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  1. Article ; Online: Integration Analysis of Hair Follicle Transcriptome and Proteome Reveals the Mechanisms Regulating Wool Fiber Diameter in Angora Rabbits.

    Huang, Dongwei / Ding, Haisheng / Wang, Yuanlang / Wang, Xiaofei / Zhao, Huiling

    International journal of molecular sciences

    2024  Volume 25, Issue 6

    Abstract: Fiber diameter is an important characteristic that determines the quality and economic value of rabbit wool. This study aimed to investigate the genetic determinants of wool fiber diameter through an integration analysis using transcriptomic and ... ...

    Abstract Fiber diameter is an important characteristic that determines the quality and economic value of rabbit wool. This study aimed to investigate the genetic determinants of wool fiber diameter through an integration analysis using transcriptomic and proteomic datasets from hair follicles of coarse and fine wool from Angora rabbits. Using a 4D label-free technique, we identified 423 differentially expressed proteins (DEPs) in hair follicles of coarse and fine wool in Angora rabbits. Eighteen DEPs were examined using parallel reaction monitoring, which verified the reliability of our proteomic data. Functional enrichment analysis revealed that a set of biological processes and signaling pathways related to wool growth and hair diameter were strongly enriched by DEPs with fold changes greater than two, such as keratinocyte differentiation, skin development, epidermal and epithelial cell differentiation, epidermis and epithelium development, keratinization, and estrogen signaling pathway. Association analysis and protein-protein interaction network analysis further showed that the keratin (KRT) family members, including KRT77, KRT82, KRT72, KRT32, and KRT10, as well as CASP14 and CDSN, might be key factors contributing to differences in fiber diameter. Our results identified DEPs in hair follicles of coarse and fine wool and promoted understanding of the molecular mechanisms underlying wool fiber diameter variation among Angora rabbits.
    MeSH term(s) Animals ; Rabbits ; Hair Follicle/metabolism ; Transcriptome ; Wool Fiber ; Proteome/genetics ; Proteome/metabolism ; Proteomics ; Reproducibility of Results ; Wool/physiology
    Chemical Substances Proteome
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25063260
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ultra-High Temperature Operated Ni-Rich Cathode Stabilized by Thermal Barrier for High-Energy Lithium-Ion Batteries.

    Dai, Zhongsheng / Liu, Yun / Lu, Xia / Zhao, Huiling / Bai, Ying

    Advanced materials (Deerfield Beach, Fla.)

    2024  , Page(s) e2313500

    Abstract: The pursuit of high energy density batteries has expedited the fast development of Ni-rich cathodes. However, the chemo-mechanical degradation induced by local thermal accumulation and anisotropic lattice strain is posing great obstacles for its wide ... ...

    Abstract The pursuit of high energy density batteries has expedited the fast development of Ni-rich cathodes. However, the chemo-mechanical degradation induced by local thermal accumulation and anisotropic lattice strain is posing great obstacles for its wide applications. Herein, a highly-antioxidative BaZrO
    Language English
    Publishing date 2024-03-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202313500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Blood scab caused airway obstruction - Postoperative care also needs to be considered as a complication.

    Chen, Siwen / Fu, Xing / Yu, Rong / Zhao, Huiling

    Asian journal of surgery

    2023  Volume 46, Issue 10, Page(s) 4422–4424

    MeSH term(s) Humans ; Postoperative Care/adverse effects ; Airway Obstruction/diagnosis ; Airway Obstruction/etiology ; Tracheal Stenosis/etiology ; Postoperative Complications/etiology ; Postoperative Complications/therapy
    Language English
    Publishing date 2023-05-13
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.04.077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Trifunctional Rb

    Wang, Kai / Li, Shijia / Chen, Xue / Shen, Jiasen / Zhao, Huiling / Bai, Ying

    ACS nano

    2024  Volume 18, Issue 9, Page(s) 7311–7323

    Abstract: Rechargeable aqueous zinc-ion batteries (AZIBs) have been highly desired due to their low cost, intrinsic safety, environmental friendliness, and great potential in large-scale power storage systems. However, their practical applications are impeded by ... ...

