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Article ; Online: Complexity Computer Simulation in the Study of the Overall Playing Method of Campus Football

Zhao Dai

Complexity, Vol

2021 Volume 2021

Abstract: With the mutual exchange and integration of world football, modern football is in an increasingly comprehensive direction. This research mainly discusses complexity computer simulation in the study of the overall play of campus football. Complexity ... ...

Abstract	With the mutual exchange and integration of world football, modern football is in an increasingly comprehensive direction. This research mainly discusses complexity computer simulation in the study of the overall play of campus football. Complexity computer simulation is used to design the background of the simulated football field, and the area is divided according to the size ratio of the actual football field. Then, it uses drawing software to draw the football and player controls. The construction of the knowledge base of this paper is mainly combined with the functional modules of rapid formation and response tactics. In the fast formation function, the required formation can be quickly given through football experience and knowledge rules. In the applied tactics function, for the responsibilities of forwards, midfielders, defenders, and other roles, the tactics implemented are given, including partially coordinated offensive and defensive tactics, personal offensive and defensive tactics, and set-ball tactics. The “holistic play” football tactics studied in this paper use XML files as recording and playback data, which not only greatly reduce the amount of file data but also make the operation of XML files intuitive and simple. XML can not only realize the recording and playback of player and football track but also be used in the function of rapid formation. The coach uses the “holistic play” football tactics simulation to demonstrate the movement route through the image, guide the players in each position to perceive the game scene by observing the movement route, and analyze and judge the tactical coordination of their respective positions. The computer simulation tactical analysis of the precision of the passing and running and the path coefficient of the passing factor is 0.606 and 0.59, respectively. This research helps to provide guidance on the overall playing tactics of football.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Subject code	910
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Development of Support Layers and Their Impact on the Performance of Thin Film Composite Membranes (TFC) for Water Treatment

Qing Zhang / Rui Zhou / Xue Peng / Nan Li / Zhao Dai

Polymers, Vol 15, Iss 3290, p

2023 Volume 3290

Abstract: Thin-film composite (TFC) membranes have gained significant attention as an appealing membrane technology due to their reversible fouling and potential cost-effectiveness. Previous studies have predominantly focused on improving the selective layers to ... ...

Abstract	Thin-film composite (TFC) membranes have gained significant attention as an appealing membrane technology due to their reversible fouling and potential cost-effectiveness. Previous studies have predominantly focused on improving the selective layers to enhance membrane performance. However, the importance of improving the support layers has been increasingly recognized. Therefore, in this review, preparation methods for the support layer, including the traditional phase inversion method and the electrospinning (ES) method, as well as the construction methods for the support layer with a polyamide (PA) layer, are analyzed. Furthermore, the effect of the support layers on the performance of the TFC membrane is presented. This review aims to encourage the exploration of suitable support membranes to enhance the performance of TFC membranes and extend their future applications.
Keywords	substrate ; support layer ; electrospinning ; thin-film composite membrane ; phase inversion ; Organic chemistry ; QD241-441
Language	English
Publishing date	2023-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Multievaluation Strategy for Liujunzi Decoction

Xi-Pei Wu / Yong-Zhao Dai / Ke Nie

Journal of Chemistry, Vol

Fingerprint Characterization, Chemometrics Analysis, Network Pharmacology, and Molecular Docking

2022 Volume 2022

Abstract: Liujunzi decoction (LJZD), a traditional tonic formula for treating “qi” deficiency of the spleen and the syndrome of phlegm dampness, can be used to prevent and treat chemotherapy-induced anorexia (CIA). The chemical constituents of LJZD are rather ... ...

Abstract	Liujunzi decoction (LJZD), a traditional tonic formula for treating “qi” deficiency of the spleen and the syndrome of phlegm dampness, can be used to prevent and treat chemotherapy-induced anorexia (CIA). The chemical constituents of LJZD are rather complex; therefore, it is of great significance to establish an effective and economic quality control method to ensure the quality consistency and stability of LJZD. With one chromatographic condition, 13 common peaks detected at 203 nm were selected to establish a fingerprint similarity model and 7 chemical constituents were identified as ephedrine hydrochloride, liquiritin, hesperidin, ginsenoside Rg1, jujuboside A, 6-gingerol, and atractylenolide III. Ten batches of LJZD were divided into two groups by cluster analysis and principal component analysis (PCA), and four main components (ephedrine hydrochloride, hesperidin, ginsenoside Rg1, and jujuboside A) of LJZD were analyzed. Also, the analysis results were combined with network pharmacology and molecular docking technology to further predict how LJZD could prevent and treat CIA. We found that these four main components of LJZD spontaneously combined with four CIA targets (SRC, PIK3R1, MAPK1, and AKT1). In this study, we established the fingerprint of LJZD for the first time, and through a comprehensive multiassessment method, we also successively analyzed the fingerprint and chemometrics.
Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Research Progress on the Antiemetic Effect of Traditional Chinese Medicine Against Chemotherapy-Induced Nausea and Vomiting

