LIVIVO - Search results -

Search results

Result 1 - 10 of total 12

Search options

Article ; Online: Updating cut-off values of severity scoring systems for community-acquired pneumonia to orchestrate more predictive accuracy.

Guo, Qi / Li, Hai-Yan / Song, Wei-Dong / Li, Ming / Chen, Xiao-Ke / Liu, Hui / Peng, Hong-Lin / Yu, Hai-Qiong / Liu, Nian / Li, Yan-Hong / Lü, Zhong-Dong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

Annals of medicine

2023 Volume 55, Issue 1, Page(s) 2202414

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Humans ; Aged ; Prospective Studies ; Retrospective Studies ; Pneumonia/diagnosis ; Hypotension ; ROC Curve ; Community-Acquired Infections/diagnosis ; Severity of Illness Index ; Prognosis
Language	English
Publishing date	2023-04-19
Publishing country	England
Document type	Journal Article
ZDB-ID	1004226-x
ISSN	1365-2060 ; 1651-2219 ; 0785-3890 ; 1743-1387
ISSN (online)	1365-2060 ; 1651-2219
ISSN	0785-3890 ; 1743-1387
DOI	10.1080/07853890.2023.2202414
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 680: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: qSOFA predicted pneumonia mortality better than minor criteria and worse than CURB-65 with robust elements and higher convergence.

Guo, Qi / Li, Hai-Yan / Song, Wei-Dong / Liu, Hui / Yu, Hai-Qiong / Li, Yan-Hong / Lü, Zhong-Dong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

The American journal of emergency medicine

2021 Volume 52, Page(s) 1–7

Abstract: Background: Limited data are available on the discriminatory capacity of quick sequential [sepsis-related] organ failure assessment (qSOFA) versus IDSA/ATS minor criteria for predicting mortality in patients with community-acquired pneumonia (CAP).: ... ...

Abstract	Background: Limited data are available on the discriminatory capacity of quick sequential [sepsis-related] organ failure assessment (qSOFA) versus IDSA/ATS minor criteria for predicting mortality in patients with community-acquired pneumonia (CAP). Methods: An observational prospective cohort study of 2116 patients with CAP was performed. Construct validity was determined using Cronbach α. Discrimination was assessed using the area under the receiver operating characteristic curve (AUROC) and net reclassification improvement (NRI). Results: Overall in-hospital mortality was 6.43%. Mortality was 25.96% for patients with a qSOFA score of 2 or higher versus 3.05% for those with a qSOFA score less than 2 (odds ratio for mortality 6.57, P < 0.0001), and 13.85% for patients with at least 3 minor criteria versus 2.03% for those with 2 or fewer minor criteria (odds ratio for mortality 2.27, P < 0.0001). qSOFA had a higher correlation with mortality than minor criteria, as well as higher internal consistency (Cronbach alpha 0.43 versus 0.14) and diagnostic values of individual elements (larger AUROCs and higher Youden's indices). qSOFA ≥2 was less sensitive but more specific for predicting mortality than ≥3 minor criteria (qSOFA sensitivity 59.6%, specificity 88.3% and positive likelihood ratio 5.11 versus ≥3 minor criteria sensitivity 80.1%, specificity 65.8% and positive likelihood ratio 2.34). The predictive validity of qSOFA was good for mortality (AUROC = 0.868), was statistically greater than minor criteria, was equal to pneumonia severity index, and was inferior compared with CURB-65 (AUROC, 0.824, 0.902, 0.919; NRI, 0.088, -0.068, -0.103; respectively). Conclusions: The qSOFA predicted mortality in CAP better than IDSA/ATS minor criteria and worse than CURB-65 with robust elements and higher convergence. qSOFA as a bedside prompt might be positioned as a proxy for minor criteria and increase the recognition and thus merit more appropriate management of CAP patients likely to fare poorly, which might have implications for more accurate clinical triage decisions.
MeSH term(s)	Adult ; Community-Acquired Infections/diagnosis ; Community-Acquired Infections/mortality ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Organ Dysfunction Scores ; Pneumonia/complications ; Pneumonia/diagnosis ; Pneumonia/mortality ; Predictive Value of Tests ; Prospective Studies ; Sepsis/diagnosis ; Sepsis/etiology ; Sepsis/mortality
Language	English
Publishing date	2021-11-24
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	605890-5
ISSN	1532-8171 ; 0735-6757
ISSN (online)	1532-8171
ISSN	0735-6757
DOI	10.1016/j.ajem.2021.11.029
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2005: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Cold-inducible RNA-binding protein might determine the severity and the presences of major/minor criteria for severe community-acquired pneumonia and best predicted mortality.

