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Article ; Online: Local Government’s Land Finance Dependence and Migrants’ Settlement Intentions: Evidence from China

Zhang, Yuzheng / He, Shirui

Land. 2023 July 07, v. 12, no. 7

2023

Abstract: In the context of China’s new urbanization construction, it is crucial to deal with the issue of migrants. While land finance, as an essential means of local government financing in China over the past three decades, has made important contributions to ... ...

Abstract	In the context of China’s new urbanization construction, it is crucial to deal with the issue of migrants. While land finance, as an essential means of local government financing in China over the past three decades, has made important contributions to China’s economic growth, the impact of land finance on the settlement intentions of migrants still needs to be studied. This study considered cross-sectional data containing 78,642 samples based on the 2017 China Migrants Dynamic Survey 2017 (CMDS) and China Land and Resources Statistical Yearbook. In addition, a binary choice model was constructed, and the impact of the degree of land finance on the settlement intentions of migrants for the prefecture-level cities in China was empirically analyzed. With the help of the mediating- and moderating-effect models, the impact of the degree of land finance on the settlement intentions of migrants was examined from the perspectives of housing pressure, social security, and housing property rights. The results show the following: (1) The higher the degree of land finance, the lower the settlement intentions of migrants. (2) Land finance’s effect on settlement intentions is stronger for urban domiciles, low-skilled laborers, in large cities, and eastern and southern cities in these samples. (3) The higher the degree of land finance, the greater the housing pressure on the migrants, further reducing the settlement intentions of these individuals. However, social security and homeownership can reduce the negative effect of land finance on the settlement intentions of migrants. This paper provides policy implications for the construction of new urbanization and the realization of modernization.
Keywords	finance ; home ownership ; issues and policy ; land ; local government ; models ; modernization ; surveys ; urbanization ; China
Language	English
Dates of publication	2023-0707
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2682955-1
ISSN	2073-445X
ISSN	2073-445X
DOI	10.3390/land12071359
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA as noninvasive diagnostic markers for gastric cancer.

Fu, Yingli / Jiang, Jing / Wu, Yanhua / Cao, Donghui / Jia, Zhifang / Zhang, Yangyu / Li, Dongming / Cui, Yingnan / Zhang, Yuzheng / Cao, Xueyuan

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

2024

Abstract: Background: 5-Hydroxymethylcytosine-enriched gene profiles and regions show tissue-specific and tumor specific. There is a potential value to explore cell-free DNA 5-hydroxymethylcytosine feature biomarkers for early gastric cancer detection.: Methods! ...

Abstract	Background: 5-Hydroxymethylcytosine-enriched gene profiles and regions show tissue-specific and tumor specific. There is a potential value to explore cell-free DNA 5-hydroxymethylcytosine feature biomarkers for early gastric cancer detection. Methods: A matched case‒control study design with 50 gastric cancer patients and 50 controls was performed to sequence the different 5-hydroxymethylcytosine modification features of cell free DNA. Significantly differential 5-hydroxymethylcytosine modification genes were identified to construct a gastric cancer diagnostic model. Data set from GEO was used as an external testing set to test the robustness of the diagnostic model. Results: Accounting for more than 90% of 5-hydroxymethylcytosine peaks were distributed in the gene body in both the gastric cancer and control groups. The diagnostic model was developed based on five different 5-hydroxymethylcytosine modification genes, FBXL7, PDE3A, TPO, SNTG2 and STXBP5. The model could effectively distinguish gastric cancer patients from controls in the training (AUC = 0.95, sensitivity = 88.6%, specificity = 94.3%), validation (AUC = 0.87, sensitivity = 73.3%, specificity = 93.3%) and testing (AUC = 0.90, sensitivity = 81.9%, specificity = 90.2%) sets. The risk scores of the controls from the model were significantly lower than those of gastric cancer patients in both our own data (P < 0.001) and GEO external testing data (P < 0.001), and no significant difference between different TNM stage patients (P = 0.09 and 0.66). Furthermore, there was no significant difference between the healthy control and benign gastric disease patients in the testing set from GEO (P = 0.10). Conclusions: The characteristics of 5-hydroxymethylcytosine in cell free DNA are specific to gastric cancer patients, and the diagnostic model constructed by five genes' 5-hydroxymethylcytosine features could effectively identify gastric cancer patients.
Language	English
Publishing date	2024-04-07
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1463526-4
ISSN	1436-3305 ; 1436-3291
ISSN (online)	1436-3305
ISSN	1436-3291
DOI	10.1007/s10120-024-01493-7
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Article: The crosstalk among the physical tumor microenvironment and the effects of glucose deprivation on tumors in the past decade.