    Abstract Rechargeable aqueous zinc-ion batteries (AZIBs) have been highly desired due to their low cost, intrinsic safety, environmental friendliness, and great potential in large-scale power storage systems. However, their practical applications are impeded by unstable long-term electrochemical performances induced by microstructure degradation of the cathode material, hydrogen evolution reaction in the electrolyte, and dendritic growth on the zinc anode upon cycling. In this work, rubidium cations (Rb
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.4c00803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Transcriptome analysis of divergent residual feed intake phenotypes in the

    Huang, Dongwei / Wang, Yuanlang / Qi, Pingping / Ding, Haisheng / Zhao, Huiling

    Frontiers in genetics

    2023  Volume 14, Page(s) 1247048

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-10-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1247048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Syntheses, crystal structure, and photoelectric properties of two Zn-based chalcogenidoantimonates Zn-Sb-Q (Q = S, Se).

    Zhang, Lirong / Zhao, Huiling / Liu, Xin / Teri, Gele / Baiyin, Menghe

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 43, Page(s) 29709–29717

    Abstract: Metal chalcogenides are a special class of semiconducting materials characterized by their rich structures and compositions, making them a promising option for a broad range of applications in the field of inorganic chemistry. However, the path forward ... ...

    Abstract Metal chalcogenides are a special class of semiconducting materials characterized by their rich structures and compositions, making them a promising option for a broad range of applications in the field of inorganic chemistry. However, the path forward is not without its challenges, notably in the realms of interface management and enhancing carrier concentration. To address these issues, we solvothermally synthesized two novel chalcogenidoantimonates [Zn(tren)]
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp04074g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Surface Coupling between Mechanical and Electric Fields Empowering Ni-Rich Cathodes with Superior Cyclabilities for Lithium-Ion Batteries.

    Dai, Zhongsheng / Wang, Jianhang / Zhao, Huiling / Bai, Ying

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2022  Volume 9, Issue 18, Page(s) e2200622

    Abstract: Ni-rich cathodes with high energy densities are considered as promising candidates for advanced lithium-ion batteries, whereas their commercial application is in dilemma due to dramatic capacity decay and poor structure stability stemmed from interfacial ...

    Abstract Ni-rich cathodes with high energy densities are considered as promising candidates for advanced lithium-ion batteries, whereas their commercial application is in dilemma due to dramatic capacity decay and poor structure stability stemmed from interfacial instability, structural degradation, and stress-strain accumulation, as well as intergranular cracks. Herein, a piezoelectric LiTaO
    Language English
    Publishing date 2022-04-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202200622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Novel optimal trajectory tracking for nonlinear affine systems with an advanced critic learning structure.

    Wang, Ding / Zhao, Huiling / Zhao, Mingming / Ren, Jin

    Neural networks : the official journal of the International Neural Network Society

    2022  Volume 154, Page(s) 131–140

    Abstract: In this paper, a critic learning structure based on the novel utility function is developed to solve the optimal tracking control problem with the discount factor of affine nonlinear systems. The utility function is defined as the quadratic form of the ... ...

    Abstract In this paper, a critic learning structure based on the novel utility function is developed to solve the optimal tracking control problem with the discount factor of affine nonlinear systems. The utility function is defined as the quadratic form of the error at the next moment, which can not only avoid solving the stable control input, but also effectively eliminate the tracking error. Next, the theoretical derivation of the method under value iteration is given in detail with convergence and stability analysis. Then, the dual heuristic dynamic programming (DHP) algorithm via a single neural network is introduced to reduce the amount of computation. The polynomial is used to approximate the costate function during the DHP implementation. The weighted residual method is used to update the weight matrix. During simulation, the convergence speed of the given strategy is compared with the heuristic dynamic programming (HDP) algorithm. The experiment results display that the convergence speed of the proposed method is faster than the HDP algorithm. Besides, the proposed method is compared with the traditional tracking control approach to verify its tracking performance. The experiment results show that the proposed method can avoid solving the stable control input, and the tracking error is closer to zero than the traditional strategy.
    MeSH term(s) Algorithms ; Computer Simulation ; Learning ; Neural Networks, Computer ; Nonlinear Dynamics
    Language English
    Publishing date 2022-07-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 740542-x
    ISSN 1879-2782 ; 0893-6080
    ISSN (online) 1879-2782
    ISSN 0893-6080
    DOI 10.1016/j.neunet.2022.07.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Hair Follicle Transcriptome Analysis Reveals Differentially Expressed Genes That Regulate Wool Fiber Diameter in Angora Rabbits

    Huang, Dongwei / Ding, Haisheng / Wang, Yuanlang / Cheng, Guanglong / Wang, Xiaofei / Leng, Taishan / Zhao, Huiling

    Biology (Basel). 2023 Mar. 14, v. 12, no. 3

    2023  

    Abstract: Wool fiber diameter (WFD) is an important index of wool traits and the main determinant of wool quality and value. However, the genetic determinants of fiber diameter have not yet been fully elucidated. Here, coarse and fine wool of Wan strain Angora ... ...

    Abstract Wool fiber diameter (WFD) is an important index of wool traits and the main determinant of wool quality and value. However, the genetic determinants of fiber diameter have not yet been fully elucidated. Here, coarse and fine wool of Wan strain Angora rabbits and their hair follicle traits were characterized. The results indicated significant differences in the diameters of wool fibers and their hair follicles. The RNA sequencing (RNA-Seq) technique was used to identify differences in gene expression in hair follicles between coarse and fine wool. In total, 2574 differentially expressed genes (DEGs) were found between the two hair follicle groups. Transcription factors, keratin-associated protein (KAP) and keratin (KRT) families, and ECM-related genes may control the structure of fine fibers in rabbits. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses revealed that skin development, epidermal cell and keratinocyte differentiation, epithelium development, and Notch and ribosome signaling pathways were significantly enriched, respectively. GSEA further filtered six important pathways and related core genes. PPI analysis also mined functional DEGs associated with hair structure, including LEF1, FZD3, SMAD3, ITGB6, and BMP4. Our findings provide valuable information for researching the molecular mechanisms regulating wool fiber and could facilitate enhanced selection of super-fine wool rabbits through gene-assisted selection in the future.
    Keywords RNA ; epithelium ; gene expression ; gene expression regulation ; gene ontology ; genome ; hair follicles ; keratin ; keratinocytes ; ribosomes ; sequence analysis ; transcriptomics ; wool
    Language English
    Dates of publication 2023-0314
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12030445
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Hair Follicle Transcriptome Analysis Reveals Differentially Expressed Genes That Regulate Wool Fiber Diameter in Angora Rabbits.

    Huang, Dongwei / Ding, Haisheng / Wang, Yuanlang / Cheng, Guanglong / Wang, Xiaofei / Leng, Taishan / Zhao, Huiling

    Biology

    2023  Volume 12, Issue 3

    Abstract: Wool fiber diameter (WFD) is an important index of wool traits and the main determinant of wool quality and value. However, the genetic determinants of fiber diameter have not yet been fully elucidated. Here, coarse and fine wool of Wan strain Angora ... ...

    Abstract Wool fiber diameter (WFD) is an important index of wool traits and the main determinant of wool quality and value. However, the genetic determinants of fiber diameter have not yet been fully elucidated. Here, coarse and fine wool of Wan strain Angora rabbits and their hair follicle traits were characterized. The results indicated significant differences in the diameters of wool fibers and their hair follicles. The RNA sequencing (RNA-Seq) technique was used to identify differences in gene expression in hair follicles between coarse and fine wool. In total, 2574 differentially expressed genes (DEGs) were found between the two hair follicle groups. Transcription factors, keratin-associated protein (KAP) and keratin (KRT) families, and ECM-related genes may control the structure of fine fibers in rabbits. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses revealed that skin development, epidermal cell and keratinocyte differentiation, epithelium development, and Notch and ribosome signaling pathways were significantly enriched, respectively. GSEA further filtered six important pathways and related core genes. PPI analysis also mined functional DEGs associated with hair structure, including
    Language English
    Publishing date 2023-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12030445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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