Yao-Zhong Zhao / Yong-Zhao Dai / Ke Nie

Frontiers in Pharmacology, Vol

A Review

2022 Volume 12

Abstract: Chemotherapy-induced nausea and vomiting (CINV), a common side effect in antineoplastic treatment, dramatically decreases the quality of life as well as the compliance of cancer patients. Although numerous antiemetic agents have been used for CINV ... ...

Abstract	Chemotherapy-induced nausea and vomiting (CINV), a common side effect in antineoplastic treatment, dramatically decreases the quality of life as well as the compliance of cancer patients. Although numerous antiemetic agents have been used for CINV treatment, its adverse reactions as well as its inadequate control toward delayed emesis still limit its clinical usage. Traditional Chinese medicine (TCM), with more than 3,000 years of practical history in Asia, has been successfully applied to mitigate chemotherapy-induced side effects. Growing attention is drawn to the antiemetic effect of TCM against CINV due to its promising therapeutic property and higher safety recently. In this review, we summarize the classic antiemetic TCM-based treatment and its mechanisms, so as to provide a theoretical basis for further investigations of TCM against CINV in the future.
Keywords	chemotherapy ; nausea ; vomiting ; traditional Chinese medicine ; review ; Therapeutics. Pharmacology ; RM1-950
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: L-Citrulline Ameliorates Iron Metabolism and Mitochondrial Quality Control via Activating AMPK Pathway in Intestine and Improves Microbiota in Mice with Iron Overload.

Zhao, Dai / Gao, Yuan / Chen, Yiqin / Zhang, Yingsi / Deng, Yian / Niu, Sai / Dai, Hanchuan

Molecular nutrition & food research

2024 Volume 68, Issue 6, Page(s) e2300723

Abstract: Scope: Oxidative stress caused by iron overload tends to result in intestinal mucosal barrier dysfunction and intestinal microbiota imbalance. As a neutral and nonprotein amino acid, L-Citrulline (L-cit) has been implicated in antioxidant and ... ...

Abstract	Scope: Oxidative stress caused by iron overload tends to result in intestinal mucosal barrier dysfunction and intestinal microbiota imbalance. As a neutral and nonprotein amino acid, L-Citrulline (L-cit) has been implicated in antioxidant and mitochondrial amelioration properties. This study investigates whether L-cit can alleviate iron overload-induced intestinal injury and explores the underlying mechanisms. Methods and results: C57BL/6J mice are intraperitoneally injected with iron dextran, then gavaged with different dose of L-cit for 2 weeks. L-cit treatment significantly alleviates intestine pathological injury, oxidative stress, ATP level, and mitochondrial respiratory chain complex activities, accompanied by ameliorating mitochondrial quality control. L-cit-mediated protection is associated with the upregulation of Glutathione Peroxidase 4 (GPX4) expression, inhibition Nuclear Receptor Coactivator 4 (NCOA4)-mediated ferritinophagy and ferroptosis, and improvement of gut microbiota. To investigate the underlying molecular mechanisms, Intestinal Porcine Epithelial Cell line-J2 (IPEC-J2) cells are treated with L-cit or AMP-activated Protein Kinase (AMPK) inhibitor. AMPK signaling has been activated by L-cit. Notably, Compound C abolishes L-cit's protection on intestinal barrier, mitochondrial function, and antioxidative capacity in IPEC-J2 cells. Conclusion: L-cit may restrain ferritinophagy and ferroptosis to regulate iron metabolism, and induce AMPK pathway activation, which contributes to exert antioxidation, ameliorate iron metabolism and mitochondrial quality control, and improve intestinal microbiota. L-cit is a promising therapeutic strategy for iron overload-induced intestinal injury.
MeSH term(s)	Mice ; Animals ; Swine ; AMP-Activated Protein Kinases/metabolism ; Citrulline/metabolism ; Citrulline/pharmacology ; Mice, Inbred C57BL ; Intestines ; Antioxidants/metabolism ; Iron Overload/metabolism ; Microbiota ; Iron/metabolism ; Mitochondria
Chemical Substances	AMP-Activated Protein Kinases (EC 2.7.11.31) ; Citrulline (29VT07BGDA) ; Antioxidants ; Iron (E1UOL152H7)
Language	English
Publishing date	2024-03-01
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2160372-8
ISSN	1613-4133 ; 1613-4125
ISSN (online)	1613-4133
ISSN	1613-4125
DOI	10.1002/mnfr.202300723
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Analysis and Prediction of Electrospun Nanofiber Diameter Based on Artificial Neural Network

