LIVIVO - Search results -

Search results

Result 1 - 10 of total 18

Search options

Article: Potential habitat areas and priority protected areas of

Zhang, Fen-Guo / Zhang, Sanqing / Wu, Kefan / Zhao, Ruxia / Zhao, Guanghua / Wang, Yongji

2024 Volume 15, Page(s) 1365264

Abstract: Introduction: Tilia amurensis Rupr: Methods: In this study, the R language was used to evaluate 358 distribution records and 38 environment variables. The MaxEnt model was used to predict the potential distribution areas of : Results: The results ... ...

Abstract	Introduction: Tilia amurensis Rupr Methods: In this study, the R language was used to evaluate 358 distribution records and 38 environment variables. The MaxEnt model was used to predict the potential distribution areas of Results: The results showed that Bio18, Slope, Elev, Bio1, Bio9 and Bio2 were the dominant environmental factors affecting the distribution of Discussion: The total suitable area of
Language	English
Publishing date	2024-03-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2024.1365264
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Prediction of potential distribution areas and priority protected areas of

Wang, Yongji / Zhao, Ruxia / Zhou, Xueyong / Zhang, Xiaolong / Zhao, Guanghua / Zhang, Fenguo

Frontiers in plant science

2023 Volume 14, Page(s) 1200796

Abstract: Agastache ... ...

Abstract	Agastache rugosa
Language	English
Publishing date	2023-07-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2023.1200796
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: [Degradation of Ciprofloxacin by CuNiFe LDHs/BiO

Dang, Pu / Zhao, Ya-Juan / Xie, Hui-Dong / Wang, Kang-Kang / Zhao, Ru-Xia

Huan jing ke xue= Huanjing kexue

2023 Volume 44, Issue 10, Page(s) 5587–5598

Abstract: Herein, a CuNiFe LDHs/ ... ...

Abstract	Herein, a CuNiFe LDHs/BiO
Language	Chinese
Publishing date	2023-08-30
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	0250-3301
ISSN	0250-3301
DOI	10.13227/j.hjkx.202210135
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Prediction of potential suitable habitats in the 21st century and GAP analysis of priority conservation areas of

Wang, Yongji / Wu, Kefan / Zhao, Ruxia / Xie, Liyuan / Li, Yifan / Zhao, Guanghua / Zhang, Fen-Guo

Frontiers in plant science

2024 Volume 15, Page(s) 1304121

Abstract: Chionanthus retusus (C. retusus) ...

Abstract	Chionanthus retusus (C. retusus)
Language	English
Publishing date	2024-02-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2024.1304121
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Adenovirus-mediated effects of Wnt and Notch signalling pathways on hair cell regeneration in mice

Weng, Menglu / Zhao, Ruxia / Niu, Qiaohua / Zeng, Yizheng / Wang, Xi / Gao, Xue / Han, Zhongming / Bing, Jie / Xi, Chao / Liu, Jin / Xu, Jincao / Yang, Siyuan / Zeng, Shaoju

Biochemical and Biophysical Research Communications. 2023 May, v. 658 p.44-54

2023

Abstract: Some genes are delivered to cochleae by adenoviruses to restore partial hearing function. This provides promising prospects for gene therapies for hearing loss from hair cell damage. To study the adenovirus (AD)-mediated effect of the Wnt and Notch ... ...

Abstract	Some genes are delivered to cochleae by adenoviruses to restore partial hearing function. This provides promising prospects for gene therapies for hearing loss from hair cell damage. To study the adenovirus (AD)-mediated effect of the Wnt and Notch signalling pathways on hair cell regeneration in the mouse cochlea, we constructed a β-catenin-adenovirus (β-catenin-AD) to increase the activity of the Wnt signalling pathway and a NICD (intracellular domain of Notch1)-RNAi-adenovirus to decrease the activity of the Notch signalling pathway (NICD-RNAi-AD). Our study indicated that approximately 40% of supporting cells in the cochleae damaged by gentamicin were infected with the adenoviruses. Following the β-catenin-AD-mediated increase in Wnt signalling pathway activity, mitotic regeneration was increased, while direct transdifferentiation was increased after the NICD-RNAi-AD-mediated decrease in Notch signalling pathway activity. The expected synergistic interaction on hair cell regeneration was not obtained after coinfection of β-catenin-AD and NICD-RNAi-AD into the damaged cochleae, which might be due to the low cotransfection efficiency to supporting cells. Our study indicated that it may be possible to develop AD mediated gene therapies for hearing loss that act by regulating the Wnt and Notch signalling pathways.
Keywords	Adenoviridae ; genes ; gentamicin ; mice ; mitosis ; mixed infection ; research ; synergism ; Adenoviruses ; Hair cells ; Signalling pathways ; Regeneration ; Gentamicin damage
Language	English
Dates of publication	2023-05
Size	p. 44-54.
Publishing place	Elsevier Inc.
Document type	Article ; Online
ZDB-ID	205723-2
ISSN	0006-291X ; 0006-291X
ISSN (online)	0006-291X
ISSN	0006-291X
DOI	10.1016/j.bbrc.2023.03.056
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 71/706: Show issues
Z 3.8: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: The effect of combined supplementation with vitamin D and omega-3 fatty acids on blood glucose and blood lipid levels in patients with gestational diabetes.

Huang, Shuzhen / Fu, Jifen / Zhao, Ruxia / Wang, Bin / Zhang, Meiling / Li, Lijuan / Shi, Chun

Annals of palliative medicine

2021 Volume 10, Issue 5, Page(s) 5652–5658

Abstract: Background: To investigate the effects of vitamin D and omega-3 fatty acids on glucose and blood lipid metabolism in gestational diabetes (GDM) women.: Methods: A total of 150 patients with GDM aged 18-40 who were admitted to our hospital from May ... ...

Abstract	Background: To investigate the effects of vitamin D and omega-3 fatty acids on glucose and blood lipid metabolism in gestational diabetes (GDM) women. Methods: A total of 150 patients with GDM aged 18-40 who were admitted to our hospital from May 2019 to December 2020 were enrolled in this study. The subjects were divided into test and control groups according to whether they took vitamin D and omega-3 fatty acids. The test group took 40,000 IU of vitamin D and 8,000 mg of omega-3 fatty acids twice a day. Comparative analysis of the changes in blood glucose and blood lipid levels of the two groups of patients was performed after 6 weeks. The t-test was used to compare the differences between groups, and the chi-square test was used to assess percentage differences. Repeated measures variance was used to analyze the effects of vitamin D and omega-3 fatty acids on insulin metabolism markers and blood lipid profiles. Results: After adjusting for baseline age and weight, it was found that the fasting blood glucose (FBG), fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), triglycerides (TGs), total cholesterol, low-density lipoprotein (LDL), and very-low-density lipoprotein (VLDL) in the test group were decreased by 0.3±0.2 mmol/L, 1.0±0.6 uIU/mL, 0.2±0.1, 0.3±0.1 mmol/L, 0.5±0.2 mmol/L, 1.1±0.4 mmol/L, and 0.03±0.01 mmol/L, respectively, while homeostasis model assessment of beta cell (HOMA-β) was increased by 0.4±0.1. Compared to the placebo group, the test group's FBG, insulin, HOMA-IR, TGs, total cholesterol, LDL, and VLDL were all significantly decreased, and HOMA-β was markedly improved. However, no notable statistical difference was observed in the change of high-density lipoprotein (HDL) (P>0.05). Conclusions: Combined supplementation with vitamin D and omega-3 fatty acids for 6 weeks in patients with GDM can effectively reduce blood sugar and blood lipids, improve HOMA-β and insulin resistance, and ultimately effectively improve the glucose and lipid metabolism of patients.
MeSH term(s)	Blood Glucose ; Diabetes, Gestational/drug therapy ; Dietary Supplements ; Fatty Acids, Omega-3/therapeutic use ; Female ; Humans ; Lipids ; Pregnancy ; Vitamin D
Chemical Substances	Blood Glucose ; Fatty Acids, Omega-3 ; Lipids ; Vitamin D (1406-16-2)
Language	English
Publishing date	2021-06-09
Publishing country	China
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2828544-X
ISSN	2224-5839 ; 2224-5839
ISSN (online)	2224-5839
ISSN	2224-5839
DOI	10.21037/apm-21-1018
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Micro‐ and nano‐emulsions based on soluble soy polysaccharide and octenyl succinic anhydride modified soluble soy polysaccharide

Qi, Jun‐Ru / Zhang, Dai‐Yu / Zhao, Ru‐Xia / Liao, Jin‐Song / Cao, Yong / Xiao, Jie

International journal of food science & technology. 2021 June, v. 56, no. 6

2021

Abstract: In this study, emulsion stabilised by soybean soluble polysaccharide (SSPS) and octenyl succinic anhydride modified SSPS (OSA‐SSPS) with high molecular weight (HMW) at concentrations (2%, 3%, 4%, 5%, 6%) was prepared. The droplet size of emulsion ... ...

Abstract	In this study, emulsion stabilised by soybean soluble polysaccharide (SSPS) and octenyl succinic anhydride modified SSPS (OSA‐SSPS) with high molecular weight (HMW) at concentrations (2%, 3%, 4%, 5%, 6%) was prepared. The droplet size of emulsion stabilised by OSA‐SSPS (HMW) was between 150 and 300 nm with a single distribution peak and increased by 0.1 μm after 4 weeks; that of emulsion stabilised by SSPS was between 1 and 5 μm with two distribution peaks and increased by more than 2 μm after 4 weeks. The viscosity of emulsion with OSA‐SSPS (HMW) was larger than that with SSPS, and the absolute value of zeta potential of microemulsion with SSPS was lower than 43 mV while that of nanoemulsion with OSA‐SSPS (HMW) was higher than 46 mV. The stability of nanoemulsion with OSA‐SSPS (HMW) slightly varied with the increase of storage time and concentration, which provided theoretical guidance for the application of OSA‐SSPS in nanoemulsion.
Keywords	anhydrides ; droplet size ; food science ; molecular weight ; nanoemulsions ; polysaccharides ; soybeans ; storage time ; viscosity ; zeta potential
Language	English
Dates of publication	2021-06
Size	p. 3034-3043.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	NAL-AP-2-clean ; JOURNAL ARTICLE
ZDB-ID	883561-5
ISSN	0950-5423
ISSN	0950-5423
DOI	10.1111/ijfs.14947
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 2121: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Adenovirus-mediated effects of Wnt and Notch signalling pathways on hair cell regeneration in mice.

Weng, Menglu / Zhao, Ruxia / Niu, Qiaohua / Zeng, Yizheng / Wang, Xi / Gao, Xue / Han, Zhongming / Bing, Jie / Xi, Chao / Liu, Jin / Xu, Jincao / Yang, Siyuan / Zeng, Shaoju

Biochemical and biophysical research communications

2023 Volume 658, Page(s) 44–54

Abstract	Some genes are delivered to cochleae by adenoviruses to restore partial hearing function. This provides promising prospects for gene therapies for hearing loss from hair cell damage. To study the adenovirus (AD)-mediated effect of the Wnt and Notch signalling pathways on hair cell regeneration in the mouse cochlea, we constructed a β-catenin-adenovirus (β-catenin-AD) to increase the activity of the Wnt signalling pathway and a NICD (intracellular domain of Notch1)-RNAi-adenovirus to decrease the activity of the Notch signalling pathway (NICD-RNAi-AD). Our study indicated that approximately 40% of supporting cells in the cochleae damaged by gentamicin were infected with the adenoviruses. Following the β-catenin-AD-mediated increase in Wnt signalling pathway activity, mitotic regeneration was increased, while direct transdifferentiation was increased after the NICD-RNAi-AD-mediated decrease in Notch signalling pathway activity. The expected synergistic interaction on hair cell regeneration was not obtained after coinfection of β-catenin-AD and NICD-RNAi-AD into the damaged cochleae, which might be due to the low cotransfection efficiency to supporting cells. Our study indicated that it may be possible to develop AD mediated gene therapies for hearing loss that act by regulating the Wnt and Notch signalling pathways.
MeSH term(s)	Animals ; Mice ; beta Catenin/genetics ; beta Catenin/metabolism ; Adenoviridae/genetics ; Adenoviridae/metabolism ; Receptors, Notch/genetics ; Receptors, Notch/metabolism ; Wnt Signaling Pathway/physiology ; Hearing Loss
Chemical Substances	beta Catenin ; Receptors, Notch
Language	English
Publishing date	2023-03-31
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205723-2
ISSN	1090-2104 ; 0006-291X ; 0006-291X
ISSN (online)	1090-2104 ; 0006-291X
ISSN	0006-291X
DOI	10.1016/j.bbrc.2023.03.056
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 116: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Calcineurin suppresses rat H9c2 cardiomyocyteprotective autophagy under chronic intermittent hypoxia by downregulating the AMPK pathway.

Ke, Changjiang / Huang, Yongjun / Mao, Zhenyu / Ke, Zhenghua / Wang, Zeng / Li, Ruyou / Long, Shenghua / Guo, Yuping / Wang, Fei / Qian, Meng / Zhao, Ruxia / Zheng, Juan / Xie, Sheng

Experimental cell research

2023 Volume 433, Issue 2, Page(s) 113850

Abstract: Calcineurin plays a key role in cardiovascular pathogenesis by exerting pro-apoptotic effects in cardiomyocytes. However, whether calcineurin can regulate cardiomyocyte autophagy under conditions of chronic intermittent hypoxia (CIH) remains unclear. ... ...

Abstract	Calcineurin plays a key role in cardiovascular pathogenesis by exerting pro-apoptotic effects in cardiomyocytes. However, whether calcineurin can regulate cardiomyocyte autophagy under conditions of chronic intermittent hypoxia (CIH) remains unclear. Here, we showed that CIH induced calcineurin activity in H9c2 cells, which attenuated adenosine monophosphate-activated protein kinase (AMPK) signaling and inhibited autophagy. In H9c2 cells, autophagy levels, LC3 expression, and AMPK phosphorylation were significantly elevated under conditions of CIH within 3 days. However, after 5 days of CIH, these effects were reversed and calcineurin activity and apoptosis were significantly increased. The calcineurin inhibitor 17-Allyl-1,14-dihydroxy-12-[2-(4-hydroxy-3-methoxycyclohexyl) -1-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo- [22.3.1.04,9]octacos-18- ene-2,3,10,16-tetrone (FK506) restored AMPK activation and LC3 expression and attenuated CIH-induced H9c2 cell apoptosis. In contrast, calcineurin overexpression significantly attenuated the increase in LC3 expression and enhanced H9c2 cell apoptosis under conditions of CIH. Calcineurin inhibition failed to induce autophagy or alleviate apoptosis in H9c2 cells expressing a kinase-dead K45R AMPK mutant. Autophagy inhibition abrogated the protective effects of FK506-mediated calcineurin inhibition. These results indicate that calcineurin suppresses adaptive autophagy during CIH by downregulating AMPK activation. Our findings reveal the underlying mechanism of calcineurin and autophagy regulation during H9c2 cell survival under conditions of CIH and may provide a new strategy for preventing CIH-induced cardiomyocyte damage.
MeSH term(s)	Animals ; Rats ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Apoptosis ; Autophagy ; Calcineurin/metabolism ; Hypoxia ; Myocytes, Cardiac/metabolism ; Tacrolimus/pharmacology
Chemical Substances	AMP-Activated Protein Kinases (EC 2.7.11.31) ; Calcineurin (EC 3.1.3.16) ; Tacrolimus (WM0HAQ4WNM)
Language	English
Publishing date	2023-11-04
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1493-x
ISSN	1090-2422 ; 0014-4827
ISSN (online)	1090-2422
ISSN	0014-4827
DOI	10.1016/j.yexcr.2023.113850
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 563: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Obesity is associated with poor outcomes of corticosteroid treatment in patients with primary immune thrombocytopenia.

Zhang, Xiaoyu / Liu, Qiang / Liu, Anli / Leng, Shaoqiu / Wang, Xiaolin / Zhao, Ruxia / Sheng, Zi / Feng, Qi / Yang, Xiaorong / Wang, Shuwen / Hou, Ming / Peng, Jun / Feng, Gege

British journal of haematology

2023 Volume 203, Issue 2, Page(s) 295–303

Abstract: Emerging evidence has demonstrated that obesity impacts multiple immune-related diseases. It remains unclear whether and how obesity alters treatment outcomes in patients with primary immune thrombocytopenia (ITP). Thus, we retrospectively investigated ... ...

Abstract	Emerging evidence has demonstrated that obesity impacts multiple immune-related diseases. It remains unclear whether and how obesity alters treatment outcomes in patients with primary immune thrombocytopenia (ITP). Thus, we retrospectively investigated 214 treatment-naïve patients who received standard high-dose dexamethasone therapy in Qilu Hospital. Patients with obesity showed significantly lower overall initial response (underweight vs. normal vs. overweight vs. obese: 85.7% vs. 85.2% vs. 72.0% vs. 52.3%, p = 0.001) and initial complete response ([CR], 71.4% vs. 70.4% vs. 53.3% vs. 27.3%, p < 0.001) rates. The same trend was observed in the 6-month sustained response (63.6% vs. 52.3% vs. 35.6% vs. 22.7%, p = 0.03) and sustained CR (36.4% vs. 44.6% vs. 24.4% vs. 9.1%, p = 0.01). The Kaplan-Meier analysis revealed a shortened duration of remission in the obese group (median duration of remission, not reached vs. 16 months vs. 2 months vs. 1 month, p = 0.002). In multivariate regression analysis, obesity was independently associated with poor initial and sustained responses, and an increased risk for relapse. In conclusion, obesity is a negative predictor for outcomes of corticosteroid treatment. A stratified strategy according to body mass index status may facilitate the precision management of ITP.
MeSH term(s)	Humans ; Purpura, Thrombocytopenic, Idiopathic/complications ; Purpura, Thrombocytopenic, Idiopathic/drug therapy ; Retrospective Studies ; Adrenal Cortex Hormones/therapeutic use ; Treatment Outcome ; Obesity/complications
Chemical Substances	Adrenal Cortex Hormones
Language	English
Publishing date	2023-07-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80077-6
ISSN	1365-2141 ; 0007-1048
ISSN (online)	1365-2141
ISSN	0007-1048
DOI	10.1111/bjh.18997
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Uh III Zs.182: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito