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  1. Article: The state-of-art polyurethane nanoparticles for drug delivery applications.

    Song, Wencong / Muhammad, Saz / Dang, Shanxing / Ou, Xingyan / Fang, Xingzi / Zhang, Yinghe / Huang, Lihe / Guo, Bing / Du, XueLian

    Frontiers in chemistry

    2024  Volume 12, Page(s) 1378324

    Abstract: Nowadays, polyurethanes (PUs) stand out as a promising option for drug delivery owing to their versatile properties. PUs have garnered significant attention in the biomedical sector and are extensively employed in diverse forms, including bulk devices, ... ...

    Abstract Nowadays, polyurethanes (PUs) stand out as a promising option for drug delivery owing to their versatile properties. PUs have garnered significant attention in the biomedical sector and are extensively employed in diverse forms, including bulk devices, coatings, particles, and micelles. PUs are crucial in delivering various therapeutic agents such as antibiotics, anti-cancer medications, dermal treatments, and intravaginal rings. Effective drug release management is essential to ensure the intended therapeutic impact of PUs. Commercially available PU-based drug delivery products exemplify the adaptability of PUs in drug delivery, enabling researchers to tailor the polymer properties for specific drug release patterns. This review primarily focuses on the preparation of PU nanoparticles and their physiochemical properties for drug delivery applications, emphasizing how the formation of PUs affects the efficiency of drug delivery systems. Additionally, cutting-edge applications in drug delivery using PU nanoparticle systems, micelles, targeted, activatable, and fluorescence imaging-guided drug delivery applications are explored. Finally, the role of artificial intelligence and machine learning in drug design and delivery is discussed. The review concludes by addressing the challenges and providing perspectives on the future of PUs in drug delivery, aiming to inspire the design of more innovative solutions in this field.
    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2024.1378324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unveiling the future: Advancements in MRI imaging for neurodegenerative disorders.

    Du, Lixin / Roy, Shubham / Wang, Pan / Li, Zhigang / Qiu, Xiaoting / Zhang, Yinghe / Yuan, Jianpeng / Guo, Bing

    Ageing research reviews

    2024  Volume 95, Page(s) 102230

    Abstract: Neurodegenerative disorders represent a significant and growing global health challenge, necessitating continuous advancements in diagnostic tools for accurate and early detection. This work explores the recent progress in Magnetic Resonance Imaging (MRI) ...

    Abstract Neurodegenerative disorders represent a significant and growing global health challenge, necessitating continuous advancements in diagnostic tools for accurate and early detection. This work explores the recent progress in Magnetic Resonance Imaging (MRI) techniques and their application in the realm of neurodegenerative disorders. The introductory section provides a comprehensive overview of the study's background, significance, and objectives. Recognizing the current challenges associated with conventional MRI, the manuscript delves into advanced imaging techniques such as high-resolution structural imaging (HR-MRI), functional MRI (fMRI), diffusion tensor imaging (DTI), and positron emission tomography-MRI (PET-MRI) fusion. Each technique is critically examined regarding its potential to address theranostic limitations and contribute to a more nuanced understanding of the underlying pathology. A substantial portion of the work is dedicated to exploring the applications of advanced MRI in specific neurodegenerative disorders, including Parkinson's disease, Alzheimer's disease, Huntington's disease, and Amyotrophic Lateral Sclerosis (ALS). In addressing the future landscape, the manuscript examines technological advances, including the integration of machine learning and artificial intelligence in neuroimaging. The conclusion summarizes key findings, outlines implications for future research, and underscores the importance of these advancements in reshaping our understanding and approach to neurodegenerative disorders.
    MeSH term(s) Humans ; Diffusion Tensor Imaging/methods ; Artificial Intelligence ; Brain/pathology ; Magnetic Resonance Imaging/methods ; Neurodegenerative Diseases/pathology
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2075672-0
    ISSN 1872-9649 ; 1568-1637
    ISSN (online) 1872-9649
    ISSN 1568-1637
    DOI 10.1016/j.arr.2024.102230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Light-activatable and hyperthermia-sensitive "all-in-one" theranostics: NIR-II fluorescence imaging and chemo-photothermal therapy of subcutaneous glioblastoma by temperature-sensitive liposome-containing AIEgens and paclitaxel.

    Du, Lixin / Wang, Pan / Huang, Haiyan / Li, Menglong / Roy, Shubham / Zhang, Yinghe / Guo, Bing

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1343694

    Abstract: Nowadays, it is still quite difficult to combat glioblastoma, which is one of the most lethal cancers for human beings. Combinatory therapy, which could not only improve therapeutic efficacy and overcome multiple drug resistance but also decrease the ... ...

