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Article ; Online: Adverse childhood experiences and depressive symptoms among adolescents during the COVID-19 pandemic: mediating roles of poor sleep quality and psychological inflexibility.

Ye, Baojuan / Wang, Qipeng / Zhang, Yanzhen / Yang, Qiang

2023 Volume 28, Issue 8, Page(s) 2095–2107

Abstract: Previous studies have found that adverse childhood experiences can lead to depressive symptoms. But the underlying mechanisms have not been determined. Guided by the 3-P model of insomnia and acceptance and commitment therapy, this study examined the ... ...

Abstract	Previous studies have found that adverse childhood experiences can lead to depressive symptoms. But the underlying mechanisms have not been determined. Guided by the 3-P model of insomnia and acceptance and commitment therapy, this study examined the mediating role of poor sleep quality and psychological inflexibility in the relationship between adverse childhood experiences and depressive symptoms during the COVID-19 pandemic. A total of 996 senior high school students in China (Mage = 16.57 years; SD = 1.03) completed the self-report measures of adverse childhood experiences, depressive symptoms, poor sleep quality, and psychological inflexibility. Multiple mediation analysis revealed that adverse childhood experiences were related to depressive symptoms through poor sleep quality and psychological inflexibility, serially. These findings point to potential targets in the prevention of and intervention in adolescent depressive symptoms.
MeSH term(s)	Humans ; Adolescent ; Depression/epidemiology ; Depression/psychology ; Sleep Quality ; Sleep Initiation and Maintenance Disorders/epidemiology ; Adverse Childhood Experiences ; Acceptance and Commitment Therapy ; Pandemics ; COVID-19/epidemiology
Language	English
Publishing date	2023-03-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1477841-5
ISSN	1465-3966 ; 1354-8506
ISSN (online)	1465-3966
ISSN	1354-8506
DOI	10.1080/13548506.2023.2190986
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Application of apical negative pressure irrigation in the nonsurgical treatment of radicular cysts: A case report.

Chen, Gong-Pei / Zhang, Yan-Zhen / Ling, Dan-Hua

World journal of clinical cases

2023 Volume 11, Issue 15, Page(s) 3612–3618

Abstract: Background: Radicular cysts are one of the most common odontogenic cystic lesions found in the jaw. Nonsurgical treatment of large radicular cysts is a topic of ongoing debate, and there is still no clear consensus on the most effective therapies. The ... ...

Abstract	Background: Radicular cysts are one of the most common odontogenic cystic lesions found in the jaw. Nonsurgical treatment of large radicular cysts is a topic of ongoing debate, and there is still no clear consensus on the most effective therapies. The apical negative pressure irrigation system aspirates the cystic fluid and releases the static pressure in the radicular cyst, representing a minimally invasive approach for decompression. In this case, the radicular cyst was in close proximity to the mandibular nerve canal. We used nonsurgical endodontic treatment with a homemade apical negative pressure irrigation system and the prognosis was good. Case summary: A 27-year-old male presented to our Department of General Dentistry with complaints of pain in the mandibular right molar when chewing. The patient had no history of drug allergies or systemic disease. A multidisciplinary management approach was designed and included root canal retreatment with a homemade apical negative pressure irrigation system, deep margin elevation and prosthodontic treatment. According to a 1-year follow-up period, the patient showed a favorable outcome. Conclusion: This report reveals that nonsurgical treatment with an apical negative pressure irrigation system may provide new insights into the treatment of radicular cysts.
Language	English
Publishing date	2023-04-08
Publishing country	United States
Document type	Case Reports
ISSN	2307-8960
ISSN	2307-8960
DOI	10.12998/wjcc.v11.i15.3612
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Article ; Online: The predictive value of noninvasive prenatal screening for copy number variations: a cohort study and a systematic meta-analysis.

Wen, Li / Zhang, Yanzhen / Gao, Jiye / Hu, Wensheng

Expert review of molecular diagnostics

2023 Volume 23, Issue 8, Page(s) 713–722

Abstract: Objective: To assess the diagnostic accuracy of noninvasive prenatal screening (NIPS) in screening for copy number variations (CNVs).: Methods: We conducted a systematic review and meta-analysis by combining our study results with those reported in ... ...

