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  1. Article ; Online: Tunable femtosecond optical parametric oscillators resonating at 0.65-1.02 µm and 1.07-2.3 µm.

    Heng, Jiaxing / Zhang, Rui / Qin, Mengke / Zhang, Zhaowei

    Optics letters

    2023  Volume 48, Issue 8, Page(s) 2082–2085

    Abstract: We present a singly resonant femtosecond optical parametric oscillator (OPO) cavity architecture supporting ultra-broadband wavelength tuning and efficient outcoupling of the generated optical pulses. Experimentally, we demonstrate an OPO with its ... ...

    Abstract We present a singly resonant femtosecond optical parametric oscillator (OPO) cavity architecture supporting ultra-broadband wavelength tuning and efficient outcoupling of the generated optical pulses. Experimentally, we demonstrate an OPO with its oscillating wavelength tuned over 652-1017 nm and 1075-2289 nm, spanning nearly 1.8 octaves. This is, as far as we know, the widest resonant-wave tuning range obtained from a green-pumped OPO. We show that intracavity dispersion management is crucial for the stationary and single-band operation of such a broadband wavelength tuning system. This architecture is universal, and therefore can be extended to allow the oscillation and ultra-broadband tuning of OPOs at various spectral regions.
    Language English
    Publishing date 2023-03-13
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.488301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Plant-Based Meat Proteins: Processing, Nutrition Composition, and Future Prospects.

    Yu, Jialing / Wang, Liyuan / Zhang, Zhaowei

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 22

    Abstract: The growing need for plant-based meat alternatives promotes the rapid progress of the food industry. Processing methods employed in plant-based meat production are critical to preserving and enhancing their nutritional content and health benefits, ... ...

    Abstract The growing need for plant-based meat alternatives promotes the rapid progress of the food industry. Processing methods employed in plant-based meat production are critical to preserving and enhancing their nutritional content and health benefits, directly impacting consumer acceptance. Unlike animal-based food processing, the efficiency of protein extraction and processing methods plays a crucial role in preserving and enriching the nutritional content and properties. To better understand the factors and mechanisms affecting nutrient composition during plant-based meat processing and identify key processing steps and control points, this work describes methods for extracting proteins from plants and processing techniques for plant-based products. We investigate the role of nutrients and changes in the nutrients during plant protein product processing. This article discusses current challenges and prospects.
    Language English
    Publishing date 2023-11-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12224180
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  3. Article ; Online: The molecular mechanisms of acetaminophen-induced hepatotoxicity and its potential therapeutic targets.

    Luo, Guangwen / Huang, Lili / Zhang, Zhaowei

    Experimental biology and medicine (Maywood, N.J.)

    2023  Volume 248, Issue 5, Page(s) 412–424

    Abstract: Acetaminophen (APAP), a widely used antipyretic and analgesic drug in clinics, is relatively safe at therapeutic doses; however, APAP overdose may lead to fatal acute liver injury. Currently, ...

    Abstract Acetaminophen (APAP), a widely used antipyretic and analgesic drug in clinics, is relatively safe at therapeutic doses; however, APAP overdose may lead to fatal acute liver injury. Currently,
    MeSH term(s) Humans ; Acetaminophen/adverse effects ; Oxidative Stress ; Chemical and Drug Induced Liver Injury/drug therapy ; Acetylcysteine/therapeutic use
    Chemical Substances Acetaminophen (362O9ITL9D) ; Acetylcysteine (WYQ7N0BPYC)
    Language English
    Publishing date 2023-01-20
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 4015-0
    ISSN 1535-3699 ; 1525-1373 ; 0037-9727
    ISSN (online) 1535-3699 ; 1525-1373
    ISSN 0037-9727
    DOI 10.1177/15353702221147563
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  4. Article ; Online: Phase-mismatched optical parametric oscillators based on aperiodic quasi-phase-matched crystals.

    Yu, Songyin / Qin, Mengke / Zhang, Zhaowei

    Optics letters

    2023  Volume 48, Issue 21, Page(s) 5483–5486

    Abstract: We present that femtosecond optical parametric oscillators (OPOs) based on aperiodic quasi-phase-matched (AQPM) crystals can be configured to operate in the "phase-mismatched" region. The phase-mismatch-induced frequency chirp is mainly introduced by the ...

    Abstract We present that femtosecond optical parametric oscillators (OPOs) based on aperiodic quasi-phase-matched (AQPM) crystals can be configured to operate in the "phase-mismatched" region. The phase-mismatch-induced frequency chirp is mainly introduced by the subcrystal that first interacts with pump pulses. By optimizing the intracavity group velocity dispersion and by selecting the direction of crystals, OPOs based on AQPM crystals could support the generation of wavelength-tunable, transform-limited pulses in an all-normal-dispersion cavity. In a preliminary experiment, transform-limited optical pulses with a tuning range over 1520-1660 nm were obtained by simply altering the cavity length. This scheme represents a unique and concise scheme of producing widely tunable, chirp-free femtosecond optical pulses.
    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.501921
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Efficacy and safety of belimumab in lupus nephritis: A retrospective study.

