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  1. Article ; Online: Oncologic Safety of One-Stage Implant-Based Breast Reconstruction in Breast Cancer Patients With Positive Sentinel Lymph Nodes: A Single-Center Retrospective Study Using Propensity Score Matching.

    Zhao, Jingjing / Xiao, Chunhua

    Clinical breast cancer

    2023  Volume 24, Issue 1, Page(s) e1–e8

    Abstract: Objective: The purpose of this study is to evaluate the oncologic safety of one-stage implant-based breast reconstruction (OIBR) following mastectomy in breast cancer patients with positive sentinel lymph nodes (SLNs).: Methods: We collected clinical ...

    Abstract Objective: The purpose of this study is to evaluate the oncologic safety of one-stage implant-based breast reconstruction (OIBR) following mastectomy in breast cancer patients with positive sentinel lymph nodes (SLNs).
    Methods: We collected clinical and pathological data from breast cancer patients with positive SLNs who underwent OIBR or not after mastectomy between January 2015 and December 2018. A total of 194 patients were included, with 130 patients undergoing mastectomy alone (MA) and 64 patients receiving OIBR after mastectomy. The clinical and pathological features, as well as the postoperative oncologic outcomes, of the 2 groups were retrospectively analyzed. Propensity score matching (PSM) was employed to mitigate the effects of data bias and confounding factors.
    Results: The median follow-up time was 66 months for the OIBR group and 64 months for the MA group after PSM. The majority of reconstructive surgeries use an approach of prosthetic implantation (52.0%). This is followed by prosthetic implantation combined with a latissimus dorsi (LD) flap (32.0%), and acellular dermal matrix (ADM)-assisted implant placement (16.0%). During the follow-up period, a local recurrence was observed in 1 case, regional recurrence in 3 cases, and distant metastasis leading to death in 3 cases among the OIBR group patients. No significant difference was found between the OIBR and MA groups in disease-free survival (DFS) (P = .66), distant metastasis-free survival (DMFS) (P = .91), locoregional recurrence-free survival (LRRFS) (P = .44), and overall survival (OS) (P = .57).
    Conclusion: OIBR is a safe option for breast cancer patients with positive SLNs and does not negatively impact cancer recurrence or overall survival.
    MeSH term(s) Humans ; Female ; Breast Neoplasms/pathology ; Mastectomy ; Retrospective Studies ; Sentinel Lymph Node/surgery ; Sentinel Lymph Node/pathology ; Propensity Score ; Neoplasm Recurrence, Local/pathology ; Mammaplasty ; Lymph Nodes/surgery ; Lymph Nodes/pathology
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2106734-X
    ISSN 1938-0666 ; 1526-8209
    ISSN (online) 1938-0666
    ISSN 1526-8209
    DOI 10.1016/j.clbc.2023.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How rumination influences meaning in life among Chinese high school students: the mediating effects of perceived chronic social adversity and coping style.

    Yu, Xiaolin / Zhao, Jingjing

    Frontiers in public health

    2023  Volume 11, Page(s) 1280961

    Abstract: Meaning in life can be affected by many factors during adolescence. This study explored the relationship between rumination and meaning in life among high school students, as well as the mediating effect of perceived chronic social adversity and coping ... ...

    Abstract Meaning in life can be affected by many factors during adolescence. This study explored the relationship between rumination and meaning in life among high school students, as well as the mediating effect of perceived chronic social adversity and coping style. A sample of 1,275 Chinese high school students were surveyed using four questionnaires. Data analysis was conducted using Harman's single-factor test, Pearson's correlation coefficient with confidence intervals (CI), and a structural equation model. We found that rumination significantly negatively affected meaning in life among high school students (
    MeSH term(s) Adolescent ; Humans ; Adaptation, Psychological ; Social Alienation ; Students ; Coping Skills ; China
    Language English
    Publishing date 2023-12-01
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1280961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A 12 Week Fetus with Anophthalmia, Limb Anomalies and Infratemporal Teratoma.

    Lu, Yu / Zhao, Jing-Jing / He, Ping

    International journal of women's health

    2024  Volume 16, Page(s) 41–46

    Abstract: Background: Microphthalmia is a rare autosomal recessive condition commonly known as Waardenburg anophthalmia syndrome (WAS) or oculo-acromal formation syndrome (MIM#206920).: Case description: Here, we report the case of a woman whose fetal ... ...

    Abstract Background: Microphthalmia is a rare autosomal recessive condition commonly known as Waardenburg anophthalmia syndrome (WAS) or oculo-acromal formation syndrome (MIM#206920).
    Case description: Here, we report the case of a woman whose fetal ultrasonography at 12 weeks of pregnancy revealed multiple fetal abnormalities. These included the absence of the left upper limb, an unclear display of the right orbit, a visible maxillary space, and a round, echoless appearance measuring 4 mm in diameter in the middle of the forehead. There was also a significant echo in the sac wall. The possibility of a frontal meningocele or a proboscis-like nose was considered. The fetus was delivered with absence of the left upper limb, absence of the right eye, a cleft lip on the right side, and a milky white sac with a diameter of 5 mm on the forehead after the pregnancy was terminated at the hospital. Pathological investigation revealed a mature cystic teratoma. The conclusion was microphthalmia with limb anomalies (MLA) after missing limbs, absence of eyes, and cleft lip were input into the Online Mendelian Inheritance in Man database. The case was diagnosed with fetal microphthalmia with limb anomalies and an interfrontal teratoma.
    Conclusion: In this case, the entire exon analysis was not conducted, and as a result, the final diagnosis remains unclear. Based exclusively on the phenotype of the induced fetus, MLA was diagnosed. It is proposed that cases satisfying the requirements for a pathological diagnosis should undergo a pathological examination to establish a definitive diagnosis.
    Language English
    Publishing date 2024-01-10
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2508161-5
    ISSN 1179-1411
    ISSN 1179-1411
    DOI 10.2147/IJWH.S441452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Exploring Circular RNA Profile and Expression in Extracellular Vesicles.

    Zhao, Jingjing / Li, Qiaojuan / Huang, Shenglin

    Methods in molecular biology (Clifton, N.J.)

    2024  Volume 2765, Page(s) 47–59

    Abstract: Extracellular vesicles (EVs) are small vesicles secreted by various cell types and are enriched in multiple body fluids. EVs containing RNA have the potential to modulate biological processes and are being investigated for their diagnostic and ... ...

    Abstract Extracellular vesicles (EVs) are small vesicles secreted by various cell types and are enriched in multiple body fluids. EVs containing RNA have the potential to modulate biological processes and are being investigated for their diagnostic and therapeutic applications. Circular RNAs (circRNAs), generated through back-splicing of exons, are enriched in EVs. Given their unique characteristics and diverse functions, EV-circRNAs are important players in disease pathology. This chapter describes a workflow for investigating the expression profile of EV-circRNAs, which includes EVs separation, library preparation, and bioinformatics analysis. This workflow can aid the investigation of EV-circRNAs and their potential role in disease pathology.
    MeSH term(s) RNA, Circular ; Extracellular Vesicles/genetics ; RNA/genetics ; Biological Transport ; Body Fluids
    Chemical Substances RNA, Circular ; RNA (63231-63-0)
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3678-7_3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The application and development of electron microscopy for three-dimensional reconstruction in life science: a review.

    Zhao, Jingjing / Yu, Xiaoping / Shentu, Xuping / Li, Danting

    Cell and tissue research

    2024  Volume 396, Issue 1, Page(s) 1–18

    Abstract: Imaging technologies have played a pivotal role in advancing biological research by enabling visualization of biological structures and processes. While traditional electron microscopy (EM) produces two-dimensional images, emerging techniques now allow ... ...

    Abstract Imaging technologies have played a pivotal role in advancing biological research by enabling visualization of biological structures and processes. While traditional electron microscopy (EM) produces two-dimensional images, emerging techniques now allow high-resolution three-dimensional (3D) characterization of specimens in situ, meeting growing needs in molecular and cellular biology. Combining transmission electron microscopy (TEM) with serial sectioning inaugurated 3D imaging, attracting biologists seeking to explore cell ultrastructure and driving advancement of 3D EM reconstruction. By comprehensively and precisely rendering internal structure and distribution, 3D TEM reconstruction provides unparalleled ultrastructural insights into cells and molecules, holding tremendous value for elucidating structure-function relationships and broadly propelling structural biology. Here, we first introduce the principle of 3D reconstruction of cells and tissues by classical approaches in TEM and then discuss modern technologies utilizing TEM and on new SEM-based as well as cryo-electron microscope (cryo-EM) techniques. 3D reconstruction techniques from serial sections, electron tomography (ET), and the recent single-particle analysis (SPA) are examined; the focused ion beam scanning electron microscopy (FIB-SEM), the serial block-face scanning electron microscopy (SBF-SEM), and automatic tape-collecting lathe ultramicrotome (ATUM-SEM) for 3D reconstruction of large volumes are discussed. Finally, we review the challenges and development prospects of these technologies in life science. It aims to provide an informative reference for biological researchers.
    MeSH term(s) Imaging, Three-Dimensional/methods ; Microscopy, Electron, Scanning ; Microscopy, Electron, Transmission ; Microtomy/methods ; Cryoelectron Microscopy
    Language English
    Publishing date 2024-02-28
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 125067-x
    ISSN 1432-0878 ; 0302-766X
    ISSN (online) 1432-0878
    ISSN 0302-766X
    DOI 10.1007/s00441-024-03878-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Prenatal diagnosis of a fetus with 1p36 deletion syndrome and 3p26.3p25.2 duplication].

