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  1. AU="Zhang, Zhiqun"
  2. AU="Jakobsen, Ingrid"
  3. AU="Ren, Aolin"
  4. AU="Chegni, Hamid"
  5. AU=Singer Eugenia
  6. AU=Narayan P
  7. AU="Daniele Coraci" AU="Daniele Coraci"
  8. AU=Ahn Anthony K
  9. AU="Pétrequin, Pierre"
  10. AU=Smit Cornelis AU=Smit Cornelis
  11. AU="Goyal, Sheenam"
  12. AU="Trullàs, Joan Carles"
  13. AU=Bedrood Sahar
  14. AU="Dharmaraj, Santhosh Kumar"

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  1. Artikel: Probing the carbon emissions in 30 regions of China based on symbolic regression and Tapio decoupling

    Zhang, Zhiqun

    Environmental science and pollution research. 2022 Jan., v. 29, no. 2

    2022  

    Abstract: Against the background of energy shortages and severe air pollution, countries around the world are aware of the importance of energy conservation and emission reduction; China is actively achieving emission reduction targets. In this study, we use a ... ...

    Abstract Against the background of energy shortages and severe air pollution, countries around the world are aware of the importance of energy conservation and emission reduction; China is actively achieving emission reduction targets. In this study, we use a symbolic regression to classify China’s regions according to the degree of influencing factors and calculate and analyze the inherent decoupling relationship between carbon emissions and economic growth in each region. Based on our results, we divided the 30 regions of the country into six categories according to the main influencing factors: GDP (13 regions), energy intensity (EI; 7 regions), industrial structure (IS; 3 regions), urbanization rate (UR; 3 regions), car ownership (CO; 2 regions), and household consumption level (HCL; 2 regions). Then, according to the order of the average carbon emissions in each region from high to low, these regions were further categorized as Type-EI, Type-UR, Type-GDP, Type-IS, Type-CO, or Type-HCL regions. The decoupling coefficient of the Type-UR region was the smallest with an expansive coupling and weak decoupling, whereas the other regions showed expansive negative decoupling, expansive coupling, and weak decoupling. Among them, the reduction rate of the decoupling coefficient in the Type-EI region was the largest at 6.65%. EI and GDP regions were the most notable contributors to emissions, based on which we provide policy recommendations.
    Schlagwörter air pollution ; carbon ; energy ; energy conservation ; household consumption ; issues and policy ; ownership ; research ; urbanization ; China
    Sprache Englisch
    Erscheinungsverlauf 2022-01
    Umfang p. 2650-2663.
    Erscheinungsort Springer Berlin Heidelberg
    Dokumenttyp Artikel
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-15648-x
    Datenquelle NAL Katalog (AGRICOLA)

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  2. Buch: Biomarkers of brain injury and neurological disorders

    Wang, Kevin K. W. / Zhang, Zhiqun / Kobeissy, Firas H.

    2015  

    Verfasserangabe ed. Kevin K. W. Wang ; Zhiqun Zhang ; Firas H. Kobeissy
    Schlagwörter Brain Injuries ; Biological Markers ; Nervous System Diseases
    Sprache Englisch
    Umfang XVII, 632 S. : Ill., graph. Darst.
    Verlag CRC Press
    Erscheinungsort Boca Raton u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    Anmerkung Includes bibliographical references and index
    HBZ-ID HT018419092
    ISBN 978-1-4822-3982-9 ; 1-4822-3982-5
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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    SignaturLeihstatusStandort
    2015 A 13 ausleihbar (Lesesaal) Lesesaal EG

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  3. Artikel ; Online: Erratum to “Inhibition of miR-21 improves pulmonary vascular responses in bronchopulmonary dysplasia by targeting the DDAH1/ADMA/NO pathway”

    Zhong Ying / Zhang Zhiqun / Chen Xiaoqing

    Open Medicine, Vol 18, Iss

    2023  Band 1

    Schlagwörter Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag De Gruyter
    Dokumenttyp Artikel ; Online
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  4. Artikel: Neonatal hemorrhage stroke and severe coagulopathy in a late preterm infant after receiving umbilical cord milking: A case report.

