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  1. Article: [Modified application of interface screw in femoral side during anterior cruciate ligament reconstruction].

    Wang, Geng-Shen / Niu, Cun-Liang / Zhao, Hai-Yan / Wang, Shi-Zhong

    Zhongguo gu shang = China journal of orthopaedics and traumatology

    2023  Volume 36, Issue 8, Page(s) 754–759

    Abstract: Objective: To compare clinical effects of the improved interface screw fixation of femoral end of anterior cruciate ligament with classic femoral lateral loop plate fixation.: Methods: A retrospective analysis of 65 patients who underwent ... ...

    Abstract Objective: To compare clinical effects of the improved interface screw fixation of femoral end of anterior cruciate ligament with classic femoral lateral loop plate fixation.
    Methods: A retrospective analysis of 65 patients who underwent arthroscopic anterior cruciate ligament reconstruction from January 2019 to September 2021 were performed. According to the different fixation methods of the femoral side, 35 patients were divided into loop plate fixation(loop plate group), including 27 males and 8 females, aged from 18 to 50 years old with an average of (35.00±7.60) years old;30 patients in interface screw fixation(interface screw group), including 20 males and 10 females, aged from 18 to 50 years old with an average of (32.00±8.50) years old. Hospital stay, hospital expenses, operation time, complications, C-reactive protein at 1, 3, 6 days after operation, and postoperative Lysholm score and International Knee Documentation Committee(IKDC) score at 18 months were compared between two groups.
    Results: All patients were successfully operated, and obtained follow-up from 18 to 36 months with an average of (25.16±4.50) months. Anterior drawer test and Lachman test of all patients turned to negative. There were no statistical differences in hospital stay, hospital expenses and complications between two groups(
    Conclusion: In the reconstruction of anterior cruciate ligament, the common interface screw on the femoral side is changed to the sheath interface screw, and intramedullary screw is changed to the compression and fixation of tendon from outside to inside of joint. Although the operation procedure is relatively complicated and operation time is slightly longer, it has advantages of no residual metal foreign body after operation, and clinical effect is no different from classical loop plate suspension fixation, which is still a good choice.
    MeSH term(s) Female ; Male ; Humans ; Adolescent ; Young Adult ; Adult ; Middle Aged ; C-Reactive Protein ; Retrospective Studies ; Femur ; Anterior Cruciate Ligament Reconstruction ; Bone Screws
    Chemical Substances C-Reactive Protein (9007-41-4)
    Language Chinese
    Publishing date 2023-08-21
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1003-0034
    ISSN 1003-0034
    DOI 10.12200/j.issn.1003-0034.2023.08.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Curcumin activates autophagy and attenuates high glucose-induced apoptosis in HUVECs through the ROS/NF-κB signaling pathway.

    Jin, Qi-Hui / Hu, Xu-Jun / Zhao, Hai-Yan

    Experimental and therapeutic medicine

    2022  Volume 24, Issue 3, Page(s) 596

    Abstract: Curcumin (CUR) is well known for its anti-inflammatory and antioxidant effects. However, the endothelial protective effect of CUR in diabetes and the underlying signaling pathway remains unclear. The goal of the current study was to provide evidence ... ...

    Abstract Curcumin (CUR) is well known for its anti-inflammatory and antioxidant effects. However, the endothelial protective effect of CUR in diabetes and the underlying signaling pathway remains unclear. The goal of the current study was to provide evidence regarding the protective mechanism of CUR against the high glucose (HG)-induced damage to human umbilical vein endothelial cells (HUVECs). HG-induced HUVECs injury model was used to evaluate the protective effect and the underlying mechanism of CUR against endothelial injury. The cell viability was determined by the MTT method. The cell reactive oxygen species (ROS) were determined by using flow cytometry. The protein expression levels of Bcl-2, Bax, LC3-II/I, Beclin-1, p62, cleaved caspase-3, IκBα and NF-κB were measured by the western blotting. Results showed that CUR significantly decreased the cell apoptosis, the ROS generation and the inflammatory cytokine NF-κB activity in the HG-induced HUVECs versus the control, P<0.05. In addition, CUR significantly increased the expressions of LC3-II/I, Beclin-1, IκBα and Bax/Bcl-2 in the HG-induced HUVECs versus the control, P<0.05. Furthermore, the addition of autophagy inhibitor 3-MA impaired the autophagy, exacerbated the apoptotic death and increased the ROS and NF-κB levels in HUVECs under the high glucose condition, P<0.05. In brief, autophagy served a protective role in the HG-induced apoptosis in HUVECs and CUR alleviated apoptosis by promoting autophagy and inhibiting the ROS/NF-κB signaling pathway.
    Language English
    Publishing date 2022-07-28
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2683844-8
    ISSN 1792-1015 ; 1792-0981
    ISSN (online) 1792-1015
    ISSN 1792-0981
    DOI 10.3892/etm.2022.11533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chiral separation of sesquineolignans from the stems and leaves of Neoshirakia japonica.

