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Article ; Online: Clinical Trials Studying Suicide Risk Reduction: Who is Excluded From Participation.

Lawrence, Ryan E / Jaffe, Chaya / Zhao, Yinjun / Wang, Yuanjia / Goldberg, Terry E

Archives of suicide research : official journal of the International Academy for Suicide Research

2024 , Page(s) 1–14

Abstract: Objective: The use of exclusion criteria in clinical trials can cause research participants to differ markedly from clinical populations, which negatively impacts generalizability of results. This study identifies and quantifies common and recurring ... ...

Abstract	Objective: The use of exclusion criteria in clinical trials can cause research participants to differ markedly from clinical populations, which negatively impacts generalizability of results. This study identifies and quantifies common and recurring exclusion criteria in clinical trials studying suicide risk reduction, and estimates their impact on eligibility among a clinical sample of adults in an emergency department with high suicide risk. Method: Recent trials were identified by searching PubMed (terms suicide, efficacy, effectiveness, limited to clinical trials in prior 5 years). Common exclusion criteria were identified using Qualitative Content Analysis. A retrospective chart review examined a one-month sample of all adults receiving psychiatric evaluation in a large urban academic emergency department. Results: The search yielded 27 unique clinical trials studying suicide risk reduction as a primary or secondary outcome. After research fundamentals (e.g. informed consent, language fluency), the most common exclusion criteria involved psychosis (77.8%), cognitive problems (66.7%), and substance use (63.0%). In the clinical sample of adults with high suicide risk ( Conclusions: Recent clinical trials studying suicide risk reduction have low generalizability to emergency psychiatry patients with high suicide risk. Trials enrolling persons with psychosis and substance use in particular are needed to improve generalizability to this clinical population.
Language	English
Publishing date	2024-02-28
Publishing country	England
Document type	Journal Article
ZDB-ID	1283671-0
ISSN	1543-6136 ; 1381-1118
ISSN (online)	1543-6136
ISSN	1381-1118
DOI	10.1080/13811118.2024.2322128
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Zs.A 4465: Show issues

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Article ; Online: Spatiotemporal variation in heatwaves and elderly population exposure across China.

Zhou, Yun / Gu, Songwei / Yang, Hong / Li, Yao / Zhao, Yinjun / Li, Yuechen / Yang, Qingyuan

The Science of the total environment

2024 Volume 917, Page(s) 170245

Abstract: Heatwaves have been intensified worldwide due to climate change, posing great health risks, especially to elderly populations. However, in China, limited studies have employed the heat index to decipher the spatiotemporal trends of heatwaves and their ... ...

Abstract	Heatwaves have been intensified worldwide due to climate change, posing great health risks, especially to elderly populations. However, in China, limited studies have employed the heat index to decipher the spatiotemporal trends of heatwaves and their impacts on the elderly population. By comparing the three heatwave definitions, this study aimed to evaluate the long-term spatiotemporal variations in heatwaves from 1964 to 2022 across China using the Excess Heat Factor (EHF). We took advantage of high-resolution reanalysis temperature data on the Google Earth Engine (GEE) platform to efficiently calculate the heatwaves. Our results revealed that the frequency and duration of heatwaves increased significantly in approximately 77 % of China's total area, with South China experiencing the most frequent and prolonged heatwaves. Conversely, in most areas, no significant trend was discerned in the growth of the maximum and average heatwave intensities. The total number of elderly people affected by heatwaves surged from approximately 11.96 million in 2001 to over 30.31 million in 2020, with an estimated additional 1.12 million older adults exposed to heatwaves annually across the nation (R
MeSH term(s)	Humans ; Aged ; Hot Temperature ; Temperature ; China ; Climate Change
Language	English
Publishing date	2024-01-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2024.170245
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Article ; Online: Changes in the hydrological and sediment regimes of two neighboring catchments in the past sixty years

Zhao, Yinjun / Wang, Sheng / Li, Jiaxu / Ding, Aizhong / Wei, Yongping

Catena. 2023, p.107248-

2023 , Page(s) 107248–

Abstract: Despite advances in watershed hydrology research, little is known about the hydrologic differences and similarities between neighboring catchments. Two neighboring catchments, the Nanliu River catchment (NLRC) and the Qinjiang River catchment (QJRC), ... ...

