journal of translational medicine

    2024  Volume 22, Issue 1, Page(s) 97

    Abstract: Atherosclerosis is a chronic, progressive, inflammatory disease that occurs in the arterial wall. Despite recent advancements in treatment aimed at improving efficacy and prolonging survival, atherosclerosis remains largely incurable. In this review, we ... ...

    Abstract Atherosclerosis is a chronic, progressive, inflammatory disease that occurs in the arterial wall. Despite recent advancements in treatment aimed at improving efficacy and prolonging survival, atherosclerosis remains largely incurable. In this review, we discuss emerging single-cell sequencing techniques and their novel insights into atherosclerosis. We provide examples of single-cell profiling studies that reveal phenotypic characteristics of atherosclerosis plaques, blood, liver, and the intestinal tract. Additionally, we highlight the potential clinical applications of single-cell analysis and propose that combining this approach with other techniques can facilitate early diagnosis and treatment, leading to more accurate medical interventions.
    MeSH term(s) Humans ; Precision Medicine ; Atherosclerosis ; Plaque, Atherosclerotic ; Arteries ; Liver
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2118570-0
    ISSN 1479-5876 ; 1479-5876
    ISSN (online) 1479-5876
    ISSN 1479-5876
    DOI 10.1186/s12967-023-04629-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Development of a hydraulically controlled piston-pressurized pulsed water jet device and its application potential for hard rock breaking.

    Ling, Yuanfei / Ge, Zhaolong / Tang, Jiren / Lu, Yiyu / Zhang, Yangkai / Wang, Lei

    The Review of scientific instruments

    2021  Volume 92, Issue 8, Page(s) 85101

    Abstract: To improve the efficiency of hard rock breaking by a pulsed water jet (PWJ), a hydraulically controlled piston-pressurized PWJ (HCPPPWJ) device has been developed, by which the large amplitude pressurization of the jet could be realized through the ... ...

    Abstract To improve the efficiency of hard rock breaking by a pulsed water jet (PWJ), a hydraulically controlled piston-pressurized PWJ (HCPPPWJ) device has been developed, by which the large amplitude pressurization of the jet could be realized through the motion coupling of the piston and the valve core inside the device without requiring additional control or ultra-high-pressure components. Under the continuous injection of low-pressure hydraulic oil, the device has a stable pressurization effect and controllable pulse pressure and pulse frequency. The jet pressure varies periodically with the alternation of high and low pressures; in the rising stage of the pulse pressure, the jet morphology presents an umbrella-like thin-layer structure, which ensures an effective initial impact force of the jet in contact with the target. With the addition of high-frequency stress waves and water wedge pressure, local flaky exfoliation was observed when the granite surface was eroded, and the maximum radius and volume of the erosion pit were greater than those in the case of employing a continuous water jet. Compared with the interrupted PWJ, the HCPPPWJ efficiently utilizes the jet energy during the erosion process, and the specific energy is lower. The results prove that the HCPPPWJ device is an advanced tool in the field of hard rock breaking.
    Language English
    Publishing date 2021-09-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209865-9
    ISSN 1089-7623 ; 0034-6748
    ISSN (online) 1089-7623
    ISSN 0034-6748
    DOI 10.1063/5.0052853
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Endocan: A Key Player of Cardiovascular Disease.

    Chen, Jinzhi / Jiang, Liping / Yu, Xiao-Hua / Hu, Mi / Zhang, Yang-Kai / Liu, Xin / He, Pingping / Ouyang, Xinping

    Frontiers in cardiovascular medicine

    2022  Volume 8, Page(s) 798699

    Abstract: Endothelial dysfunction is considered to be an early change in atherosclerosis. Endocan, also known as endothelial cell specific molecule-1, is a soluble proteoglycan mainly secreted by endothelial cells. Inflammatory factors such as IL-1β and TNF-α can ... ...