Guo, Qi / Song, Wei-Dong / Li, Hai-Yan / Li, Ming / Chen, Xiao-Ke / Liu, Hui / Peng, Hong-Lin / Yu, Hai-Qiong / Liu, Nian / Lü, Zhong-Dong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

Respiratory research

2020 Volume 21, Issue 1, Page(s) 192

Abstract: Background: Severity of community-acquired pneumonia (CAP) depends on microbial pathogenicity, load and virulence, and immune responses. The Infectious Disease Society of America and the American Thoracic Society (IDSA/ATS) minor criteria responsible ... ...

Abstract	Background: Severity of community-acquired pneumonia (CAP) depends on microbial pathogenicity, load and virulence, and immune responses. The Infectious Disease Society of America and the American Thoracic Society (IDSA/ATS) minor criteria responsible for clinical triage of patients with CAP are of unequal weight in predicting mortality. It is unclear whether the IDSA/ATS major/minor criteria might be strongly and positively associated with the immune responses. It is warranted to explore this intriguing hypothesis. Methods: A prospective cohort study of 404 CAP patients was performed. Cold-inducible RNA-binding protein (CIRP) levels were measured using a sandwich-based enzyme-linked immunosorbent assay. The receiver operating characteristic curves were created and the areas under the curves were calculated to illustrate and compare the accuracy of the indices. Results: Severe CAP patients meeting the major criteria had the highest plasma concentrations of CIRP. The more the number of most predictive minor criteria strongly associated to mortality, i.e. arterial oxygen pressure/fraction inspired oxygen ≤ 250 mmHg, confusion, and uremia, present, the higher the CIRP level. Interestingly, the patients with non-severe CAP meeting the most predictive minor criteria demonstrated unexpectedly higher CIRP level compared with the patients with severe CAP not fulfilling the criteria. Procalcitonin (PCT), interleukin-6 (IL-6), C-reactive protein (CRP), sequential organ failure assessment (SOFA) and pneumonia severity index (PSI) scores, and mortality confirmed similar intriguing patterns. CIRP was strongly linked to PCT, IL-6, CRP, minor criteria, SOFA and PSI scores, and mortality (increased odds ratio 3.433). The pattern of sensitivity, specificity, positive predictive value, and Youden's index of CIRP ≥ 3.50 ng/mL for predicting mortality was the optimal. The area under the receiver operating characteristic curve of CIRP was the highest among the indices. Conclusions: CIRP levels were strongly correlated with the IDSA/ATS major/minor criteria. CIRP might determine the severity and the presences of major/minor criteria and best predicted mortality, and a CIRP of ≥ 3.50 ng/mL might be more valuable cut-off value for severe CAP, suggesting that CIRP might be a novel and intriguing biomarker for pneumonia to monitor host response and predict mortality, which might have implications for more accurate clinical triage decisions.
MeSH term(s)	Aged ; Aged, 80 and over ; Biomarkers/blood ; Cohort Studies ; Community-Acquired Infections/blood ; Community-Acquired Infections/diagnosis ; Female ; Humans ; Male ; Middle Aged ; Mortality/trends ; Pneumonia/blood ; Pneumonia/diagnosis ; Pneumonia/mortality ; Prognosis ; Prospective Studies ; RNA-Binding Proteins/blood ; Severity of Illness Index
Chemical Substances	Biomarkers ; CIRBP protein, human ; RNA-Binding Proteins
Language	English
Publishing date	2020-07-20
Publishing country	England
Document type	Journal Article ; Multicenter Study
ZDB-ID	2041675-1
ISSN	1465-993X ; 1465-9921
ISSN (online)	1465-993X
ISSN	1465-9921
DOI	10.1186/s12931-020-01457-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Correction to: Scored minor criteria for severe community-acquired pneumonia predicted better.

Guo, Qi / Song, Wei-Dong / Li, Hai-Yan / Zhou, Yi-Ping / Li, Ming / Chen, Xiao-Ke / Liu, Hui / Peng, Hong-Lin / Yu, Hai-Qiong / Chen, Xia / Liu, Nian / Lü, Zhong-Dong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

Respiratory research

2019 Volume 20, Issue 1, Page(s) 147

Abstract: ...

Abstract	.
Language	English
Publishing date	2019-07-10
Publishing country	England
Document type	Published Erratum
ZDB-ID	2041675-1
ISSN	1465-993X ; 1465-9921
ISSN (online)	1465-993X
ISSN	1465-9921
DOI	10.1186/s12931-019-1122-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Scored minor criteria for severe community-acquired pneumonia predicted better.

Respiratory research

2019 Volume 20, Issue 1, Page(s) 22

Abstract: Background: Infectious Disease Society of America/American Thoracic Society (IDSA/ATS) minor criteria for severe community-acquired pneumonia (CAP) are of unequal weight in predicting mortality, but the major problem associated with IDSA/ATS minor ... ...

Abstract	Background: Infectious Disease Society of America/American Thoracic Society (IDSA/ATS) minor criteria for severe community-acquired pneumonia (CAP) are of unequal weight in predicting mortality, but the major problem associated with IDSA/ATS minor criteria might be a lack of consideration of weight in prediction in clinical practice. Would awarding different points to the presences of the minor criteria improve the accuracy of the scoring system? It is warranted to explore this intriguing hypothesis. Methods: A total of 1230 CAP patients were recruited to a retrospective cohort study. This was tested against a prospective two-center cohort of 1749 adults with CAP. 2 points were assigned for the presence of PaO Results: The mortality rates, and sequential organ failure assessment (SOFA) and pneumonia severity index (PSI) scores increased significantly with the numbers of IDSA/ATS minor criteria present and minor criteria scores. The correlations of the minor criteria scores with the mortality rates were higher than those of the numbers of IDSA/ATS minor criteria present. As were the correlations of the minor criteria scores with SOFA and PSI scores, compared with the numbers of IDSA/ATS minor criteria present. The pattern of sensitivity, specificity, positive predictive value, and Youden's index of scored minor criteria of ≥2 scores or the presence of 2 or more IDSA/ATS minor criteria for prediction of mortality was the best in the retrospective cohort, and the former was better than the latter. The validation cohort confirmed a similar pattern. The area under the receiver operating characteristic curve of scored minor criteria was higher than that of IDSA/ATS minor criteria in the retrospective cohort, implying higher accuracy of scored version for predicting mortality. The validation cohort confirmed a similar paradigm. Conclusions: Scored minor criteria orchestrated improvements in predicting mortality and severity in patients with CAP, and scored minor criteria of ≥2 scores or the presence of 2 or more IDSA/ATS minor criteria might be more valuable cut-off value for severe CAP, which might have implications for more accurate clinical triage decisions.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Algorithms ; Cohort Studies ; Community-Acquired Infections/diagnosis ; Community-Acquired Infections/mortality ; Confusion/etiology ; Confusion/psychology ; Female ; Humans ; Male ; Middle Aged ; Multiple Organ Failure/etiology ; Multiple Organ Failure/mortality ; Oxygen/blood ; Pneumonia/diagnosis ; Pneumonia/mortality ; Predictive Value of Tests ; Reference Standards ; Retrospective Studies ; Uremia/etiology ; Young Adult
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2019-01-31
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Validation Studies
ZDB-ID	2041675-1
ISSN	1465-993X ; 1465-9921
ISSN (online)	1465-993X
ISSN	1465-9921
DOI	10.1186/s12931-019-0991-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Priority for Treatment and Intensive Care of Patients With Non-Severe Community-Acquired Pneumonia.

Li, Hai-Yan / Guo, Qi / Song, Wei-Dong / Zhou, Yi-Ping / Li, Ming / Chen, Xiao-Ke / Liu, Hui / Peng, Hong-Lin / Yu, Hai-Qiong / Chen, Xia / Liu, Nian / Lü, Zhong-Dong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

The American journal of the medical sciences

2018 Volume 356, Issue 4, Page(s) 329–334

Abstract: Background: The Infectious Disease Society of America/the American Thoracic Society (IDSA/ATS) minor criteria for severe community-acquired pneumonia (CAP) are of unequal weight in predicting mortality. It is unclear whether the patients with non-severe ...

Abstract	Background: The Infectious Disease Society of America/the American Thoracic Society (IDSA/ATS) minor criteria for severe community-acquired pneumonia (CAP) are of unequal weight in predicting mortality. It is unclear whether the patients with non-severe CAP meeting the minor criteria most strongly associated to mortality should have the priority for treatment and intensive care. It is warranted to explore this intriguing hypothesis. Methods: A retrospective cohort study of 1230 patients with CAP was performed. This was tested against a prospective 2-center cohort of 1749 adults with CAP. Results: The patients with CAP fulfilling the predictive findings most strongly associated to mortality, i.e. PaO2/FiO2 ≤ 250 mm Hg, confusion, and uremia, showed higher mortality rates than those not fulfilling the predictive findings in subgroup analyses of the retrospective cohort. The more the number of predictive findings present, the higher the mortality rates. The prospective cohort confirmed a similar pattern. Interestingly, the patients with non-severe CAP meeting the predictive findings demonstrated unexpectedly higher mortality rates compared with the patients with severe CAP not meeting the predictive findings in the prospective cohort (P = 0.003), although there only existed death of an uptrend in the retrospective cohort. Two similar and intriguing paradigms about sequential organ failure assessment (SOFA) scores and pneumonia severity index (PSI) scores were confirmed in the 2 cohorts. Conclusions: The patients with non-severe CAP fulfilling the predictive findings most strongly associated to mortality demonstrated higher SOFA and PSI scores and mortality rates, and might have the priority for treatment and intensive care.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; China ; Community-Acquired Infections/etiology ; Community-Acquired Infections/mortality ; Community-Acquired Infections/therapy ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Organ Dysfunction Scores ; Pneumonia/etiology ; Pneumonia/mortality ; Pneumonia/therapy ; Prospective Studies ; Retrospective Studies ; Severity of Illness Index ; Young Adult
Language	English
Publishing date	2018-08-07
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	82078-7
ISSN	1538-2990 ; 0002-9629
ISSN (online)	1538-2990
ISSN	0002-9629
DOI	10.1016/j.amjms.2018.08.002
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.2/10: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Modified IDSA/ATS Minor Criteria for Severe Community-Acquired Pneumonia Best Predicted Mortality.

Medicine

2015 Volume 94, Issue 36, Page(s) e1474

Abstract: It is not clear whether the IDSA/ATS minor criteria for severe community-acquired pneumonia (CAP) could be simplified or even be modified to orchestrate improvements in predicting mortality.A retrospective cohort study of 1230 CAP patients was performed ... ...

Abstract	It is not clear whether the IDSA/ATS minor criteria for severe community-acquired pneumonia (CAP) could be simplified or even be modified to orchestrate improvements in predicting mortality.A retrospective cohort study of 1230 CAP patients was performed to simplify and to modify the scoring system by excluding 4 noncontributory or infrequent variables (leukopenia, hypothermia, hypotension, and thrombocytopenia) and by excluding these variables and then adding age ≥65 years, respectively. The simplification and modification were tested against a prospective 2-center validation cohort of 1409 adults with CAP.The increasing numbers of IDSA/ATS, simplified, and modified minor criteria present in the retrospective cohort were positively associated with the mortality, showing significant increased odds ratios for mortality of 2.711, 4.095, and 3.755, respectively. The validation cohort confirmed a similar pattern. The sensitivity, specificity, positive predictive value, and Youden index of modified minor criteria for mortality prediction were the best pattern in the retrospective cohort. High values of corresponding indices were confirmed in the validation cohort. The highest accuracy of the modified version for predicting mortality in the retrospective cohort was illustrated by the highest area under the receiver operating characteristic curve of 0.925 (descending order: modified, simplified, and IDSA/ATS minor criteria). The validation cohort confirmed a similar paradigm.The IDSA/ATS minor criteria could be simplified to 5 variables and then be modified to orchestrate improvements in predicting mortality in CAP patients. The modified version best predicted mortality. These were more suitable for clinic and emergency department.
MeSH term(s)	Adult ; Age Factors ; Aged ; China/epidemiology ; Cohort Studies ; Community-Acquired Infections/blood ; Community-Acquired Infections/diagnosis ; Community-Acquired Infections/mortality ; Community-Acquired Infections/physiopathology ; Female ; Humans ; Hypotension/etiology ; Hypothermia/etiology ; Lung/diagnostic imaging ; Male ; Patient Admission/standards ; Pneumonia/blood ; Pneumonia/diagnosis ; Pneumonia/mortality ; Pneumonia/physiopathology ; Predictive Value of Tests ; Prognosis ; Radiography ; Research Design ; Respiratory Rate ; Retrospective Studies ; Severity of Illness Index ; Thrombocytopenia/etiology
Language	English
Publishing date	2015-07-02
Publishing country	United States
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000001474
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.171: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: CUR-65 Score for Community-Acquired Pneumonia Predicted Mortality Better Than CURB-65 Score in Low-Mortality Rate Settings.

