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Book ; Online: Performance-Related Material Properties of Asphalt Mixture Components

Ling, Meng / Zhang, Yao / Ding, Haibo / Chen, Yu

2023

Keywords	Technology: general issues ; History of engineering & technology ; Transport technology & trades ; asphalt performance grading ; thermal cracking ; fatigue ; phase angle ; creep rate ; failure strain ; asphalt mixture ; fatigue performance ; rolling load ; laboratory test ; device ; geometry ; mechanical load ; thermal load ; numerical simulation ; cracking ; flow-rutting ; axial and lateral deformation ; optical fiber Bragg grating ; asphalt binder ; fractions composition ; mechanical property ; rheological properties ; asphalt colloidal structure ; asphaltene ; asphalt mortar ; dynamic mechanical analysis ; phase transition ; high- and low-temperature performance ; back calculation of modulus ; Falling Weight Deflectometer (FWD) ; firefly optimization algorithm ; RIOHTrack ; tire-pavement contact ; texture information identification ; numerical modeling ; fluid hydrodynamic lubrication theory ; orthogonal experimental design ; peak adhesion coefficient ; molecular weight distribution ; branching of wax ; moisture sensitivity ; surface free-energy ; binder bond strength ; warm mix additive ; waste polypropylene plastic ; pyrolysis ; PP wax ; modified asphalt ; epoxy asphalt ; TG-MS ; cone calorimeter test ; pyrolysis combustion characteristics ; phase transformation ; characteristic temperature ; load ; environment ; hot rejuvenated asphalt mixtures ; Hamburg wheel tracking test ; moisture damage ; economic benefit ; fiber ; aging ; oxidation ; wax ; nuclear magnetic resonance ; gas chromatography ; plastic and basalt fiber composite modifier ; urban bus lane ; pavement performance ; statics analysis ; load transfer mechanism ; testing method ; contact force ; force chain
Language	English
Size	1 electronic resource (314 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030377896
ISBN	9783036574264 ; 3036574263
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: [Comparison of the ability of four different kinds of nickel-titanium instruments to prepare simulated resin to simulate curved root canal forming].

Liang, Zhao-Huang / Zhang, Yao

Shanghai kou qiang yi xue = Shanghai journal of stomatology

2024 Volume 33, Issue 1, Page(s) 54–58

Abstract: Purpose: To compare the forming ability of four kinds of nickel-titanium instrument preparation resin for simulated curved root canal.: Methods: A total of 40 single bend resin simulated root canals were randomly divided into 4 groups with 10 in each ...

Abstract	Purpose: To compare the forming ability of four kinds of nickel-titanium instrument preparation resin for simulated curved root canal. Methods: A total of 40 single bend resin simulated root canals were randomly divided into 4 groups with 10 in each group. Four kinds of nickel-titanium instruments (ProTaper, HyFlex EDM, WaveOne Gold and Reciproc Blue) were used for root canal preparation, and divided into group A, group B, group C and group D. The preparation time of the four groups was compared, the root canal images before and after preparation were analyzed by computer image analysis software, and the changes of the preparation time, curvature and curvature radius of the four groups were recorded. With the root tip as the center of the circle, the radius of 1-10 mm was selected as concentric circle arcs. The detection points were overlapping root canal intersection points. The resin removal amount and center positioning force of the inner and outer walls of the root canal at different detection points were recorded. Statistical analysis was performed with SPSS 20.0 software package. Results: The root canal preparation time in group A was significant longer than that in group B, C and D(P＜0.05), but there was no significant difference in the curvature and curvature radius of the root canal among the four groups (P＞0.05). The removal amount of resin from the root canal wall in group C was significant lower than that in group A, B and D (P＜0.05) when the distance from the detection point to the apical foramina was 5, 6, 8, 9 and 10 mm, respectively. The removal amount of resin from the outer wall of the root canal in group C was significant lower than that in group A, B and D (P＜0.05) when the distance from the detection point to the apical foramina was 5, 6, 7, 9 and 10 mm, respectively. The root tip offset of group A from the detection point to the apical hole of 1, 2, 3, 4, 6, 7, 8, 9 and 10 mm was significant greater than that of group B, C and D(P＜0.05). Conclusions: Among the four instruments, ProTaper has the largest apical deviation, HyFlex EDM, WaveOne Gold and Reciproc Blue have better ability of root canal forming.
MeSH term(s)	Dental Pulp Cavity ; Titanium ; Nickel ; Dental Instruments ; Root Canal Preparation/methods ; Equipment Design
Chemical Substances	titanium nickelide (12035-60-8) ; Titanium (D1JT611TNE) ; Nickel (7OV03QG267)
Language	Chinese
Publishing date	2024-04-06
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	2269714-7
ISSN	1006-7248
ISSN	1006-7248
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Mini-ALPPS-based multidisciplinary treatment leading to long-term survival in a patient with a large HCC: A case report.

