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Article ; Online: Hybride bactérien et tumoral - un vaccin personnalisé contre le cancer.

Martinez, Alexandre / Zhao, Guorong / Kuhnast, Adrien / Toussaint, Bertrand

2023 Volume 39, Issue 10, Page(s) 790–792

Title translation	Bacterial and tumoral hybrid, a personalized cancer vaccine.
MeSH term(s)	Humans ; Cancer Vaccines/therapeutic use ; Bacteria ; Neoplasms/prevention & control
Chemical Substances	Cancer Vaccines
Language	French
Publishing date	2023-11-09
Publishing country	France
Document type	News
ZDB-ID	632733-3
ISSN	1958-5381 ; 0767-0974
ISSN (online)	1958-5381
ISSN	0767-0974
DOI	10.1051/medsci/2023108
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Article ; Online: The Impact of the Use of Hierarchical Teaching on Test Scores of Students’ Technology

Zhao Guorong / Yang Meng

SHS Web of Conferences, Vol 14, p

2015 Volume 01016

Abstract: Test scores of students’ technology is the main basis for physical examination of college students’ physical, fitness evaluation based on test results. To change the view by the stratified teaching method consistent system of teaching mode, special ... ...

Abstract	Test scores of students’ technology is the main basis for physical examination of college students’ physical, fitness evaluation based on test results. To change the view by the stratified teaching method consistent system of teaching mode, special movement technical level of students is improved significantly.
Keywords	layered approach ; the technical test ; affect ; Social Sciences ; H
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genome-Wide Identification and Transcriptional Expression Profiles of

Wu, Xiao-Tong / Xiong, Zhu-Pei / Chen, Kun-Xiang / Zhao, Guo-Rong / Feng, Ke-Ru / Li, Xiu-Hua / Li, Xi-Ran / Tian, Zhao / Huo, Fu-Lin / Wang, Meng-Xing / Song, Weining

Genes

2022 Volume 13, Issue 5

Abstract: The gene family protein phosphatase 2C (PP2C) is related to developmental processes and stress responses in plants. Barley ( ...

Abstract	The gene family protein phosphatase 2C (PP2C) is related to developmental processes and stress responses in plants. Barley (
MeSH term(s)	Domestication ; Genes, Plant ; Genome, Plant ; Hordeum/enzymology ; Hordeum/genetics ; Multigene Family ; Phylogeny ; Protein Phosphatase 2C/genetics
Chemical Substances	Protein Phosphatase 2C (EC 3.1.3.16)
Language	English
Publishing date	2022-05-07
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes13050834
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Article ; Online: Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2

ZHAO Guo-Rong

Journal of Integrative Medicine (JIM), Vol 2, Iss 5, Pp 333-

2004 Volume 336

Abstract: Objective: To explore the nature of pathology of sluggishness of lung-defensive qi and to offer objective experimental indexes for weifen syndrome (defensive phase syndrome). Methods: According to the completely random design, the plasma levels of ... ...

Abstract	Objective: To explore the nature of pathology of sluggishness of lung-defensive qi and to offer objective experimental indexes for weifen syndrome (defensive phase syndrome). Methods: According to the completely random design, the plasma levels of vasoactive intestinal peptide (VIP) and thromboxane B2 (TXB2) of 19 patients with weifen syndrome and 13 patients with qifen syndrome (qi phase syndrome) were detected by radioimmunoassay. The plasma levels of VIP and TXB2 at different stages of weifen syndrome and qifen syndrome were observed. Results: The plasma levels of VIP in weifen syndrome and in the late stage of weifen syndrome increased greatly at different stages as compared to qifen syndrome and the blank group (P<0.01), while the plasma level of TXB2 of weifen syndrome was higher only at the late stage than the blank group and qifen syndrome (P<0.01). As for the levels of VIP and TXB2 in weifen syndrome with different internal organs infected, there was no significant difference (P>0.05). Conclusion: VIP may be an index reflecting the pathology of weifen syndrome, and it is one of the material foundations of sluggishness of lung-defensive qi, but it has nothing to do with the infected internal organs. The level of TXB2 increases only after the fever of patients with weifen syndrome subsided, so it can not be the basis for diagnosis of the early stage of weifen syndrome. It doesn't increase in qifen syndrome either, the mechanism remains to be further studied.
Keywords	weifen diseases ; vasoactive intestinal peptide ; thromboxane B2 ; Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	610
Language	English
Publishing date	2004-09-01T00:00:00Z
Publisher	Journal of Chinese Integrative Medicine Press
Document type	Article ; Online
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Article: SEM Analysis of the Interfacial Transition Zone between Cement-Glass Powder Paste and Aggregate of Mortar under Microwave Curing.