Ming Ma / Huchen Zhou / Suhan Gao / Nan Li / Wenjuan Guo / Zhao Dai

Polymers, Vol 15, Iss 2813, p

2023 Volume 2813

Abstract: Electrospinning technology enables the fabrication of electrospun nanofibers with exceptional properties, which are highly influenced by their diameter. This work focuses on the electrospinning of polyacrylonitrile (PAN) to obtain PAN nanofibers under ... ...

Abstract	Electrospinning technology enables the fabrication of electrospun nanofibers with exceptional properties, which are highly influenced by their diameter. This work focuses on the electrospinning of polyacrylonitrile (PAN) to obtain PAN nanofibers under different processing conditions. The morphology and size of the resulting PAN nanofibers were characterized using scanning electron microscopy (SEM), and the corresponding diameter data were measured using Nano Measure 1.2 software. The processing conditions and corresponding nanofiber diameter data were then inputted into an artificial neural network (ANN) to establish the relationship between the electrospinning process parameters (polymer concentration, applied voltage, collecting distance, and solution flow rate), and the diameter of PAN nanofibers. The results indicate that the polymer concentration has the greatest influence on the diameter of PAN nanofibers. The developed neural network prediction model provides guidance for the preparation of PAN nanofibers with specific dimensions.
Keywords	electrostatic spinning ; artificial neural network ; diameter ; prediction ; nanofibers ; Organic chemistry ; QD241-441
Subject code	620
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Progress in application of long non-coding RNA in the diagnosis and treatment of thyroid cancer.

Zhou, Tian / Wang, Li-Kun / Huang, Yu-Xin / Zhao, Dai-Wei

Asian journal of surgery

2022 Volume 45, Issue 10, Page(s) 1971–1972

MeSH term(s)	Gene Expression Regulation, Neoplastic ; Humans ; RNA, Long Noncoding/genetics ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/genetics ; Thyroid Neoplasms/therapy
Chemical Substances	RNA, Long Noncoding
Language	English
Publishing date	2022-04-28
Publishing country	China
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2022.04.039
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Article ; Online: Pharmacological Applications and Action Mechanisms of Phytochemicals as Alternatives to Antibiotics in Pig Production.

Li, Lexing / Sun, Xueyan / Zhao, Dai / Dai, Hanchuan

Frontiers in immunology

2021 Volume 12, Page(s) 798553

Abstract: Antibiotics are widely used for infectious diseases and feed additives for animal health and growth. Antibiotic resistant caused by overuse of antibiotics poses a global health threat. It is urgent to choose safe and environment-friendly alternatives to ... ...

Abstract	Antibiotics are widely used for infectious diseases and feed additives for animal health and growth. Antibiotic resistant caused by overuse of antibiotics poses a global health threat. It is urgent to choose safe and environment-friendly alternatives to antibiotics to promote the ecological sustainable development of the pig industry. Phytochemicals are characterized by little residue, no resistance, and minimal side effects and have been reported to improve animal health and growth performance in pigs, which may become a promising additive in pig production. This paper summarizes the biological functions of recent studies of phytochemicals on growth performance, metabolism, antioxidative capacity, gut microbiota, intestinal mucosa barrier, antiviral, antimicrobial, immunomodulatory, detoxification of mycotoxins, as well as their action mechanisms in pig production. The review may provide the theoretical basis for the application of phytochemicals functioning as alternative antibiotic additives in the pig industry.
MeSH term(s)	Animal Feed ; Animal Husbandry/methods ; Animals ; Anti-Bacterial Agents/adverse effects ; Phytochemicals/pharmacology ; Swine
Chemical Substances	Anti-Bacterial Agents ; Phytochemicals
Language	English
Publishing date	2021-12-09
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2021.798553
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Article: Recurrence risk factors of intravitreal ranibizumab monotherapy in retinopathy of prematurity: a retrospective study at one center.