Abstract	Despite advances in watershed hydrology research, little is known about the hydrologic differences and similarities between neighboring catchments. Two neighboring catchments, the Nanliu River catchment (NLRC) and the Qinjiang River catchment (QJRC), were studied to see how they differed in annual precipitation, runoff, and sediment load in the last 60 years. Four hydrological signatures (river regime, periodicity, change trends, and precipitation-runoff-sediment correlations) estimated from a wide variety of catchment classification and corresponding indices, such as the runoff ratio (RQP) and baseflow index (BFI). The findings revealed that the two catchments shared similar general features, including similar runoff patterns (RQP= 0.45 and 0.43, and BFI = 2.83% and 2.12% in NLRC and QJRC respectively), minor differences in periodicities, and similar annual precipitation, runoff, and sediment load changes. The annual sediment load has been steadily decreasing due to human activity. The simple precipitation-runoff regression model developed in one catchment can be transferred to another. Nash-Sutcliffe efficiency (NSE) coefficients were 0.79 and 0.62, respectively. The runoff-sediment load regression model, on the other hand, showed poor performance (NSE of -0.34 and -0.99, respectively), despite capturing the main patterns with correlation coefficients of 0.82 (p<0.001) and 0.74 (p<0.001), respectively. These findings suggested that (1) annual runoff ratios are influenced more by climate (particularly precipitation) than by surface and subsurface characteristics of the earth. The rainfall-runoff model for the neighboring catchment can recreate runoff dynamics at yearly scales. Human activities, such as dam construction and sand mining, significantly impacted the annual sediment yield. (2) The two neighboring catchments had similar hydrologic ages because of similar climate, geology, tectonics, and human disturbance. These findings provided a solid evidence for predicting runoff and sediment in ungauged basins.
Keywords	anthropogenic activities ; atmospheric precipitation ; base flow ; catenas ; climate ; humans ; hydrologic models ; periodicity ; regression analysis ; rivers ; runoff ; sand ; sediment contamination ; sediment yield ; tectonics ; watershed hydrology ; watersheds ; Catchment hydrology ; Hydrological signatures ; Catchment coevolution ; Third Law of Geography
Language	English
Publishing place	Elsevier B.V.
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	519608-5
ISSN	1872-6887 ; 0008-7769 ; 0341-8162
ISSN (online)	1872-6887 ; 0008-7769
ISSN	0341-8162
DOI	10.1016/j.catena.2023.107248
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Article ; Online: Eligibility of emergency psychiatry patients for clinical trials studying depression.

Lawrence, Ryan E / Bernstein, Adam / Jaffe, Chaya / Zhao, Yinjun / Wang, Yuanjia / Goldberg, Terry E

Journal of affective disorders

2023 Volume 342, Page(s) 10–15

Abstract: Background: Differences often exist between people with depression who are eligible for clinical trials and those seen in clinical practice. The impact of exclusion criteria on eligibility has been previously reported for inpatients and outpatients, but ...

Abstract	Background: Differences often exist between people with depression who are eligible for clinical trials and those seen in clinical practice. The impact of exclusion criteria on eligibility has been previously reported for inpatients and outpatients, but has not been assessed for emergency psychiatry patients; a group that overlaps with inpatients and outpatients but also has important distinctives. Understanding the frequencies of commonly used exclusion criteria in this population could inform interpretation of existing data (generalizability) and highlight opportunities/needs for future trials. Methods: We reviewed 67 clinical trials studying depression using Qualitative Content Analysis to identify common and recurring exclusion criteria. We examined the frequency of these exclusion criteria among a clinical sample of emergency psychiatry patients. Results: Most clinical trials had exclusions for basic research requirements, age, symptom severity, psychosis, and substance use. Applying 9 commonly used exclusion criteria to the clinical population resulted in a 3.3 % eligibility rate (95 % CI 1.2 %-7.0 %). Exclusions for psychosis (85.1 % of trials), substance use (83.6 % of trials), and suicide risk (65.7 % of trials) would likely exclude 93 % of emergency psychiatry patients. The prevalence of psychosis, substance use, and suicide risk was much higher among emergency psychiatry patients than among previously studied populations. Limitations: Some eligibility criteria could not be measured. The Qualitative Content Analysis consolidated similar exclusion criteria, losing potentially important nuances in wordings. Conclusions: Exclusion criteria commonly used in contemporary clinical trials of depression limit generalizability to emergency psychiatry patients, due in large part to exclusions for psychosis, substance use, and suicide risk.
MeSH term(s)	Humans ; Depression ; Outpatients ; Patient Selection ; Psychiatry ; Research Design ; Clinical Trials as Topic
Language	English
Publishing date	2023-09-07
Publishing country	Netherlands
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2023.09.010
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Zs.A 1485: Show issues

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Article ; Online: Afforestation changed the fungal functional community of paddy fields and dry farmlands differently.

Chen, Lijuan / Wei, Yuxi / Li, Changsheng / Zhao, Yinjun / Wei, Yongping / Xue, Yuanyuan / Feng, Qi

The Science of the total environment

2023 Volume 904, Page(s) 166758

Abstract: Afforestation currently makes a great contribution to carbon uptake in terrestrial ecosystems, while dramatically affects soil ecosystem functions too. Little is known, however, about the changes in soil fungal functional groups and their interactions ... ...

Abstract	Afforestation currently makes a great contribution to carbon uptake in terrestrial ecosystems, while dramatically affects soil ecosystem functions too. Little is known, however, about the changes in soil fungal functional groups and their interactions following afforestation. Here, based on high-throughput sequencing and FUNGuild annotation, we investigated the functional characteristics of soil fungi as well as environmental factors in a watershed where paddy field and dry farmland were changed to eucalyptus plantation. The results showed that afforestation on paddy field resulted in greater changes in diversity, community structure and taxon interactions of fungal functional groups than afforestation on dry farmland. The most complex and distinctive community structure was found in eucalyptus plantation, as well as the greatest taxon interactions, and the lowest alpha-diversity of functional guilds of symbiotrophic fungi because of the dominant ectomycorrhizal fungi. Paddy field exhibited the highest proportion of saprotrophic fungi, but the lowest taxonomic diversity of saprotrophic and pathotrophic fungi. The taxonomic diversity of undefined saprotrophic fungi shaped the differences in community structure and network complexity between eucalyptus plantation and cropland. Limited cooperation within dominant fungi was the main reason for the establishment of a loose co-occurrence network in paddy field. From croplands to artificial forests, reduced soil pH boosted the taxonomic diversity of fungal functional groups. All of these findings suggested that afforestation may lead to an increase in the taxonomic diversity of soil fungal functional groups, which would further intensify the taxon interactions.
MeSH term(s)	Ecosystem ; Farms ; Fungi ; Soil Microbiology ; Soil/chemistry ; Forests ; Mycorrhizae
Chemical Substances	Soil
Language	English
Publishing date	2023-09-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.166758
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Zs.A 949: Show issues

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Article ; Online: Potential impact of polyethylene microplastics on the growth of water spinach (Ipomoea aquatica F.): Endophyte and rhizosphere effects

Yu, Fangming / Fu, Mingyue / Tang, Chijian / Mo, Cuiju / Li, Songyin / Luo, Shiyu / Qin, Peiqing / Zhao, Yinjun / Li, Yi

Chemosphere. 2023 Apr. 19, p.138737-

2023 , Page(s) 138737–

Abstract: Microplastic contamination has received much attention, especially in agroecosystems. However, since edible crops with different genetic backgrounds may present different responses to microplastics, more research should be conducted and focused on more ... ...

Abstract	Microplastic contamination has received much attention, especially in agroecosystems. However, since edible crops with different genetic backgrounds may present different responses to microplastics, more research should be conducted and focused on more edible crops. In the current study, pot experiments were conducted to investigate the potential impact of polyethylene microplastic (PE) (particle sizes: 0.5 μm and 1.0 μm, addition levels: 0 (control), 0.5% and 1.0% (w/w)) addition on the physiological and biochemical variations of I. aquatica F. The results indicated that PE addition caused an increase in the soil pH and NH₄⁺-N and soil organic matter contents, which increased by 10.1%, 29.9% and 50.1% when PE addition at A10P0.5 level (10 g (PE) kg⁻¹ soil, particle size: 0.5 μm). While, PE exposure resulted in a decrease in soil available phosphorus and total phosphorus contents, which decreased by 53.9% and 10.5% when PE addition at A10P0.5 level. In addition, PE addition altered the soil enzyme activities. Two-way ANOVA indicated that particle size had a greater impact on the variations in soil properties and enzyme activities than the addition level. PE addition had a strong impact on the rhizosphere microbial and root endophyte community diversity and structure of I. aquatica F. Two-way ANOVA results indicated that the particle size and addition level significantly altered the α-diversity indices of both rhizosphere microbial and root endophyte (P < 0.05, P < 0.01 or P < 0.001). Moreover, PE was adsorbed by I. aquatica F., which was clearly observed in the transverse roots and significantly increased the H₂O₂, ·O₂⁻, malondialdehyde and ascorbic acid contents in both the roots and aerial parts of I. aquatica F., leading to a decrease in I. aquatica F. biomass. Overall, the current study enriches the understanding of the effect of microplastics on edible crops.
Keywords	Ipomoea aquatica ; agroecosystems ; ascorbic acid ; endophytes ; enzymes ; malondialdehyde ; microplastics ; particle size ; phosphorus ; polyethylene ; rhizosphere ; soil enzymes ; soil organic matter ; soil pH ; total phosphorus ; Polyethylene microplastics ; Ipomoea aquatica F. ; Oxidative damage ; Root endophyte
Language	English
Dates of publication	2023-0419
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2023.138737
Database	NAL-Catalogue (AGRICOLA)

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Zs.A 2540: Show issues

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Article: Quantifying sediment retention by high-density small water conservancy facilities under insignificant variation of water discharge in the Nanliu River Basin, Beibu Gulf

Tong, Kai / Zhao, Yinjun / Wei, Yongping / Hu, Baoqing / Deng, Jianming / Xie, Yuchu

Journal of hydrology. 2022 Oct., v. 43

2022

Abstract: The Nanliu River Basin in Beibu Gulf, China. The variations in water discharge and sediment load were analysed for 1961–2015. In addition, sediment retention by high-density small water conservancy facilities in the tributaries was estimated by a ... ...

Abstract	The Nanliu River Basin in Beibu Gulf, China. The variations in water discharge and sediment load were analysed for 1961–2015. In addition, sediment retention by high-density small water conservancy facilities in the tributaries was estimated by a hydrological model with different scenarios. At the end of the study, the variation in the relationship between water discharge and suspended sediment concentration (SSC) and the impact on riverbeds were analysed. The sediment load showed a dramatically decreasing trend, and an abrupt change point in 1988 was detected by a Mann–Kendall test. Compared to the baseline period (1961–1988), the sediment load in the altered period (1989–2015) decreased by 41.7%. By employing the SWAT model with different scenarios, sediment retention by high-density small water conservancy facilities in the tributaries was estimated in the basin, with a mean value of 457.1 × 10³ tons/yr during the altered period. The construction of water conservancy facilities has been the key driver of the significant reduction in sediment load observed in the Nanliu River. The rating curves of monthly SSC–discharge showed clockwise patterns, which were different from the Yangtze River’s counter-clockwise pattern. SSC reductions and excessive sand mining in the main channel have strongly affected riverbeds, leading to a year-by-year drop.
Keywords	Soil and Water Assessment Tool model ; basins ; rivers ; sand ; sediment contamination ; suspended sediment ; water conservation ; watersheds ; China ; Yangtze River
Language	English
Dates of publication	2022-10
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2814784-4
ISSN	2214-5818
ISSN	2214-5818
DOI	10.1016/j.ejrh.2022.101184
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Article: Contrasting trends between peak photosynthesis timing and peak greenness timing across seven typical biomes in Northern Hemisphere mid-latitudes

Ge, Zhongxi / Huang, Jing / Wang, Xufeng / Tang, Xuguang / Fan, Lei / Zhao, Yinjun / Ma, Mingguo

Agricultural and forest meteorology. 2022 Aug. 15, v. 323

2022

Abstract: The peak photosynthesis timing (PPT) is a key factor that affects the seasonality of the terrestrial carbon uptake. Carbon phenology derived from gross primary production (GPP) has been used to validate the peak greenness timing (PGT) from satellite- ... ...

Abstract	The peak photosynthesis timing (PPT) is a key factor that affects the seasonality of the terrestrial carbon uptake. Carbon phenology derived from gross primary production (GPP) has been used to validate the peak greenness timing (PGT) from satellite-based vegetation indices (VIs) in phenology research. However, PPT, derived from GPP, has not been comprehensively analyzed, especially taking different GPP estimates, fitting methods, and biomes into account. Moreover, whether or not the PPT trend is consistent with the reported PGT trend still unclear. We explored the above questions at widely used flux sites in Northern Hemisphere mid-latitudes and found that no significant differences in PPT derived from GPP using different carbon flux partitioning methods. Moreover, fitting methods performed well in grassland, cropland, wetland, and wood savannas compared with evergreen needleleaf forest, deciduous broadleaf forest, and mixed forest. Unexpectedly, we did not find an advancing trend in PPT derived from GPP compared with PGT from SPOT-VGT normalized difference vegetation index (NDVI). Our study suggests that the principle of the fitting method and physiological property of the biome should be taken into account when predicting PPT. More importantly, PGT is not a good proxy of the PPT. Therefore, PPT trends based on VIs should be viewed with caution. In general, this study is meaningful for better understanding photosynthesis and carbon cycling in the context of changing climate.
Keywords	carbon ; climate ; cropland ; deciduous forests ; ecosystems ; grasslands ; gross primary productivity ; latitude ; meteorology ; mixed forests ; phenology ; photosynthesis ; satellites ; wetlands ; wood
Language	English
Dates of publication	2022-0815
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	409905-9
ISSN	0168-1923
ISSN	0168-1923
DOI	10.1016/j.agrformet.2022.109054
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Article: Shift of soil fungal communities under afforestation in Nanliu River Basin, southwest China

Xue, Yuanyuan / Chen, Lijuan / Zhao, Yinjun / Feng, Qi / Li, Changsheng / Wei, Yongping

Journal of environmental management. 2022 Jan. 15, v. 302

2022

Abstract: Although soil fungi play a pivotal role in determining soil ecosystematic feedbacks to afforestation, there remains a big knowledge gap in the effects of afforestation on soil fungal communities, especially at a watershed scale. In this study, the ... ...

Abstract	Although soil fungi play a pivotal role in determining soil ecosystematic feedbacks to afforestation, there remains a big knowledge gap in the effects of afforestation on soil fungal communities, especially at a watershed scale. In this study, the variations of soil fungal diversity and community structures under afforestation were investigated in Nanliu River Basin, where paddy field and dry farmland were converted to eucalyptus plantation at an unprecedented speed. Spatial distance along the upper, middle and lower reaches of the Basin were also considered to analyze the dominant sources of the variations. The results demonstrated that eucalyptus afforestation had little effect on soil fungal diversity but could significantly influence fungal community structures. As paddy field and dry farmland converted to eucalyptus plantation, dominant fungal phylum shifted from Ascomycota to Ascomycota and Basidiomycota. Compared with afforestation from dry farmland, much bigger variation of fungal community structures was found in afforestation from paddy field. In addition, the significant change of fungal community structures exhibited in the upper reaches was from dry farmland, while presented in the middle reaches was from paddy field. However, afforestation comprised a larger source of variation than spatial distance within the soil fungal community structures, and Fusarium, Westerdykella,Zopfiella and Scleroderma were the most sensitive genera affected by afforestation. These results showed that afforestation did not always cause soil fungal diversity change and the heterogeneity of fungal community structures under afforestation was mainly controlled by original land use practices, while spatial distance partly decided the results.
Keywords	Basidiomycota ; Eucalyptus ; Fusarium ; afforestation ; basins ; environmental management ; fungal communities ; land use ; paddies ; soil ; soil fungi ; watersheds ; China
Language	English
Dates of publication	2022-0115
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2021.114130
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Article ; Online: Metagenomics reveals taxon-specific responses of soil nitrogen cycling under different fertilization regimes in heavy metal contaminated soil.

Shi, Xinwei / Tan, Weilan / Tang, Shuting / Ling, Qiujie / Tang, Chijian / Qin, Peiqing / Luo, Shiyu / Zhao, Yinjun / Yu, Fangming / Li, Yi

Journal of environmental management

2023 Volume 345, Page(s) 118766

Abstract: Soil deficiency, cyclic erosion, and heavy metal pollution have led to fertility loss and ecological function decline in mining areas. Fertilization is an important way to rapidly replenish soil nutrients, which have a major influence on the soil ... ...

Abstract	Soil deficiency, cyclic erosion, and heavy metal pollution have led to fertility loss and ecological function decline in mining areas. Fertilization is an important way to rapidly replenish soil nutrients, which have a major influence on the soil nitrogen cycling process, but different fertilization regimes have different impacts on soil properties and microbial functional potentials. Here, metagenomic sequencing was used to investigate the different responses of key functional genes of microbial nitrogen cycling to fertilization regimes and explore the potential effects of soil physicochemical properties on the key functional genes. The results indicated that AC-HH (ammonium chloride-high frequency and concentration) treatment significantly increased the gene abundance of norC (13.40-fold), nirK (5.46-fold), and napA (5.37-fold). U-HH (urea-high frequency and concentration) treatment significantly increased the gene abundance of hao (6.24-fold), pmoA-amoA (4.32-fold) norC (7.00-fold), nosZ (3.69-fold), and nirK (6.88-fold). Functional genes were distributed differently among the 10 dominant phyla. The nifH and nifK genes were distributed only in Proteobacteria. The hao gene was distributed in Gemmatimonadetes, Nitrospirae and Proteobacteria. Fertilization regimes caused changes in functional redundancy in soil, and nirK and nirB, which are involved in denitrification, were present in different genera. Fertilization regimes with high frequency and high concentration were more likely to increase the gene abundance at the genus level. In summary, this study provides insights into the taxon-specific response of soil nitrogen cycling under different fertilization regimes, where changes in fertilization regimes affect microbial nitrogen cycling by altering soil physicochemical properties in a complex dynamic environment.
MeSH term(s)	Soil/chemistry ; Metagenomics ; Soil Microbiology ; Bacteria/genetics ; Fertilization ; Nitrogen
Chemical Substances	Soil ; Nitrogen (N762921K75)
Language	English
Publishing date	2023-08-14
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2023.118766
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