Liu, Gao-Min / Zhang, Yao-Min

Frontiers in surgery

2023 Volume 9, Page(s) 920953

Abstract: Background: The future liver remnant (FLR) induced by stage I associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) in hepatocellular carcinoma (HCC) might be limited due to liver fibrosis/cirrhosis or incomplete liver ... ...

Abstract	Background: The future liver remnant (FLR) induced by stage I associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) in hepatocellular carcinoma (HCC) might be limited due to liver fibrosis/cirrhosis or incomplete liver parenchymal transection. Case presentation: A 51-year-old male with hepatitis B liver fibrosis was diagnosed with a large HCC (13.5 cm × 12.5 cm × 13.8 cm). The FLR of the patient was insufficient to permit one-stage tumor resection. Therefore, the two-stage ALPPS surgery was planned. Stage I ALPPS was performed with incomplete liver parenchymal transection due to bleeding (which is why we called it Mini-ALPPS). On postoperative day (POD) 18, CT revealed that the FLR hypertrophy was poor. The FLR/standard liver volume (SLV) had only increased from 22.00% to 34.63%. Salvage transhepatic arterial chemoembolization (TACE) was performed on POD 22 days to control possible tumor progression during the waiting period and to further facilitate FLR growth. About 16 days later, a CT reassessment of FLR revealed a 42.5% FLR/SLV. A right hepatectomy was then uneventfully performed. Although HCC recurred after 586 days, the patient survived for more than 1,920 days after stage II ALPPS. Discussion: Damage control during a difficult conventional stage I ALPPS was important. TACE during the interstage and postoperative periods of this Mini-ALPPS was safe and beneficial. A multidisciplinary based on Mini-ALPPS treatment could provide patients long-term survival; however, Mini-ALPPS should not be selected as the primary solution for such patients today, as some other minimally invasive and effective strategies are available.
Language	English
Publishing date	2023-01-24
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2773823-1
ISSN	2296-875X
ISSN	2296-875X
DOI	10.3389/fsurg.2022.920953
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Barriers to, and facilitators of, eHealth utilisation by parents of high-risk newborn infants in the NICU: a scoping review protocol.

Zhang, Yao / Johnston, Linda

BMJ open

2023 Volume 13, Issue 5, Page(s) e068759

Abstract: Introduction: Parental presence in the neonatal intensive care unit (NICU) has been demonstrated to enhance infant growth and development, reduce parental anxiety and stress and strengthen parent-infant bonding. Since eHealth technology emerged, ... ...

Abstract	Introduction: Parental presence in the neonatal intensive care unit (NICU) has been demonstrated to enhance infant growth and development, reduce parental anxiety and stress and strengthen parent-infant bonding. Since eHealth technology emerged, research on its utilisation in NICUs has risen substantially. There is some evidence that incorporating such technologies in the NICU can reduce parental stress and enhance parent confidence in caring for their infant.Several countries, including China, restrict parental attendance in NICUs, citing infection control challenges, issues of privacy and confidentiality and perceived additional workload for healthcare professionals. Due to COVID-19 pandemic-related shortages of personal protective equipment and uncertain mode of transmission, many NICUs around the world closed to parental visiting and engagement in neonatal care.There is anecdotal evidence that, given pandemic-related restrictions, eHealth technologies, have increasingly been used in NICUs as a potential substitute for in-person parental presence.However, the constraints and enablers of technologies in these situations have not been exhaustively examined. This scoping review aims to update the literature on eHealth technology utilisation in the NICU and to explore the literature on the challenges and facilitators of eHealth technology implementation to inform future research. Methods and analysis: The five-stage Arksey and O'Malley methodological framework and the Joanna Briggs Institute scoping review methodology will serve as the foundation for this scoping review. Eight databases will be searched for the relevant literature published between January 2000 and August 2022 in either English or Chinese. Grey literature will be manually searched. Data extraction and eligibility screening will be carried out by two impartial reviewers. There will be periods of both quantitative and qualitative analysis. Ethics and dissemination: Since all data and information will be taken from publicly accessible literature, ethical approval would not be necessary. A peer-reviewed publication will be published with the results of this scoping review. Trial registration number: This scoping review protocol was registered in Open Science Framework and can be found here: https://osf.io/AQV5P/.
MeSH term(s)	Infant, Newborn ; Humans ; Infant ; Intensive Care Units, Neonatal ; Pandemics ; COVID-19/epidemiology ; Parents ; Telemedicine ; Research Design ; Review Literature as Topic
Language	English
Publishing date	2023-05-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2022-068759
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Signal Pathways and Intestinal Flora through Trimethylamine N-oxide in Alzheimer's Disease.

