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  1. Article: Anti‐obesity and hypolipidemic effect of water extract from Pleurotus citrinopileatus in C57BL/6J mice

    Zhao, Changhui

    Food Science & Nutrition, 7(4):1295-1301

    2019  

    Abstract: Obesity has become one of the most important health problems worldwide requiring urgent need for efficient control. Pleurotus citrinopileatus (P. citrinopileatus)—a type of edible mushroom with abundant bioactive molecules—is a promising source for ... ...

    Abstract Obesity has become one of the most important health problems worldwide requiring urgent need for efficient control. Pleurotus citrinopileatus (P. citrinopileatus)—a type of edible mushroom with abundant bioactive molecules—is a promising source for achieving this goal. In the present study, we evaluated the anti‐obesity and hypolipidemic effect of P. citrinopileatus water extract (PWE) using a series of biochemical assays in randomized high‐fat diet‐induced obese (DIO) C57BL/6J mice, which were gavaged daily with low or high levels of PWE (400 or 800 mg/kg of body weight, respectively) in addition to high‐fat diet for 12 weeks. Results showed that PWE significantly reduced the weight gain, fat accumulation, and food intake of DIO mice within 12 weeks. PWE also decreased the serum triglycerides, cholesterol and low‐density lipoprotein, aspartate transaminase, nonesterified fatty acid, and creatinine, but increased high‐density lipoprotein. Additionally, PWE improved the glucose tolerance of mice fed with high fat. From above, we conclude that PWE has great potential as functional foods for management of obesity and/or associated metabolic disorders.
    Keywords glucose tolerance ; lipid profile ; mushroom
    Language English
    Document type Article
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  2. Article: Stability and in vitro digestibility of beta‐carotene in nanoemulsions fabricated with different carrier oils

    Zhao, Changhui

    Food Science & Nutrition, 6(8):2537-2544

    2018  

    Abstract: Beta‐carotene, the main dietary source of provitamin A, is required for maintaining optimum human health. The bioaccessibility of beta‐carotene can be greatly improved when ingested with fat. Therefore, the aim of the current study was to select proper ... ...

    Abstract Beta‐carotene, the main dietary source of provitamin A, is required for maintaining optimum human health. The bioaccessibility of beta‐carotene can be greatly improved when ingested with fat. Therefore, the aim of the current study was to select proper oils (palm oil, coconut oil, fish oil, and corn oil) as a carrier to form stable nanoemulsion that can effectively enhance the bioaccessibility of beta‐carotene. The nanoemulsion was formulated with 90% (v/v) aqueous solution (2% whey protein isolate, WPI, w/v) and 10% (v/v) dispersed oil. The in vitro digestion experiment of nanoemulsions showed that the bioaccessibility of beta‐carotene was as followed in order: palm oil = corn oil > fish oil > coconut oil (p < 0.05). The particle size of the nanoemulsion (initial particle size = 168–185 nm) was below 200 nm during 42 days’ storage at 25°C. The retention rates of beta‐carotene in nanoemulsions were 69.36%, 63.81%, 49.58%, and 54.91% with palm oil, coconut oil, fish oil, and corn oil, respectively. However, the particle size of the nanoemulsion increased significantly in the accelerated experiment at 55°C (p < 0.05), in which the retention rates of beta‐carotene were 48.56%, 43.41%, 29.35%, and 33.60% with palm oil, coconut oil, fish oil, and corn oil, respectively. From above, we conclude that WPI‐stabilized beta‐carotene nanoemulsion with palm oil as the carrier is the most suitable system to increase bioaccessibility and stability of lipid‐soluble bioactive compounds such as beta‐carotene.
    Keywords digestion ; edible oil ; nanoemulsion ; whey protein
    Language English
    Document type Article
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  3. Article ; Online: Comparison of the Extended Perichondrium-Cartilage Butterfly Inlay Technique and Over-Underlay Technique for Repairing Subtotal Perforation: A 2-Year Follow-up Study.

    Zhao, Chaowei

    Ear, nose, & throat journal

    2024  , Page(s) 1455613231225614

    Abstract: Objective: To compare graft outcomes and postoperative complications between the extended perichondrium-cartilage butterfly inlay (PCBI) technique and the perichondrium-cartilage over-underlay (PCOU) technique for repairing subtotal perforations over a ... ...

    Abstract Objective: To compare graft outcomes and postoperative complications between the extended perichondrium-cartilage butterfly inlay (PCBI) technique and the perichondrium-cartilage over-underlay (PCOU) technique for repairing subtotal perforations over a 2-year follow-up period.
    Methods and materials: Patients with subtotal perforations were prospectively randomized to either the extended PCBI (n = 52) or PCOU (n = 51) group. Evaluation metrics included operation time, graft success rate, hearing gain, and complications at 24 months postoperatively.
    Results: The study included 103 patients with 103 ears. Follow-up loss occurred in 11 of 52 patients (21.2%) in the PCBI group and 13 of 51 patients (25.5%) in the PCOU group (
    Conclusion: The endoscopic extended PCBI technique is safe and effective for repairing subtotal perforation. It avoids raising a tympanomeatal flap and demonstrates high long-term graft success with minimal complications.
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613231225614
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  4. Article: Limitations in membrane protein structure determination by lipid nanodiscs.

    Zhao, Chen

    Trends in biochemical sciences

    2024  

    Abstract: Lipid nanodiscs are popular mimetics of biological membranes for determining membrane protein structures. However, a recent study revealed that the choice of nanodisc scaffold directly influenced the structure of an ion channel. This finding prompts us ... ...

    Abstract Lipid nanodiscs are popular mimetics of biological membranes for determining membrane protein structures. However, a recent study revealed that the choice of nanodisc scaffold directly influenced the structure of an ion channel. This finding prompts us to be cautious and calls for improved membrane mimetics for structure determination.
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 194216-5
    ISSN 1362-4326 ; 0968-0004 ; 0376-5067
    ISSN (online) 1362-4326
    ISSN 0968-0004 ; 0376-5067
    DOI 10.1016/j.tibs.2024.03.010
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  5. Article ; Online: Endoscopic Broad Palisade Cartilage Graft Without Raising a Tympanomeatal Flap in the Repair of Subtotal Perforation.

    Zhao, Chaowei

    Ear, nose, & throat journal

    2024  , Page(s) 1455613241249030

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613241249030
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  6. Article ; Online: Can industrial structure optimization and industrial structure transition both lead to carbon lock-in mitigation? The case of China.

    Zhao, Congyu

    Environmental science and pollution research international

    2024  Volume 31, Issue 15, Page(s) 23247–23261

    Abstract: The optimization and transition of the industrial structure help improve the quality of the economy, moving it toward low-carbon development. By using the Instrumental Variable Generalized Method of Moments model and a city-level dataset covering the ... ...

    Abstract The optimization and transition of the industrial structure help improve the quality of the economy, moving it toward low-carbon development. By using the Instrumental Variable Generalized Method of Moments model and a city-level dataset covering the period 2006-2019, this paper explores the carbon lock-in mitigation effects of industrial structure optimization and industrial structure transition, respectively. The heterogeneity and the synthetic industrial structure adjustment effect are detected, and the potential impact mechanism is also explored. Some findings have been generated. (1) Both industrial structure optimization and industrial structure transition realize carbon lock-in eradication. (2) Industrial structure optimization and transition are more effective in inhibiting carbon lock-in in cities with a higher level of economic background. (3) By generating an interaction term of industrial structure optimization and transition and examining the impact of the interaction term on carbon lock-in, this paper detects that industrial structure optimization and transition have a synthetic impact on carbon lock-in, showing a "1 + 1 > 2" effect. (4) Industrial structure optimization and transition both affect carbon lock-in by improving technological innovation level, which is the impact mechanism. Some policy implications, such as sectoral diversification and promoting research and development, are put forward for better industrial structure development and carbon unlocking.
    MeSH term(s) Industry ; China ; Industrial Development ; Carbon ; Cities ; Economic Development
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2024-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32609-2
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  7. Book ; Thesis: JMJD3 regulates autophagy in a demethylase-independent manner

    Zhao, Cong

    2017  

    Author's details von Cong Zhao
    Language English
    Size 109 Blätter, Illustrationen, Diagramme
    Publishing place Frankfurt am Main
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Frankfurt am Main, 2017
    HBZ-ID HT019596890
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2018 E 164 order for loan Magazin

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  8. Article ; Online: Perichondrium-Cartilage Inlay Butterfly Myringoplasty: An Office-Based Procedure for Closing Small- to Medium-Sized Tympanic Membrane Perforations.

    Zhao, Chaowei

    Ear, nose, & throat journal

    2023  , Page(s) 1455613231178113

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2023-05-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613231178113
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  9. Article ; Online: Multiple papules on the genitalia in two young men.

    Zhao, Chunxia

    Australian journal of general practice

    2023  Volume 52, Issue 1-2, Page(s) 63–64

    MeSH term(s) Male ; Humans ; Skin Neoplasms ; Genitalia
    Language English
    Publishing date 2023-02-16
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2924889-9
    ISSN 2208-7958 ; 2208-794X
    ISSN (online) 2208-7958
    ISSN 2208-794X
    DOI 10.31128/AJGP-05-22-6436
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  10. Article ; Online: Cell culture:

    Zhao, Chongbei

    Journal of histotechnology

    2023  Volume 46, Issue 1, Page(s) 1–4

    MeSH term(s) Cell Culture Techniques
    Language English
    Publishing date 2023-01-24
    Publishing country England
    Document type Editorial
    ZDB-ID 604634-4
    ISSN 2046-0236 ; 0147-8885
    ISSN (online) 2046-0236
    ISSN 0147-8885
    DOI 10.1080/01478885.2023.2170772
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