    Lu, Yan / Zhang, Zhi-Qun

    World journal of clinical cases

    2022  Band 10, Heft 16, Seite(n) 5365–5372

    Abstract: Background: Umbilical cord milking (UCM) is an alternative placental transfusion method for delayed umbilical cord clamping in routine obstetric practice, allowing prompt resuscitation of an infant. Thus, UCM has been adopted at some tertiary neonatal ... ...

    Abstract Background: Umbilical cord milking (UCM) is an alternative placental transfusion method for delayed umbilical cord clamping in routine obstetric practice, allowing prompt resuscitation of an infant. Thus, UCM has been adopted at some tertiary neonatal centers for preterm infants to enhance placental-to-fetal transfusion. It is not suggested for babies less than 28 wk of gestational age because it is associated with severe brain hemorrhage. For late preterm or term infants who do not require resuscitation, cord management is recommended to increase iron levels and prevent the development of iron deficiency anemia, which is associated with impaired motor development, behavioral problems, and cognitive delays. Concerns remain about whether UCM increases the incidence of intraventricular hemorrhage. However, there are very few reports of late preterm infants presenting with neonatal hemorrhage stroke (NHS) and severe coagulopathy after receiving UCM. Here, we report a case of a late preterm infant born at 34 wk of gestation. She abruptly deteriorated, exhibiting signs and symptoms of NHS and severe coagulopathy after receiving UCM on the first day of life.
    Case summary: A female preterm infant born at 34 wk of gestation received UCM after birth. She was small for her gestational age and described as vigorous with Apgar scores of 9 and 10 at one minute and five minutes of life, respectively. After hospitalization in the neonatal intensive care unit, she showed hypoglycemia and metabolic acidosis. The baby was administered glucose and sodium bicarbonate infusions. Intramuscular vitamin K1 was also used to prevent vitamin K deficiency. The baby developed umbilical cord bleeding and gastric bleeding on day 1 of life; a physical examination showed bilateral conjunctival hemorrhage, and a blood test showed thrombocytopenia, prolonged prothrombin time, prolonged activated partial thromboplastin time, low fibrinogen, raised D-dimer levels and anemia. A subsequent cranial ultrasound and computed tomography scan showed a left parenchymal brain hemorrhage with extension into the ventricular and subarachnoid spaces. The patient was diagnosed with NHS in addition to disseminated intravascular coagulation (DIC). Fresh frozen plasma (FFP) and prothrombin complex concentrate were given for coagulopathy. Red blood cell and platelet transfusions were provided for thrombocytopenia and anemia. A bolus of midazolam, intravenous calcium and phenobarbital sodium were administered to control seizures. The baby's clinical condition improved on day 5 of life, and the baby was hospitalized for 46 d and recovered well without seizure recurrence. Our case report suggests that preterm infants who receive UCM should undergo careful clinical assessment for intracranial hemorrhage, NHS and severe coagulopathy that may develop under certain circumstances. Supportive management, such as intensive care, FFP and blood transfusion, is recommended when the development of massive NHS and associated DIC is suspected.
    Conclusion: Our case report suggests that for late preterm infants who are small for gestational age and who receive UCM for alternative placental transfusion, neonatal health care professionals should be cautious in assessing the development of NHS and severe coagulopathy. Neonatal health care professionals should also be more cautious in assessing the complications of late preterm infants after they receive UCM.
    Sprache Englisch
    Erscheinungsdatum 2022-06-08
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v10.i16.5365
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: The combined effects of overweight/obesity and dietary antioxidant quality score on hypertension in children and adolescents.

    Zhong, Ying / Zhang, Zhiqun / Hu, Youfang

    BMC pediatrics

    2023  Band 23, Heft 1, Seite(n) 584

    Abstract: Background: This study was to evaluate the combined effects of overweight/obesity and DAQS on the risk of hypertension in children and adolescents.: Methods: In this cross-sectional study, the data of 14,316 subjects were extracted from the National ... ...