    Zhao, Hai-Yan / He, Shuang / Lan, Qian / Su, Bao-Jun / Wang, Heng-Shan / Liang, Dong

    Phytochemistry

    2023  Volume 211, Page(s) 113683

    Abstract: Twelve pairs of sesquineolignan enantiomers (1a/1b-6a/6b and 1c/1d-6c/6d), including twenty one undescribed and three known (2b, 3b, and 4b) sesquineolignans were isolated from an ethanol extract of the stems and leaves of Neoshirakia japonica ( ... ...

    Abstract Twelve pairs of sesquineolignan enantiomers (1a/1b-6a/6b and 1c/1d-6c/6d), including twenty one undescribed and three known (2b, 3b, and 4b) sesquineolignans were isolated from an ethanol extract of the stems and leaves of Neoshirakia japonica (Euphorbiaceae). The successful separation of twelve pairs of enantiomers with mirror image-like electronic circular dichroism (ECD) curves and opposite specific rotation values, as one of the most important steps in compound isolation, was carried out by chiral HPLC columns. The absolute configurations of all undescribed sesquineolignans were elucidated by comprehensive analysis of their experimental ECD spectra. The effects of all the isolates on antineuroinflammatory and radical scavenging activity were evaluated. Compared with the positive control minocycline (IC
    MeSH term(s) Plant Leaves ; Euphorbiaceae ; Microglia ; Molecular Structure
    Language English
    Publishing date 2023-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 208884-8
    ISSN 1873-3700 ; 0031-9422
    ISSN (online) 1873-3700
    ISSN 0031-9422
    DOI 10.1016/j.phytochem.2023.113683
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Complete mitochondrial genome of

    Leng, Meng / Liu, Qiong / Zhao, Hai-Yan / Yu, Xiao-Fei / Yang, Mao-Fa

    Mitochondrial DNA. Part B, Resources

    2023  Volume 8, Issue 2, Page(s) 260–263

    Abstract: ... Gortyna ... ...

    Abstract Gortyna guizhouensis
    Language English
    Publishing date 2023-02-13
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2023.2176183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The complete mitochondrial genome of

    Chen, Xiao-Han / Leng, Meng / Yao, Di-Hui / Zhao, Hai-Yan / Yang, Mao-Fa

    Mitochondrial DNA. Part B, Resources

    2023  Volume 8, Issue 2, Page(s) 285–287

    Abstract: Picromerus ... ...

    Abstract Picromerus lewisi
    Language English
    Publishing date 2023-02-20
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2023.2179352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Trimethylamine N-oxide promotes oxidative stress and lipid accumulation in macrophage foam cells via the Nrf2/ABCA1 pathway.

    Luo, ZhiSheng / Yu, XiaoChen / Wang, Chao / Zhao, HaiYan / Wang, Xinming / Guan, XiuRu

    Journal of physiology and biochemistry

    2023  Volume 80, Issue 1, Page(s) 67–79

    Abstract: Recently, trimethylamine N-oxide (TMAO) has been considered a risk factor for cardiovascular disease and has a proatherogenic effect. Many studies have found that TMAO is involved in plaque oxidative stress and lipid metabolism, but the specific ... ...

