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  1. AU="Zhang, Yueqian"
  2. AU=Lima Emerson Q
  3. AU="Neil K. Taunk, MD"
  4. AU="Letourneau-Guillon, Laurent"
  5. AU="Dziuba, Marina V"
  6. AU="Aleksander Zińczuk"
  7. AU="Rowe, Logan M."
  8. AU="Sharma N." AU="Sharma N."
  9. AU=Yuan Shu
  10. AU="Ye Liu"
  11. AU="Bezerra, Antônio Diego M"
  12. AU="HE Xiufeng"
  13. AU=Freeman Hugh J AU=Freeman Hugh J
  14. AU="Choi, John Kim"
  15. AU="Streng, Bianca M M"
  16. AU="Franklin, Renty B"
  17. AU="Tetri, Laura H"
  18. AU="Badve, Sunil V"
  19. AU=Zhang Yinan
  20. AU="Piquero, Nicole Leeper"
  21. AU="Russo, Giorgio Ivan" AU="Russo, Giorgio Ivan"
  22. AU=Pourdowlat Guitti
  23. AU="Frisenda, Riccardo"
  24. AU=Palmucci Stefano

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  1. Artikel: DUAL: deep unsupervised simultaneous simulation and denoising for cryo-electron tomography.

    Zeng, Xiangrui / Ding, Yizhe / Zhang, Yueqian / Uddin, Mostofa Rafid / Dabouei, Ali / Xu, Min

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Recent biotechnological developments in cryo-electron tomography allow direct visualization of native sub-cellular structures with unprecedented details and provide essential information on protein functions/dysfunctions. Denoising can enhance the ... ...

    Abstract Recent biotechnological developments in cryo-electron tomography allow direct visualization of native sub-cellular structures with unprecedented details and provide essential information on protein functions/dysfunctions. Denoising can enhance the visualization of protein structures and distributions. Automatic annotation via data simulation can ameliorate the time-consuming manual labeling of large-scale datasets. Here, we combine the two major cryo-ET tasks together in DUAL, by a specific cyclic generative adversarial network with novel noise disentanglement. This enables end-to-end unsupervised learning that requires no labeled data for training. The denoising branch outperforms existing works and substantially improves downstream particle picking accuracy on benchmark datasets. The simulation branch provides learning-based cryo-ET simulation for the first time and generates synthetic tomograms indistinguishable from experimental ones. Through comprehensive evaluations, we showcase the effectiveness of DUAL in detecting macromolecular complexes across a wide range of molecular weights in experimental datasets. The versatility of DUAL is expected to empower cryo-ET researchers by improving visual interpretability, enhancing structural detection accuracy, expediting annotation processes, facilitating cross-domain model adaptability, and compensating for missing wedge artifacts. Our work represents a significant advancement in the unsupervised mining of protein structures in cryo-ET, offering a multifaceted tool that facilitates cryo-ET research.
    Sprache Englisch
    Erscheinungsdatum 2024-03-06
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2024.03.02.583135
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Evaluation and empirical research on the operation effect of the risk precontrol management system of safety in coal mines based on OSWM-TOPSIS.

    Liu, Quanlong / Zhao, Pan / Zhang, Yueqian / Li, Xinchun

    Work (Reading, Mass.)

    2021  Band 70, Heft 3, Seite(n) 795–804

    Abstract: Background: Most studies have focused on the establishment and application of the risk precontrol management system for safety in coal mines and have seldom considered the evaluation of the system operation effect.: Objective: This study aimed to ... ...