Zhang, Yao / Jian, Wenxuan

Current protein & peptide science

2023 Volume 24, Issue 9, Page(s) 721–736

Abstract: The current studies show signs of progress in treating Alzheimer's disease (AD) with the "brain-gut axis." Restoring intestinal flora balance can alleviate neurodegeneration in the central nervous system. However, due to the complex mechanisms involved ... ...

Abstract	The current studies show signs of progress in treating Alzheimer's disease (AD) with the "brain-gut axis." Restoring intestinal flora balance can alleviate neurodegeneration in the central nervous system. However, due to the complex mechanisms involved in the brain-gut axis, the neuroprotective mechanism brought by intestinal flora has not been fully understood. Trimethylamine N-oxide (TMAO) is a microbiota-dependent metabolism production; TMAO has been proven to be a major risk factor for atherosclerosis, thrombosis, type II diabetes, and other diseases. Meanwhile, all the above diseases are associated with AD; thus, we speculate that TMAO and AD are also correlated. Microbiota, such as
Language	English
Publishing date	2023-07-18
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2045662-1
ISSN	1875-5550 ; 1389-2037
ISSN (online)	1875-5550
ISSN	1389-2037
DOI	10.2174/1389203724666230717125406
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Iridoschisis misdiagnosed as acute angle-closure glaucoma: a case report and literature review.

Wan, Huan / Zhang, Yao / Tang, Li

International journal of ophthalmology

2024 Volume 17, Issue 1, Page(s) 201–205

Language	English
Publishing date	2024-01-18
Publishing country	China
Document type	Journal Article
ZDB-ID	2663246-9
ISSN	2227-4898 ; 2222-3959
ISSN (online)	2227-4898
ISSN	2222-3959
DOI	10.18240/ijo.2024.01.25
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Predicting cell types with supervised contrastive learning on cells and their types.

Heryanto, Yusri Dwi / Zhang, Yao-Zhong / Imoto, Seiya

Scientific reports

2024 Volume 14, Issue 1, Page(s) 430

Abstract: Single-cell RNA-sequencing (scRNA-seq) is a powerful technique that provides high-resolution expression profiling of individual cells. It significantly advances our understanding of cellular diversity and function. Despite its potential, the analysis of ... ...

Abstract	Single-cell RNA-sequencing (scRNA-seq) is a powerful technique that provides high-resolution expression profiling of individual cells. It significantly advances our understanding of cellular diversity and function. Despite its potential, the analysis of scRNA-seq data poses considerable challenges related to multicollinearity, data imbalance, and batch effect. One of the pivotal tasks in single-cell data analysis is cell type annotation, which classifies cells into discrete types based on their gene expression profiles. In this work, we propose a novel modeling formalism for cell type annotation with a supervised contrastive learning method, named SCLSC (Supervised Contrastive Learning for Single Cell). Different from the previous usage of contrastive learning in single cell data analysis, we employed the contrastive learning for instance-type pairs instead of instance-instance pairs. More specifically, in the cell type annotation task, the contrastive learning is applied to learn cell and cell type representation that render cells of the same type to be clustered in the new embedding space. Through this approach, the knowledge derived from annotated cells is transferred to the feature representation for scRNA-seq data. The whole training process becomes more efficient when conducting contrastive learning for cell and their types. Our experiment results demonstrate that the proposed SCLSC method consistently achieves superior accuracy in predicting cell types compared to five state-of-the-art methods. SCLSC also performs well in identifying cell types in different batch groups. The simplicity of our method allows for scalability, making it suitable for analyzing datasets with a large number of cells. In a real-world application of SCLSC to monitor the dynamics of immune cell subpopulations over time, SCLSC demonstrates a capability to discriminate cell subtypes of CD19+ B cells that were not present in the training dataset.
MeSH term(s)	Learning ; Knowledge ; Single-Cell Analysis ; Gene Expression Profiling
Language	English
Publishing date	2024-01-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-50185-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The nonlinear mechanics of highly extensible plant epidermal cell walls.

Yu, Jingyi / Zhang, Yao / Cosgrove, Daniel J

Proceedings of the National Academy of Sciences of the United States of America

2024 Volume 121, Issue 2, Page(s) e2316396121

Abstract: Plant epidermal cell walls maintain the mechanical integrity of plants and restrict organ growth. Mechanical analyses can give insights into wall structure and are inputs for mechanobiology models of plant growth. To better understand the intrinsic ... ...