    Abstract Recently, trimethylamine N-oxide (TMAO) has been considered a risk factor for cardiovascular disease and has a proatherogenic effect. Many studies have found that TMAO is involved in plaque oxidative stress and lipid metabolism, but the specific mechanism is still unclear. In our study, meta-analysis and bioinformatic analysis were firstly conducted in the database, and found that the effect of high plasma TMAO levels on promoting atherosclerotic plaque may be related to the expression of key antioxidant genes nuclear factor erytheroid-derived-2-like 2 (NFE2L2/Nrf2) decreased. Next, we assessed the role of Nrf2-mediated signaling pathway in TMAO-treated foam cells. Our results showed that TMAO can inhibit the expression of Nrf2 and its downstream antioxidant response element such as heme oxygenase-1 (HO-1) and glutathione peroxidase4 (GPX4), resulting in increased production of reactive oxygen species and decreased activity of superoxide dismutase, promoting oxidative stress. And TMAO can also promote lipid accumulation in foam cells by inhibiting cholesterol efflux protein expression. In addition, upregulation of Nrf2 expression partially rescues TMAO-induced oxidative stress and reduces ATP-binding cassette A1 (ABCA1)-mediated lipid accumulation. Therefore, TMAO promotes oxidative stress and lipid accumulation in macrophage foam cells through the Nrf2/ABCA1 pathway, which may provide a potential mechanism for the proatherogenic effect of TMAO.
    MeSH term(s) Humans ; Atherosclerosis/metabolism ; ATP Binding Cassette Transporter 1/genetics ; Foam Cells ; Lipids/pharmacology ; Macrophages/metabolism ; Methylamines/metabolism ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Plaque, Atherosclerotic
    Chemical Substances ABCA1 protein, human ; ATP Binding Cassette Transporter 1 ; Lipids ; Methylamines ; NF-E2-Related Factor 2 ; trimethyloxamine (FLD0K1SJ1A)
    Language English
    Publishing date 2023-11-07
    Publishing country Spain
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 1325104-1
    ISSN 1877-8755 ; 0034-9402 ; 1138-7548
    ISSN (online) 1877-8755
    ISSN 0034-9402 ; 1138-7548
    DOI 10.1007/s13105-023-00984-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Development of a Mind Map-based Predictive Nursing Protocol and its Impact on the Clarity of Images in Patients Undergoing High-concentration Contrast Three-dimensional Computed Tomography Imaging of Liver Blood Vessels.

    Zhao, Hai-Yan / Wang, Yan / Li, Xing / Zhou, Ying / Jiao, Zeng-Xin / Bao, Jun-Xia / Yang, Na / Zhang, Li-Li

    Current medical imaging

    2024  Volume 20, Page(s) 1–7

    Abstract: Objective: To explore the development of a mind map-based predictive nursing protocol and assess its impact on the quality of images in patients undergoing high-concentration contrast three-dimensional computed tomography (CT) imaging of liver blood ... ...

    Abstract Objective: To explore the development of a mind map-based predictive nursing protocol and assess its impact on the quality of images in patients undergoing high-concentration contrast three-dimensional computed tomography (CT) imaging of liver blood vessels.
    Methods: A total of 600 patients who were admitted to Beijing You an Hospital were chosen for this prospective study and underwent high-concentration contrast three-dimensional CT imaging of liver blood vessels between April 2021 and December 2021. The patients were divided into two groups using the digital table method, with 300 cases. The control group received conventional nursing intervention, while the research group was provided with a mind map-based predictive nursing protocol. We recorded the image quality of three-dimensional CT imaging of liver blood vessels, satisfaction scores regarding nurse examination guidance, and the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) in both groups.
    Results: The research group achieved a perfect rate of 100.00% for the high-quality three-dimensional CT imaging of liver blood vessels, which was noticeably higher compared to the rate of the control group of 98.67%. Patients in the research group expressed higher satisfaction levels regarding the guidance provided by nurses, including their attitude, timeliness, accuracy, and overall satisfaction, compared to the control group. Initially, the two groups had no notable differences in the SAS and SDS scores. However, after the intervention, both groups experienced a significant decrease in SAS and SDS scores, with the research group showing an even more substantial decline.
    Conclusion: Through the creation of a mind map-based predictive nursing protocol and its implementation on patients undergoing high-concentration contrast three-dimensional CT imaging of liver blood vessels, it is possible to significantly enhance the quality of CT scans, alleviate feelings of anxiety and depression, increase patient satisfaction with examination guidance by nurses, and effectively decrease the occurrences of contrast agent leakage and allergic reactions to iodine.
    MeSH term(s) Humans ; Prospective Studies ; Contrast Media ; Tomography, X-Ray Computed/methods ; Iodine ; Liver/diagnostic imaging
    Chemical Substances Contrast Media ; Iodine (9679TC07X4)
    Language English
    Publishing date 2024-02-22
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/0115734056263792231112113912
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Glycosides with galloyl groups from

    Zhao, Hai-Yan / He, Shuang / Lan, Qian / Su, Bao-Jun / Wang, Heng-Shan / Liang, Dong

    Natural product research

    2023  Volume 38, Issue 6, Page(s) 947–955

    Abstract: Seven new glycosides ( ...

