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Article: A Study on China's Tobacco Taxation and Its Influencing Factor on Economic Growth.

Zhao, Shuang

2022 Volume 13, Page(s) 832040

Abstract: Tobacco is a significant product providing considerable economic benefits to countries worldwide, while its increased consumption causes health and socio-economic losses for smokers and non-smokers. This paper constructs a decomposition system of tobacco ...

Abstract	Tobacco is a significant product providing considerable economic benefits to countries worldwide, while its increased consumption causes health and socio-economic losses for smokers and non-smokers. This paper constructs a decomposition system of tobacco taxation: the population aging factor is included in the influencing factors of personal tax, and personal tax revenue is regarded as the product of tax structure, macro tax burden, regional economy, reciprocal aging, and the elderly population. This article conducts an empirical study on the relationship between taxation and economic growth. The estimated coefficients of business tax and corporate income tax are significant at the significance level of 0.1, with a consumption tax and time-variable coefficients reporting a 0.02 level of significance. The T statistic value and the explanatory degree of the variables involved in the model to the explained variables are also very high, reaching more than 95%. We find that increasing the macro tax burden negatively impacts economic growth. Therefore, the study suggests that for fostering the industry's economic growth, the country needs to ensure the optimal macro tax burden of 17.5%, with different types of taxes influencing economic growth. Personal tax reform should pay attention to the phenomenon of aging, adjust the tax structure to increase personal tax income, provide policy support and guarantee for the elderly labor force, and encourage the re-employment of silver-haired people to alleviate the adverse impact of aging on taxation.
Language	English
Publishing date	2022-02-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.832040
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Article ; Online: Impact of COVID 19 Pandemic and Big Data on China's International Trade: Challenges and Countermeasures.

Zhao, Shuang

Frontiers in public health

2022 Volume 10, Page(s) 888335

Abstract: Early 2020 witnessed the coronavirus disease 2019 (COVID-19) pandemic followed by a nationwide lockdown in the whole history for the first time. In this raising dilemma, multiple countries had a serious impact on their international trade, especially ... ...

Abstract	Early 2020 witnessed the coronavirus disease 2019 (COVID-19) pandemic followed by a nationwide lockdown in the whole history for the first time. In this raising dilemma, multiple countries had a serious impact on their international trade, especially during the lockdown. It is also widely accepted that the lives of individuals had been changing ever since the spread of COVID-19. Several other sectors were badly affected during the pandemic. For the above reasons, service industries had a significant impact before and after the pandemic. Based on the data collected, it was identified that the pandemic affected the service industries, enterprises, and other organizations that contribute to the economic growth of the nation. It was also found that the pandemic has adversely impacted private and public enterprises. In addition, the study examined the impact of COVID-19 on China's international trade using artificial intelligence and blockchain technology. Another objective of the article is to examine the impact of big data on China's international trade. The study suggests upgrading the trading policies of China to deal with the challenges being faced in the trading industry.
MeSH term(s)	Artificial Intelligence ; Big Data ; COVID-19/epidemiology ; Commerce ; Communicable Disease Control ; Humans ; Internationality
Language	English
Publishing date	2022-06-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.888335
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Article ; Online: Analysis of Dual Sourcing Strategy with Quality Differentiated Suppliers

Zhao Shuang

E3S Web of Conferences, Vol 253, p

2021 Volume 01057

Abstract: Co-opetition supply chain is now the normal mode of development among enterprises. Based on the co-opetition supply chain, this paper designs a model to study the procurement strategy between OEM and two suppliers with supply uncertainty. We find that ... ...

Abstract	Co-opetition supply chain is now the normal mode of development among enterprises. Based on the co-opetition supply chain, this paper designs a model to study the procurement strategy between OEM and two suppliers with supply uncertainty. We find that the profit increase of OEM is less affected by the wholesale price of a single supplier when purchasing through a single channel suppress. The dual purchase strategy has a great advantage, which leads to price war and reduces wholesale price. However, it is interesting to find that when the technical level of competitive suppliers is constantly improving, the order quantity of competitive suppliers is not always rising, but presents a single peak mode. This shows that OEM can deal with the threat of profit by reducing the orders to competitive suppliers.
Keywords	Environmental sciences ; GE1-350
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
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Article ; Online: Research progress of RNA pseudouridine modification in nervous system.

Chen, Hui / Zhao, Shuang

The International journal of neuroscience

2024 , Page(s) 1–11

Abstract: Recent advances of pseudouridine (Ψ, 5-ribosyluracil) modification highlight its crucial role as a post-transcriptional regulator in gene expression and its impact on various RNA processes. Ψ synthase (PUS), a category of RNA-modifying enzymes, ... ...

Abstract	Recent advances of pseudouridine (Ψ, 5-ribosyluracil) modification highlight its crucial role as a post-transcriptional regulator in gene expression and its impact on various RNA processes. Ψ synthase (PUS), a category of RNA-modifying enzymes, orchestrates the pseudouridylation reaction. It can specifically recognize conserved sequences or structural motifs within substrates, thereby regulating the biological function of various RNA molecules accurately. Our comprehensive review underscored the close association of PUS1, PUS3, PUS7, PUS10, and dyskerin PUS1 with various nervous system disorders, including neurodevelopmental disorders, nervous system tumors, mitochondrial myopathy, lactic acidosis and sideroblastic anaemia (MLASA) syndrome, peripheral nervous system disorders, and type II myotonic dystrophy. In light of these findings, this study elucidated how Ψ strengthened RNA structures and contributed to RNA function, thereby providing valuable insights into the intricate molecular mechanisms underlying nervous system diseases. However, the detailed effects and mechanisms of PUS on neuron remain elusive. This lack of mechanistic understanding poses a substantial obstacle to the development of therapeutic approaches for various neurological disorders based on Ψ modification.
Language	English
Publishing date	2024-02-29
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	3061-2
ISSN	1563-5279 ; 1543-5245 ; 0020-7454
ISSN (online)	1563-5279 ; 1543-5245
ISSN	0020-7454
DOI	10.1080/00207454.2024.2315483
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Article: The Utility of

Zhang, Yun / Hu, Yuxiao / Zhao, Shuang / Huang, Rong

Clinical Medicine Insights. Oncology

2024 Volume 18, Page(s) 11795549231225419

Abstract: Background: Following changes in primary tumor (T) and lymph node (N) staging for nasopharyngeal carcinoma (NPC) in the : Methods: A total of 435 NPC patients underwent : Results: There were significant differences between all parameters relative ... ...

Abstract	Background: Following changes in primary tumor (T) and lymph node (N) staging for nasopharyngeal carcinoma (NPC) in the Methods: A total of 435 NPC patients underwent Results: There were significant differences between all parameters relative to the primary tumor but no significant differences in any parameter relative to the LNM and T stages. Higher mean values of TGN Conclusions: Our findings suggest that metabolic parameters are useful indicators of tumor invasiveness and LNM based on the Eighth Edition manual. Compared with volume-dependent parameters, TGN
Language	English
Publishing date	2024-02-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2577877-8
ISSN	1179-5549
ISSN	1179-5549
DOI	10.1177/11795549231225419
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Article ; Online: Gut microbiome in diabetic retinopathy: A systematic review and meta-analysis.

Zhao, Shuang / Yan, Qi / Xu, Wanjing / Zhang, Juanmei

Microbial pathogenesis

2024 Volume 189, Page(s) 106590

Abstract: Context: Changes in the gut microbiome are linked with Type 2diabetes mellitus (T2DM) development, but alterations in patients with diabetic retinopathy (DR) are still being debated.: Objective: To investigate the differences in biodiversity and ... ...

Abstract	Context: Changes in the gut microbiome are linked with Type 2diabetes mellitus (T2DM) development, but alterations in patients with diabetic retinopathy (DR) are still being debated. Objective: To investigate the differences in biodiversity and relative abundance of gut microbiome between patients with DR and T2DM. Methods: A comprehensive search was performed in five electronic databases (PubMed, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science, and CNKI) from the inception of each database through to August 2023. The standardized mean difference (SMD) and its 95% confidence interval (CI) were estimated using Stata 15.1. Furthermore, the alpha diversity index and relative abundance of the gut microbiome were calculated. The Egger test determined publication bias in the literature. Results: Seven case-control studies were included in the final dataset, comprising 195 patients with DR and 211 patients with T2DM. Compared to T2DM patients, patients in the DR group had a reduced but not significantly different α-diversity. The analysis of microbial composition at the phylum level revealed a marked increase in the relative abundance of Bacteroidetes(ES = 23.27, 95%CI[8.30, 38.23], P = 0.000) and a decline in Firmicutes(ES = 47.05, 95%CI[36.58, 57.52], P = 0.000), Proteobacteria (ES = 11.08, 95%CI[6.08, 16.07], P = 0.000) and Actinobacteria (ES = 10.43, 95%CI[1.64, 19.22], P = 0.001) in patients with DR when compared to those with T2DM. Conclusions: An association exists between alterations in the gut microbiome of T2DM and the development and progression of DR. This suggests that re-establishing homeostasis of the gut microbiome could be a potential way to prevent or treat DR and requires further confirmation in future studies. Registration database: Prospero. Registration number: CRD42023455280.
MeSH term(s)	Humans ; Diabetic Retinopathy ; Diabetes Mellitus, Type 2/complications ; Gastrointestinal Microbiome ; Case-Control Studies
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2024.106590
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Article ; Online: New application of traditional S retractor in collecting wound flushing fluid after skin tumour resection.

Liu, Yuancheng / Zhao, Shuang / Liu, Xin / Hu, Xiheng

International wound journal

2024 Volume 21, Issue 3, Page(s) e14813

Abstract: After Skin tumour resection, there may be residual tumour cells on the wound surface, washing the wound surface with sterilized water can mediate tumour cell lysis and improve patient prognosis. We observed that when the patient is lying behind the ... ...

Abstract	After Skin tumour resection, there may be residual tumour cells on the wound surface, washing the wound surface with sterilized water can mediate tumour cell lysis and improve patient prognosis. We observed that when the patient is lying behind the operating table, both the limbs and trunk will form an inclined plane with a high centre and a low periphery. Fit the hook of the traditional S retractor onto the low end of the inclined surface, and apply appropriate pressure to make the fitting tight. This way, the flushing fluid will converge at the low end of the fitting surface and will not leak out. Combined with a negative pressure aspirator, it can reduce the splashing of flushing fluid. The traditional S retractor is common in the operating room, which is easy to operate and do not increase medical costs. The method of using a traditional S retractor to collect flushing fluid is worth further promotion.
MeSH term(s)	Humans ; Skin Neoplasms ; Skin ; Operating Rooms ; Cell Death ; Extremities
Language	English
Publishing date	2024-03-13
Publishing country	England
Document type	Letter
ZDB-ID	2170920-8
ISSN	1742-481X ; 1742-4801
ISSN (online)	1742-481X
ISSN	1742-4801
DOI	10.1111/iwj.14813
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Article ; Online: Validation of the 2018 FIGO staging system for stage IIIC cervical cancer by determining the metabolic and radiomic heterogeneity of primary tumors based on

Zhang, Yun / Hu, Yuxiao / Zhao, Shuang / Xu, Shanshan

Abdominal radiology (New York)

2024

Abstract: Purpose: This study aimed to validate the 2018 FIGO staging system of cervical cancer (CC) by determining the metabolic and radiomic heterogeneity of primary tumors between stage IIIC1 and IIIC2.: Methods: 168 patients with squamous cell CC underwent ...

Abstract	Purpose: This study aimed to validate the 2018 FIGO staging system of cervical cancer (CC) by determining the metabolic and radiomic heterogeneity of primary tumors between stage IIIC1 and IIIC2. Methods: 168 patients with squamous cell CC underwent pre-treatment fluorine-18 fluorodeoxyglucose positron emission computed tomography ( Results: The IIIC1 and IIIC2 groups did not differ significantly in age, weight, height, or the 10 major metabolic parameters (P > 0.05). The AUCs of the 4 models were 0.577, 0.639, 0.763, and 0.506, respectively, in the training cohort, and 0.789, 0.699, 0.761, and 0.538, respectively, in the testing cohort. The model fit of the logistic regression model based on CT + PET data was good in both the training and testing cohorts. Conclusion: Our study offers additional diagnostic options for PALN metastasis, which could impact treatment decisions. Our results indirectly support the conclusions of previous studies recommending that primary tumors should be considered during IIIC staging.
Language	English
Publishing date	2024-03-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-024-04226-7
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Article ; Online: mRNA and protein of p33ING1 in normal and cancer tissues.

Zhao, Shuang / Zheng, Hua-Chuan

Translational cancer research

2022 Volume 9, Issue 5, Page(s) 3623–3633

Abstract: Background: Inhibitor growth protein 1 (ING1) is a tumor suppressor, and its down-regulation is involved in the progression and aggressive phenotypes of human malignancies through its interactions with the H3K4me3 and p53.: Methods: We collected ... ...

Abstract	Background: Inhibitor growth protein 1 (ING1) is a tumor suppressor, and its down-regulation is involved in the progression and aggressive phenotypes of human malignancies through its interactions with the H3K4me3 and p53. Methods: We collected datasets to analyze the relationship between ING1b mRNA expression and accumulative survival rate, and carried out immunohistochemistry analyses to determine the expression profiles of the p33ING1 protein on the mouse, normal human, and human cancer tissue microarrays. Results: Compared with normal tissues, the ING1b mRNA was highly expressed in various types of cancer tissues, including, colorectal, lung, and breast cancers, and was positively correlated with the overall survival rate of gastric cancer patients. In mouse tissues, the subcellular location of p33ING1 was frequently nuclear; however, it was occasionally cytoplasmic or nucleocytoplasmic. There was a positive detection in the neuron body, a part of glial cells, the glandular epithelium of the stomach, intestines, breast, hepatocytes, heart, skeletal muscle cells, the bronchial and alveolar epithelium, and nephric tubules. In human tissues, the p33ING1 protein, apart from its cytoplasmic distribution, was distributed in the nuclei of the tongue, esophagus, stomach, intestine, lung, trachea, skin, appendix, cervix, endometrium, ovary, and breast. p33ING1 immunoreactivity was strongly detected in the stomach, trachea, skin, cervix, and breast, while it was weak in the other tissues. The positive rate of p33ING1 was 41.0% in the tested cancer entities (489/1,194). In general, p33ING1 expression was restricted to only the cytoplasm for all cancers, whereas it was found in the nucleus of renal clear cells, ovarian and colorectal cancers. Among them, p33ING1 was expressed in more than half of squamous cell carcinomas derived from the esophagus and cervix, while it was rarely expressed in hepatocellular (21.0%) and renal clear cell carcinoma (19.4%). Conclusions: The findings suggest that p33ING1 might be participated in the repair and regeneration of organs or tissues the repair and regeneration of organs or tissue, and the carcinogenesis of the highly proliferative epithelium.
Language	English
Publishing date	2022-01-15
Publishing country	China
Document type	Journal Article
ZDB-ID	2901601-0
ISSN	2219-6803 ; 2218-676X
ISSN (online)	2219-6803
ISSN	2218-676X
DOI	10.21037/tcr.2020.04.28
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Article ; Online: New insights into small non-coding RNAs during spermatogenesis.

Wang, Xin / Zhang, Zhen-Yi / Zhao, Shuang / Liu, Mo-Fang

Science bulletin

2024

Language	English
Publishing date	2024-02-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2816140-3
ISSN	2095-9281 ; 2095-9273
ISSN (online)	2095-9281
ISSN	2095-9273
DOI	10.1016/j.scib.2024.02.019
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