Kong, Yaning / Wang, Peiming / Liu, Shuhua / Zhao, Guorong / Peng, Yu

Materials (Basel, Switzerland)

2016 Volume 9, Issue 9

Abstract: In order to investigate the effects of microwave curing on the microstructure of the interfacial transition zone of mortar prepared with a composite binder containing glass powder and to explain the mechanism of microwave curing on the improvement of ... ...

Abstract	In order to investigate the effects of microwave curing on the microstructure of the interfacial transition zone of mortar prepared with a composite binder containing glass powder and to explain the mechanism of microwave curing on the improvement of compressive strength, in this study, the compressive strength of mortar under microwave curing was compared against mortar cured using (a) normal curing at 20 ± 1 °C with relative humidity (RH) > 90%; (b) steam curing at 40 °C for 10 h; and (c) steam curing at 80 °C for 4 h. The microstructure of the interfacial transition zone of mortar under the four curing regimes was analyzed by Scanning electron microscopy (SEM). The results showed that the improvement of the compressive strength of mortar under microwave curing can be attributed to the amelioration of the microstructure of the interfacial transition zone. The hydration degree of cement is accelerated by the thermal effect of microwave curing and Na⁺ partially dissolved from the fine glass powder to form more reticular calcium silicate hydrate, which connects the aggregate, calcium hydroxide, and non-hydrated cement and glass powder into a denser integral structure. In addition, a more stable triangular structure of calcium hydroxide contributes to the improvement of compressive strength.
Language	English
Publishing date	2016-08-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma9090733
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Article ; Online: Effects of Siniruangan Recipe on Proliferation, Apoptosis and Activation of Human Hepatic Stellate Cell Line LX-2.

Liu, Jinming / Zhao, Guorong / Ai, Bichen / He, Yirong / Mei, Ming / Zou, Junju / Xiao, Biyue / Yin, Zhouan

Pharmacology

2019 Volume 104, Issue 5-6, Page(s) 342–351

Abstract: Background: Experimental and clinical evidence suggests that liver fibrosis is potentially reversible. Hepatic stellate cells (HSCs) play a key role in the development of hepatic fibrosis. Previous clinical applications and researches showed that ... ...

Abstract	Background: Experimental and clinical evidence suggests that liver fibrosis is potentially reversible. Hepatic stellate cells (HSCs) play a key role in the development of hepatic fibrosis. Previous clinical applications and researches showed that Siniruangan recipe (SNRG) reversed liver fibrosis and even liver cirrhosis. This experimental study aimed to elucidate the effects of SNRG on the proliferation, apoptosis and activation of HSCs. Methods: The human HSCs line LX-2 was cultured with normal culture medium and multi-dose SNRG water decoction for 48 h. Cell Counting Kit-8 assay was used to detect the proliferation and cytotoxicity of LX-2 cells. Annexin V-FITC/PI double staining was performed to identify apoptotic cells. Immunofluorescence staining was used to determine the relative content of cleaved caspase-3, tissue inhibitor of metalloproteinase-1 (TIMP-1) and transforming growth factor-β1 (TGF-β1) in LX-2 cells. Western blot was used to detect the relative content of Bcl-2, Bax, α-smooth muscle actin, β-catenin and TIMP-1 protein expression in LX-2 cells. Results: The SNRG inhibited the proliferation of LX-2 and induced cell apoptosis through caspase-dependent and mitochondrial-dependent pathways. SNRG may inhibit the activation of LX-2 through the β-catenin pathway. The decrease in TIMP-1 and TGF-β1 protein induced by SNRG promoted the degradation of the extracellular matrix (ECM). Conclusions: SNRG induced LX-2 cell apoptosis, inhibited cell proliferation, decreased LX-2 cell activity and promoted the degradation of ECM in vitro, which may be important mechanisms for reversing liver fibrosis and liver cirrhosis.
MeSH term(s)	Apoptosis/drug effects ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Hepatic Stellate Cells/drug effects ; Hepatic Stellate Cells/metabolism ; Humans ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Tissue Inhibitor of Metalloproteinase-1/metabolism ; Transforming Growth Factor beta1/metabolism
Chemical Substances	TGFB1 protein, human ; TIMP1 protein, human ; Tissue Inhibitor of Metalloproteinase-1 ; Transforming Growth Factor beta1
Language	English
Publishing date	2019-08-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	206671-3
ISSN	1423-0313 ; 0031-7012
ISSN (online)	1423-0313
ISSN	0031-7012
DOI	10.1159/000500800
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Article ; Online: Biomechanics analysis of human walking with load carriage.