Li, Hai-yan / Guo, Qi / Song, Wei-dong / Zhou, Yi-ping / Li, Ming / Chen, Xiao-ke / Liu, Hui / Peng, Hong-lin / Yu, Hai-qiong / Chen, Xia / Liu, Nian / Lü, Zhong-dong / Liang, Li-hua / Zhao, Qing-zhou / Jiang, Mei

The American journal of the medical sciences

2015 Volume 350, Issue 3, Page(s) 186–190

Abstract: Background: It is not clear whether low-blood pressure criterion could be removed from CURB-65 (confusion, urea >7 mmol/L, respiratory rate ≥30/min, low blood pressure and age ≥65 years) score to orchestrate an improvement in identifying patients with ... ...

Abstract	Background: It is not clear whether low-blood pressure criterion could be removed from CURB-65 (confusion, urea >7 mmol/L, respiratory rate ≥30/min, low blood pressure and age ≥65 years) score to orchestrate an improvement in identifying patients with community-acquired pneumonia (CAP) in low-mortality rate settings. Methods: A retrospective cohort study of 1,230 CAP patients was performed to simplify the CURB-65 scoring system by excluding low-blood pressure variable. The simplification was validated in a prospective 2-center cohort of 1,409 adults with CAP. Results: The hospital mortalities were 1.3% and 3.8% in the retrospective and prospective cohorts, respectively. The mortality rates in the 2 cohorts increased directly with the increasing scores, showing significant increased odds ratios for mortality. The pattern of sensitivity, specificity, positive predictive value and Youden's index of a CUR-65 (Confusion, Urea >7 mmol/L, Respiratory rate ≥30/min and age ≥65 years) score of ≥2 for prediction of mortality was better than that of a CURB-65 score of ≥3 in the retrospective cohort. Higher values of corresponding indices were confirmed in the validation cohort. The higher accuracy of CUR-65 score for predicting mortality was illustrated by the area under the receiver operating characteristic curve of 0.937, compared with 0.915 for CURB-65 score in the retrospective cohort (P = 0.0073). The validation cohort confirmed a similar paradigm (0.953 versus 0.907, P = 0.0002). Conclusions: CURB-65 score could be simplified by removing low blood pressure to orchestrate an improvement in predicting mortality in CAP patients who have a low risk of death. A CUR-65 score of ≥2 might be a more valuable cutoff value for severe CAP.
MeSH term(s)	Cohort Studies ; Community-Acquired Infections/diagnosis ; Community-Acquired Infections/mortality ; Confusion/diagnosis ; Confusion/epidemiology ; Female ; Hospital Mortality/trends ; Humans ; Hypotension/diagnosis ; Hypotension/epidemiology ; Male ; Middle Aged ; Pneumonia, Bacterial/diagnosis ; Pneumonia, Bacterial/mortality ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; ROC Curve ; Respiratory Rate ; Retrospective Studies ; Sensitivity and Specificity ; Severity of Illness Index ; Urea/blood ; Uremia/diagnosis ; Uremia/epidemiology
Chemical Substances	Urea (8W8T17847W)
Language	English
Publishing date	2015-09
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	82078-7
ISSN	1538-2990 ; 0002-9629
ISSN (online)	1538-2990
ISSN	0002-9629
DOI	10.1097/MAJ.0000000000000545
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.2/10: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Mortality among severe community-acquired pneumonia patients depends on combinations of 2007 IDSA/ATS minor criteria.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2015 Volume 38, Page(s) 141–145

Abstract: Objectives: The individual 2007 Infectious Disease Society of America (IDSA)/American Thoracic Society (ATS) minor criteria for severe community-acquired pneumonia (CAP) are of unequal weight in predicting mortality. It is not clear whether the ... ...

