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  1. Article ; Online: Effects of

    Zhang, Jiayan / Liu, Yuhao / Liu, Mengting / Zhao, Yansheng / Zhu, Ying / Cui, Shumao / Xiao, Xiang

    Food & function

    2024  Volume 15, Issue 4, Page(s) 1923–1937

    Abstract: The effects of fermentation on barley starch were studied ... ...

    Abstract The effects of fermentation on barley starch were studied using
    MeSH term(s) Starch/chemistry ; Amylopectin/chemistry ; Hordeum/chemistry ; Fermentation ; Amylose/chemistry
    Chemical Substances Starch (9005-25-8) ; Amylopectin (9037-22-3) ; Amylose (9005-82-7)
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo04395a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Multiple databases analyzed the prognosis prediction of renin secretion pathway-related genes in renal clear cell carcinoma and immunotherapy.

    Li, Hubo / Bao, Xinghua / Xiao, Yonggui / Cao, Fenghong / Han, Xiaoyan / Zhao, Yansheng / Kang, Shaosan

    Translational cancer research

    2024  Volume 13, Issue 1, Page(s) 217–230

    Abstract: Background: Clear cell renal cell carcinoma (ccRCC) is a malignant kidney tumour and its progression is associated with the renin secretion pathway, so this study aimed to develop a prognostic model based on renin secretion pathway-related genes.: ... ...

    Abstract Background: Clear cell renal cell carcinoma (ccRCC) is a malignant kidney tumour and its progression is associated with the renin secretion pathway, so this study aimed to develop a prognostic model based on renin secretion pathway-related genes.
    Methods: First, 453 renin secretion pathway-related genes were acquired [|log fold change (FC)| >1.5, false discovery rate (FDR) <0.05] from The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) databases. The data were combined and further screened for 188 genes associated with ccRCC prognosis (P<0.05) by univariate independent prognostic analysis. These genes were subjected to least absolute shrinkage and selection operator regression to identify potential prognostic genes to construct the prognostic model. The stability of the model was externally validated. Combined risk scores and clinical information were used to create nomograms to accurately reflect patient survival. The model-related genes were further mined for subsequent analysis.
    Results: A prognostic model of six renin secretion pathway genes (
    Conclusions: The prognostic model of ccRCC based on six renin secretion pathway-related genes can be used to guide the precise treatment of ccRCC patients.
    Language English
    Publishing date 2024-01-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr-23-1254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Application of environmental-safe fermentation with Saccharomyces cerevisiae for increasing the cinnamon biological activities.

    Darwesh, Osama M / Eweys, Aya S / Zhao, Yan-Sheng / Matter, Ibrahim A

    Bioresources and bioprocessing

    2023  Volume 10, Issue 1, Page(s) 12

    Abstract: The effect of fermentation by Saccharomyces cerevisiae on biological properties of cinnamon (Cinnamomum cassia) was investigated. The study demonstrated that the extract of S. cerevisiae-fermented cinnamon (S.C.FC) has antioxidants higher than non- ... ...

    Abstract The effect of fermentation by Saccharomyces cerevisiae on biological properties of cinnamon (Cinnamomum cassia) was investigated. The study demonstrated that the extract of S. cerevisiae-fermented cinnamon (S.C.FC) has antioxidants higher than non-fermented one. The optimum results for antioxidant yield were noted with 10
    Language English
    Publishing date 2023-02-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2785482-6
    ISSN 2197-4365 ; 2197-4365
    ISSN (online) 2197-4365
    ISSN 2197-4365
    DOI 10.1186/s40643-023-00632-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Improving the antioxidant and anticancer potential of

    Eweys, Aya S / Zhao, Yan-Sheng / Darwesh, Osama M

    Biotechnology reports (Amsterdam, Netherlands)

    2022  Volume 36, Page(s) e00768

    Abstract: This study designed to investigate effect of fermentation ... ...

    Abstract This study designed to investigate effect of fermentation by
    Language English
    Publishing date 2022-10-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2801018-8
    ISSN 2215-017X
    ISSN 2215-017X
    DOI 10.1016/j.btre.2022.e00768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Construction of a polymer-based fluorescent probe with dual responsive sites for monitoring changes of lysosomal viscosity.

    Yu, Faqi / Fan, Ruiyang / Zhao, Yansheng / Chen, Yijun / Kong, Xiuqi / Lin, Weiying

    Journal of materials chemistry. B

    2023  Volume 11, Issue 48, Page(s) 11620–11625

    Abstract: As highly dynamic organelles, lysosomes are involved in various physiological processes. The viscosity of lysosomes plays critical roles in maintaining their normal physiological function and abnormal variations of viscosity are associated with many ... ...

    Abstract As highly dynamic organelles, lysosomes are involved in various physiological processes. The viscosity of lysosomes plays critical roles in maintaining their normal physiological function and abnormal variations of viscosity are associated with many diseases. Monitoring the changes of lysosomal viscosity could contribute to understanding lysosome-related physiological and pathological processes. In this work, based on an indole fluorophore and fluorescent polymer, poly(2-hydroxyethyl methacrylate) (PHEM), a new polymeric fluorescent probe, In-PHEM, with dual responsive sites for tracking changes of lysosomal viscosity is presented. In-PHEM showed excellent fluorescence properties and high photostability. With this robust probe, the variation of the lysosomal viscosity in cells under different physiological conditions, including inducer stimulation, the process of starvation and apoptosis, was monitored using dual-channel imaging. Therefore, this work may provide a powerful tool for monitoring changes of lysosomal viscosity and helping to understand the relationship between the viscosity changes of lysosomes and their related diseases.
    MeSH term(s) Humans ; Fluorescent Dyes ; Viscosity ; HeLa Cells ; Diagnostic Imaging ; Lysosomes
    Chemical Substances Fluorescent Dyes
    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d3tb02232c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Long noncoding RNA

    Jia, Mingfei / Chen, Xi / Kang, Shaosan / Cao, Fenghong / Zhao, Yansheng / Zhang, Liguo / Bao, Xinghua / Wang, Lei / Li, Hengran / Li, Chenggang

    Translational andrology and urology

    2024  Volume 13, Issue 2, Page(s) 230–244

    Abstract: Background: Clear cell renal cell carcinoma (RCC) is the most common subtype of RCC. Although targeted therapy can provide superior treatment outcomes, it is prone to drug resistance, and individual responses to immunotherapy vary greatly. Therefore, ... ...

    Abstract Background: Clear cell renal cell carcinoma (RCC) is the most common subtype of RCC. Although targeted therapy can provide superior treatment outcomes, it is prone to drug resistance, and individual responses to immunotherapy vary greatly. Therefore, finding new diagnostic and therapeutic targets for RCC is of considerable importance. Long noncoding RNA (lncRNA)
    Methods: Small interfering RNA (siRNA) and plasmid cloning DNA (pcDNA) 3.1 were used to transfect renal cancer cell line 786-0 to silence and overexpress the lncRNA
    Results: Compared with blank control group and negative control group, the siGPRC5D-AS1 group showed a significant decrease in the relative expression of lncRNA
    Conclusions: Silencing the expression of lncRNA
    Language English
    Publishing date 2024-02-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 2851630-8
    ISSN 2223-4691 ; 2223-4691 ; 2223-4683
    ISSN (online) 2223-4691
    ISSN 2223-4691 ; 2223-4683
    DOI 10.21037/tau-23-624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Changes in the structural, physicochemical and functional properties and

    Xiao, Xiang / Li, Xiaodong / Bai, Juan / Fan, Songtao / Daglia, Maria / Li, Jiaying / Ding, Yiwei / Zhang, Yanshun / Zhao, Yansheng

    Food & function

    2024  Volume 15, Issue 8, Page(s) 4276–4291

    Abstract: Fermentation is an effective method for improving the nutritional quality and functional characteristics of grains. This study investigated changes in the structural, physicochemical, and functional properties of fermented barley dietary fiber (FBDF) ... ...

    Abstract Fermentation is an effective method for improving the nutritional quality and functional characteristics of grains. This study investigated changes in the structural, physicochemical, and functional properties of fermented barley dietary fiber (FBDF) exerted by
    MeSH term(s) Dietary Fiber/metabolism ; Dietary Fiber/analysis ; Hordeum/chemistry ; Fermentation ; Feces/microbiology ; Humans ; Gastrointestinal Microbiome ; Digestion ; Antioxidants/metabolism ; Fatty Acids, Volatile/metabolism ; Lactobacillus plantarum/metabolism ; Phenols/metabolism
    Chemical Substances Dietary Fiber ; Antioxidants ; Fatty Acids, Volatile ; Phenols
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo05605h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cinnamaldehyde Alleviates the Oxidative Stress of Caenorhabditis elegans in the Presence of Lactic Acid.

    Zhao, Yansheng / Xiao, Mei / Eweys, Aya Samy / Bai, Juan / Darwesh, Osama M / Xiao, Xiang

    Plant foods for human nutrition (Dordrecht, Netherlands)

    2023  Volume 78, Issue 4, Page(s) 683–690

    Abstract: Cinnamaldehyde is an excellent natural antioxidant with high antioxidant activity, but its function in food or human digestive tract under acidic conditions remains to be studied. The effects of cinnamaldehyde in the presence of lactic acid on oxidative ... ...

    Abstract Cinnamaldehyde is an excellent natural antioxidant with high antioxidant activity, but its function in food or human digestive tract under acidic conditions remains to be studied. The effects of cinnamaldehyde in the presence of lactic acid on oxidative stress of Caenorhabditis elegans and the underlying molecular mechanisms were investigated in the present study. Results showed that cinnamaldehyde with or without lactic acid exhibited good antioxidant ability, represented by high SOD and CAT activities in C. elegans, while lactic acid exerted no effect on the antioxidant enzymes. Trace elements, like Cu, Fe, or Se, are important for the activities of antioxidant enzymes. Data of metal elements analysis revealed that cinnamaldehyde made big differences on the levels of Mn, Cu, Se of worms compared with single lactic acid treatment. Moreover, mechanistic study suggested that in the presence of lactic acid, cinnamaldehyde could enhance the expressions of akt-2, age-1 to increase the antioxidant activities. In addition, we found that lactic acid was able to change the metabolic profile of cinnamaldehyde in C. elegans, characterized by nucleosides and amino acids, which were involved in the purine metabolism, the biosynthesis, and metabolism of some amino acids, etc. This study provides a theoretical basis for further revealing the functional activity and mechanism of cinnamaldehyde under acidic conditions.
    MeSH term(s) Animals ; Humans ; Infant ; Caenorhabditis elegans/metabolism ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Lactic Acid/metabolism ; Lactic Acid/pharmacology ; Superoxide Dismutase/metabolism ; Oxidative Stress ; Amino Acids/metabolism ; Reactive Oxygen Species/metabolism
    Chemical Substances Antioxidants ; cinnamaldehyde (SR60A3XG0F) ; Lactic Acid (33X04XA5AT) ; Superoxide Dismutase (EC 1.15.1.1) ; Amino Acids ; Reactive Oxygen Species
    Language English
    Publishing date 2023-09-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 188869-9
    ISSN 1573-9104 ; 0377-3205
    ISSN (online) 1573-9104
    ISSN 0377-3205
    DOI 10.1007/s11130-023-01094-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 967: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Article ; Online: Heterologous expression and enzymatic characteristics of sulfatase from

    Cheng, Zhangchen / Wu, Beiqi / Bai, Juan / Fan, Songtao / Daglia, Maria / Li, Jiaying / Zhao, Yansheng / He, Yufeng / Zhu, Lin / Xiao, Xiang

    Food & function

    2024  Volume 15, Issue 10, Page(s) 5439–5449

    Abstract: Barley, rich in bioactive components including dietary fiber, polyphenolic compounds and functional proteins, exhibits health benefits such as regulating glucose and lipid metabolism. Previous studies have found that the content and composition of free ... ...

    Abstract Barley, rich in bioactive components including dietary fiber, polyphenolic compounds and functional proteins, exhibits health benefits such as regulating glucose and lipid metabolism. Previous studies have found that the content and composition of free phenolic acids in barley may be significantly changed by fermentation with the laboratory patented strain
    MeSH term(s) Lactobacillus plantarum/enzymology ; Lactobacillus plantarum/metabolism ; Lactobacillus plantarum/genetics ; Sulfatases/metabolism ; Sulfatases/genetics ; Sulfatases/chemistry ; Hordeum ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/chemistry ; Fermentation ; Hydroxybenzoates/metabolism ; Hydrogen-Ion Concentration ; Escherichia coli/genetics ; Temperature ; Dietary Fiber/metabolism
    Chemical Substances phenolic acid
    Language English
    Publishing date 2024-05-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2612033-1
    ISSN 2042-650X ; 2042-6496
    ISSN (online) 2042-650X
    ISSN 2042-6496
    DOI 10.1039/d3fo04616h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Momordica charantia

    Xiao, Xiang / Huang, Shiting / Yang, Zihan / Zhu, Ying / Zhu, Lin / Zhao, Yansheng / Bai, Juan / Kim, Kee-Hong

    Journal of medicinal food

    2024  

    Abstract: Momordica ... ...

    Abstract Momordica charantia
    Language English
    Publishing date 2024-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1427365-2
    ISSN 1557-7600 ; 1096-620X
    ISSN (online) 1557-7600
    ISSN 1096-620X
    DOI 10.1089/jmf.2024.k.0037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5916: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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