    Zhao, Jingjing / Gao, Jingzhen / Zhao, Xiangyu / Li, Lin

    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

    2024  Volume 41, Issue 5, Page(s) 617–621

    Abstract: Objective: To explore the characteristics of a fetus with chromosome 1p36 deletion syndrome and 3p26.3p25.2 duplication.: Methods: A pregnant woman who had attended the Genetic Counseling Clinic of Linyi People's Hospital on February 22, 2022 and her ...

    Abstract Objective: To explore the characteristics of a fetus with chromosome 1p36 deletion syndrome and 3p26.3p25.2 duplication.
    Methods: A pregnant woman who had attended the Genetic Counseling Clinic of Linyi People's Hospital on February 22, 2022 and her fetus were selected as the study subjects. Clinical data were collected. Chromosomal karyotyping, fluorescence in situ hybridization (FISH) and chromosomal microarray analysis (CMA) were carried out for the prenatal diagnosis.
    Results: Ultrasonography at 24th gestational week revealed that the fetus had ventricular septal defect, single umbilical artery, and slight widening of left lateral ventricle (12 mm). The woman was found to have a karyotype of 46,XX,t(1;3)(p36.22;p25.2), and the result of FISH was t(1;3)(3pter+,1qter+;1pter+,3qter+). The fetus was found to have a karyotype of 46,X?,add(1)(p36), and CMA confirmed that it has a 9.0 Mb deletion at 1p36.33p36.22 and a 12.6 Mb duplication at 3p26.3p25.2. Combining the maternal karyotype, the molecular karyotype of the fetus was determined as 46,X?,der(1)t(1;3)(p36.22;p25.2)mat.arr[hg19]1p36.33p36.22(849467_9882666)×1, 3p26.3p25.2(61892_12699607)×3, with the former known to be associated with 1p36 deletion syndrome.
    Conclusion: The fetus was diagnosed with 1p36 deletion syndrome, and its 1p36.33p36.22 deletion and 3p26.3p25.2 duplication had both derived from the balanced translocation carried by its mother.
    MeSH term(s) Humans ; Female ; Chromosomes, Human, Pair 1/genetics ; Pregnancy ; Chromosome Deletion ; Prenatal Diagnosis ; Chromosomes, Human, Pair 3/genetics ; Chromosome Duplication ; Adult ; Karyotyping ; Trisomy/genetics ; Trisomy/diagnosis ; Chromosome Disorders/genetics ; Chromosome Disorders/embryology ; Chromosome Disorders/diagnosis ; In Situ Hybridization, Fluorescence ; Fetus/abnormalities
    Language Chinese
    Publishing date 2024-04-29
    Publishing country China
    Document type Journal Article ; Case Reports ; English Abstract
    ISSN 1003-9406
    ISSN 1003-9406
    DOI 10.3760/cma.j.cn511374-20230814-00064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Reading-Related Skills Associated With Acquisition of Chinese as a Second/Foreign Language: A Meta-Analysis.

    Chen, Xi / Zhao, Jingjing

    Frontiers in psychology

    2022  Volume 13, Page(s) 783964

    Abstract: Previous studies have found the effect of cognitive skills (e.g., phonological awareness, morphological awareness, orthographic awareness, and rapid automatized naming) on reading ability, but the role of different reading-related skills in acquisition ... ...

    Abstract Previous studies have found the effect of cognitive skills (e.g., phonological awareness, morphological awareness, orthographic awareness, and rapid automatized naming) on reading ability, but the role of different reading-related skills in acquisition of Chinese as a second/foreign language (CSL/CFL) remains unexplored. Prior meta-analyses on the relationship between cognitive skills and reading have been conducted primarily in native English-speaking or Mandarin-speaking children. The purpose of the present meta-analysis was to examine the relationship between Chinese reading-related skills and Chinese word reading of CSL/CFL learners. A search of English and Chinese databases yielded 42 effect sizes, comprising 1103 subjects met the criteria for meta-analysis and were included in the final meta-analysis. Results revealed a moderate relationship between phonological awareness (
    Language English
    Publishing date 2022-03-16
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.783964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Improved antioxidative and antibacterial activity of epigallocatechin gallate derivative complexed by zinc cations and chitosan.