Abstract	Objective: To assess the diagnostic accuracy of noninvasive prenatal screening (NIPS) in screening for copy number variations (CNVs). Methods: We conducted a systematic review and meta-analysis by combining our study results with those reported in other articles. We retrospectively collected the data of pregnant women with NIPS testing in the Hangzhou Women's Hospital from December 2019 to February 2022. Simultaneously, a systematic search of PubMed, EMBASE, and Web of Science was carried out to identify all relevant peer-reviewed publications. Statistical analysis was performed based on the random-effects model to determine a pooled estimate of the positive predictive value (PPV). Results: A total of 29 studies involving 2,667 women were included for analysis. The pooled PPV of NIPS in the detection of CNVs was 32.86% (95% confidence interval [24.61-41.64]). Statistical heterogeneity was high, while no significant publication bias was found in this meta-analysis. There were insufficient data to accurately determine sensitivity and specificity, as most studies only performed confirmatory tests on high-risk women. Conclusions: The PPV of NIPS in screening for CNVs was approximately 33%. Cautions should be kept in mind for the pretest guidance and subsequent after-test counseling when offering such genome-wide NIPS tests.
MeSH term(s)	Pregnancy ; Female ; Humans ; Prenatal Diagnosis/methods ; Noninvasive Prenatal Testing/methods ; Cohort Studies ; DNA Copy Number Variations ; Retrospective Studies
Language	English
Publishing date	2023-07-07
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2112530-2
ISSN	1744-8352 ; 1473-7159
ISSN (online)	1744-8352
ISSN	1473-7159
DOI	10.1080/14737159.2023.2233415
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Article ; Online: Efficacy of enzyme‑induced collagen crosslinking on porcine cornea.

Zhang, Shijie / Zhang, Wenbo / Xiao, Shiyu / Zhang, Yanzhen / Chen, Duo / Liu, Xiaoyu / Wu, Yuan

Experimental and therapeutic medicine

2024 Volume 27, Issue 2, Page(s) 87

Abstract: The purpose of the present study was to investigate the effect of a new crosslinking (CXL) method, induced by enzymes, on porcine corneas. Corneal strip (10x3 mm) pairs obtained from 60 fresh porcine eyes were harvested and divided into four groups, ... ...

Abstract	The purpose of the present study was to investigate the effect of a new crosslinking (CXL) method, induced by enzymes, on porcine corneas. Corneal strip (10x3 mm) pairs obtained from 60 fresh porcine eyes were harvested and divided into four groups, Groups A-D. Each pair of corneal strips was incised from the central part of the same cornea; one was incubated in transglutaminase (Tgase) solution (microbial Tgase 2 produced by tissue engineering) and the other remained untreated as a control. CXL strips of Groups A-D were incubated with 2, 1, 0.5 and 0.25 U/ml Tgase solution, respectively at 37˚C for 30 min. After that, tensile strain measurements were performed for all strips. One cornea from each group was chosen randomly for hematoxylin and eosin, and Masson staining to identify histological morphology changes. The elastic modulus of treated corneas of Groups A-D were 6.56±2.93, 4.72±1.29, 5.24±2.13 and 3.48±1.60 MPa (mean ± SD), respectively at a strain of 20%, and had a 66, 43, 36 and -6% increase compared with those of their control strips. Compared with the control strips, the elastic modulus of the treated strips significantly increased in Groups A-C. The central corneal thickness of the treated corneas in Groups A-D were 1.54±0.14, 1.41±0.15, 1.47±0.11 and 1.43±0.13 µm, respectively; however, there was not a statistically significant difference compared with the control group. No reduction in corneal transparency was observed, and no obvious abnormalities were found in corneal morphology. CXL mediated by enzymes can lead to a notable enhancement in the biomechanical characteristics of the cornea while maintaining its structural integrity. Enzyme-induced CXL could be a new generation CXL method for strengthening the cornea.
Language	English
Publishing date	2024-01-08
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2683844-8
ISSN	1792-1015 ; 1792-0981
ISSN (online)	1792-1015
ISSN	1792-0981
DOI	10.3892/etm.2024.12377
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Article ; Online: Outcome of nonsurgical management of large cyst-like periapical lesions using a modified apical negative pressure irrigation system: a case series study.

Ling, Danhua / Chen, Yun / Chen, Gongpei / Zhang, Yanzhen / Wang, Yanhong / Wang, Ying / He, Fuming

BMC oral health

2024 Volume 24, Issue 1, Page(s) 336

Abstract: Objective: To assess the effectiveness of a self-constructed modified apical negative pressure irrigation (ANPI) system employing commonly used clinical instruments in nonsurgical root canal therapy (NSRCT) for large cyst-like periapical lesions (LCPLs). ...