    Zhang, Zhaowei / Chen, Jiayin / Du, Hongwei / Hua, Li

    International journal of clinical pharmacology and therapeutics

    2023  

    Abstract: Objective: This retrospective analysis was to examine the efficacy and safety of belimumab in lupus nephritis in China.: Materials and methods: 25 patients who were regularly followed up every 3 months in our hospital in China were included. All ... ...

    Abstract Objective: This retrospective analysis was to examine the efficacy and safety of belimumab in lupus nephritis in China.
    Materials and methods: 25 patients who were regularly followed up every 3 months in our hospital in China were included. All patients were diagnosed as having lupus nephritis and received belimumab to complement standard therapy. The primary outcomes 24-hour proteinuria, complement level, estimated glomerular filtration rate (eGFR), SELENA-SLEDAI scores, prednisone daily dose, and adverse reactions were recorded at 12, 24, 36, and 48 weeks.
    Results: The SELENA-SLEDAI scores and 24-hour urine protein of the 25 patients decreased visibly from baseline 15.96 ± 3.02, 1.52 ± 1.72 to 9.52 ± 2.66 (p < 0.01), 0.5 ± 0.2 (p < 0.05) at 48 weeks, the eGFR of the 25 patients increased from 76.45 ± 22.2 to 85.48 ± 19.26 (p < 0.01) at 48 weeks, complement levels also showed a trend to increase. One patient experienced renal flare at 48 weeks, and the level of the patient's 24-hour proteinuria had been > 0.7 g at 6 months; this may be a strong predictive factor for further renal response at 12 months. Belimumab added to the standard therapy also improved the hematologic complications caused by systemic lupus erythematosus in 2 patients with a lower glucocorticoid dose. There were no serious adverse events.
    Conclusion: Belimumab may be effective and safe in lupus nephritis even with regard to hematologic complications.
    Language English
    Publishing date 2023-01-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124384-6
    ISSN 0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
    ISSN 0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
    DOI 10.5414/CP204323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 467: Show issues Location:
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  6. Article: Correlation Between Thyroid-Related Hormones and Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients with Normal Thyroid Function: A Retrospective Study.

    Xiao, Mei / Luo, Guangwen / Zhang, Zhaowei / Liu, Yanfen / Gong, Rui / Ke, Jianghuan

    Diabetes, metabolic syndrome and obesity : targets and therapy

    2024  Volume 17, Page(s) 1481–1490

    Abstract: Purpose: To investigate the correlation between thyroid-related hormones and diabetic retinopathy (DR) in euthyroid patients with type 2 diabetes mellitus (T2DM).: Patients and methods: Patients with T2DM admitted to our hospital between January 2023 ...

    Abstract Purpose: To investigate the correlation between thyroid-related hormones and diabetic retinopathy (DR) in euthyroid patients with type 2 diabetes mellitus (T2DM).
    Patients and methods: Patients with T2DM admitted to our hospital between January 2023 and June 2023 were retrospectively analyzed. The patients were divided into DR and non-diabetic retinopathy (NDR) groups according to whether DR occurred. Thyroid function-related hormones (TSH, FT3, and FT4), blood glucose indices (FBG and HbA1c), and blood lipid indices (HDL-C, LDL-C, TC, and TG) of the two groups were analyzed by univariate and multivariate logistic regression to explore the risk factors for DR. Pearson correlation analysis and multiple stepwise regression analysis were used to investigate the correlation of TSH or FT3 with FBG, HbA1c, and TG in DR patients.
    Results: Of the 286 patients with T2DM included in this study, 101 (35.31%) developed DR and 185 (64.69%) did not. High TG, FBG, HbA1c, and TSH and low FT3 levels were independent risk factors for DR in T2DM patients. TSH positively correlated with TG, whereas FT3 negatively correlated with TG and HbA1c in T2DM patients with DR.
    Conclusion: Higher TSH and lower FT3 in T2DM patients with normal thyroid function may affect glucose and lipid metabolism, thereby increasing the risk of DR.
    Language English
    Publishing date 2024-03-26
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494854-8
    ISSN 1178-7007
    ISSN 1178-7007
    DOI 10.2147/DMSO.S455428
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Dual-Tuning Azole-Based Ionic Liquids for Reversible CO

    Wang, Kaili / Zhang, Zhaowei / Wang, Shenyao / Jiang, Lili / Li, Haoran / Wang, Congmin

    ChemSusChem

    2024  , Page(s) e202301951

    Abstract: A strategy of tuning azole-based ionic liquids for reversible ... ...

    Abstract A strategy of tuning azole-based ionic liquids for reversible CO
    Language English
    Publishing date 2024-03-18
    Publishing country Germany
    Document type Journal Article
    ISSN 1864-564X
    ISSN (online) 1864-564X
    DOI 10.1002/cssc.202301951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Ecological and health risk assessments of heavy metals and their accumulation in a peanut-soil system.