    Abstract Background: Most studies have focused on the establishment and application of the risk precontrol management system for safety in coal mines and have seldom considered the evaluation of the system operation effect.
    Objective: This study aimed to evaluate the operation effect of risk precontrol management system of safety in coal mines and propose policy suggestions to improve the risk precontrol management level of safety.
    Methods: This study applied the Objective and Subjective Weighting Method (OSWM) combined with the Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS) to conduct evaluation and empirical research on the operation effect of the risk precontrol management system of safety in coal mines.
    Results: First, the evaluation index system is mainly composed of six first-level indicators and 30 subordinate secondary indicators. Second, the OSWM combined with TOPSIS is an effective method for operation effect evaluation, which yields accurate and undistorted evaluation results. Third, the calculation reference value of the operation effect in the Gengcun coal mine is 57.34, and its corresponding effect level is level III, which is basically effective. Moreover, the calculation reference values of production equipment management (P4) and inspection, audit and review (P6) are the lowest, while the calculation reference values of risk precontrol management (P1) and auxiliary management (P5) reach the critical value corresponding to effect level I, which indicates a good operation effect.
    Conclusions: Corresponding policy suggestions to improve the risk precontrol management level in the Gengcun coal mine are proposed based on the above evaluation results.
    Mesh-Begriff(e) Coal ; Coal Mining ; Empirical Research ; Humans ; Risk Management
    Chemische Substanzen Coal
    Sprache Englisch
    Erscheinungsdatum 2021-10-31
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 1394194-x
    ISSN 1875-9270 ; 1051-9815
    ISSN (online) 1875-9270
    ISSN 1051-9815
    DOI 10.3233/WOR-205039
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Creating the Chinese version of the transgender attitudes and beliefs scale.

    Wang, Zhanqiang / Liu, Yang / Dong, Hanwen / Zhang, Yueqian / Yang, Kebing / Yang, Qingyan / Di, Xiaolan / Niu, Yajuan

    BMC psychology

    2024  Band 12, Heft 1, Seite(n) 167

    Abstract: Background: Trans persons' physical and mental health is easily affected by the attitude of those around them. However, China currently lacks a valid psychometric instrument to investigate people's attitudes toward trans persons. Therefore, this study ... ...

    Abstract Background: Trans persons' physical and mental health is easily affected by the attitude of those around them. However, China currently lacks a valid psychometric instrument to investigate people's attitudes toward trans persons. Therefore, this study modifies the English version of the Transgender Attitudes and Beliefs Scale (TABS) to suit the Chinese context. It subsequently examines the reliability and validity of the Chinese version of the TABS.
    Methods: This study recruited 1164 university students, aged 18-25 years, from 7 regions of China. SPSS26.0 and AMOS24.0 were used for data statistical analysis. Critical ratio method and correlation coefficient method were used for item analysis. Exploratory factor analysis and confirmatory factor analysis were used to test the structural validity of the Chinese version of Transgender Beliefs and Attitudes Scale, and the internal consistency reliability of the scale was tested.
    Results: The TABS-C contains 26 items with 3 factors. The Cronbach's alpha was 0.957 for the total scale and 0.945, 0.888, and 0.885 for the 3 factors. The half-point reliability of the scale was 0.936, and the retest reliability was 0.877. The Pearson correlation coefficients for the 3 factors and the total scale score ranged from 0.768 to 0.946.
    Conclusion: The TABS-C has reliable psychometric properties and is suitable for usage among college students in the Chinese context.
    Mesh-Begriff(e) Adolescent ; Adult ; Humans ; Young Adult ; Attitude ; Psychometrics/methods ; Reproducibility of Results ; Surveys and Questionnaires ; Transgender Persons/psychology ; Language
    Sprache Englisch
    Erscheinungsdatum 2024-03-21
    Erscheinungsland England
    Dokumenttyp Journal Article ; Validation Study
    ZDB-ID 2705921-2
    ISSN 2050-7283 ; 2050-7283
    ISSN (online) 2050-7283
    ISSN 2050-7283
    DOI 10.1186/s40359-024-01655-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Cell wall remodeling promotes callus formation in poplar.

