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Article: Effects of Massa Medicata Fermentata on the intestinal pathogenic flagella bacteria and visceral hypersensitivity in rats with irritable bowel syndrome.

Zhuang, Zhaomeng / Huang, Chen / Zhang, Yiguang / Lv, Bin

2022 Volume 13, Page(s) 1039804

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2022-11-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564217-0
ISSN	1664-042X
ISSN	1664-042X
DOI	10.3389/fphys.2022.1039804
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Association of Helicobacter pylori enrichment in colorectal adenoma tissue on clinical and pathological features of adenoma.

Zhuang, Zhaomeng / Yu, Bingqu / Xie, Min / Zhang, Yiguang / Lv, Bin

Clinics and research in hepatology and gastroenterology

2022 Volume 46, Issue 6, Page(s) 101961

Abstract: Objective: To investigate the enrichment of Helicobacter pylori (Hp) in adenoma tissue of patients with colorectal adenoma, and analyze the correlation between the enrichment and the clinical and pathological characteristics of colorectal adenoma.: ... ...

Abstract	Objective: To investigate the enrichment of Helicobacter pylori (Hp) in adenoma tissue of patients with colorectal adenoma, and analyze the correlation between the enrichment and the clinical and pathological characteristics of colorectal adenoma. Methods: The data of 1,622 patients undergoing gastrointestinal endoscopy in the Endoscopy Center of Wenzhou Integrated Traditional Chinese and Western Medicine Hospital affiliated to Zhejiang University of Traditional Chinese Medicine from January 2019 to June 2021 were retrospectively collected. The general data, gastric Hp infection, clinical and pathological features of colorectal adenoma, methylene blue staining of adenoma Hp, immunohistochemistry of adenoma Hp and immunofluorescence staining of adenoma TLR5 protein. were compared between the colorectal adenoma group (743 cases) and the control group (879 cases). Results: There were 361 gastric Hp positive cases in the colorectal adenoma group, with a positive rate of 48.59%, and 331 gastric Hp positive cases in the control group, with a positive rate of 37.66%, and the difference was statistically significant (P < 0.001). Gastric Hp infection significantly correlates with the Hp enrichment in colorectal adenomas (OR: 28.449; 95%CI: 18.188-44.500; P < 0.001). Moreover, we found that Hp enrichment in colorectal adenomas was correlated with the diameter, pathological type, and malignancy of adenoma (OR: 3.536; 3.652; 2.833; all P < 0.001). Expression TLR5 protein was also increased in Hp-enriched adenoma tissue. Conclusion: There is a correlation between gastric Hp infection and intestinal Hp enrichment. The intestinal Hp enrichment significantly correlates with the clinical and pathological characteristics of colorectal adenomas, and its tumor-promoting effect may be related to the up-regulation of mucosal TLR5 expression.
MeSH term(s)	Adenoma/pathology ; Colorectal Neoplasms/pathology ; Gastric Mucosa/pathology ; Helicobacter Infections/complications ; Helicobacter Infections/metabolism ; Helicobacter pylori ; Humans ; Retrospective Studies ; Toll-Like Receptor 5
Chemical Substances	Toll-Like Receptor 5
Language	English
Publishing date	2022-05-27
Publishing country	France
Document type	Journal Article
ZDB-ID	2594333-9
ISSN	2210-741X ; 2210-7401
ISSN (online)	2210-741X
ISSN	2210-7401
DOI	10.1016/j.clinre.2022.101961
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The effect of nasopharyngeal ventilation on the detection rate of colorectal polyps in two hundred middle-aged and elderly overweight patients.

Zhuang, Zhaomeng / Zheng, Juanhong / Xie, Min / Zhang, Yiguang

International journal of clinical practice

2021 Volume 75, Issue 11, Page(s) e14884

MeSH term(s)	Aged ; Colonic Polyps ; Colorectal Neoplasms ; Humans ; Middle Aged ; Overweight
Language	English
Publishing date	2021-10-20
Publishing country	England
Document type	Letter
ZDB-ID	1386246-7
ISSN	1742-1241 ; 1368-5031
ISSN (online)	1742-1241
ISSN	1368-5031
DOI	10.1111/ijcp.14884
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Ua VI Zs.301: Show issues

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Book ; Online: Node Attribute Prediction on Multilayer Networks with Weighted and Directed Edges

Zhang, Yiguang / Altenburger, Kristen / Zhang, Poppy / Okano, Tsutomu / Hill, Shawndra

2023

Abstract: With the rapid development of digital platforms, users can now interact in endless ways from writing business reviews and comments to sharing information with their friends and followers. As a result, organizations have numerous digital social networks ... ...

Abstract	With the rapid development of digital platforms, users can now interact in endless ways from writing business reviews and comments to sharing information with their friends and followers. As a result, organizations have numerous digital social networks available for graph learning problems with little guidance on how to select the right graph or how to combine multiple edge types. In this paper, we first describe the types of user-to-user networks available across the Facebook (FB) and Instagram (IG) platforms. We observe minimal edge overlap between these networks, indicating users are exhibiting different behaviors and interaction patterns between platforms. We then compare predictive performance metrics across various node attribute prediction tasks for an ads click prediction task on Facebook and for a publicly available dataset from the Open Graph Benchmark. We adapt an existing node attribute prediction method for binary prediction, LINK-Naive Bayes, to account for both edge direction and weights on single-layer networks. We observe meaningful predictive performance gains when incorporating edge direction and weight. We then introduce an approach called MultiLayerLINK-NaiveBayes that can combine multiple network layers during training and observe superior performance over the single-layer results. Ultimately, whether edge direction, edge weights, and multi-layers are practically useful will depend on the particular setting. Our approach enables practitioners to quickly combine multiple layers and additional edge information such as direction or weight.
Keywords	Computer Science - Social and Information Networks
Subject code	006
Publishing date	2023-05-17
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Association of Helicobacter pylori enrichment in colorectal adenoma tissue on clinical and pathological features of adenoma

Zhuang, Zhaomeng / Yu, Bingqu / xie, Min / zhang, Yiguang / Lv, Bin

Clinics and research in hepatology and gastroenterology. 2022 May 16,

2022

Abstract: To investigate the enrichment of Helicobacter pylori (Hp) in adenoma tissue of patients with colorectal adenoma, and analyze the correlation between the enrichment and the clinical and pathological characteristics of colorectal adenoma. The data of 1,622 ...

Abstract	To investigate the enrichment of Helicobacter pylori (Hp) in adenoma tissue of patients with colorectal adenoma, and analyze the correlation between the enrichment and the clinical and pathological characteristics of colorectal adenoma. The data of 1,622 patients undergoing gastrointestinal endoscopy in the Endoscopy Center of Wenzhou Integrated Traditional Chinese and Western Medicine Hospital affiliated to Zhejiang University of Traditional Chinese Medicine from January 2019 to June 2021 were retrospectively collected. The general data, gastric Hp infection, clinical and pathological features of colorectal adenoma, methylene blue staining of adenoma Hp, immunohistochemistry of adenoma Hp and immunofluorescence staining of adenoma TLR5 protein. were compared between the colorectal adenoma group (743 cases) and the control group (879 cases). There were 361 gastric Hp positive cases in the colorectal adenoma group, with a positive rate of 48.59%, and 331 gastric Hp positive cases in the control group, with a positive rate of 37.66%, and the difference was statistically significant (P < 0.001). Gastric Hp infection significantly correlates with the Hp enrichment in colorectal adenomas (OR: 28.449; 95%CI: 18.188-44.500; P < 0.001). Moreover, we found that Hp enrichment in colorectal adenomas was correlated with the diameter, pathological type, and malignancy of adenoma (OR: 3.536; 3.652; 2.833; all P < 0.001). Expression TLR5 protein was also increased in Hp-enriched adenoma tissue. There is a correlation between gastric Hp infection and intestinal Hp enrichment. The intestinal Hp enrichment significantly correlates with the clinical and pathological characteristics of colorectal adenomas, and its tumor-promoting effect may be related to the up-regulation of mucosal TLR5 expression.
Keywords	Helicobacter pylori ; Oriental traditional medicine ; adenoma ; fluorescent antibody technique ; gastrointestinal endoscopy ; hospitals ; immunohistochemistry ; intestines ; methylene blue ; research ; China
Language	English
Dates of publication	2022-0516
Publishing place	Elsevier Masson SAS
Document type	Article
Note	Pre-press version
ZDB-ID	2594333-9
ISSN	2210-741X ; 2210-7401
ISSN (online)	2210-741X
ISSN	2210-7401
DOI	10.1016/j.clinre.2022.101961
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Two machine learning approaches for predicting cyanobacteria abundance in aquaculture ponds.

Zhang, Man / Zhang, Yiguang / Yu, Songyan / Gao, Yunni / Dong, Jing / Zhu, Weixia / Wang, Xianfeng / Li, Xuejun / Li, Juntao / Xiong, Jiandong

Ecotoxicology and environmental safety

2023 Volume 258, Page(s) 114944

Abstract: Cyanobacteria blooms in aquaculture ponds harm the harvesting of aquatic animals and threaten human health. Therefore, it is crucial to identify key drivers and develop methods to predict cyanobacteria blooms in aquaculture water management. In this ... ...

Abstract	Cyanobacteria blooms in aquaculture ponds harm the harvesting of aquatic animals and threaten human health. Therefore, it is crucial to identify key drivers and develop methods to predict cyanobacteria blooms in aquaculture water management. In this study, we analyzed monitoring data from 331 aquaculture ponds in central China and developed two machine learning models - the least absolute shrinkage and selection operator (LASSO) regression model and the random forest (RF) model - to predict cyanobacterial abundance by identifying the key drivers. Simulation results demonstrated that both machine learning models are feasible for predicting cyanobacterial abundance in aquaculture ponds. The LASSO model (R
MeSH term(s)	Animals ; Humans ; Ponds/microbiology ; Environmental Monitoring/methods ; Cyanobacteria ; Water ; Aquaculture ; Carbon
Chemical Substances	Water (059QF0KO0R) ; Carbon (7440-44-0)
Language	English
Publishing date	2023-04-27
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	436536-7
ISSN	1090-2414 ; 0147-6513
ISSN (online)	1090-2414
ISSN	0147-6513
DOI	10.1016/j.ecoenv.2023.114944
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Zs.A 1418: Show issues

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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Book ; Online: Chasm in Hegemony

Zhang, Yiguang / Han, Jessy Xinyi / Mahajan, Ilica / Bengani, Priyanjana / Chaintreau, Augustin

Explaining and Reproducing Disparities in Homophilous Networks

2021

Abstract: In networks with a minority and a majority community, it is well-studied that minorities are under-represented at the top of the social hierarchy. However, researchers are less clear about the representation of minorities from the lower levels of the ... ...

Abstract	In networks with a minority and a majority community, it is well-studied that minorities are under-represented at the top of the social hierarchy. However, researchers are less clear about the representation of minorities from the lower levels of the hierarchy, where other disadvantages or vulnerabilities may exist. We offer a more complete picture of social disparities at each social level with empirical evidence that the minority representation exhibits two opposite phases: at the higher rungs of the social ladder, the representation of the minority community decreases; but, lower in the ladder, which is more populous, as you ascend, the representation of the minority community improves. We refer to this opposing phenomenon between the upper-level and lower-level as the \emph{chasm effect}. Previous models of network growth with homophily fail to detect and explain the presence of this chasm effect. We analyze the interactions among a few well-observed network-growing mechanisms with a simple model to reveal the sufficient and necessary conditions for both phases in the chasm effect to occur. By generalizing the simple model naturally, we present a complete bi-affiliation bipartite network-growth model that could successfully capture disparities at all social levels and reproduce real social networks. Finally, we illustrate that addressing the chasm effect can create fairer systems with two applications in advertisement and fact-checks, thereby demonstrating the potential impact of the chasm effect on the future research of minority-majority disparities and fair algorithms.
Keywords	Computer Science - Social and Information Networks
Subject code	300
Publishing date	2021-02-23
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: [Analysis on formula raw materials application of health food containing Gardeniae fructus].

Zhang, Yi-guang / Tang, Shi-huan / Jia, Qiang / Meng, Fan-yun

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

2014 Volume 39, Issue 22, Page(s) 4470–4474

Abstract: In this article we built formula database of health food containing Gardeniae Fructus with Traditional Chinese Medicine Inheritance Support System (V2.0). And on this basis, use data mining method such as association rules of the software, to analyze ... ...