Wu, Feng-Yue / Yu, Wen-Ting / Zhao, Dai-Xin / Pu, Wei / Zhang, Xue / Gai, Chun-Liu

International journal of ophthalmology

2023 Volume 16, Issue 1, Page(s) 95–101

Abstract: Aim: To identify risk factors of recurrence of this disorder after intravitreal ranibizumab (IVR) monotherapy.: Methods: Totally 33 eyes of 19 patients who underwent initial IVR treatments for type 1 retinopathy of prematurity (ROP) at our center ... ...

Abstract	Aim: To identify risk factors of recurrence of this disorder after intravitreal ranibizumab (IVR) monotherapy. Methods: Totally 33 eyes of 19 patients who underwent initial IVR treatments for type 1 retinopathy of prematurity (ROP) at our center were retrospectively reviewed between April 1, 2016 and December 31, 2017. Patient demographics, the side of ROP, multiple gestations, Apgar scores, zone, stage, plus disease, postmenstrual age at injection, surfactant therapy, blood transfusion therapy, hemorrhage before IVR, hemorrhage after IVR, gestational diabetes mellitus, pregnancy-induced hypertension, anemia, intraventricular hemorrhage, sepsis, respiratory distress syndrome, carbohemia, and congenital heart defects were recorded. Adjusted hazard ratios (HRs) and 95% confidence intervals were determined after adjusting for potential confounders using multivariate proportional Cox regression. Results: Of the 33 eyes, 12 (36.4%) had ROP recurrences 45.3 (5.1, 50.9)mo after initial IVR treatments. The independent risk factors for ROP recurrences were zone (II Conclusion: Two independent risk factors for type 1 ROP recurrence after IVR treatment involving zone I and gestational diabetes mellitus are identified, and the mean uncorrected visual acuity is 0.46 logMAR at 51.0 (44.0, 58.9)mo. The findings of this study are important for follow-up management and for improving the visual function of ROP patients.
Language	English
Publishing date	2023-01-18
Publishing country	China
Document type	Journal Article
ZDB-ID	2663246-9
ISSN	2227-4898 ; 2222-3959
ISSN (online)	2227-4898
ISSN	2222-3959
DOI	10.18240/ijo.2023.01.14
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Article: Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression.

Zhou, Tian / Ma, Ning / Zhang, Yong-Lin / Chen, Xing-Hong / Luo, Xue / Zhang, Mai / Gao, Qing-Jun / Zhao, Dai-Wei

Heliyon

2024 Volume 10, Issue 2, Page(s) e23875

Abstract: Objective: In recent decades, thyroid cancer (TC) has exhibited a rising incidence pattern. Elevated levels of the transcription factor FOXP4 have been strongly linked to the progression of diverse tumors; nevertheless, its specific role in thyroid ... ...

Abstract	Objective: In recent decades, thyroid cancer (TC) has exhibited a rising incidence pattern. Elevated levels of the transcription factor FOXP4 have been strongly linked to the progression of diverse tumors; nevertheless, its specific role in thyroid cancer remains underexplored. The primary objective of this study was to elucidate the functions of FOXP4 and its associated target gene, FBXW7, in the context of thyroid cancer. Methods: FOXP4 and FBXW7 expression levels in TC tissues and cell lines were assessed through immunohistochemistry and RT-qPCR analyses. The functional aspects of FOXP4, including its effects on cell proliferation, migration capabilities, cell cycle regulation, and epithelial-mesenchymal transition (EMT), were investigated. Furthermore, the interaction between FOXP4 and FBXW7 was confirmed using chromatin immunoprecipitation (ChIP) assays. The impact of FBXW7 on FOXP4-mediated cellular phenotypes was subsequently examined. Additionally, the in vivo role of FOXP4 and FBXW7 in tumor growth was elucidated through the establishment of a murine tumor model. Results: Elevated levels of FOXP4 were observed in papillary carcinoma tissues, and patients exhibiting high FBXW7 levels showed a more favorable prognosis. KTC-1 cells displayed a concomitant increase in FOXP4 expression and decrease in FBXW7 expression. FOXP4 overexpression in these cells enhanced cell proliferation, migration capabilities, and EMT. The interaction between the FOXP4 protein and the FBXW7 promoter was confirmed, and the effects of FOXP4 were mitigated upon overexpression of FBXW7. Furthermore, knockdown of FOXP4 led to decelerated growth of transplanted tumors and increased FBXW7 levels within the tumors. Conclusion: The findings of the current study underscore the regulatory role of FOXP4 in the transcription of FBXW7 and establish a clear link between aberrations in FBXW7 expression and the manifestation of malignant phenotypes in highly aggressive TC cells.
Language	English
Publishing date	2024-01-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e23875
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