Abstract	Objectives: The individual 2007 Infectious Disease Society of America (IDSA)/American Thoracic Society (ATS) minor criteria for severe community-acquired pneumonia (CAP) are of unequal weight in predicting mortality. It is not clear whether the combinations of predictive findings might imply diverse severities or different mortalities. Methods: A prospective two centre cohort study was performed of 385 severe CAP patients fulfilling three or more IDSA/ATS minor criteria amongst 1430 patients. Results: Hospital mortality rose sharply from 5.7%, 9.9%, and 16.5%, respectively, for patients with none of three predictive findings most strongly associated to mortality (PaO2/FiO2 ≤ 250mm Hg, confusion and uraemia), one of those, and two of those to 38.6% for patients with all those (p<0.001). The number of three predictive findings present had a significantly increased odds ratio for mortality of 2.796 (p<0.001), and had the degree of positive association with sequential organ failure assessment scores at 72hours, incurring significantly longer hospital stay and higher costs. Conclusions: Different combinations of 2007 IDSA/ATS minor criteria for severe CAP were associated to diverse severities and different mortalities. The combination of PaO2/FiO2 ≤ 250mm Hg, confusion and uraemia predicted more severity and higher mortality compared with others.
MeSH term(s)	Aged ; Cohort Studies ; Community-Acquired Infections/mortality ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Pneumonia/mortality ; Prospective Studies ; Severity of Illness Index
Language	English
Publishing date	2015-09
Publishing country	Canada
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2015.07.026
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4516: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Associations of radiological features in Mycoplasma pneumoniae pneumonia.

Guo, Qi / Li, Hai-Yan / Zhou, Yi-Ping / Li, Ming / Chen, Xiao-Ke / Peng, Hong-Lin / Yu, Hai-Qiong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

Archives of medical science : AMS

2013 Volume 10, Issue 4, Page(s) 725–732

Abstract: Introduction: The associations of radiological features with clinical and laboratory findings in Mycoplasma pneumoniae infection are poorly understood. The purpose of this study was to assess the associations.: Material and methods: A retrospective ... ...

Abstract	Introduction: The associations of radiological features with clinical and laboratory findings in Mycoplasma pneumoniae infection are poorly understood. The purpose of this study was to assess the associations. Material and methods: A retrospective cohort study of 1230 patients with community-acquired pneumonia was carried out between January 2005 and December 2009. The diagnosis of M. pneumoniae infection was made using the indirect microparticle agglutinin assay and enzyme-linked immunosorbent assay. Results: Females were more susceptible to M. pneumoniae infection. Ground-glass opacification on radiographs was positively associated with M. pneumoniae-IgM titres (rank correlation coefficient (r s) = 0.141, p = 0.006). The left upper lobe was more susceptible to infection with M. pneumoniae compared with other pathogens. More increases in the risk of multilobar opacities were found among older or male patients with M. pneumoniae pneumonia (odds ratio, 1.065, 3.279; 95% confidence interval, 1.041-1.089, 1.812-5.934; p < 0.001, p < 0.001; respectively). Patients with M. pneumoniae pneumonia showing multilobar opacities or consolidation had a significantly longer hospital length of stay (r s = 0.111, r s = 0.275; p = 0.033, p < 0.001; respectively), incurring significantly higher costs (r s = 0.119, r s = 0.200; p = 0.022, p < 0.001; respectively). Conclusions: Our study highlighted female susceptibility to M. pneumoniae pneumonia and the association of ground-glass opacification with higher M. pneumoniae-IgM titres. The left upper lobe might be more susceptible to M. pneumoniae infection. Older or male patients with M. pneumoniae pneumonia were more likely to show multilobar opacities. Multilobar opacities and consolidation were positively associated with hospital length of stay and costs.
Language	English
Publishing date	2013-03-06
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2203781-0
ISSN	1734-1922
ISSN	1734-1922
DOI	10.5114/aoms.2014.44863
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito