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Article ; Online: An optimization scheme of partial total homomorphic encryption

Luo Guangqiao / Zhao Haijun / Chen Huayue

SHS Web of Conferences, Vol 166, p

2023 Volume 01025

Abstract: In order to further improve the effectiveness of homomorphic cryptography, we optimize Lauter et al. 's partial homomorphic cryptography scheme, and propose a new RLWE-based total homomorphic cryptography (FHE) scheme, which combines a series of existing ...

Abstract	In order to further improve the effectiveness of homomorphic cryptography, we optimize Lauter et al. 's partial homomorphic cryptography scheme, and propose a new RLWE-based total homomorphic cryptography (FHE) scheme, which combines a series of existing techniques with the Chinese residual theory, and merges several “plaintext slots” into a ciphertext for homomorphic computation. The extended key transformation technology and modulo transformation technology are used to reduce the noise of ciphertext and enable it to carry out the next homomorphic operation. Compared with the original scheme, the security and effectiveness of the scheme were studied on the premise of ensuring CPA security, and the results showed that the performance of the scheme was improved by N times.
Keywords	Social Sciences ; H
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Bypass Surgery Management of Complex Proximal and Distal Posterior Inferior Cerebellar Artery Aneurysms.

Zhao, Haijun / Tong, Xiaoguang

The Journal of craniofacial surgery

2022 Volume 33, Issue 7, Page(s) 2049–2054

Abstract: Background: For the complex posterior inferior cerebellar artery (PICA) aneurysms, standard microsurgical or endovascular technical options were not feasible. To determine the efficacy and outcomes of bypass surgery for complex PICA aneurysms, the ... ...

Abstract	Background: For the complex posterior inferior cerebellar artery (PICA) aneurysms, standard microsurgical or endovascular technical options were not feasible. To determine the efficacy and outcomes of bypass surgery for complex PICA aneurysms, the authors herein review our recent surgical experience for complex PICA aneurysms. Methods: The authors retrospectively reviewed our experience of extracranial-intracranial bypass and intracranial-intracranial bypass surgery in treatment of proximal and distal complex PICA aneurysms at our institution from 2016 to 2020. Results: Twelve patients harboring 12 complex PICA aneurysms received bypass surgery at our institution. Seven (58.3%) patients with proximal PICA aneurysms underwent extracranial-intracranial bypass. Five (41.7%) patients with distal PICA aneurysms accepted intracranial-intracranial bypass. The postoperative symptom improvement: Of the 6 patients with preoperative hypoperfusion or ischemic of the cerebellar hemisphere, the symptom resolved in 5 patients, improved in 1 patient, of 5 patients with preoperative mass effect, the symptom resolved in 5 patients. During the follow-up period, ten patients had a modified Rankin scale (mRS) score of 0 to 1, and 1 patient had an mRS score of 2. One patient had an mRS score of 3. The long-term graft patency rate was 91.7%. All patients had no recurrence of intracranial aneurysm. Conclusions: Base on the complexity of anatomy structure and the vascular architecture, an individualized strategy was proposed for each patient. The use of different types of bypass procedures (occipital artery-PICA end-to-end bypass, PICA-PICA end-to-end anastomosis, and/or occipital artery graft) can safely and effectively manage these complex PICA aneurysms.
MeSH term(s)	Cerebellum/diagnostic imaging ; Cerebellum/surgery ; Cerebral Revascularization/methods ; Humans ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Retrospective Studies ; Vertebral Artery/surgery
Language	English
Publishing date	2022-02-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000008507
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Article ; Online: Surgical Treatment Strategies for Residual or Recurrent Intracranial Aneurysms Following Endovascular Embolization.

Zhao, Haijun / Gao, Kaiming / Shi, Minggang / Shang, Yanguo / Tong, Xiaoguang

The Journal of craniofacial surgery

2024

Abstract: Objective: To explore how to effectively manage the residual or recurrent intracranial aneurysms after embolization.: Methods: The authors retrospectively reviewed our experience of endovascular interventional therapy, surgical clipping, and ... ...