    Abstract Background: This study was to evaluate the combined effects of overweight/obesity and DAQS on the risk of hypertension in children and adolescents.
    Methods: In this cross-sectional study, the data of 14,316 subjects were extracted from the National Health and Nutrition Examination Survey (NHANES). Multivariate logistic regression analysis was used to explore the associations of obesity and DAQS with the risk of hypertension. The combined effect of overweight/obesity and DAQS on the risk of hypertension was evaluated.
    Results: Body mass index (BMI)-for-age < 85
    Conclusion: Overweight/obesity and DAQS had combined effects on the risk of hypertension in children and adolescents, which implied that for children and adolescents with normal weight, to keep normal weight combined with high quality of diet might be recommended.
    Mesh-Begriff(e) Male ; Humans ; Child ; Adolescent ; Overweight/complications ; Nutrition Surveys ; Antioxidants ; Cross-Sectional Studies ; Obesity/complications ; Hypertension/etiology ; Hypertension/complications ; Body Mass Index ; Diet
    Chemische Substanzen Antioxidants
    Sprache Englisch
    Erscheinungsdatum 2023-11-21
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-023-04397-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Erratum to "Inhibition of miR-21 improves pulmonary vascular responses in bronchopulmonary dysplasia by targeting the DDAH1/ADMA/NO pathway".

    Zhong, Ying / Zhang, Zhiqun / Chen, Xiaoqing

    Open medicine (Warsaw, Poland)

    2023  Band 18, Heft 1, Seite(n) 20230679

    Abstract: This corrects the article DOI: 10.1515/med-2022-0584.]. ...

    Abstract [This corrects the article DOI: 10.1515/med-2022-0584.].
    Sprache Englisch
    Erscheinungsdatum 2023-03-13
    Erscheinungsland Poland
    Dokumenttyp Published Erratum
    ZDB-ID 2829380-0
    ISSN 2391-5463
    ISSN 2391-5463
    DOI 10.1515/med-2023-0679
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Analysis of the association between the acetabular morphology and femoral head in children aged 0-3 years with developmental hip dysplasia.

    Xu, Liukun / Wang, Bo / Wang, Li / Zhang, Zhiqun

    Frontiers in pediatrics

    2023  Band 11, Seite(n) 1310411

    Abstract: Background: Magnetic resonance imaging (MRI) has been advocated as a routine examination for preoperative and postoperative assessment of Developmental Dysplasia of the Hip (DDH). However, there is limited research regarding the correlation between ... ...

    Abstract Background: Magnetic resonance imaging (MRI) has been advocated as a routine examination for preoperative and postoperative assessment of Developmental Dysplasia of the Hip (DDH). However, there is limited research regarding the correlation between acetabulum and femoral head morphology using preoperative MRI measurements.
    Objective: To explore the correlation between acetabulum and femoral head morphology in children with DDH aged 0-3 years, using MRI measurements as indicators.
    Methods: A Retrospective Analysis of MRI Data from 172 Children Diagnosed with Developmental Dysplasia of the Hip (DDH) at Nanjing Medical University Affiliated Children's Hospital, spanning from January 2017 to January 2022. Measurements were taken to assess various parameters reflecting hip socket morphology as well as the development status of the femoral head and ossifying nucleus. The correlation between these factors was explored using Pearson correlation analysis and multiple-factor linear regression. Statistical analysis was conducted using SPSS 18.0 software.
    Results: Pearson correlation analysis revealed statistically significant associations between the length of the ossifying nucleus ratio and age(mo.), BAI, BCAD, CTAD, and CTAD. The height of the ossifying nucleus ratio displayed statistically significant correlations with age(mo.) and BTAD. The length of the femoral head ratio exhibited statistically significant correlations with CAI, BCEA, and BCAD. Furthermore, the height of the femoral head ratio demonstrated a statistically significant correlation with BCEA. After adjusting for age(mo.), BMI, BCEA, and CCEA, BPoAcet and CPoAcet was found to be correlated with the length of the ossifying nucleus ratio. Preoperatively, the CAI, BAxAcet, BPoAcet, CPoAcet, and BTAD were correlated with the height of ossifying nucleus ratio after correcting for age, BMI, BCEA, and CCEA.
    Conclusion: The measurement parameters of hip socket morphology on MRI are associated with femoral head development, making them potential predictive indicators for femoral head development in DDH patients. These findings offer valuable insights for clinical decisions regarding the timing and approach of surgery in patients with developmental hip dislocation.
    Sprache Englisch
    Erscheinungsdatum 2023-11-27
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1310411
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Inhibition of miR-21 improves pulmonary vascular responses in bronchopulmonary dysplasia by targeting the DDAH1/ADMA/NO pathway

    Zhong Ying / Zhang Zhiqun / Chen Xiaoqing

    Open Medicine, Vol 17, Iss 1, Pp 1949-

    2022  Band 1964

    Abstract: miR-21 has been confirmed to be overexpressed in neonatal rat lungs with hyperoxia-mediated bronchopulmonary dysplasia (BPD). The specific function of miR-21 in BPD is still unclear. We established the hyperoxia-induced BPD rat model in vivo and the ... ...

    Abstract miR-21 has been confirmed to be overexpressed in neonatal rat lungs with hyperoxia-mediated bronchopulmonary dysplasia (BPD). The specific function of miR-21 in BPD is still unclear. We established the hyperoxia-induced BPD rat model in vivo and the hyperoxia-induced pulmonary microvascular endothelial cells (PMVECs) model in vitro. Transwell assay was utilized to detect the migratory capability of PMVECs. Tube formation assay was utilized to measure angiogenesis ability. ELISA was utilized to test nitric oxide (NO) production and the intracellular and extracellular Asymmetric Dimethylarginine (ADMA) concentration. Furthermore, the interaction between miR-21 and dimethylarginine dimethylaminohydrolase 1 (DDAH1) was evaluated using luciferase reporter assay. We found that miR-21 expression in PMVECs was increased by hyperoxia stimulation. Inhibition of miR-21 improved the migratory and angiogenic activities of PMVECs and overexpression of miR-21 exerted the opposite effects. Furthermore, knockdown of miR-21 increased NO production and decreased intracellular and extracellular ADMA concentration in hyperoxia-treated PMVECs. Next we proved that miR-21 could bind to DDAH1 and negatively regulate its expression. Rescues assays showed that DDAH1 knockdown reversed the effects of miR-21 depletion on hyperoxia-mediated PMVEC functions, NO production, and ADMA concentration. Importantly, miR-21 downregulation restored alveolarization and vascular density in BPD rats. This study demonstrates that inhibition of miR-21 improves pulmonary vascular responses in BPD by targeting the DDAH1/ADMA/NO pathway.
    Schlagwörter bronchopulmonary dysplasia ; mir-21 ; ddah1 ; adma ; no ; Medicine ; R
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2022-12-01T00:00:00Z
    Verlag De Gruyter
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel: Food protein-induced enterocolitis syndrome presenting after necrotizing enterocolitis in a preterm neonate: a case report.

    Lu, Yan / Zhang, Zhi-Qun

    Translational pediatrics

    2021  Band 10, Heft 5, Seite(n) 1393–1398

    Abstract: When bloody stools occur in a very-low-birth-weight infant in the neonatal intensive care unit (NICU), necrotizing enterocolitis (NEC) is a prime consideration, though food protein-induced enterocolitis syndrome (FPIES) can be causative and is difficult ... ...

    Abstract When bloody stools occur in a very-low-birth-weight infant in the neonatal intensive care unit (NICU), necrotizing enterocolitis (NEC) is a prime consideration, though food protein-induced enterocolitis syndrome (FPIES) can be causative and is difficult to distinguish from NEC. Food allergy is an adverse reaction following exposure to food due to an abnormal immunologic response to food, and cow's milk allergy (CMA) is the most likely form of food allergy in infants. The clinical features and proper management of patients with FPIES are important to differentiate FPIES from NEC. However, there are very few study reports of preterm infants presenting with food allergy-induced enterocolitis after NEC. Here, we report a case of a very-low-birth-weight infant born at 28 weeks of gestational age who developed recurrent episodes of bloody stools when he was fed cow's milk or given breast milk fortified with milk after NEC recovery on day of life (DOL) 29, 46, and 54. A male preterm infant born at 28 weeks of gestational age presented with bloody stools on DOL 7. He was diagnosed with early-onset NEC with abdominal tenderness, sluggish bowel sounds, increased C-reactive protein (CRP) level and pneumatosis intestinalis (PI). After recovery from NEC on DOL 20, the infant developed three recurrent episodes of bloody stools after being fed cow's milk or breast milk fortified with dairy milk. He was suspected of having recurrent episodes of NEC, but the infant was fairly healthy and did not present abdominal tenderness or abnormal bowel sounds on physical examination. Consecutive blood tests revealed normal CRP levels and increasing eosinophil levels. Abdominal radiograph revealed mild thickening of the small bowel, with no evidence of PI. The infant was finally diagnosed with FPIES in addition to NEC. After the infant received hydrolyzed formula, the bloody stool symptoms were finally resolved. Our case suggests that infants with recurrent episodes of bloody stools with increasing systemic eosinophils count should be considered for the diagnosis of FPIES with cow's milk formula. Rapid improvement and non-progression of systemic symptoms and signs after removing exposure to milk protein may differentiate FPIES from NEC.
    Sprache Englisch
    Erscheinungsdatum 2021-06-18
    Erscheinungsland China
    Dokumenttyp Case Reports
    ZDB-ID 2901309-4
    ISSN 2224-4344 ; 2224-4344 ; 2224-4336
    ISSN (online) 2224-4344
    ISSN 2224-4344 ; 2224-4336
    DOI 10.21037/tp-21-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Probing the carbon emissions in 30 regions of China based on symbolic regression and Tapio decoupling.

    Liu, Haiying / Zhang, Zhiqun

    Environmental science and pollution research international

    2021  Band 29, Heft 2, Seite(n) 2650–2663

    Abstract: Against the background of energy shortages and severe air pollution, countries around the world are aware of the importance of energy conservation and emission reduction; China is actively achieving emission reduction targets. In this study, we use a ... ...

    Abstract Against the background of energy shortages and severe air pollution, countries around the world are aware of the importance of energy conservation and emission reduction; China is actively achieving emission reduction targets. In this study, we use a symbolic regression to classify China's regions according to the degree of influencing factors and calculate and analyze the inherent decoupling relationship between carbon emissions and economic growth in each region. Based on our results, we divided the 30 regions of the country into six categories according to the main influencing factors: GDP (13 regions), energy intensity (EI; 7 regions), industrial structure (IS; 3 regions), urbanization rate (UR; 3 regions), car ownership (CO; 2 regions), and household consumption level (HCL; 2 regions). Then, according to the order of the average carbon emissions in each region from high to low, these regions were further categorized as Type-EI, Type-UR, Type-GDP, Type-IS, Type-CO, or Type-HCL regions. The decoupling coefficient of the Type-UR region was the smallest with an expansive coupling and weak decoupling, whereas the other regions showed expansive negative decoupling, expansive coupling, and weak decoupling. Among them, the reduction rate of the decoupling coefficient in the Type-EI region was the largest at 6.65%. EI and GDP regions were the most notable contributors to emissions, based on which we provide policy recommendations.
    Mesh-Begriff(e) Carbon/analysis ; Carbon Dioxide/analysis ; China ; Economic Development ; Urbanization
    Chemische Substanzen Carbon Dioxide (142M471B3J) ; Carbon (7440-44-0)
    Sprache Englisch
    Erscheinungsdatum 2021-08-10
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-15648-x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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