    Abstract Endothelial dysfunction is considered to be an early change in atherosclerosis. Endocan, also known as endothelial cell specific molecule-1, is a soluble proteoglycan mainly secreted by endothelial cells. Inflammatory factors such as IL-1β and TNF-α can up regulate the expression of endocan and then affect the expression of cell adhesion molecules, such as ICAM-1 and VCAM-1, which play an important role in promoting leukocyte migration and inflammatory response. Elevated plasma levels of endocan may reflect endothelial activation and dysfunction, and is considered to be a potential immuno-inflammatory marker that may be related to cardiovascular disease. In the case of hypertension, diabetes, angina pectoris and acute myocardial infarction, the increase or decrease of serum endocan levels is of great significance. Here, we reviewed the current research on endocan, and emphasis its possible clinical value as a prognostic marker of cardiovascular disease. Endocan may be a useful biomarker for the prognosis of cardiovascular disease, but more research is needed on its mechanism of action.
    Language English
    Publishing date 2022-01-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2021.798699
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: IGF‑1 inhibits palmitic acid‑induced mitochondrial apoptosis in macrophages.

    Tang, Wanying / Zhang, Ming / Wang, Yu / Ma, Dan / Hu, Mi / Zhang, Yangkai / Lin, Huiling / Jiang, Weiwei / Ouyang, Yuxin / Jiang, Liping / He, Pingping / Zhao, Guojun / Ouyang, Xinping

    Molecular medicine reports

    2023  Volume 28, Issue 6

    Abstract: Insulin growth factor‑1 (IGF‑1) is an endocrine regulator that plays an important role in normal growth and development. IGF‑1 mediated effects may result in protecting macrophages from immunometabolic response. However, it is unclear whether IGF‑1 has a ...

    Abstract Insulin growth factor‑1 (IGF‑1) is an endocrine regulator that plays an important role in normal growth and development. IGF‑1 mediated effects may result in protecting macrophages from immunometabolic response. However, it is unclear whether IGF‑1 has a protective effect on fatty acid‑induced macrophages damage. In the present study, THP‑1 cells were differentiated into macrophages and stimulated with palmitic acid (PA) in the absence or presence of IGF‑1. Macrophages apoptosis was measured by Cell Counting Kit‑8 assay, flow cytometry, Hoechst 33342 staining and western blotting. The mitochondrial damage was evaluated using JC‑1 staining and mitochondrial reactive oxygen species detection. The activation of mitophagy was assessed using immunofluorescence and western blotting. As a result, IGF‑1 significantly restored the survival rate in macrophages, while the apoptosis was inhibited through mitochondrial pathway. In addition, IGF‑1 protected the mitochondrial damage induced by PA. Furthermore, PA induced mitophagy via phosphatase and tensin homolog‑induced putative kinase protein 1/Parkin, which was reversed by IGF‑1. Taken together, the present study demonstrated the protective effect of IGF‑1 on PA‑induced mitochondrial apoptosis in macrophages, which might provide a potential therapeutic strategy for treatment of lipotoxicity.
    MeSH term(s) Insulin/pharmacology ; Palmitic Acid/toxicity ; Insulin-Like Growth Factor I/pharmacology ; Apoptosis ; Mitophagy ; Reactive Oxygen Species/metabolism ; Ubiquitin-Protein Ligases/metabolism
    Chemical Substances Insulin ; Palmitic Acid (2V16EO95H1) ; Insulin-Like Growth Factor I (67763-96-6) ; Reactive Oxygen Species ; Ubiquitin-Protein Ligases (EC 2.3.2.27)
    Language English
    Publishing date 2023-11-03
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2469505-1
    ISSN 1791-3004 ; 1791-2997
    ISSN (online) 1791-3004
    ISSN 1791-2997
    DOI 10.3892/mmr.2023.13121
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Correction to: The role of Circular RNAs in Ischemic Stroke.