Abstract	Objective: To explore how to effectively manage the residual or recurrent intracranial aneurysms after embolization. Methods: The authors retrospectively reviewed our experience of endovascular interventional therapy, surgical clipping, and cerebrovascular bypass surgery in the treatment of residual or recurrent aneurysms after embolization at the authors' institution from 2018 to 2022. Results: The Glasgow Outcome Scale of 28 patients after the procedure and at discharge showed that 24 recovered well, 3 had severe disability, and 1 died. During the 24-month follow-up, 26 had a good recovery, 1 suffered from disability, and 1 died. Two cases of aneurysm recurrence were detected, and both were treated through endovascular therapy. Among them, 1 case underwent a repeat endovascular embolization, and 1 case was switched to surgical clipping. No residual aneurysms were observed in the remaining patients who underwent bypass surgery, and their bypass grafts were all patent. Conclusion: Based on the clinical status of patients, aneurysmal characteristics, surgical risk, and possibility of rerupture of aneurysms, an individualized strategy was proposed for residual or recurrent aneurysms after embolization. The use of endovascular interventional therapy or surgical clipping can be safely and effectively managed, and cerebrovascular bypass surgery can effectively manage complex aneurysms.
Language	English
Publishing date	2024-05-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000010140
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Article ; Online: Improved Skip-Gram Based on Graph Structure Information.

Wang, Xiaojie / Zhao, Haijun / Chen, Huayue

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 14

Abstract: Applying the Skip-gram to graph representation learning has become a widely researched topic in recent years. Prior works usually focus on the migration application of the Skip-gram model, while Skip-gram in graph representation learning, initially ... ...

Abstract	Applying the Skip-gram to graph representation learning has become a widely researched topic in recent years. Prior works usually focus on the migration application of the Skip-gram model, while Skip-gram in graph representation learning, initially applied to word embedding, is left insufficiently explored. To compensate for the shortcoming, we analyze the difference between word embedding and graph embedding and reveal the principle of graph representation learning through a case study to explain the essential idea of graph embedding intuitively. Through the case study and in-depth understanding of graph embeddings, we propose Graph Skip-gram, an extension of the Skip-gram model using graph structure information. Graph Skip-gram can be combined with a variety of algorithms for excellent adaptability. Inspired by word embeddings in natural language processing, we design a novel feature fusion algorithm to fuse node vectors based on node vector similarity. We fully articulate the ideas of our approach on a small network and provide extensive experimental comparisons, including multiple classification tasks and link prediction tasks, demonstrating that our proposed approach is more applicable to graph representation learning.
Language	English
Publishing date	2023-07-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23146527
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Article: MiR-124-3p Suppresses the Dysfunction of High Glucose-Stimulated Endothelial Cells by Targeting G3BP2.

Zhao, Haijun / He, Yanhui

Frontiers in genetics

2021 Volume 12, Page(s) 723625

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-10-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2021.723625
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Article: The Inhibitory Effect of Lysophosphatidylcholine on Proangiogenesis of Human CD34

Zhao, Haijun / He, Yanhui

Frontiers in molecular biosciences

2021 Volume 8, Page(s) 682367

Abstract: Increasing evidence reveals that lysophosphatidylcholine (LPC) is closely related to endothelial dysfunction. The present study aimed to investigate the mechanism of LPC in inhibiting the proangiogenesis and vascular inflammation of human endothelial ... ...

Abstract	Increasing evidence reveals that lysophosphatidylcholine (LPC) is closely related to endothelial dysfunction. The present study aimed to investigate the mechanism of LPC in inhibiting the proangiogenesis and vascular inflammation of human endothelial progenitor cells (EPCs) derived from CD34
Language	English
Publishing date	2021-06-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2814330-9
ISSN	2296-889X
ISSN	2296-889X
DOI	10.3389/fmolb.2021.682367
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Article ; Online: Lysophosphatidylcholine Offsets the Protective Effects of Bone Marrow Mesenchymal Stem Cells on Inflammatory Response and Oxidative Stress Injury of Retinal Endothelial Cells via TLR4/NF-

Zhao, Haijun / He, Yanhui

Journal of immunology research

2021 Volume 2021, Page(s) 2389029

Abstract: Diabetic retinopathy (DR), as a major cause of blindness worldwide, is one common complication of diabetes mellitus. Inflammatory response and oxidative stress injury of endothelial cells play significant roles in the pathogenesis of DR. The study is ... ...

Abstract	Diabetic retinopathy (DR), as a major cause of blindness worldwide, is one common complication of diabetes mellitus. Inflammatory response and oxidative stress injury of endothelial cells play significant roles in the pathogenesis of DR. The study is aimed at investigating the effects of lysophosphatidylcholine (LPC) on the dysfunction of high glucose- (HG-) treated human retinal microvascular endothelial cells (HRMECs) after being cocultured with bone marrow mesenchymal stem cells (BMSCs) and the underlying regulatory mechanism. Coculture of BMSCs and HRMECs was performed in transwell chambers. The activities of antioxidant-related enzymes and molecules of oxidative stress injury and the contents of inflammatory cytokines were measured by ELISA. Flow cytometry analyzed the apoptosis of treated HRMECs. HRMECs were further treated with 10-50
MeSH term(s)	Cells, Cultured ; Coculture Techniques ; Diabetic Retinopathy/immunology ; Diabetic Retinopathy/therapy ; Endothelial Cells/immunology ; Endothelial Cells/pathology ; Humans ; Lysophosphatidylcholines/metabolism ; Mesenchymal Stem Cell Transplantation ; Mesenchymal Stem Cells/immunology ; NF-kappa B/metabolism ; Oxidative Stress/immunology ; Primary Cell Culture ; Retina/cytology ; Retina/immunology ; Retina/pathology ; Signal Transduction/immunology ; Toll-Like Receptor 4/metabolism
Chemical Substances	Lysophosphatidylcholines ; NF-kappa B ; TLR4 protein, human ; Toll-Like Receptor 4
Language	English
Publishing date	2021-10-14
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2817541-4
ISSN	2314-7156 ; 2314-7156
ISSN (online)	2314-7156
ISSN	2314-7156
DOI	10.1155/2021/2389029
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Article ; Online: In five wastewater treatment plants in Xinjiang, China: Removal processes for illicit drugs, their occurrence in receiving river waters, and ecological risk assessment.

Zhao, Jie / Lu, Jianjiang / Zhao, Haijun / Yan, Yujun / Dong, Hongyu

Chemosphere

2023 Volume 339, Page(s) 139668

Abstract: Residues of illicit drugs are frequently detected in wastewater, but data on their removal efficiency by wastewater treatment plants (WWTPs) and the ecological risks to the aquatic environment are lacking in this study. The research evaluates the ... ...

Abstract	Residues of illicit drugs are frequently detected in wastewater, but data on their removal efficiency by wastewater treatment plants (WWTPs) and the ecological risks to the aquatic environment are lacking in this study. The research evaluates the residues, mass load, drug removal efficiency, and risk assessment of illicit drugs in WWTPs and aquatic environments (lakes) in Xinjiang, China. Initially, the concentration (incidence) and mass load of 10 selected illicit drugs were analyzed through wastewater analysis. The detected substances included methamphetamine (METH), morphine (MOR), 3,4-methylenedioxy methamphetamine (MDMA), methadone (MTD), cocaine (COC), benzoylecgonine (BE), ketamine (KET), and codeine (COD), with concentrations ranging from 0.11 ± 0.01 ng/L (methadone) to 48.26 ± 25.05 ng/L (morphine). Notably, morphine (59.74 ± 5.82 g/day) and methamphetamine (41.81 ± 4.91 g/day) contributed significantly to the WWTPs. Next, the drug removal efficiency by different sewage treatment processes was ranked as follows: Anaerobic-Oxic (A/O) combined Membrane Bio-Reactor (MBR) treatment process > Oxidation ditch treatment process > Anaerobic-Anoxic-Oxic (A2/O) treatment process > Anaerobic-Anoxic-Oxic combined Membrane Bio-Reactor treatment process. Finally, the research reviewed the concentration and toxicity assessments of these substances in the aquatic environment (lakes). The results indicated that Lake1 presented a medium risk level concerning the impact of illicit drugs on the aquatic environment, whereas the other lakes exhibited a low risk level. As a result, it is recommended to conduct long-term monitoring and source analysis of illicit drugs, specifically in Lake1, for further investigation. In conclusion, to enhance the understanding of the effects of illicit drugs on the environment, future research should expand the list of target analytes.
MeSH term(s)	Wastewater ; Waste Disposal, Fluid/methods ; Illicit Drugs/analysis ; Rivers ; Water Pollutants, Chemical/analysis ; Methamphetamine/analysis ; Water Purification/methods ; Risk Assessment ; Morphine Derivatives/analysis ; China
Chemical Substances	Wastewater ; Illicit Drugs ; Water Pollutants, Chemical ; Methamphetamine (44RAL3456C) ; Morphine Derivatives
Language	English
Publishing date	2023-07-28
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2023.139668
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Article: Experimental research on deformation failure process of roadway tunnel in fractured rock mass induced by mining excavation.