    Abstract Nowadays, it is still quite difficult to combat glioblastoma, which is one of the most lethal cancers for human beings. Combinatory therapy, which could not only improve therapeutic efficacy and overcome multiple drug resistance but also decrease the threshold therapeutic drug dosage and minimize side effects, would be an appealing candidate for glioblastoma treatment. Herein, we report fluorescence imaging in the second near-infrared window (NIR-II)-guided combinatory photothermal therapy (PTT) and chemotherapy of glioblastoma with a newly formulated nanomedicine termed
    Language English
    Publishing date 2023-12-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1343694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Enhancing the Mechanical Stability of 2D Fullerene with a Graphene Substrate and Encapsulation.

    Yu, Taotao / Li, Jianyu / Han, Mingjun / Zhang, Yinghe / Li, Haipeng / Peng, Qing / Tang, Ho-Kin

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 13

    Abstract: Recent advancements have led to the synthesis of novel monolayer 2D carbon structures, namely quasi-hexagonal-phase fullerene ( ... ...

    Abstract Recent advancements have led to the synthesis of novel monolayer 2D carbon structures, namely quasi-hexagonal-phase fullerene (qHPC
    Language English
    Publishing date 2023-06-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13131936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rechargeable and highly stable Mn metal batteries based on organic electrolyte.

    He, Xincheng / Li, Zipeng / Tang, Run / Chen, Yingying / Meng, Xin / Zheng, Feize / Zhang, Yinghe / Liu, Jun

    Chemical communications (Cambridge, England)

    2023  Volume 59, Issue 10, Page(s) 1337–1340

    Abstract: Mn metal batteries are rarely reported due to the lack of a stable electrolyte. Here, ... ...

    Abstract Mn metal batteries are rarely reported due to the lack of a stable electrolyte. Here, an
    Language English
    Publishing date 2023-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d2cc05808a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Designing strategies and enhancing mechanism for multicomponent high-entropy catalysts.

    Xu, Haitao / Jin, Zeyu / Zhang, Yinghe / Lin, Xi / Xie, Guoqiang / Liu, Xingjun / Qiu, Hua-Jun

    Chemical science

    2023  Volume 14, Issue 4, Page(s) 771–790

    Abstract: High-entropy materials (HEMs) are new-fashioned functional materials in the field of catalysis owing to their large designing space, tunable electronic structure, interesting "cocktail effect", and entropy stabilization effect. Many effective strategies ... ...

    Abstract High-entropy materials (HEMs) are new-fashioned functional materials in the field of catalysis owing to their large designing space, tunable electronic structure, interesting "cocktail effect", and entropy stabilization effect. Many effective strategies have been developed to design advanced catalysts for various important reactions. Herein, we firstly review effective strategies developed so far for optimizing HEM-based catalysts and the underlying mechanism revealed by both theoretical simulations and experimental aspects. In light of this overview, we subsequently present some perspectives about the development of HEM-based catalysts and provide some serviceable guidelines and/or inspiration for further studying multicomponent catalysts.
    Language English
    Publishing date 2023-01-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d2sc06403k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Development of Polymethine Dyes for NIR-II Fluorescence Imaging and Therapy.

    Chen, Xin / Li, Jieyan / Roy, Shubham / Ullah, Zia / Gu, Jingsi / Huang, Haiyan / Yu, Chen / Wang, Xuejin / Wang, Han / Zhang, Yinghe / Guo, Bing

    Advanced healthcare materials

    2024  , Page(s) e2304506

    Abstract: Fluorescence imaging in the second near-infrared window (NIR-II) is burgeoning because of its higher imaging fidelity in monitoring physiological and pathological processes than clinical visible/the second near-infrared window fluorescence imaging. ... ...

    Abstract Fluorescence imaging in the second near-infrared window (NIR-II) is burgeoning because of its higher imaging fidelity in monitoring physiological and pathological processes than clinical visible/the second near-infrared window fluorescence imaging. Notably, the imaging fidelity is heavily dependent on fluorescence agents. So far, indocyanine green, one of the polymethine dyes, with good biocompatibility and renal clearance is the only dye approved by the Food and Drug Administration, but it shows relatively low NIR-II brightness. Importantly, tremendous efforts are devoted to synthesizing polymethine dyes for imaging preclinically and clinically. They have shown feasibility in the customization of structure and properties to fulfill various needs in imaging and therapy. Herein, a timely update on NIR-II polymethine dyes, with a special focus on molecular design strategies for fluorescent, photoacoustic, and multimodal imaging, is offered. Furthermore, the progress of polymethine dyes in sensing pathological biomarkers and even reporting drug release is illustrated. Moreover, the NIR-II fluorescence imaging-guided therapies with polymethine dyes are summarized regarding chemo-, photothermal, photodynamic, and multimodal approaches. In addition, artificial intelligence is pointed out for its potential to expedite dye development. This comprehensive review will inspire interest among a wide audience and offer a handbook for people with an interest in NIR-II polymethine dyes.
    Language English
    Publishing date 2024-03-05
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2649576-4
    ISSN 2192-2659 ; 2192-2640
    ISSN (online) 2192-2659
    ISSN 2192-2640
    DOI 10.1002/adhm.202304506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Breaking barriers in cancer treatment: nanobiohybrids empowered by modified bacteria and vesicles.

