Article ; Online: The Predictive Effect of Negative Psychological Emotions of Anxiety and Depression on the Poor Prognosis of CHD Patients with Stent Implantation and the Improvement of Clinical Intervention Measures
Computational and Mathematical Methods in Medicine, Vol
2022 Volume 2022
Abstract: Objective. To explore the predictive effect of negative emotions such as anxiety and depression on the poor prognosis of coronary heart disease (CHD) patients with stent implantation and to seek the improvement of clinical intervention measures. Methods. ...
Abstract | Objective. To explore the predictive effect of negative emotions such as anxiety and depression on the poor prognosis of coronary heart disease (CHD) patients with stent implantation and to seek the improvement of clinical intervention measures. Methods. A total of 303 patients with CHD and PCI were recruited from February 2019 to April 2021. The risk factors of CHD such as anxiety and depression, age, sex, smoking and drinking, BMI, hypertension, diabetes, dyslipidemia, and family history of CHD were collected. Meanwhile, clinical data such as laboratory examination, angiography, diseased vessels, and stent types were collected. The patients were followed up for 1 year, and the medical records, hospitalization records, or death records were checked by telephone interview once a month. Major adverse cardiovascular events (MACE) such as emergency and causes, readmission times and causes, new nonfatal myocardial infarction, stent restenosis, heart failure, arrhythmia, and death were recorded. The incidence of anxiety and depression in patients after PCI was counted, and Cox regression was applied to analyze the influence and prediction of anxiety and depression on MACE in patients with CHD stent implantation and improve clinical intervention measures. Results. Compared with those without MACE, anxiety (56.25% vs 30.63%), depression (62.5% vs 22.88%, P<0.01), anxiety combined with depression (46.88% vs 15.50%, P<0.01), and hypertension history (71.8% vs 39.11%, P<0.01) were more common in patients with MACE. Uncorrected Cox proportional hazard regression found that people with anxiety had a higher risk of developing MACE than those without anxiety (HR 3.181, P<0.01). Multiple Cox proportional hazard regression analysis of anxiety showed that anxiety was an independent predictor of cumulative MACE (P<0.01). The risk of developing MACE in patients with anxiety was 3.742 times higher than that in patients without anxiety (P<0.01). Uncorrected Cox hazard regression analysis showed that people with ... |
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Keywords | Computer applications to medicine. Medical informatics ; R858-859.7 |
Subject code | 610 |
Language | English |
Publishing date | 2022-01-01T00:00:00Z |
Publisher | Hindawi Limited |
Document type | Article ; Online |
Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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