Cui, Yingnan / Sun, Yuanlin / Li, Dongming / Zhang, Yuzheng / Zhang, Yangyu / Cao, Donghui / Cao, Xueyuan

Frontiers in cell and developmental biology

2023 Volume 11, Page(s) 1275543

Abstract: The occurrence and progression of tumors are inseparable from glucose metabolism. With the development of tumors, the volume increases gradually and the nutritional supply of tumors cannot be fully guaranteed. The tumor microenvironment changes and ... ...

Abstract	The occurrence and progression of tumors are inseparable from glucose metabolism. With the development of tumors, the volume increases gradually and the nutritional supply of tumors cannot be fully guaranteed. The tumor microenvironment changes and glucose deficiency becomes the common stress environment of tumors. Here, we discuss the mutual influences between glucose deprivation and other features of the tumor microenvironment, such as hypoxia, immune escape, low pH, and oxidative stress. In the face of a series of stress responses brought by glucose deficiency, different types of tumors have different coping mechanisms. We summarize the tumor studies on glucose deficiency in the last decade and review the genes and pathways that determine the fate of tumors under harsh conditions. It turns out that most of these genes help tumor cells survive in glucose-deprivation conditions. The development of related inhibitors may bring new opportunities for the treatment of tumors.
Language	English
Publishing date	2023-11-01
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2737824-X
ISSN	2296-634X
ISSN	2296-634X
DOI	10.3389/fcell.2023.1275543
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Article ; Online: Accuracy of chest radiography compared to ultrasound for positioning the umbilical venous catheter in neonates: A meta-analysis and systematic review.

Cao, Juan / Zhang, Yuzheng / Yin, Yanling / Liu, Yuxiu

The journal of vascular access

2021 Volume 24, Issue 5, Page(s) 1051–1060

Abstract: This study was aimed to investigate the accuracy of anteroposterior chest radiography for tip position verification for the umbilical venous catheters in neonates compared to ultrasound. A search in the PubMed, Embase, the Cochrane Library, and EBSCO was ...

Abstract	This study was aimed to investigate the accuracy of anteroposterior chest radiography for tip position verification for the umbilical venous catheters in neonates compared to ultrasound. A search in the PubMed, Embase, the Cochrane Library, and EBSCO was conducted to evaluate all the related articles on umbilical venous catheter (UVC), ultrasound AND neonates updated to August, 2020. Study selection, data extraction, and quality assessment were performed independently by two investigators. Random effects model was used to estimate the pooled sensitivity, specificity, and diagnostic odds ratio (DOR). The summary receiver operator characteristic (SROC) curve was constructed, and the area under the SROC curve (AUC) was calculated. Fourteen related studies were finally included for meta-analysis. The overall diagnostic sensitivity and speciﬁcity of X-ray on tip verification of UVC were 0.90 (95% CI 0.71-0.97) and 0.82 (95% CI 0.53-0.95), respectively. The pooled DOR was 3.69 (95% CI 1.64-5.71). The AUC was 0.93 (95% CI 0.90-0.95). The meta-regression analysis suggested that study sample size, study design, different US confirming method, and different gold standard in original design might be potential sources of heterogeneity. Our conclusion is that the commonly used anteroposterior X-ray is not reliable in identifying the exact anatomical location of UVC tip in neonates. Studies suggested ultrasound or echocardiography with saline contrast injection could be the gold standard for verification of catheter location and should be considered whenever possible, especially in premature patients. More studies are needed to expand the use of ultrasound or echocardiography in tip position confirming of UVCs.
MeSH term(s)	Infant, Newborn ; Humans ; Ultrasonography ; Radiography ; Echocardiography ; Catheters ; Vascular Access Devices
Language	English
Publishing date	2021-11-16
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	2252820-9
ISSN	1724-6032 ; 1129-7298
ISSN (online)	1724-6032
ISSN	1129-7298
DOI	10.1177/11297298211046755
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Article ; Online: Chitosan Reduces Damages of Strawberry Seedlings under High-Temperature and High-Light Stress

Fu, Erting / Zhang, Yuzheng / Li, Brenda W. L. / Wang, Xiaozhe / Zhang, Hanxiao / Xiao, Wei / Chen, Xiude / Li, Ling

Agronomy. 2023 Feb. 10, v. 13, no. 2

2023

Abstract: High-temperature and high-light are the main adversity stresses faced by strawberry seedlings and open-field cultivation in summer. Chitosan (CTS) is widely used in agriculture as a soil amendment, plant growth regulator, and promoter of cold resistance. ...

Abstract	High-temperature and high-light are the main adversity stresses faced by strawberry seedlings and open-field cultivation in summer. Chitosan (CTS) is widely used in agriculture as a soil amendment, plant growth regulator, and promoter of cold resistance. However, the effects of CTS on strawberry seedlings under the combined stress of high-temperature and high-light are unclear. This study aimed to determine the effect of CTS on strawberry seedlings under the combined stress of high-temperature and high-light. In this study, Xuelixiang strawberry was used as the experimental plant material. The leaves were sprayed with 100 mg/Kg CTS or deionized aqueous solution and placed under high-temperature and high-light (38 °C, 1800 μ mol·m⁻²·s⁻¹, respectively) for 8 h. In addition, a suitable temperature and light (23 °C, 400 μ mol·m⁻²·s⁻¹, respectively) was sprayed with deionized water as a control. The results showed that compared with non-CTS treatment, the chlorophyll (Chl) content in strawberry plants increased by 16.9% after CTS treatment; the net CO₂ exchange (Pn) increased by 74.9%; and the maximum photochemical efficiency increased by 20.1%. In addition, CTS treatment increased the content of antioxidants; increased osmotic adjustment substances; improved the activity of reduced glutathione with reduced ascorbic acid (AsA-GSH) circulating antioxidant enzymes; removed reactive oxygen species in plants in time; and reduced the damage of reactive oxygen species to photosynthetic organs and cell membranes, thereby reducing high-temperature and high-light injury to strawberry seedlings. This study shows that CTS can improve the negative effects of high-temperature and high-light stress on strawberry seedlings.
Keywords	agronomy ; aqueous solutions ; ascorbic acid ; carbon dioxide ; chitosan ; chlorophyll ; cold ; glutathione ; photochemistry ; photosynthesis ; plant growth substances ; reactive oxygen species ; soil amendments ; strawberries ; summer ; temperature
Language	English
Dates of publication	2023-0210
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2607043-1
ISSN	2073-4395
ISSN	2073-4395
DOI	10.3390/agronomy13020517
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Comparative efficacy of treatments for patients with knee osteoarthritis: a network meta-analysis.

Li, Bingtong / Zhang, Yuzheng / Bi, Liqi

European journal of medical research

2020 Volume 25, Issue 1, Page(s) 27

Abstract: Background: Knee osteoarthritis is a common cause of musculoskeletal pain and a leading cause of disability and healthcare economic burden. The optimum treatment for knee osteoarthritis is still inconclusive. A network meta-analysis is required to ... ...

Abstract	Background: Knee osteoarthritis is a common cause of musculoskeletal pain and a leading cause of disability and healthcare economic burden. The optimum treatment for knee osteoarthritis is still inconclusive. A network meta-analysis is required to assess the efficacy and safety of treatments and provide more scientific medical evidence. Methods: Relevant studies were searched through PubMed, Embase, and Cochrane Library electronic databases from the inception to October 2018. Continuous outcomes such as pain, stiffness, physical function and total scores were expressed as the mean differences with 95% credible interval. Surface under the cumulative ranking curve illustrated the rank probability of each therapy under different outcomes. Results: Nineteen studies were included in this study, with a total of 2395 patients. For knee pain, platelet-rich plasma (0.691) was ranked at the first place, followed by hyaluronic acid combined with platelet-rich plasma (0.670) and hyaluronic acid (0.402). In terms of stiffness, hyaluronic acid combined with platelet-rich plasma (0.743) enjoyed the highest value, platelet-rich plasma (0.603) was the next and hyaluronic acid (0.386) was the third. As for physical function, the rank was hyaluronic acid combined with platelet-rich plasma (0.772), platelet-rich plasma (0.608) and hyaluronic acid (0.343). For total scores, the order given by surface under the cumulative ranking was hyaluronic acid combined with platelet-rich plasma (0.765), platelet-rich plasma (0.624) and hyaluronic acid (0.37). Conclusions: Hyaluronic acid combined with platelet-rich plasma showed the best efficacy in improving stiffness, physical function, and total scores, while platelet-rich plasma appeared the best in terms of pain reduction.
MeSH term(s)	Adjuvants, Immunologic/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Humans ; Hyaluronic Acid/therapeutic use ; Osteoarthritis, Knee/therapy ; Platelet-Rich Plasma/cytology ; Treatment Outcome
Chemical Substances	Adjuvants, Immunologic ; Anti-Inflammatory Agents, Non-Steroidal ; Hyaluronic Acid (9004-61-9)
Language	English
Publishing date	2020-07-20
Publishing country	England
Document type	Comparative Study ; Journal Article ; Meta-Analysis
ZDB-ID	1329381-3
ISSN	2047-783X ; 0949-2321
ISSN (online)	2047-783X
ISSN	0949-2321
DOI	10.1186/s40001-020-00426-1
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Article: Postprandial changes of oxidative stress biomarkers in healthy individuals.