Abstract	Objective: To assess the effectiveness of a self-constructed modified apical negative pressure irrigation (ANPI) system employing commonly used clinical instruments in nonsurgical root canal therapy (NSRCT) for large cyst-like periapical lesions (LCPLs). Methods: From 2017 to 2022, 35 patients diagnosed with LCPLs (5-15 mm) via preoperative clinical and radiographic evaluations of endodontic origin underwent NSRCT combined with ANPI. These patients were subjected to postoperative clinical and radiographic follow-up at 3 months, 6 months, 1 year, 2 years, 3 years, and 4 years, with a CBCT scan specifically conducted at 6-month follow-up. Through the reconstruction of three-dimensional cone beam computed tomography (CBCT) data, an early prognosis was facilitated by monitoring changes in lesion volume. Various treatment predictors-including sex, type of treatment, lesion size, preoperative pain, jaw, type of teeth involved, sealer extrusion, and the number of root canals-were meticulously analyzed. The evaluation of post-treatment outcomes leveraged both clinical observations and radiographic data collected during the follow-up periods. The Kruskal‒Wallis test and one-way ANOVA were also conducted to determine the independent factors influencing treatment outcomes. A significance level of 5% was established. Results: Thirty-five teeth from 35 patients with a median age of 28 years (range 24-34) were treated; the median follow-up duration was 19 months (range 12-26). The overall success rate was 91.4%, with a median lesion reduction of 77.0% (range 54.2-96.4%) at 6 months. Patients under 30 years of age exhibited a significantly greater success rate than older patients did (100.0% vs. 80.0%, p = 0.037). Other factors, such as sex, jaw, treatment type, preoperative pain, cyst size, tooth location, sealer extrusion, and the number of roots, did not significantly impact treatment outcomes. Conclusions: Despite limitations related to the observational case-series study design and relatively small sample size, our findings suggest that utilizing the ANPI in the NSRCT for LCPLs may hold promise. The notably higher success rate in patients younger than 30 years is worth noting.
MeSH term(s)	Humans ; Young Adult ; Adult ; Root Canal Therapy/methods ; Treatment Outcome ; Prognosis ; Cone-Beam Computed Tomography/methods ; Cysts ; Pain ; Periapical Periodontitis/therapy
Language	English
Publishing date	2024-03-15
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-024-04110-2
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Book ; Thesis: Pituitary adenylate cyclase activating peptide

Zhang, Yanzhen

a neuropeptide in the sensory nervous system

1996

Author's details	av Yanzhen Zhang
Language	English
Size	Getr. Zählung : Ill., graph. Darst.
Publishing country	Sweden
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Lund, Univ., Diss., 1996
HBZ-ID	HT007286594
ISBN	91-628-2160-1 ; 978-91-628-2160-9
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
96 E 1906	order for loan	Magazin

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Article: Identification of Differentially Expressed Long Noncoding RNAs as Functional Biomarkers and Construction of Function Enrichment Network in Oral Squamous Cell Carcinoma.

Xiao, Fang / Wang, Ke / Chen, Yaojun / Zhang, Yanzhen

publication RETRACTED

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 1572249

Abstract: Objective: This study aims to find the novel lncRNAs closely related to the progression of oral squamous cell carcinoma (OSCC) by comprehensively analyzing microarray.: Methods: Chip dataset GSE84805 was downloaded from the Gene Expression Omnibus ( ... ...

Abstract	Objective: This study aims to find the novel lncRNAs closely related to the progression of oral squamous cell carcinoma (OSCC) by comprehensively analyzing microarray. Methods: Chip dataset GSE84805 was downloaded from the Gene Expression Omnibus (GEO) database, lncRNA expression profiles of OSCC and paracancerous tissue were obtained, probes sequences reannotation was conducted, and differentially expressed lncRNAs (DELs) and differentially expressed genes (DEGs) were identified. Finally, these data were analyzed by constructing the lncRNA-function enrichment network. Results: We found that 465 lncRNAs are differentially expressed consisting of 193 upregulated lncRNAs and 272 downregulated lncRNAs. Meanwhile, 811 DEGs were identified with 498 upregulated genes and 313 downregulated genes. Analysis of the lncRNA-function enrichment network showed that these aberrant lncRNAs may be related to focal adhesion, inflammatory response pathway, cell cycle, matrix metalloproteinases, and other biological functions. Also, we found that some key lncRNAs such as LINC00152 and HOXA11-AS have been shown to play an important role in tumor proliferation and migration. Conclusion: The key lncRNAs may serve as potential molecular markers or therapeutic targets in OSCC formation and development. It can also help us to understand the molecular mechanism of occurrence and development in OSCC.
Language	English
Publishing date	2022-06-25
Publishing country	United States
Document type	Journal Article ; Retracted Publication
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/1572249
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Zs.A 5995: Show issues

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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
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Article: Psychological flexibility and COVID-19 burnout in Chinese college students: A moderated mediation model.

