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  1. Book ; Online: Chapter 1 Salt, grain and the change of deities in early Ming western Yunnan

    Zhao, Min

    2019  

    Keywords Regional studies ; Social research & statistics ; Yunnan, Ming China
    Size 1 electronic resource (25 pages)
    Publisher Taylor and Francis
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021027740
    ISBN 9780367353360 ; 0367353369
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Analysis of volleyball players' force generation during jump spike from the perspective of electromyographic characteristics.

    Wang, Z I / Zhao, Min

    Acta of bioengineering and biomechanics

    2024  Volume 25, Issue 2, Page(s) 147–155

    Abstract: Purpose: The aim of this study was to investigate the force characteristics of novice athletes and professional athletes in completing a cross spike at position four from the perspective of electromyographic characteristics.: Methods: Ten novice and ... ...

    Abstract Purpose: The aim of this study was to investigate the force characteristics of novice athletes and professional athletes in completing a cross spike at position four from the perspective of electromyographic characteristics.
    Methods: Ten novice and ten professional athletes were selected as subjects. The electromyographic characteristics of the athletes were obtained by the Noraxon Ultium electromyography (EMG) and compared.
    Results: In the first stage, i.e., the takeoff stage, the activation level of the rectus abdominis and external abdominal obliques was significantly higher in the professional group (p<0.05). During the second stage, i.e., the stage of flying to hit the ball, the professional group had a higher integrated electromyography (iEMG) value in the trapezius. Moreover, it showed significantly higher muscle contribution from the rectus abdominis (5.59 ± 1.58%), external abdominal obliques (3.67 ± 1.21%), and trapezius (10.12 ± 2.61%) compared to the novice group (p<0.05). In the third stage, i.e., the stage of landing and buffering, p<0.05 in the comparison of the iEMG values of trapezius and gluteus maximus between the two groups. Moreover, the professional group exhibited higher muscle activation levels in all muscles except for the gastrocnemius, compared to the novice group (p<0.05).
    Conclusions: Professional athletes display superior muscle coordination and more effective muscle force generation in the trunk and lower limbs during the execution of the jump spike action.
    MeSH term(s) Humans ; Volleyball ; Muscle, Skeletal/physiology ; Electromyography ; Lower Extremity ; Biomechanical Phenomena
    Language English
    Publishing date 2024-02-05
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2559094-7
    ISSN 1509-409X
    ISSN 1509-409X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Rituximab combined with Bruton tyrosine kinase inhibitor to treat elderly diffuse large B-cell lymphoma patients: Two case reports.

    Zhang, Cang-Jian / Zhao, Min-Lei

    World journal of clinical cases

    2023  Volume 11, Issue 29, Page(s) 7170–7178

    Abstract: Background: Diffuse large B-cell lymphoma (DLBCL) is a common aggressive non-Hodgkin's lymphoma (NHL), accounting for 30%-40% of adult NHLs. This report aims to explore the efficacy and safety of rituximab combined with Bruton tyrosine kinase inhibitors ...

    Abstract Background: Diffuse large B-cell lymphoma (DLBCL) is a common aggressive non-Hodgkin's lymphoma (NHL), accounting for 30%-40% of adult NHLs. This report aims to explore the efficacy and safety of rituximab combined with Bruton tyrosine kinase inhibitors (BTKis) in the treatment of elderly patients with DLBCL.
    Case summary: The clinical data of two elderly patients with DLBCL who received rituximab combined with BTKi in our hospital were retrospectively analyzed, and the literature was reviewed. The patients were treated with chemotherapy using the R-miniCHOP regimen for two courses. Then, they received rituximab in combination with BTKi.
    Conclusion: The treatment experience in these cases demonstrates the potential efficacy of rituximab combined with BTKi to treat elderly DLBCL patients, thus providing a new treatment strategy.
    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i29.7170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: The heterogeneity of neuropsychiatric disorders.

    Wu, Zhao-Min / Yang, Bin-Rang

    Frontiers in psychiatry

    2023  Volume 13, Page(s) 1114164

    Language English
    Publishing date 2023-01-10
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2022.1114164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Causal role of immune cells in generalized anxiety disorder: Mendelian randomization study.

    Ma, Zhen / Zhao, Min / Zhao, Huanghong / Qu, Nan

    Frontiers in immunology

    2024  Volume 14, Page(s) 1338083

    Abstract: Background: Generalized anxiety disorder (GAD) is a prevalent emotional disorder that has received relatively little attention regarding its immunological basis. Recent years have seen the widespread use of high-density genetic markers such as SNPs or ... ...

    Abstract Background: Generalized anxiety disorder (GAD) is a prevalent emotional disorder that has received relatively little attention regarding its immunological basis. Recent years have seen the widespread use of high-density genetic markers such as SNPs or CNVs for genotyping, as well as the advancement of genome-wide association studies (GWAS) technologies, which have facilitated the understanding of immunological mechanisms underlying several major psychiatric disorders. Despite these advancements, the immunological basis of GAD remains poorly understood. In light of this, we aimed to explore the causal relationship between immune cells and the disease through a Mendelian randomization study.
    Methods: The summary information for GAD (Ncase=4,666, Ncontrol=337,577) was obtained from the FinnGen dataset. Summary statistics for the characterization of 731 immune cells, including morphological parameters (MP=32), median fluorescence intensity (MFI=389), absolute cells (AC=118), and relative cells (RC=192), were derived from the GWAS catalog. The study involved both forward MR analysis, with immune cell traits as the exposure and GAD as the outcome, and reverse MR analysis, with GAD as the exposure and immune cell traits as the outcome. We performed extensive sensitivity analyses to confirm the robustness, heterogeneity, and potential multi-biological effects of the study results. Also, to control for false positive results during multiple hypothesis testing, we adopted a false discovery rate (FDR) to control for statistical bias due to multiple comparisons.
    Results: After FDR correction, GAD had no statistically significant effect on immunophenotypes. Several phenotypes with unadjusted low P-values are worth mentioning, including decreased PB/PC levels on B cells(β=-0.289, 95%CI=0.044~0.194,
    Conclusion: The study has shown the close association between immune cells and GAD through genetic methods, thereby offering direction for future clinical research.
    MeSH term(s) Humans ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Anxiety Disorders ; Granulocytes ; B-Lymphocytes
    Language English
    Publishing date 2024-01-09
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1338083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The specialized sesquiterpenoids produced by the genus Elephantopus L.: Chemistry, biological activities and structure-activity relationship exploration.

    Rao, Qian-Ru / Rao, Jian-Bo / Zhao, Min

    Phytochemistry

    2024  Volume 221, Page(s) 114041

    Abstract: The genus Elephantopus L. is a valuable resource rich in sesquiterpenoids with structural diversity and various bioactivities, showing great potential for applications in medicinal field and biological industry. Up to now, over 129 sesquiterpenoids have ... ...

    Abstract The genus Elephantopus L. is a valuable resource rich in sesquiterpenoids with structural diversity and various bioactivities, showing great potential for applications in medicinal field and biological industry. Up to now, over 129 sesquiterpenoids have been isolated and identified from this plant genus, including 114 germacrane-type, 7 guaianolide-type, 5 eudesmane-type, 1 elemanolide-type, and 2 bis-sesquiterpenoids. These sesquiterpenoids were reported to show a diverse range of pharmacological properties, including cytotoxic, anti-tumor, anti-inflammatory, antimicrobial, and antiprotozoal. Consequently, some of them were identified as active scaffolds in the design and development of drugs. Considering that there is currently no overview available that covers the sesquiterpenoids and their biological activities in the Elephantopus genus, this article aims to comprehensively review the chemical structures, biosynthetic pathways, pharmacological properties, and structure-activity relationship of sesquiterpenoids found in the Elephantopus genus, which will establish a theoretical framework that can guide further research and exploration of sesquiterpenoids from Elephantopus plants as promising therapeutic agents.
    MeSH term(s) Molecular Structure ; Structure-Activity Relationship ; Asteraceae/chemistry ; Plant Extracts/chemistry ; Sesquiterpenes/chemistry ; Anti-Inflammatory Agents/pharmacology
    Chemical Substances Plant Extracts ; Sesquiterpenes ; Anti-Inflammatory Agents
    Language English
    Publishing date 2024-03-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 208884-8
    ISSN 1873-3700 ; 0031-9422
    ISSN (online) 1873-3700
    ISSN 0031-9422
    DOI 10.1016/j.phytochem.2024.114041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 1586: Show issues
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  7. Article ; Online: [Construction of mono/di-rhamnolipid ratios-manipulable strains and characterization of their corresponding surfactants' activity].

    Zhao, Min / Zheng, Yaqian / Yu, Haiying / Ma, Lüyan

    Sheng wu gong cheng xue bao = Chinese journal of biotechnology

    2024  Volume 40, Issue 3, Page(s) 786–798

    Abstract: Rhamnolipids (RLs) have emerged as one of the most promising classes of biosurfactants. The ratio of mono-RL to di-RL plays a significant role in determining its performance. Therefore, strains whose production of mono-RL and di-RL are manuplable, have ... ...

    Abstract Rhamnolipids (RLs) have emerged as one of the most promising classes of biosurfactants. The ratio of mono-RL to di-RL plays a significant role in determining its performance. Therefore, strains whose production of mono-RL and di-RL are manuplable, have advantage on applications in various scenarios. In this study, we developed a
    MeSH term(s) Arabinose ; Glycolipids/pharmacology ; Anti-Bacterial Agents/pharmacology ; Surface-Active Agents/pharmacology ; Pseudomonas aeruginosa/genetics
    Chemical Substances rhamnolipid ; Arabinose (B40ROO395Z) ; Glycolipids ; Anti-Bacterial Agents ; Surface-Active Agents
    Language Chinese
    Publishing date 2024-03-28
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1042206-7
    ISSN 1872-2075 ; 1042-749X
    ISSN (online) 1872-2075
    ISSN 1042-749X
    DOI 10.13345/j.cjb.230413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Loganin exerts neuroprotective effect by inhibiting neuronal pyroptosis in rat with cerebral haemorrhage.

    Wang, Yu / Zhao, Min / Li, Jing / Liu, Yue

    Clinical and experimental pharmacology & physiology

    2024  Volume 51, Issue 6, Page(s) e13858

    Abstract: Intracerebral haemorrhage (ICH) presents significant challenges in clinical management because of the high morbidity and mortality, necessitating novel therapeutic approaches. This study aimed to assess the neuroprotective effects of loganin in a rat ICH ...

    Abstract Intracerebral haemorrhage (ICH) presents significant challenges in clinical management because of the high morbidity and mortality, necessitating novel therapeutic approaches. This study aimed to assess the neuroprotective effects of loganin in a rat ICH model. Sprague-Dawley rats were used, subjected to a collagenase-induced ICH model, followed by loganin treatment at doses of 2.5, 5 and 10 mg/kg. Neurological functions were evaluated using the modified neurological severity score (mNSS) and a rotarod test. Results indicated a significant improvement in neurological functions in loganin-treated groups, evident from the mNSS and rotarod tests, suggesting dose-dependent neuroprotection. Loganin also effectively reduced the blood-brain barrier (BBB) permeability and cerebral oedema. Additionally, it mitigated cellular pyroptosis, as shown by terminal deoxynucleotidyl transferase dUTP nick-end labelling staining and western blot analysis, which indicated reduced levels of pyroptosis markers in treated rats. Furthermore, loganin's regulatory effects on the adenosine A2A receptor and myosin light chain kinase pathways were observed, potentially underpinning its protective mechanism against ICH. The study concludes that loganin exhibits significant neuroprotective properties in a rat ICH model, highlighting its potential as a novel therapeutic strategy. Despite promising results, the study needs further research to determine loganin's therapeutic potential in human ICH patients. This research paves the way for further exploration into loganin's clinical applications, potentially revolutionizing treatment strategies for patients suffering from intracerebral haemorrhage.
    MeSH term(s) Humans ; Rats ; Animals ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Rats, Sprague-Dawley ; Pyroptosis ; Cerebral Hemorrhage/complications ; Cerebral Hemorrhage/drug therapy ; Cerebral Hemorrhage/chemically induced ; Iridoids
    Chemical Substances Neuroprotective Agents ; loganin (H7WJ16Q93C) ; Iridoids
    Language English
    Publishing date 2024-04-16
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 189277-0
    ISSN 1440-1681 ; 0305-1870 ; 0143-9294
    ISSN (online) 1440-1681
    ISSN 0305-1870 ; 0143-9294
    DOI 10.1111/1440-1681.13858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 990: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article: Understanding and addressing the challenges of online gambling addiction in mainland China.

    Zhong, Gangliang / Du, Jiang / Zhao, Min

    General psychiatry

    2024  Volume 37, Issue 2, Page(s) e101477

    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2941976-1
    ISSN 2517-729X ; 2517-729X ; 2096-5923
    ISSN (online) 2517-729X
    ISSN 2517-729X ; 2096-5923
    DOI 10.1136/gpsych-2023-101477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Immunomodulation of Ethyl pyruvate on gestational diabetes mellitus in Mice; The impact on Th17/Treg balance.

    Zhao, Min / Bian, Xiuping / Meng, Li

    Reproductive biology

    2024  Volume 24, Issue 2, Page(s) 100861

    Abstract: Gestational diabetes mellitus (GDM) is recognized as one of the most common diseases among pregnant women and inflammatory responses can be a major reason for its induction and development. T helper 17 (Th17)/regulatory T cells (Tregs) imbalance ... ...

    Abstract Gestational diabetes mellitus (GDM) is recognized as one of the most common diseases among pregnant women and inflammatory responses can be a major reason for its induction and development. T helper 17 (Th17)/regulatory T cells (Tregs) imbalance resulting in the increased levels of pro-inflammatory and decreased levels of anti-inflammatory cytokines has been showed as major mechanisms involved in the pathogenesis of GDM. There are various treatment options, but none of them are completely therapeutic. Ethyl pyruvate (EP) is a stable derivate of pyruvate that showed anti-oxidant and anti-inflammatory properties in an in-vivo and in-vitro models. To examine the therapeutic efficacy of EP in GDM, mice were mated and EP (100 mg/kg) was administered intraperitoneally to C57BL/6 mice. EP-treated mice exhibited improved symptoms of GDM by decreased blood glucose levels and body-weight and increased insulin levels and insulin sensitivity. Furthermore, EP could significantly attenuate the impairments to offspring, including birth size and birth weight. The inflammatory responses were also decreased by EP through regulating the production of Th17-related cytokines, such as interleukin (IL)- 17 and IL-21. The levels of other inflammatory cytokines were also inhibited, including IL-1β, IL-6, and tumor necrosis factor (TNF)-α. In addition, it was found that EP increased the population of Tregs and Treg-related cytokines, IL-10 and transforming Growth Factor-β TGF-β, in GDM mice. In conclusion, EP could modulate GDM in mice and might be a potential therapeutic strategy candidate for the treatment of patients with GDM.
    Language English
    Publishing date 2024-04-24
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2189316-0
    ISSN 2300-732X ; 1642-431X
    ISSN (online) 2300-732X
    ISSN 1642-431X
    DOI 10.1016/j.repbio.2024.100861
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6095: Show issues Location:
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