Abstract	In this article we built formula database of health food containing Gardeniae Fructus with Traditional Chinese Medicine Inheritance Support System (V2.0). And on this basis, use data mining method such as association rules of the software, to analyze commonly used formula raw materials or materials combination of formula containing Gardeniae Fructus and raw material application having assisted function formula to protect chemical liver injury. The result shows that of the 71 health food formulas containing Gardeniae Fructus, most used materials are Gardeniae Fructus, Lycii Fructus, Angelica Sinensis Radix, Poria and so on. Commonly used materials combination mostly are Gardeniae Fructus and Lycii Fructus, Gardeniae Fructus and Angelica Sinensis Radix, Gardeniae Fructus and Poria, Gardeniae Fructus and Paeonia. There are nearly 18 healthcare functions of the health food containing Gardeniae Fructus, and most of these are assisted functions to protect chemical liver injury, and then immune modulating function. Of 23 formulas containing Gardeniae Fructus having assisted function formula to protect chemical liver injury, Gardeniae Fructus usually combined with traditional Chinese medicine which nourishs blood and liver such as Pueraria, Lycii Fructus, Hawthorn, Paeonia and Turnjujube. Analyzing formula raw materials application of health food containing Gardeniae Fructus contributes a lot to the further development and utilization.
MeSH term(s)	Chemical and Drug Induced Liver Injury/drug therapy ; Data Mining/methods ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Food, Organic ; Fruit/chemistry ; Gardenia/chemistry ; Medicine, Chinese Traditional/methods
Chemical Substances	Drugs, Chinese Herbal
Language	Chinese
Publishing date	2014-11
Publishing country	China
Document type	Journal Article
ZDB-ID	1004649-5
ISSN	1001-5302 ; 0254-0029
ISSN	1001-5302 ; 0254-0029
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 3056: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Entropy analysis reveals a simple linear relation between laser speckle and blood flow.

Miao, Peng / Chao, Zhen / Zhang, Yiguang / Li, Nan / Thakor, Nitish V

Optics letters

2014 Volume 39, Issue 13, Page(s) 3907–3910

Abstract: Dynamic laser speckles contain motion information of scattering particles which can be estimated by laser speckle contrast analysis (LASCA). In this work, an entropy-based method was proposed to provide a more robust estimation of motion speed. An in ... ...

Abstract	Dynamic laser speckles contain motion information of scattering particles which can be estimated by laser speckle contrast analysis (LASCA). In this work, an entropy-based method was proposed to provide a more robust estimation of motion speed. An in vitro flow simulation experiment confirmed a simple linear relation between entropy, exposure time, and speed. A multimodality optical imaging setup is developed to validate the advantages of the entropy method based on laser speckle imaging, green light imaging, and fluorescence imaging. The entropy method overcomes traditional LASCA with less noisy interference, and extracts more visible and detailed vasculatures in vivo. Furthermore, the entropy method provides a more accurate estimation and a stable pattern of blood flow activations in the rat's somatosensory area under multitrial hand paw stimulations.
MeSH term(s)	Animals ; Blood Flow Velocity/physiology ; Cerebrovascular Circulation ; Contrast Media ; Entropy ; Female ; Hemorheology ; Interferometry ; Lasers ; Linear Models ; Models, Cardiovascular ; Optical Imaging ; Optical Phenomena ; Rats ; Rats, Sprague-Dawley ; Scattering, Radiation ; Somatosensory Cortex/blood supply
Chemical Substances	Contrast Media
Language	English
Publishing date	2014-07-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1539-4794
ISSN (online)	1539-4794
DOI	10.1364/OL.39.003907
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Chronic wide-field imaging of brain hemodynamics in behaving animals.

Miao, Peng / Zhang, Lingke / Li, Miao / Zhang, Yiguang / Feng, Shihan / Wang, Qihong / Thakor, Nitish V

Biomedical optics express

2016 Volume 8, Issue 1, Page(s) 436–445

Abstract: Chronically monitoring cerebral activities in awake and freely moving status is very important in physiological and pathological studies. We present a novel standalone micro-imager for monitoring the cerebral blood flow (CBF) and total hemoglobin (HbT) ... ...

Abstract	Chronically monitoring cerebral activities in awake and freely moving status is very important in physiological and pathological studies. We present a novel standalone micro-imager for monitoring the cerebral blood flow (CBF) and total hemoglobin (HbT) activities in freely moving animals using the laser speckle contrast imaging (LSCI) and optical intrinsic signal (OIS) methods. A new cranial window method, using contact lens and wide field optics, is also proposed to achieve the chronic and wide-field imaging of rat's cerebral cortex. The hemodynamic activities of rats' cortex were measured for the first time without restriction of cables or fibers in awake and behaving animals. Chronic imaging showed the increase of CBF and HbT in motor cortex when the rats were climbing on the cage wall. Interestingly, the CBF activation of supplying vessel was smaller than that of parenchyma. Furthermore, after the climbing, CBF demonstrated fully return to the baseline while HbT showed a delayed recovery. The standalone micro-imager technology provides new possibilities of brain imaging in cognitive neuroscience studies.
Language	English
Publishing date	2016-12-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.8.000436
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