    Zhang, Geng / Liu, Peipei / Zhang, Guifang / Yao, Xiaomin / Wang, Xinwei / Zhang, Yueqian / Lin, Jinxing / Cui, Yaning / Li, Xiaojuan

    Molecular horticulture

    2024  Band 4, Heft 1, Seite(n) 16

    Sprache Englisch
    Erscheinungsdatum 2024-04-29
    Erscheinungsland England
    Dokumenttyp Letter
    ISSN 2730-9401
    ISSN (online) 2730-9401
    DOI 10.1186/s43897-024-00093-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Inferring the solution space of microscope objective lenses using deep learning.

    Côté, Geoffroi / Zhang, Yueqian / Menke, Christoph / Lalonde, Jean-François / Thibault, Simon

    Optics express

    2022  Band 30, Heft 5, Seite(n) 6531–6545

    Abstract: Lens design extrapolation (LDE) is a data-driven approach to optical design that aims to generate new optical systems inspired by reference designs. Here, we build on a deep learning-enabled LDE framework with the aim of generating a significant variety ... ...

    Abstract Lens design extrapolation (LDE) is a data-driven approach to optical design that aims to generate new optical systems inspired by reference designs. Here, we build on a deep learning-enabled LDE framework with the aim of generating a significant variety of microscope objective lenses (MOLs) that are similar in structure to the reference MOLs, but with varied sequences-defined as a particular arrangement of glass elements, air gaps, and aperture stop placement. We first formulate LDE as a one-to-many problem-specifically, generating varied lenses for any set of specifications and lens sequence. Next, by quantifying the structure of a MOL from the slopes of its marginal ray, we improve the training objective to capture the structures of the reference MOLs (e.g., Double-Gauss, Lister, retrofocus, etc.). From only 34 reference MOLs, we generate designs across 7432 lens sequences and show that the inferred designs accurately capture the structural diversity and performance of the dataset. Our contribution answers two current challenges of the LDE framework: incorporating a meaningful one-to-many mapping, and successfully extrapolating to lens sequences unseen in the dataset-a problem much harder than the one of extrapolating to new specifications.
    Sprache Englisch
    Erscheinungsdatum 2022-03-18
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.451327
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Research on Coal Mine Building Compliance Inspection System Based on Accident Causation and BIM in China.

    Li, Xinchun / Zhang, Xiaolin / Liu, Quanlong / Zhang, Yueqian / Gu, Xiao / Qiu, Zunxiang

    International journal of environmental research and public health

    2022  Band 19, Heft 24

    Abstract: Coal mine construction projects have high risks, and non-compliant designs generated in the design stage will have adverse effects on subsequent construction and production stages. Therefore, it is of great importance to conduct effective preconstruction ...

    Abstract Coal mine construction projects have high risks, and non-compliant designs generated in the design stage will have adverse effects on subsequent construction and production stages. Therefore, it is of great importance to conduct effective preconstruction compliance inspections on coal mine construction designs. To make the compliance check of coal mine building design more rapid and effective, and to reduce the risks arising from the design phase, this study built a compliance inspection system for coal mine building design from the causes of coal mine accidents, using the Word2Vec word similarity calculation method and BIM platform secondary development technology. The system was tested and was found to be able to detect a 92.82% non-compliant component rate where the correct inspection rate was 97.68%. In addition, the inspection time for a single component was only 0.23 s. The construction of the compliance inspection system based on accident causes has changed the extensive inspection mode in the traditional manual model inspection, and the inspection no longer depends on the experience of inspectors, thus improving the efficiency and accuracy of coal mine building model inspection. The inspection focuses on the building elements with high risks, which achieves the purpose of risk control in the design stage.
    Mesh-Begriff(e) Accidents, Occupational ; Coal Mining ; China ; Causality ; Coal
    Chemische Substanzen Coal
    Sprache Englisch
    Erscheinungsdatum 2022-12-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph192416466
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Changes in physical activity and all-cause mortality in the oldest old population: Findings from the Chinese Longitudinal Healthy Longevity Survey (CLHLS).

    Yin, Ruoyu / Wang, Yinsu / Li, Yaxi / Lynn, Henry S / Zhang, Yueqian / Jin, Xurui / Yan, Lijing L

    Preventive medicine

    2023  Band 175, Seite(n) 107721

    Abstract: Background: Insufficient or decreasing physical activity is common in older adults. Most studies on physical activity changes and mortality were conducted in adults younger than 80 years old in developed countries. We aimed to investigate the ... ...

    Abstract Background: Insufficient or decreasing physical activity is common in older adults. Most studies on physical activity changes and mortality were conducted in adults younger than 80 years old in developed countries. We aimed to investigate the relationship between changes in physical activity and longevity in the oldest old (80 years or older) population using the Chinese Longitudinal Healthy Longevity Survey.
    Methods: Participants aged 80 or older at baseline were categorized into four groups: 1) remaining physically inactive (n = 14,287), 2) remaining physically active (n = 5411), 3) shifting from being inactive to active (n = 1364), and 4) shifting from being active to inactive (n = 1401). We fitted accelerated failure time Weibull survival regression models, adjusting for baseline sociodemographics, lifestyle factors and disease status. We further examined whether the associations differed by subgroups.
    Results: A total of 15,707 participants died during follow-up (median duration of follow-up = 3.0 years). Compared with participants who remained physically inactive, those who remained active (fully adjusted event time ratio (ETR): 1.14, 95%CI: 1.11-1.17) or shifted from being inactive to active (fully adjusted ETR: 1.14, 95%CI: 1.08-1.20) had statistically significant longer survival time. No significant association was observed between remaining physically inactive and shifting from being active to inactive. Subgroup analyses showed consistent associations in nearly all strata.
    Conclusion: Maintaining frequent physical activity or shifting from being physically inactive to active was consistently associated with longer survival time in the oldest old population. Our findings provide evidence for encouraging older adults to regularly engage in physical activity to gain longevity benefits.
    Mesh-Begriff(e) Aged ; Aged, 80 and over ; Humans ; China/epidemiology ; East Asian People ; Exercise ; Life Style ; Longevity ; Longitudinal Studies ; Mortality
    Sprache Englisch
    Erscheinungsdatum 2023-10-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 184600-0
    ISSN 1096-0260 ; 0091-7435
    ISSN (online) 1096-0260
    ISSN 0091-7435
    DOI 10.1016/j.ypmed.2023.107721
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: General analysis and optimization strategy to suppress autofluorescence in microscope lenses.

    Lu, Xiang / Zhang, Yueqian / Gross, Herbert

    Applied optics

    2019  Band 58, Heft 27, Seite(n) 7404–7415

    Abstract: With the development of fluorescence microcopy, the autofluorescence effect of optical glass in microscope lenses has become an important source of stray light which decreases the contrast of the image. However, the autofluorescence effect of various ... ...

    Abstract With the development of fluorescence microcopy, the autofluorescence effect of optical glass in microscope lenses has become an important source of stray light which decreases the contrast of the image. However, the autofluorescence effect of various types of microscope lenses has not been thoroughly discussed and the dominant factors of this effect are not clear. Currently, the most commonly used analysis method of the autofluorescence effect is based on the volume scattering model and Monte Carlo raytracing, which is extremely time-consuming due to the large number of rays that need to be traced. In our previous work, we have presented an efficient phase-space-based simulation method, which significantly accelerates the simulation of the autofluorescence effect [Appl. Opt.58, 3589 (2019)APOPAI0003-693510.1364/AO.58.003589]. Here we apply this new method on different types of microscope lenses and perform a systematic analysis of the autofluorescence effect based on the simulation results. In order to obtain an overview of the autofluorescence effect of different types of microscope lenses, more than 100 microscope lenses with different numerical aperture (NA), magnification, working distance, and immersion medium are selected and the corresponding autofluorescence contribution from each element in the lenses is calculated. Following a systematic analysis of the simulation result, we find that the autofluorescence effect of a lens is dependent on the etendue and complexity of the system, while the most critical elements are usually found in the front and rear groups. After the origins of the autofluorescence contribution from these critical lens groups have been found, possibilities to reduce the autofluorescence intensity have been investigated. Finally, effective methods to reduce the autofluorescence effect are presented and compared. The major contribution of this work is a detailed analysis of the impact of different factors on the autofluorescence effect, based on which a guideline is provided for the optical designers as well as the users to design or to select an appropriate microscope lens with low autofluorescence intensity.
    Sprache Englisch
    Erscheinungsdatum 2019-11-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.58.007404
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Efficient simulation of autofluorescence effects in microscope lenses.