Ye, Baojuan / Chen, Xun / Zhang, Yanzhen / Yang, Qiang

Journal of contextual behavioral science

2022 Volume 24, Page(s) 126–133

Abstract: Few studies have examined factors that might explain or affect the relationship between psychological flexibility and university students' COVID-19 burnout. The present study tested a moderated mediation model with perceived COVID-19 stress as the ... ...

Abstract	Few studies have examined factors that might explain or affect the relationship between psychological flexibility and university students' COVID-19 burnout. The present study tested a moderated mediation model with perceived COVID-19 stress as the mediator and social support, a moderator, among 2377 Chinese college students. After controlling for gender, age, family location, and year of study (freshmen, sophomores, juniors, seniors), psychological flexibility was significantly associated with COVID-19 burnout, and this link was mediated by perceived COVID-19 stress. Social support buffered the adverse effects of perceived COVID-19 stress on psychological flexibility, as well as the correlation between perceived COVID-19 stress and burnout.
Language	English
Publishing date	2022-04-18
Publishing country	Netherlands
Document type	Journal Article
ISSN	2212-1447
ISSN	2212-1447
DOI	10.1016/j.jcbs.2022.04.003
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Article: Clinical Effects of Photofunctionalization on Implant Stability and Marginal Bone Loss: Systematic Review and Meta-Analysis.

Lang, Xinrui / Qiao, Bo / Ge, Ziyu / Yan, Jiahui / Zhang, Yanzhen

Journal of clinical medicine

2022 Volume 11, Issue 23

Abstract: Background: Several clinical trials have recently been conducted to elucidate the effectiveness of photofunctionalization. The aim of this review was to systematically analyze the clinical effects of photofunctionalization on implant stability and ... ...

Abstract	Background: Several clinical trials have recently been conducted to elucidate the effectiveness of photofunctionalization. The aim of this review was to systematically analyze the clinical effects of photofunctionalization on implant stability and marginal bone loss (MBL). Methods: An electronic search in four databases and a manual search were conducted in September 2022. Randomized controlled trials (RCTs), clinical controlled trials (CCTs), and cohort and case-control studies evaluating the effects of photofunctionalization on implant stability or marginal bone loss (MBL) in humans were included. The methodological quality assessment using RoB 2.0 and the ROBINS-I tool was performed based on different study designs. Results: Seven studies were included for a qualitative analysis, and five of them were chosen for a meta-analysis. The meta-analysis revealed that photofunctionalization significantly improved the stability of the implant 2 months after implantation ( Conclusions: Based on the positive effect of photofunctionalization on the rate of establishing implant stability, photofunctionalization may provide an effective and practical strategy to achieve faster osseointegration and reduce the overall healing time. Photofunctionalization appears to improve the implant stability. However, the clinical effect of photofunctionalization on MBL remains unclear due to the shortage of available studies.
Language	English
Publishing date	2022-11-28
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11237042
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Article: Perceived parental support and college students' depressive symptoms during the COVID-19 pandemic: The mediating roles of emotion regulation strategies and resilience.

Ye, Baojuan / Zhao, Shunying / Zeng, Yadi / Chen, Chuansheng / Zhang, Yanzhen

Current psychology (New Brunswick, N.J.)

2022 , Page(s) 1–12

Abstract: The current study examined the mediating roles of emotion regulation strategies (i.e., cognitive reappraisal and expressive suppression) and resilience in the relationship between perceived parental support and depressive symptoms among college students ... ...

Abstract	The current study examined the mediating roles of emotion regulation strategies (i.e., cognitive reappraisal and expressive suppression) and resilience in the relationship between perceived parental support and depressive symptoms among college students during the first wave of the COVID-19 pandemic in China. A large sample of Chinese college students (
Language	English
Publishing date	2022-04-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2021598-8
ISSN	1936-4733 ; 1046-1310
ISSN (online)	1936-4733
ISSN	1046-1310
DOI	10.1007/s12144-022-03049-3
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