    Jiang, Weiwei / Long, Xiongquan / Li, Zhicheng / Hu, Mi / Zhang, Yangkai / Lin, Huiling / Tang, Wanying / Ouyang, Yuxin / Jiang, Liping / Chen, Jinzhi / He, Pingping / Ouyang, Xinping

    Neurochemical research

    2023  Volume 48, Issue 9, Page(s) 2621

    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-023-03948-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: The Role of Circular RNAs in Ischemic Stroke.

    Jiang, Weiwei / Long, Xiongquan / Li, Zhicheng / Hu, Mi / Zhang, Yangkai / Lin, Huiling / Tang, Wanying / Ouyang, Yuxin / Jiang, Liping / Chen, Jinzhi / He, Pingping / Ouyang, Xinping

    Neurochemical research

    2023  Volume 48, Issue 9, Page(s) 2607–2620

    Abstract: Ischemic stroke (IS), a devastating condition characterized by intracranial artery stenosis and middle cerebral artery occlusion leading to insufficient oxygen supply to the brain, is a major cause of death and physical disability worldwide. Recent ... ...

    Abstract Ischemic stroke (IS), a devastating condition characterized by intracranial artery stenosis and middle cerebral artery occlusion leading to insufficient oxygen supply to the brain, is a major cause of death and physical disability worldwide. Recent research has demonstrated the critical role of circular RNAs (circRNAs), a class of covalently enclosed noncoding RNAs that are widespread in eukaryotic cells, in regulating various physiological and pathophysiological cellular processes, including cell apoptosis, autophagy, synaptic plasticity, and neuroinflammation. In the past few years, circRNAs have attracted extensive attention in the field of IS research. This review summarizes the current understanding of the mechanisms underlying the involvement of circRNAs in IS development. A better understanding of circRNA-mediated pathogenic mechanisms in IS may pave the way for translating circRNA research into clinical practice, ultimately improving the clinical outcomes of IS patients.
    MeSH term(s) Humans ; RNA, Circular/genetics ; Ischemic Stroke/genetics ; Brain/pathology ; Brain Ischemia/genetics ; Brain Ischemia/pathology ; Infarction, Middle Cerebral Artery/pathology ; Stroke/genetics
    Chemical Substances RNA, Circular
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-023-03935-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Histone Deacetylase 3: A Potential Therapeutic Target for Atherosclerosis.

    Jiang, Li-Ping / Yu, Xiao-Hua / Chen, Jin-Zhi / Hu, Mi / Zhang, Yang-Kai / Lin, Hui-Ling / Tang, Wan-Ying / He, Ping-Ping / Ouyang, Xin-Ping

    Aging and disease

    2022  Volume 13, Issue 3, Page(s) 773–786

    Abstract: Atherosclerosis, the pathological basis of most cardiovascular disease, is characterized by plaque formation in the intima. Secondary lesions include intraplaque hemorrhage, plaque rupture, and local thrombosis. Vascular endothelial function impairment ... ...

    Abstract Atherosclerosis, the pathological basis of most cardiovascular disease, is characterized by plaque formation in the intima. Secondary lesions include intraplaque hemorrhage, plaque rupture, and local thrombosis. Vascular endothelial function impairment and smooth muscle cell migration lead to vascular dysfunction, which is conducive to the formation of macrophage-derived foam cells and aggravates inflammatory response and lipid accumulation that cause atherosclerosis. Histone deacetylase (HDAC) is an epigenetic modifying enzyme closely related to chromatin structure and gene transcriptional regulation. Emerging studies have demonstrated that the Class I member HDAC3 of the HDAC super family has cell-specific functions in atherosclerosis, including 1) maintenance of endothelial integrity and functions, 2) regulation of vascular smooth muscle cell proliferation and migration, 3) modulation of macrophage phenotype, and 4) influence on foam cell formation. Although several studies have shown that HDAC3 may be a promising therapeutic target, only a few HDAC3-selective inhibitors have been thoroughly researched and reported. Here, we specifically summarize the impact of HDAC3 and its inhibitors on vascular function, inflammation, lipid accumulation, and plaque stability in the development of atherosclerosis with the hopes of opening up new opportunities for the treatment of cardiovascular diseases.
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2625789-0
    ISSN 2152-5250
    ISSN 2152-5250
    DOI 10.14336/AD.2021.1116
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Effect of sulfamethazine on anaerobic digestion of manure mediated by biochar.