    Abstract Seven new glycosides (
    MeSH term(s) Glycosides/pharmacology ; Glycosides/chemistry ; Magnetic Resonance Spectroscopy ; Microglia ; Nitric Oxide ; Molecular Structure ; Sapium
    Chemical Substances Glycosides ; Nitric Oxide (31C4KY9ESH)
    Language English
    Publishing date 2023-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2208356
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  9. Article ; Online: Chiral separation of sesquineolignans from the stems and leaves of Neoshirakia japonica

    Zhao, Hai-Yan / He, Shuang / Lan, Qian / Su, Bao-Jun / Wang, Heng-Shan / Liang, Dong

    Phytochemistry. 2023 July, v. 211 p.113683-

    2023  

    Abstract: Twelve pairs of sesquineolignan enantiomers (1a/1b−6a/6b and 1c/1d−6c/6d), including twenty one undescribed and three known (2b, 3b, and 4b) sesquineolignans were isolated from an ethanol extract of the stems and leaves of Neoshirakia japonica ( ... ...

    Abstract Twelve pairs of sesquineolignan enantiomers (1a/1b−6a/6b and 1c/1d−6c/6d), including twenty one undescribed and three known (2b, 3b, and 4b) sesquineolignans were isolated from an ethanol extract of the stems and leaves of Neoshirakia japonica (Euphorbiaceae). The successful separation of twelve pairs of enantiomers with mirror image-like electronic circular dichroism (ECD) curves and opposite specific rotation values, as one of the most important steps in compound isolation, was carried out by chiral HPLC columns. The absolute configurations of all undescribed sesquineolignans were elucidated by comprehensive analysis of their experimental ECD spectra. The effects of all the isolates on antineuroinflammatory and radical scavenging activity were evaluated. Compared with the positive control minocycline (IC₅₀ = 1.2 μM), compounds 1a/1b/1c/1d−6a/6b/6c/6d with IC₅₀ values being greater than 50 μM displayed almost no effect on the inhibition of NO production in LPS-induced BV-2 microglial cells. The results of DPPH-radical scavenging activity for them showed that compound 3c had moderate radical scavenging ability (EC₅₀ = 48.47 μM), while the EC₅₀ value of positive control vitamin C was 18.21 μM.
    Keywords Euphorbiaceae ; ascorbic acid ; circular dichroism spectroscopy ; enantiomers ; ethanol ; minocycline ; plant biochemistry ; Neoshirakia japonica ; Sesquineolignans ; Chiral HPLC separation ; Antineuroinflammatory activity ; Radical scavenging activity
    Language English
    Dates of publication 2023-07
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 208884-8
    ISSN 1873-3700 ; 0031-9422
    ISSN (online) 1873-3700
    ISSN 0031-9422
    DOI 10.1016/j.phytochem.2023.113683
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Identification of peanut oil origins based on Raman spectroscopy combined with multivariate data analysis methods1

    ZHU, Peng-fei / YANG, Qing-li / ZHAO, Hai-yan

    CAAS. Publishing services by Elsevier B.V Journal of integrative agriculture. 2022,

    2022  

    Abstract: This study aimed to use Raman spectroscopy to identify the producing areas of peanut oil and build a robust discriminant model to further screen out the characteristic spectra closely related to the origin. Raman spectra of 159 peanut oil samples from ... ...

    Abstract This study aimed to use Raman spectroscopy to identify the producing areas of peanut oil and build a robust discriminant model to further screen out the characteristic spectra closely related to the origin. Raman spectra of 159 peanut oil samples from different provinces and different cities of the same province were collected. The obtained data were analyzed by stepwise linear discriminant analysis (SLDA), k-nearest neighbor analysis (k-NN) and multi-way analysis of variance. The results showed that the overall recognition rate of samples based on full spectra was higher than 90%. The producing origin, variety and their interaction influenced Raman spectra of peanut oil significantly, and 1400-1500 cm⁻¹ and 1600-1700 cm⁻¹ were selected as the characteristic spectra of origin and less affected by variety. The best classification model established by SLDA combined with characteristic spectra could rapidly and accurately identify peanut oil’s origin.
    Keywords Raman spectroscopy ; agriculture ; discriminant analysis ; models ; multivariate analysis ; peanut oil
    Language English
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ZDB-ID 2660426-7
    ISSN 2095-3119
    ISSN 2095-3119
    DOI 10.1016/j.jia.2022.07.026
    Database NAL-Catalogue (AGRICOLA)

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