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  1. Article: [Study on the mechanism of cross-linked hyaluronic acid-dexamethasone hydrogelin post-traumatic osteoarthritis].

    Zhang, Z W / Zhao, J Y / Feng, Y / Yin, K / Li, P C / Wei, X C

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 9, Page(s) 695–703

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Rats ; Animals ; Hyaluronic Acid/pharmacology ; Matrix Metalloproteinase 3/pharmacology ; Matrix Metalloproteinase 13/metabolism ; Matrix Metalloproteinase 13/pharmacology ; Interleukin-6 ; Tumor Necrosis Factor-alpha/metabolism ; Rats, Sprague-Dawley ; Osteoarthritis/metabolism ; Cartilage, Articular/metabolism ; Cartilage, Articular/pathology ; Inflammation ; Chondrocytes ; Dexamethasone/pharmacology ; Hydrogels/pharmacology ; RNA, Messenger
    Chemical Substances Hyaluronic Acid (9004-61-9) ; Matrix Metalloproteinase 3 (EC 3.4.24.17) ; Matrix Metalloproteinase 13 (EC 3.4.24.-) ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Dexamethasone (7S5I7G3JQL) ; Hydrogels ; RNA, Messenger
    Language Chinese
    Publishing date 2024-02-28
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20231008-00672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article: [Value of hypoxic burden in evaluating the impairments of organ systems in obstructive sleep apnea].

    Wang, X / Zhao, J Y / Yuan, H B

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2022  Volume 45, Issue 6, Page(s) 609–613

    Abstract: Obstructive sleep apnea (OSA) is a common sleep-disordered-breathing with decreased or even suspended ventilation due to upper airway obstruction, which is characterized by intermittent hypoxia and sleep fragmentation. OSA can damage a variety of organ ... ...

    Abstract Obstructive sleep apnea (OSA) is a common sleep-disordered-breathing with decreased or even suspended ventilation due to upper airway obstruction, which is characterized by intermittent hypoxia and sleep fragmentation. OSA can damage a variety of organ systems, especially the cardiovascular system, seriously affecting the quality of life of patients. Therefore, more attention is paid to the precise assessment of the impairments of the organ systems caused by OSA and the evaluation of indicators, in order to carry out preventive measures as soon as possible. However, due to the limitations of traditional indicators such as apnea-hypopnea index (AHI) in assessing the severity of disease, it is necessary to explore other alternative indicators to obtain multi-dimensional characteristics of OSA. A promising parameter, hypoxic burden (HB) can better quantify the severity of OSA and capture the disease load of OSA. This review mainly focused on the basic concept, main features, calculating method of HB and its clinical significance in predicting the adverse consequences of OSA, aiming at a better management of patients with OSA.
    MeSH term(s) Humans ; Hypoxia ; Quality of Life ; Sleep Apnea Syndromes ; Sleep Apnea, Obstructive
    Language Chinese
    Publishing date 2022-05-31
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    DOI 10.3760/cma.j.cn112147-20220315-00206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Notch1 inhibits the mechanistic role of STING signaling to regulate hepatocyte lipophagy in nonalcoholic steatohepatitis].

    Yang, T / Zhao, J Y / Wang, X / Fang, Z G / Jiang, L F / Li, J

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2023  Volume 31, Issue 8, Page(s) 827–834

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Animals ; Mice ; Autophagy ; Hepatocytes ; Non-alcoholic Fatty Liver Disease ; Signal Transduction ; Tumor Necrosis Factor-alpha ; Receptor, Notch1/metabolism ; Membrane Proteins/metabolism
    Chemical Substances favipiravir (EW5GL2X7E0) ; Tumor Necrosis Factor-alpha ; Notch1 protein, mouse ; Sting1 protein, mouse ; Receptor, Notch1 ; Membrane Proteins
    Language Chinese
    Publishing date 2023-09-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20230208-00042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Analysis on academic quality and influence of

    Wan, Y L / Dou, Z / Zhao, J Y / Wang, L

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2021  Volume 42, Issue 6, Page(s) 1128–1132

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Bibliometrics ; China/epidemiology ; Humans
    Language Chinese
    Publishing date 2021-11-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20210519-00410
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Progress in research of genomic epidemiology of pathogenic fungi].

    Zhong, H Y / Li, D C / Chen, F Y / Zhao, J Y / Xu, R / Han, L

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2022  Volume 43, Issue 6, Page(s) 981–986

    Abstract: Genomic epidemiology, based on whole-genome sequencing technology and bioinformatics analysis, can make up for the shortcomings of traditional molecular typing methods and provide a novel insight for the genetic evolution and transmission of pathogenic ... ...