    Zhang, Xiaoqing / Liu, Huanhuan / Li, Xin / Zhang, Zhaowei / Chen, Zhihua / Ren, Dajun / Zhang, Shuqin

    Environmental research

    2024  Volume 252, Issue Pt 2, Page(s) 118946

    Abstract: Heavy metals pollution is a notable threat to environment and human health. This study evaluated the potential ecological and health risks of heavy metals (Cu, Cr, Cd, Pb, Zn, Ni, and As) and their accumulation in a peanut-soil system based on 34 soil ... ...

    Abstract Heavy metals pollution is a notable threat to environment and human health. This study evaluated the potential ecological and health risks of heavy metals (Cu, Cr, Cd, Pb, Zn, Ni, and As) and their accumulation in a peanut-soil system based on 34 soil and peanut kernel paired samples across China. Soil As and Cd posed the greatest pollution risk with 47.1% and 17.6% of soil samples exceeding the risk screen levels, respectively, with 26.5% and 20.6% of the soil sites at relatively strong potential ecological risk level, respectively, and with the geo-accumulation levels at several soil sites in the uncontaminated to moderately contaminated categories. About 35.29% and 2.94% of soil sites were moderately and severely polluted based on Nemerow comprehensive pollution index, respectively, and a total of 32.4% of samples were at moderate ecological hazard level based on comprehensive potential ecological risk index values. The Cd, Cr, Ni, and Cu contents exceeded the standard in 11.76, 8.82, 11.76 and 5.88% of the peanut kernel samples, respectively. Soil metals posed more health risks to children than adults in the order As > Ni > Cr > Cu > Pb > Zn > Cd for non-carcinogenic health risks and Ni > Cr ≫ Cd > As > Pb for carcinogenic health risks. The soil As non-cancer risk index for children was greater than the permitted limits at 14 sites, and soil Ni and Cr posed the greatest carcinogenic risk to adults and children at many soil sites. The metals in peanut did not pose a non-carcinogenic risk according to standard. Peanut kernels had strong enrichment ability for Cd with an average bio-concentration factor (BCF) of 1.62. Soil metals contents and significant soil properties accounted for 35-74% of the variation in the BCF values of metals based on empirical prediction models.
    Language English
    Publishing date 2024-04-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2024.118946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
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  9. Article ; Online: Multi-soliton formation in femtosecond degenerate optical parametric oscillators.

    Ning, Chengxiao / Zhang, Zhaowei

    Optics letters

    2020  Volume 45, Issue 3, Page(s) 734–737

    Abstract: Multi-soliton formation is observed theoretically and experimentally in femtosecond degenerate optical parametric oscillators (OPOs). We show that when the pulse energy of the pump source of a femtosecond OPO is increased to a certain level, the existing ...

    Abstract Multi-soliton formation is observed theoretically and experimentally in femtosecond degenerate optical parametric oscillators (OPOs). We show that when the pulse energy of the pump source of a femtosecond OPO is increased to a certain level, the existing soliton will move towards the leading edge of pump pulses due to the enhanced nonlinear acceleration, and the undepleted pump energy will support the generation of more solitons. We have successfully observed the generation of double solitons and triple solitons in experimental demonstrations with the measured pulse characteristics agreeing well with the theoretical ones. The generation of multi-soliton sources may stimulate many novel applications, including data storage, telecommunication, and all-optical signal processing.
    Language English
    Publishing date 2020-02-06
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.383974
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Smartphone-Based Quantitative Detection of Ochratoxin A in Wheat via a Lateral Flow Assay

    Tian, Yunxin / Hu, Xiaofeng / Jiang, Jun / Tang, Xiaoqian / Tian, Zhiquan / Zhang, Zhaowei / Li, Peiwu

    Foods. 2023 Jan. 17, v. 12, no. 3

    2023  

    Abstract: Ochratoxin A (OTA) poses a severe health risk to livestock along the food chain. Moreover, according to the International Agency for Research on Cancer, it is also categorized as being possibly carcinogenic to humans. The lack of intelligent point-of- ... ...

    Abstract Ochratoxin A (OTA) poses a severe health risk to livestock along the food chain. Moreover, according to the International Agency for Research on Cancer, it is also categorized as being possibly carcinogenic to humans. The lack of intelligent point-of-care test (POCT) methods restricts its early detection and prevention. This work establishes a smartphone-enabled point-of-care test for OTA detection via a fluorescent lateral flow assay within 6 min. By using a smartphone and portable reader, the assay allows for the recording and sharing of the detection results in a cloud database. This intelligent POCT provided (iPOCT) a linearity range of 0.1–3.0 ng/mL and a limit of detection (LOD) of 0.02 ng/mL (0.32 µg/kg in wheat). By spiking OTA in blank wheat samples, the recoveries were 89.1–120.4%, with a relative standard deviation (RSD) between 3.9–9.1%. The repeatability and reproducibility were 94.2–101.7% and 94.6–103.4%, respectively. This work provides a promising intelligent POCT method for food safety.
    Keywords carcinogenicity ; databases ; detection limit ; fluorescence ; food chain ; food safety ; livestock ; mobile telephones ; ochratoxin A ; point-of-care systems ; risk ; standard deviation ; wheat
    Language English
    Dates of publication 2023-0117
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12030431
    Database NAL-Catalogue (AGRICOLA)

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