Yang, Xiuxia / Zhao, Guorong / Liu, Di / Zhou, Weiei / Zhao, Hewei

Technology and health care : official journal of the European Society for Engineering and Medicine

2015 Volume 23 Suppl 2, Page(s) S567–75

Abstract: Background: Comprehensive analysis of the inherent laws and the biomechanic principles of human walking with load carriage and building kinematics, and kinematics model of human walking with load carriage, are very meaningful for the development of ... ...

Abstract	Background: Comprehensive analysis of the inherent laws and the biomechanic principles of human walking with load carriage and building kinematics, and kinematics model of human walking with load carriage, are very meaningful for the development of devices and apparatus that are related to human walking with load carriage, such as a lower limb exoskeleton. Objective: The gait experiment of human walking with load carriage is designed and performed in this paper. Methods: The obtained video is marked and analyzed by using SIMI motion analytical software. The space motion coordinates at each body's mark point that is needed in the kinematics model of established human walking with load carriage is obtained. Based on inverse kinematics, a dynamic model of human walking with load carriage is established. The SPSS statistical analysis software is used for statistical processing for determining key gait parameters. Results: The influence of load and speed on the walking gait parameters is analyzed systematically. Conclusions: The method provides a theoretical basis for the design of an exoskeleton.
MeSH term(s)	Biomechanical Phenomena ; Computer Simulation ; Exoskeleton Device ; Humans ; Lower Extremity/physiology ; Videotape Recording ; Walking/physiology ; Weight-Bearing/physiology
Language	English
Publishing date	2015
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1159961-3
ISSN	1878-7401 ; 0928-7329
ISSN (online)	1878-7401
ISSN	0928-7329
DOI	10.3233/THC-150995
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Article: Effects of Siniruangan Recipe on Proliferation, Apoptosis and Activation of Human Hepatic Stellate Cell Line LX-2

Liu, Jinming / Zhao, Guorong / Ai, Bichen / He, Yirong / Mei, Ming / Zou, Junju / Xiao, Biyue / Yin, Zhouan