    Zhao, Jingjing / Qian, Dou / Zhang, Luyang / Wang, Xiao / Zhang, Jianfeng

    RSC advances

    2024  Volume 14, Issue 15, Page(s) 10410–10415

    Abstract: Epigallocatechin gallate (EGCG) has attracted increasing attention thanks to its multi-bioactivities, and people are keen on improving the antioxidative and antibacterial performance of EGCG. Based on the favorable biofunctionality of ... ...

    Abstract Epigallocatechin gallate (EGCG) has attracted increasing attention thanks to its multi-bioactivities, and people are keen on improving the antioxidative and antibacterial performance of EGCG. Based on the favorable biofunctionality of Zn
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d4ra00255e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Strength Use and Well-Being at Work among Teachers: The Mediating Role of Basic Need Satisfaction.

    Wei, Cangpi / Su, Jiahe / Zhao, Jingjing / Ding, Ke / Kong, Feng

    Behavioral sciences (Basel, Switzerland)

    2024  Volume 14, Issue 2

    Abstract: Teachers' well-being at work is an important indicator of their mental health. Strengths use has been identified as a significant predictor of enhanced well-being at work. However, there is a scarcity of studies that have examined the connection between ... ...

    Abstract Teachers' well-being at work is an important indicator of their mental health. Strengths use has been identified as a significant predictor of enhanced well-being at work. However, there is a scarcity of studies that have examined the connection between teachers' strengths use and well-being at work; thus, its underlying psychological mechanism is unclear. Therefore, this study aimed to explore the association between teachers' strengths and well-being at work together with the mediating role of basic need satisfaction. A total of 374 university teachers completed a series of questionnaires on strengths use, basic need satisfaction, hedonic well-being, and eudaimonic well-being. The results showed that there were positive correlations between strength use and both types of well-being at work. Moreover, basic need satisfaction mediated the association between strength use and two types of well-being at work. The findings suggest that institutions should prioritize enhancing teachers' ability to utilize their strengths and foster an environment conducive to such practices, thereby improving their workplace well-being.
    Language English
    Publishing date 2024-01-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651997-5
    ISSN 2076-328X
    ISSN 2076-328X
    DOI 10.3390/bs14020095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Facial feedback manipulation influences the automatic detection of unexpected emotional body expressions.

    Liu, Jianyi / Liu, Yang / Jiang, Heng / Zhao, Jingjing / Ding, Xiaobin

    Neuropsychologia

    2024  Volume 195, Page(s) 108802

    Abstract: Unexpected or changing facial expressions are known to be able to engage more automatic processing than frequently occurring facial expressions, thereby inducing a neural differential wave response known as expression mismatch negativity (EMMN). Recent ... ...

    Abstract Unexpected or changing facial expressions are known to be able to engage more automatic processing than frequently occurring facial expressions, thereby inducing a neural differential wave response known as expression mismatch negativity (EMMN). Recent studies have shown that EMMN can be modulated by the observer's facial feedback (i.e., feedback from their own facial movements). A similar EMMN activity has been discovered for body expressions, but thus far only a few emotion types have been investigated. It is unknown whether the EMMNs evoked by body expressions can be influenced by facial feedback. To explore this question, we recorded EEG activity of 29 participants in the reverse oddball paradigm. Here two unexamined categories of body expressions were presented, happy and sad, placed in two paired stimulus sequences: in one the happy body was presented with a probability of 80% (standards) while the sad body was presented with a probability of 20% (deviants), and in the other the probabilities were reversed. The facial feedback was manipulated by different pen holding conditions (i.e., participants holding the pen with the teeth, lips, or nondominant hand). The nonparametric cluster permutation test revealed significant happy and sad body-related EMMN (bEMMN) activities. The happy-bEMMN were more negative than sad-bEMMN within the range of 100-150 ms. Additionally, the bEMMN amplitude of both emotions is modulated by the facial feedback conditions. These results expand the range of emotional types applicable to bEMMN and provide evidence for the validity of the facial feedback hypothesis across emotional carriers.
    MeSH term(s) Humans ; Electroencephalography ; Feedback ; Emotions/physiology ; Happiness ; Facial Expression ; Lip
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 207151-4
    ISSN 1873-3514 ; 0028-3932
    ISSN (online) 1873-3514
    ISSN 0028-3932
    DOI 10.1016/j.neuropsychologia.2024.108802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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