Li, Guang / Ma, Fengshan / Guo, Jie / Zhao, Haijun

Environmental earth sciences

2022 Volume 81, Issue 8, Page(s) 243

Abstract: Deformation failure of roadways in fractured rock can lead to large-volume collapse and other engineering accidents. Failure mechanisms in fractured rock are complex and poorly understood, so to explore this issue, we simulated fractured rock masses ... ...

Abstract	Deformation failure of roadways in fractured rock can lead to large-volume collapse and other engineering accidents. Failure mechanisms in fractured rock are complex and poorly understood, so to explore this issue, we simulated fractured rock masses using physical model tests in combination with numerical computations. A set of experimental techniques for roadway excavation under jointed surrounding rock included a mixed pouring-bricking method and a roadway excavation device, which can reproduce the structural characteristics of the prototype and replicate the excavation conditions of the roadway. Stress distribution characteristics of the roadway, from loading to excavation, were obtained based on strain monitoring and image acquisition, and the process of roadway deformation and failure was described in detail. A series of numerical simulations were conducted to investigate the deformation failure mechanisms of roadways under different excavation conditions. Results indicate that the deformation failure modes of roadways including collapse, rock burst, and floor heaving that were similar regardless of depth. Deformation failure modes of the roadway were determined by rock mass structure, and the deformation intensity was determined by geo-stress. Model testing and numerical simulation were consistent; hence, findings provide a theoretical basis and technical guidance for roadway engineering in fractured rock masses.
Language	English
Publishing date	2022-04-13
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2493699-6
ISSN	1866-6299 ; 1866-6280
ISSN (online)	1866-6299
ISSN	1866-6280
DOI	10.1007/s12665-022-10364-2
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Article ; Online: Analysis, occurrence, and consumption of substances with abuse potential in Xinjiang, China, from 2021 to 2022

Zhao, Jie / Lu, Jianjiang / Zhao, Haijun / Yan, Yujun / Dong, Hongyu / Li, Wen

Science of the Total Environment. 2023 Sept., v. 889 p.164310-

2023

Abstract: Understanding the consumption patterns of substances with abuse potential in the population is critical in combating drug crimes in the region. In recent years, wastewater-based drug monitoring has become a complementary tool worldwide. This study aimed ... ...

Abstract	Understanding the consumption patterns of substances with abuse potential in the population is critical in combating drug crimes in the region. In recent years, wastewater-based drug monitoring has become a complementary tool worldwide. This study aimed to use this approach to understand the long-term consumption patterns of abuse potential substances in Xinjiang, China (2021–2022) and to provide more detailed and practical information on the current system. High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was employed to quantify the levels of abuse potential substances in wastewater. Subsequently, the detection rate and contribution rate of the drug concentrations were evaluated through analysis. Eleven of abuse potential substances were detected in this study. The influent concentrations ranged from (0.48 ng/L) to 133.41 ng/L, with dextrorphan having the highest concentration. The highest detection frequency rates were for morphine (82 %), dextrorphan (59 %), 11-nor-Δ⁹-tetrahydrocannabinol-9-carboxylic acid (43 %), methamphetamine (36 %), and tramadol (24 %). According to a study on wastewater treatment plants (WWTPs) removal efficiency, compared to the total removal efficiency in 2021, the total removal efficiency of WWTP1, WWTP3, and WWTP4 increased in 2022, while WWTP2 decreased slightly, and WWTP5 did not change significantly. Upon examination of the use of 18 selected analytes, it was determined that methadone, 3,4-methylenedioxy methamphetamine, ketamine, and cocaine were the primary substances of abuse in the Xinjiang region. This study identified significant abuse substances in Xinjiang and identified research priorities. Future studies should consider expanding the study site to obtain a comprehensive understanding of the consumption patterns of these substances in Xinjiang.
Keywords	chemical species ; cocaine ; environment ; ketamine ; liquid chromatography ; methadone ; methamphetamines ; morphine ; tandem mass spectrometry ; wastewater ; wastewater treatment ; China ; Substances with abuse potential ; Removal efficiency ; Occurrence and consumption
Language	English
Dates of publication	2023-09
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.164310
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