Pharmacology

2019 Volume 104, Issue 5-6, Page(s) 342–351

Institution	Post-Graduate School, Hunan University of Chinese Medicine, Changsha, China College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, China Department of Internal Medicine, Southern University of Science and Technology Hospital, Shenzhen, China
Abstract	Background: Experimental and clinical evidence suggests that liver fibrosis is potentially reversible. Hepatic stellate cells (HSCs) play a key role in the development of hepatic fibrosis. Previous clinical applications and researches showed that Siniruangan recipe (SNRG) reversed liver fibrosis and even liver cirrhosis. This experimental study aimed to elucidate the effects of SNRG on the proliferation, apoptosis and activation of HSCs. Methods: The human HSCs line LX-2 was cultured with normal culture medium and multi-dose SNRG water decoction for 48 h. Cell Counting Kit-8 assay was used to detect the proliferation and cytotoxicity of LX-2 cells. Annexin V-FITC/PI double staining was performed to identify apoptotic cells. Immunofluorescence staining was used to determine the relative content of cleaved caspase-3, tissue inhibitor of metalloproteinase-1 (TIMP-1) and transforming growth factor-β1 (TGF-β1) in LX-2 cells. Western blot was used to detect the relative content of Bcl-2, Bax, α-smooth muscle actin, β-catenin and TIMP-1 protein expression in LX-2 cells. Results: The SNRG inhibited the proliferation of LX-2 and induced cell apoptosis through caspase-dependent and mitochondrial-dependent pathways. SNRG may inhibit the activation of LX-2 through the β-catenin pathway. The decrease in TIMP-1 and TGF-β1 protein induced by SNRG promoted the degradation of the extracellular matrix (ECM). Conclusions: SNRG induced LX-2 cell apoptosis, inhibited cell proliferation, decreased LX-2 cell activity and promoted the degradation of ECM in vitro, which may be important mechanisms for reversing liver fibrosis and liver cirrhosis.
Keywords	Siniruangan recipe ; Hepatic stellate cell ; LX-2 ; Proliferation ; Apoptosis ; Extracellular matrix
Language	English
Publishing date	2019-08-07
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Research Article
ZDB-ID	206671-3
ISSN	1423-0313 ; 0031-7012
ISSN (online)	1423-0313
ISSN	0031-7012
DOI	10.1159/000500800
Database	Karger publisher's database

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Article ; Online: Modified L-shaped surgical approach to excision of the sublingual gland.

Zhao, Guo-Rong / Ji, Ping / Zhao, Hong-Wei / Li, Yong / Li, Ying / Liu, Ping / Zeng, Lin / Zhang, Fu-Gui

The British journal of oral & maxillofacial surgery

2015 Volume 53, Issue 8, Page(s) 725–729

Abstract: We present a series of 1131 patients who were treated between 1981 and 2013 using the modified L-shaped angular surgical approach to excision of the sublingual gland, and describe the risks and benefits compared with the conventional approach. A total of ...

Abstract	We present a series of 1131 patients who were treated between 1981 and 2013 using the modified L-shaped angular surgical approach to excision of the sublingual gland, and describe the risks and benefits compared with the conventional approach. A total of 365 patients were treated with the conventional approach, while the other 766 have been treated since 1991 using the modified approach. There were no serious complications or recurrences during or after the operation in the modified series. There were significant differences between the two approaches in terms of injuries to the submandibular duct (p=0.03), incidence of ranula on the opposite side (p=0.02), amount of intraoperative bleeding (p=0.000), and duration of operation (p=0.000). The modified L-shaped incision is both viable and safe, and simplifies excision of the sublingual gland while protecting the submandibular duct.
MeSH term(s)	Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Feasibility Studies ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Oral Surgical Procedures ; Postoperative Hemorrhage/etiology ; Ranula/etiology ; Sublingual Gland/surgery ; Surgical Wound ; Young Adult
Language	English
Publishing date	2015-10
Publishing country	Scotland
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605685-4
ISSN	1532-1940 ; 0266-4356
ISSN (online)	1532-1940
ISSN	0266-4356
DOI	10.1016/j.bjoms.2015.04.024
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Article: A randomized controlled clinical study on treatment of hand, foot and mouth disease in children with Reduning injection.

Xu, Hua-shan / Zhuo, Zhi-qiang / Chen, Bao-chuan / Jing, Jiao / Zhao, Guo-rong / Wu, Jun-feng / Xiao, Wei

Chinese medical journal

2013 Volume 126, Issue 13, Page(s) 2585–2586

MeSH term(s)	Adolescent ; Antipyretics/therapeutic use ; Child ; Child, Preschool ; Drugs, Chinese Herbal/therapeutic use ; Female ; Hand, Foot and Mouth Disease/drug therapy ; Humans ; Infant ; Injections ; Male
Chemical Substances	Antipyretics ; Drugs, Chinese Herbal
Language	English
Publishing date	2013-07
Publishing country	China
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	127089-8
ISSN	0366-6999 ; 1002-0187
ISSN	0366-6999 ; 1002-0187
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