    Lu, Xiang / Rodenko, Olga / Zhang, Yueqian / Gross, Herbert

    Applied optics

    2019  Band 58, Heft 13, Seite(n) 3589–3596

    Abstract: The use of fluorescence in microscopy is a well-known technology. Due to autofluorescence in the materials of optical components, the contrast of the image is degraded. The calculation of autofluorescence is usually performed by brute-force methods such ... ...

    Abstract The use of fluorescence in microscopy is a well-known technology. Due to autofluorescence in the materials of optical components, the contrast of the image is degraded. The calculation of autofluorescence is usually performed by brute-force methods such as the Monte Carlo-based volume scattering. The efficiency of calculations in this case is extremely low, and a huge number of rays must be calculated. In stray light calculations, the concept of important sampling is used to reduce computational effort. The idea is to calculate only rays, which have the chance to reach the target surface. The fluorescence conversion can be considered to be a scatter process, and therefore a modification of this idea is used here. The reduction factor is calculated by comparing the size of the illuminated phase space domain with the corresponding acceptance domain in every z plane of the lenses. The boundaries of the domains are determined by tracing the limiting rays of the light cone of the source as well as the pixel area under consideration. The small overlap of both domains can be estimated by geometrical considerations. The correct photometric scaling and the discretization of the volumes must be performed. The errors resulting from necessary approximations can be corrected without greatly increasing computational effort. The run time is reduced by a factor of 10
    Sprache Englisch
    Erscheinungsdatum 2019-01-31
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.58.003589
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: 3rd-order spherochromatism surface contribution and its intrinsic and induced aberration parts.

    Berner, Andrea / Kasperkiewicz, Ewa / Zhang, Yueqian / Gross, Herbert

    Journal of the Optical Society of America. A, Optics, image science, and vision

    2018  Band 35, Heft 8, Seite(n) 1368–1378

    Abstract: An investigation of the chromatic effects in refracting optical systems naturally shows that all five Seidel aberrations vary in wavelength because they are all dependent on the refractive index. In general, the color variation of spherical aberration is ...

    Abstract An investigation of the chromatic effects in refracting optical systems naturally shows that all five Seidel aberrations vary in wavelength because they are all dependent on the refractive index. In general, the color variation of spherical aberration is denoted as spherochromatism. Besides the chromatic variation of 1st-order paraxial parameters, e.g., focal length and magnification, described by axial and lateral color, spherochromatism can also strongly affect the color correction of an optical system. However, to the best of our knowledge, the literature shows no exact analytical formula available, specifying this effect. Actually, a general 3rd-order description based on the chromatic variation of Seidel's surface contribution for spherical aberration has not yet been considered. Therefore, this paper deals with this mentioned analytical gap and provides a description of a 3rd-order surface contribution for spherochromatism. Based on this, the result is analyzed and discussed concerning the differentiating between intrinsic and induced aberration parts. In the case of spherochromatism, its 3rd-order contribution shows induced effects caused by prior summed-up primary color aberrations of the system.
    Sprache Englisch
    Erscheinungsdatum 2018-08-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 283633-6
    ISSN 1520-8532 ; 1084-7529 ; 0740-3232
    ISSN (online) 1520-8532
    ISSN 1084-7529 ; 0740-3232
    DOI 10.1364/JOSAA.35.001368
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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