    Zhang, Yangkai / Cao, Liu / Fu, Haibin / Zhang, Min / Meng, Jun / Althakafy, Jalal T / Abo-Dief, Hala M / El-Bahy, Salah M / Zhang, Yushun / Wei, Huanhuan / Xu, Ben Bin / Guo, Zhanhu

    Chemosphere

    2022  Volume 306, Page(s) 135567

    Abstract: Antibiotic contamination from animal production and wastewater treatment process will release antibiotic resistant genes to the environment and potentially threaten human health. Meanwhile, the residual antibiotic in manure could have inactive impacts on ...

    Abstract Antibiotic contamination from animal production and wastewater treatment process will release antibiotic resistant genes to the environment and potentially threaten human health. Meanwhile, the residual antibiotic in manure could have inactive impacts on anaerobic digestion (AD). This study explores the effect of sulfamethazine on manure AD mediated by biochar. The results show that biochar weakens the adverse effects of sulfamethazine on AD by adsorption sulfamethazine during the initial stage (0-3 days) of AD and promoting the growth of hydrolytic bacteria (especially Firmicutes and Bacteroidetes) and methanogens (especially Methanothrix and Methanosarcina). Besides, the presence of biochar improves the biogas production capacity of AD and promotes microbial diversity and community richness. Thus, the addition of biochar greatly reduces sulfamethazine and is testified to be a desirable strategy to mitigate the inhibition of sulfamethazine on AD.
    MeSH term(s) Anaerobiosis ; Animals ; Anti-Bacterial Agents/pharmacology ; Bioreactors/microbiology ; Charcoal ; Digestion ; Humans ; Manure/microbiology ; Methane ; Sulfamethazine/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Manure ; biochar ; Charcoal (16291-96-6) ; Sulfamethazine (48U51W007F) ; Methane (OP0UW79H66)
    Language English
    Publishing date 2022-07-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.135567
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Effect of sulfamethazine on anaerobic digestion of manure mediated by biochar

    Zhang, Yangkai / Cao, Liu / Fu, Haibin / Zhang, Min / Meng, Jun / Althakafy, Jalal T. / Abo-Dief, Hala M. / El-Bahy, Salah M. / Zhang, Yushun / Wei, Huanhuan / Xu, Ben Bin / Guo, Zhanhu

    Chemosphere. 2022 Nov., v. 306

    2022  

    Abstract: Antibiotic contamination from animal production and wastewater treatment process will release antibiotic resistant genes to the environment and potentially threaten human health. Meanwhile, the residual antibiotic in manure could have inactive impacts on ...

    Abstract Antibiotic contamination from animal production and wastewater treatment process will release antibiotic resistant genes to the environment and potentially threaten human health. Meanwhile, the residual antibiotic in manure could have inactive impacts on anaerobic digestion (AD). This study explores the effect of sulfamethazine on manure AD mediated by biochar. The results show that biochar weakens the adverse effects of sulfamethazine on AD by adsorption sulfamethazine during the initial stage (0–3 days) of AD and promoting the growth of hydrolytic bacteria (especially Firmicutes and Bacteroidetes) and methanogens (especially Methanothrix and Methanosarcina). Besides, the presence of biochar improves the biogas production capacity of AD and promotes microbial diversity and community richness. Thus, the addition of biochar greatly reduces sulfamethazine and is testified to be a desirable strategy to mitigate the inhibition of sulfamethazine on AD.
    Keywords Bacteroidetes ; Firmicutes ; Methanosarcina ; adsorption ; anaerobic digestion ; animal production ; antibiotic residues ; antibiotics ; biochar ; gas production (biological) ; human health ; methanogens ; sulfamethazine ; wastewater treatment
    Language English
    Dates of publication 2022-11
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.135567
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top