Huang, Fengyi / Shen, Xue / Zhang, Yuzheng / Vuong, Ann M / Yang, Shuman

Frontiers in nutrition

2022 Volume 9, Page(s) 1007304

Abstract: Food consumption induces oxidative stress in humans, but the changes in oxidative stress levels after a regular meal are still unclear. We conducted an experimental study on 20 healthy volunteers (10 males, 10 females), who matched in age (±2 years). ... ...

Abstract	Food consumption induces oxidative stress in humans, but the changes in oxidative stress levels after a regular meal are still unclear. We conducted an experimental study on 20 healthy volunteers (10 males, 10 females), who matched in age (±2 years). They were given a regular diet (total energy of 704 kcal, which contains 75 g of carbohydrates, 35 g of protein, and 29 g of lipids) at 11:30 a.m. after a fast of over 12 h. We collected 6-repeated measures of venous blood samples at 2-h intervals
Language	English
Publishing date	2022-09-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2022.1007304
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Article ; Online: Health Technology Assessment in China's Health Care Sector: Development and Applications.

Guo, Wudong / Wang, Peimeng / Zhang, Yuzheng / Li, Xue / Wang, Yaoling / Zhao, Kun / Ruiz, Francis / Li, Rui / Xiao, Feiyi / Gu, Xuefei / You, Mao / Fu, Qiang

Health systems and reform

2024 Volume 9, Issue 3, Page(s) 2327099

Abstract: China's health system is facing severe challenges from social transition and the double burden of population aging and non-communicable diseases. Addressing the tension between the public's increasing demand for health services and the limited ... ...

Abstract	China's health system is facing severe challenges from social transition and the double burden of population aging and non-communicable diseases. Addressing the tension between the public's increasing demand for health services and the limited availability of medical resources has become a critical issue for health care policymakers and medical insurance fund administrators. In promoting its medical insurance system reform, China is actively developing health technology assessment (HTA) with principles and applications adapted to the Chinese context. This study aims to analyze the evolution of HTA in China with a focus on context, actors, process, content, and challenges encountered through applying a modified verson of Walt and Gilson's policy triangle framework. Currently, HTA plays an indispensable part in the reform of China's health care and medical insurance system, especially in the formulation and adjustment of the National Reimbursement Drug List (NRDL). While HTA is increasingly used in China, there remain challenges, such as the slow development of HTA related disciplines, lack of an independent national HTA authority, and limited scope in the use of HTA. Despite the identified challenges, HTA has the potential to support a wide range of applications in China's health care sector, building on the progress achieved over the last three decades.
MeSH term(s)	China ; Technology Assessment, Biomedical/methods ; Humans ; Health Care Reform/methods ; Health Care Reform/trends ; Health Care Sector/trends ; Health Policy ; Insurance, Health/trends ; Insurance, Health/statistics & numerical data
Language	English
Publishing date	2024-05-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2820935-7
ISSN	2328-8620 ; 2328-8620
ISSN (online)	2328-8620
ISSN	2328-8620
DOI	10.1080/23288604.2024.2327099
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Article ; Online: Quantifying magnetic resonance imaging features to classify placenta accreta spectrum (PAS) in high-risk gravid patients.

Chu, Caiting / Liu, Ming / Zhang, Yuzheng / Yu, Lingwei / Wang, Dengbin / Gao, Chengjin / Li, Wenhua

Clinical imaging

2021 Volume 80, Page(s) 50–57

Abstract: Objective: This study aimed to quantify the magnetic resonance imaging (MRI) features of placenta accreta spectrum (PAS) and to use MRI-based scores to classify them in high-risk gravid patients.: Materials and methods: The clinical data and MRI ... ...