    Abstract Genomic epidemiology, based on whole-genome sequencing technology and bioinformatics analysis, can make up for the shortcomings of traditional molecular typing methods and provide a novel insight for the genetic evolution and transmission of pathogenic fungi. The combination of genetic information and epidemiological methods of pathogenic fungi can predict fungi transmission routes and risks, and provide a theoretical basis for the development of public health strategies for fungi infection prevention and control. This paper summarizes the development of molecular epidemiology and genomic epidemiology, as well as the application of genomic epidemiology methods in the analyses of genetic relationship, origin, evolution, drug resistance, virulence, and genome-wide association of pathogenic fungi, and discusses the development of pathogenic fungi genomic epidemiology.
    MeSH term(s) Fungi/genetics ; Genome-Wide Association Study ; Genomics/methods ; Humans ; Molecular Epidemiology/methods ; Molecular Typing
    Language Chinese
    Publishing date 2022-06-20
    Publishing country China
    Document type Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20211015-00794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Prognostic factors for non-small cell lung cancer patients with central nervous system metastasis with positive driver genes].

    Li, R / Zhang, S R / Liu, X F / Zhang, J W / Zhao, J Y / Bai, P / Zhang, X C

    Zhonghua yi xue za zhi

    2023  Volume 103, Issue 16, Page(s) 1202–1209

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Female ; Humans ; Middle Aged ; Aged ; Carcinoma, Non-Small-Cell Lung/genetics ; Prognosis ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Retrospective Studies ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Central Nervous System Neoplasms ; Brain/pathology
    Language Chinese
    Publishing date 2023-04-22
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20221028-02243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [The key points in intravenous chemotherapy and intra-arterial chemotherapy on retinoblastoma treatment].

    Zhao, J Y / Zhang, C Y

    Zhonghua yan ke za zhi] Chinese journal of ophthalmology

    2017  Volume 53, Issue 8, Page(s) 566–569

    Abstract: Intravenous chemotherapy and intra-arterial chemotherapy (IAC) both are the first-line treatment for retinoblastoma (RB) in clinical. There is a controversy on if intra-arterial chemotherapy can substitute the intravenous chemotherapy due to its high eye ...

    Abstract Intravenous chemotherapy and intra-arterial chemotherapy (IAC) both are the first-line treatment for retinoblastoma (RB) in clinical. There is a controversy on if intra-arterial chemotherapy can substitute the intravenous chemotherapy due to its high eye salvage rate in retinoblastoma therapy. The advantages and disadvantages of these two therapies were retrospectively reviewed here to suggest an individualized and comprehensive regimen for getting the proximal results for retinoblastoma afflicted children.
    MeSH term(s) Antineoplastic Agents/administration & dosage ; Child ; Humans ; Infant ; Infusions, Intra-Arterial ; Ophthalmic Artery ; Retinal Neoplasms/drug therapy ; Retinoblastoma/drug therapy ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Antineoplastic Agents
    Language Chinese
    Publishing date 2017-08-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 604574-1
    ISSN 0412-4081
    ISSN 0412-4081
    DOI 10.3760/cma.j.issn.0412-4081.2017.08.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2482: Show issues Location:
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    Zs.MO 267: Show issues

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  8. Article: [Evaluation of the clinical manifestations of COVID-19 in patients with aplastic anemia undergoing immunosuppressive therapy: a prospective cohort study (NICHE)].

    Zhao, J Y / Zhang, L L / Kuang, Z X / Xu, J / Wang, W W / Pan, H / Gao, Z / Li, W W / Fang, L W / Song, Z / Shi, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2024  Volume 44, Issue 11, Page(s) 900–905

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Anemia, Aplastic ; COVID-19 ; Prospective Studies ; Fever ; Immunosuppression Therapy ; Pharyngitis
    Language Chinese
    Publishing date 2024-01-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2023.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Efficacy and safety analysis of venetoclax combined with hypomethylating agents for the treatment of higher-risk myelodysplastic syndromes in the real world].

    Gao, Q Y / Li, B / Qu, S Q / Pan, L J / Jiao, M / Zhao, J Y / Xu, Z F / Xiao, Z J / Qin, T J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2024  Volume 45, Issue 2, Page(s) 156–162

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Retrospective Studies ; Prognosis ; Myelodysplastic Syndromes/genetics ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Sulfonamides
    Chemical Substances venetoclax (N54AIC43PW) ; Bridged Bicyclo Compounds, Heterocyclic ; Sulfonamides
    Language Chinese
    Publishing date 2024-04-11
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.cn121090-20230926-00136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Progress in research of economic evaluation of non-pharmaceutical interventions for COVID-19 prevention and control].

    Fu, Y Q / Zhao, J Y / Han, P E / Yang, L / Ren, S Y / Zhan, L M / Li, Liming

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2022  Volume 43, Issue 7, Page(s) 1030–1037

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) COVID-19/prevention & control ; Communicable Disease Control/methods ; Cost-Benefit Analysis ; Humans ; Nucleic Acids ; SARS-CoV-2
    Chemical Substances Nucleic Acids
    Language Chinese
    Publishing date 2022-07-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20220218-00129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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