Abstract	Plant epidermal cell walls maintain the mechanical integrity of plants and restrict organ growth. Mechanical analyses can give insights into wall structure and are inputs for mechanobiology models of plant growth. To better understand the intrinsic mechanics of epidermal cell walls and how they may accommodate large deformations during growth, we analyzed a geometrically simple material, onion epidermal strips consisting of only the outer (periclinal) cell wall, ~7 μm thick. With uniaxial stretching by >40%, the wall showed complex three-phase stress-strain responses while cyclic stretching revealed reversible and irreversible deformations and elastic hysteresis. Stretching at varying strain rates and temperatures indicated the wall behaved more like a network of flexible cellulose fibers capable of sliding than a viscoelastic composite with pectin viscosity. We developed an analytic framework to quantify nonlinear wall mechanics in terms of stiffness, deformation, and energy dissipation, finding that the wall stretches by combined elastic and plastic deformation without compromising its stiffness. We also analyzed mechanical changes in slightly dehydrated walls. Their extension became stiffer and more irreversible, highlighting the influence of water on cellulose stiffness and sliding. This study offers insights into the structure and deformation modes of primary cell walls and presents a framework that is also applicable to tissues and whole organs.
MeSH term(s)	Cellulose/chemistry ; Cell Wall/chemistry ; Cell Membrane ; Pectins ; Plant Epidermis
Chemical Substances	Cellulose (9004-34-6) ; Pectins (89NA02M4RX)
Language	English
Publishing date	2024-01-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2316396121
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effect of iron chelation therapy on EPO-STAT5 signalling pathway and EPO resistance in iron-overloaded low-risk myelodysplastic syndrome patients.

Zhang, Yao

Hematology (Amsterdam, Netherlands)

2019 Volume 25, Issue 1, Page(s) 1–10

Abstract: Objectives: Background/aims: ...

Abstract	Objectives: Background/aims:
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Chelation Therapy ; Erythropoietin/metabolism ; Female ; Hematinics/therapeutic use ; Humans ; Iron Chelating Agents/therapeutic use ; Iron Overload/complications ; Iron Overload/drug therapy ; Iron Overload/metabolism ; Male ; Middle Aged ; Myelodysplastic Syndromes/complications ; Myelodysplastic Syndromes/drug therapy ; Myelodysplastic Syndromes/metabolism ; STAT5 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Tumor Suppressor Proteins/metabolism
Chemical Substances	Hematinics ; Iron Chelating Agents ; STAT5 Transcription Factor ; STAT5A protein, human ; Tumor Suppressor Proteins ; Erythropoietin (11096-26-7)
Language	English
Publishing date	2019-12-06
Publishing country	England
Document type	Journal Article
ZDB-ID	1341428-8
ISSN	1607-8454 ; 1024-5332 ; 1024-5340
ISSN (online)	1607-8454
ISSN	1024-5332 ; 1024-5340
DOI	10.1080/16078454.2019.1700330
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Article ; Online: Enhancer-MDLF: a novel deep learning framework for identifying cell-specific enhancers.

Zhang, Yao / Zhang, Pengyu / Wu, Hao

Briefings in bioinformatics

2024 Volume 25, Issue 2

Abstract: Enhancers, noncoding DNA fragments, play a pivotal role in gene regulation, facilitating gene transcription. Identifying enhancers is crucial for understanding genomic regulatory mechanisms, pinpointing key elements and investigating networks governing ... ...

Abstract	Enhancers, noncoding DNA fragments, play a pivotal role in gene regulation, facilitating gene transcription. Identifying enhancers is crucial for understanding genomic regulatory mechanisms, pinpointing key elements and investigating networks governing gene expression and disease-related mechanisms. Existing enhancer identification methods exhibit limitations, prompting the development of our novel multi-input deep learning framework, termed Enhancer-MDLF. Experimental results illustrate that Enhancer-MDLF outperforms the previous method, Enhancer-IF, across eight distinct human cell lines and exhibits superior performance on generic enhancer datasets and enhancer-promoter datasets, affirming the robustness of Enhancer-MDLF. Additionally, we introduce transfer learning to provide an effective and potential solution to address the prediction challenges posed by enhancer specificity. Furthermore, we utilize model interpretation to identify transcription factor binding site motifs that may be associated with enhancer regions, with important implications for facilitating the study of enhancer regulatory mechanisms. The source code is openly accessible at https://github.com/HaoWuLab-Bioinformatics/Enhancer-MDLF.
MeSH term(s)	Humans ; Enhancer Elements, Genetic ; Deep Learning ; Genomics/methods ; Gene Expression Regulation ; Promoter Regions, Genetic
Language	English
Publishing date	2024-03-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2068142-2
ISSN	1477-4054 ; 1467-5463
ISSN (online)	1477-4054
ISSN	1467-5463
DOI	10.1093/bib/bbae083
Database	MEDical Literature Analysis and Retrieval System OnLINE

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