Abstract	Objective: This study aimed to quantify the magnetic resonance imaging (MRI) features of placenta accreta spectrum (PAS) and to use MRI-based scores to classify them in high-risk gravid patients. Materials and methods: The clinical data and MRI features of 65 high-risk gravid patients diagnosed with PAS were retrospectively reviewed. The MRI features of PAS were analysed and compared using the chi-squared test, and the odds ratios (ORs) for significant risk factors for classification of PAS were identified via a multivariate logistic regression model. A receiver-operating characteristic (ROC) curve was used to calculate cut-off values and their corresponding sensitivity, specificity, and accuracy in classifying PAS. Results: We identified 3 significant risk features for classification of PAS, including placental heterogeneity (OR = 13.604), abnormal vascularization at the placental-maternal interface (OR = 9.528), and focal myometrial interruption (OR = 118.779). The significant risk features for classification of PAS were scored according to their OR values, as 3 points (OR ≥ 20), 2 points (10 ≤ OR < 20), or 1 point (OR < 10). Based on the scores of the 3 risk features, a cut-off score of 4.5 points achieved optimal sensitivity (94.3%), specificity (90%), and accuracy (92.3%) for classifying PAS in high-risk gravid patients. Conclusion: Quantifying these MRI features including placental heterogeneity, abnormal vascularization at the placental-maternal interface, and focal myometrial interruption can make a classification of PAS in high-risk gravid patients.
MeSH term(s)	Female ; Humans ; Magnetic Resonance Imaging ; Myometrium ; Placenta ; Placenta Accreta/diagnostic imaging ; Pregnancy ; Retrospective Studies
Language	English
Publishing date	2021-04-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	1028123-x
ISSN	1873-4499 ; 0899-7071
ISSN (online)	1873-4499
ISSN	0899-7071
DOI	10.1016/j.clinimag.2021.04.025
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Zs.A 1469: Show issues

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Article ; Online: Positive H. pylori status predicts better prognosis of non-cardiac gastric cancer patients: results from cohort study and meta-analysis.

Jia, Zhifang / Zheng, Min / Jiang, Jing / Cao, Donghui / Wu, Yanhua / Zhang, Yuzheng / Fu, Yingli / Cao, Xueyuan

BMC cancer

2022 Volume 22, Issue 1, Page(s) 155

Abstract: Background: Previous researches have associated Helicobacter pylori (H. pylori) with a prognosis of gastric cancer (GC), however, without a concert conclusion. This study aimed to study this issue further by a prospective cohort study and a meta- ... ...

Abstract	Background: Previous researches have associated Helicobacter pylori (H. pylori) with a prognosis of gastric cancer (GC), however, without a concert conclusion. This study aimed to study this issue further by a prospective cohort study and a meta-analysis. Methods: Histologically diagnosed gastric cancer (GC) patients were recruited into the primary prospective cohort study between January 2009 to December 2013. All the patients were followed-up periodically to record information on post-surgery therapy and overall survival status. The pre-surgery status of H. pylori was measured by enzyme-linked immunosorbent assay. A meta-analysis was conducted after retrieving related researches in the databases of PubMed and Embase up to April 2020. Pooled hazard ratios (HRs) and 95% confidence intervals (CIs) were summarized to validate the relationship between H. pylori infection and the survival time of GC patients. I Results: A total of 743 GC patients with radical tumorectomy were included prospectively and 516 (69.4%) were positive on H. pylori. H. pylori-positive patients tended to survive longer than -negative ones (HR 0.92, 95%CI: 0.74-1.15), though the tendency was not statistically significant. Cohort studies on the prognosis of GC were retrieved comprehensively by assessing the full-text and 59 published studies, together with the result of our study, were included in the further meta-analysis. The summarized results related the positive status of H. pylori to better overall survival (HR 0.81, 95%CI: 0.72-0.90) and disease-free survival (HR 0.83, 95%CI: 0.67-0.99). Results from subgroup analyses indicated that the pooled magnitude of this association was relatively lower in studies not referring to H. pylori in title and abstract. Conclusions: In conclusion, gastric cancer patients with H. pylori have a better prognosis than patients of H. pylori negative. More stringent surveillance strategies may be necessary for patients with H. pylori negative at cancer diagnosis.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Disease-Free Survival ; Female ; Follow-Up Studies ; Helicobacter Infections/complications ; Helicobacter Infections/microbiology ; Helicobacter pylori ; Humans ; Male ; Middle Aged ; Prognosis ; Proportional Hazards Models ; Prospective Studies ; Risk Factors ; Stomach Neoplasms/microbiology ; Stomach Neoplasms/mortality ; Young Adult
Language	English
Publishing date	2022-02-08
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Review
ZDB-ID	2041352-X
ISSN	1471-2407 ; 1471-2407
ISSN (online)	1471-2407
ISSN	1471-2407
DOI	10.1186/s12885-022-09222-y
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