    Ijaz, Muhammad / Khurshid, Mohsin / Gu, Jingsi / Hasan, Ikram / Roy, Shubham / Ullah, Zia / Liang, Simin / Cheng, Jing / Zhang, Yinghe / Mi, Chao / Guo, Bing

    Nanoscale

    2024  Volume 16, Issue 18, Page(s) 8759–8777

    Abstract: Cancer, the leading global cause of mortality, poses a formidable challenge for treatment. The effectiveness of cancer therapies, ranging from chemotherapy to immunotherapy, relies on the precise delivery of therapeutic agents to tumor tissues. ... ...

    Abstract Cancer, the leading global cause of mortality, poses a formidable challenge for treatment. The effectiveness of cancer therapies, ranging from chemotherapy to immunotherapy, relies on the precise delivery of therapeutic agents to tumor tissues. Nanobiohybrids, resulting from the fusion of bacteria with nanomaterials, constitute a promising delivery system. Nanobiohybrids offer several advantages, including the ability to target tumors, genetic engineering capabilities, programmed product creation, and the potential for multimodal treatment. Recent advances in targeted tumor treatments have leveraged bacteria-based nanobiohybrids. Here, we outline the progress in cancer treatment using nanobiohybrids. Our focus is particularly on various therapeutic approaches within the context of nanobiohybrid systems, where bacteria are integrated with nanomaterials to combat cancer. It has been demonstrated that bacteria-based nanobiohybrids present a robust and effective method for tumor theranostics.
    MeSH term(s) Neoplasms/therapy ; Humans ; Bacteria/metabolism ; Animals ; Drug Delivery Systems ; Theranostic Nanomedicine ; Immunotherapy ; Nanostructures/chemistry ; Nanostructures/therapeutic use
    Language English
    Publishing date 2024-05-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr06666e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dual step-scheme heterojunction with full-visible-light-harvesting towards synergistic persulfate activation for enhanced photodegradation.

    Li, Zhiyang / Ai, Wei / Zhang, Yinghe / Zhang, Jianqiao / Bacha, Aziz-Ur-Rahim / Liu, Wenjie / Zhong, Dan / Cai, Yixiao / Jin, Wenbiao / Yang, Lei

    Journal of colloid and interface science

    2023  Volume 640, Page(s) 456–471

    Abstract: The occurrence of micropollutants in aquatic media raises great concern because of their biological toxicity and persistence. Herein, visible-light-driven photocatalyst titanium dioxide/graphitic carbon nitride/triiron tetraoxide ( ... ...

    Abstract The occurrence of micropollutants in aquatic media raises great concern because of their biological toxicity and persistence. Herein, visible-light-driven photocatalyst titanium dioxide/graphitic carbon nitride/triiron tetraoxide (TiO
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2023.02.101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Robust Superhydrophobic Surface Based on Multiple Hybrid Coatings for Application in Corrosion Protection.

    Zhou, Yaya / Ma, Yibing / Sun, Youyi / Xiong, Zhiyuan / Qi, Chunhong / Zhang, Yinghe / Liu, Yaqing

    ACS applied materials & interfaces

    2019  Volume 11, Issue 6, Page(s) 6512–6526

    Abstract: A new class of superhydrophobic surface based on multiple hybrid coatings is proposed and prepared to improve mechanical and reproduction stability. It does not only show a large water contact angle (ca. 174.5°) but also a slight decrease (ca. 6.4%) of ... ...

    Abstract A new class of superhydrophobic surface based on multiple hybrid coatings is proposed and prepared to improve mechanical and reproduction stability. It does not only show a large water contact angle (ca. 174.5°) but also a slight decrease (ca. 6.4%) of water contact angle after 100 mechanical abrasion cycles. Furthermore, the water contact angle changes slightly (relative standard deviation, 0.14%) for the three superhydrophobic surfaces prepared with the same procedure. The application of superhydrophobic multiple hybrid coatings in corrosion protection is further investigated by the Tafel polarization curves and electrochemical impedance spectroscopy. The superhydrophobic multiple hybrid coatings showed lower corrosion current (1.4 × 10
    Language English
    Publishing date 2019-01-30
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.8b19663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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