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  1. Article: Features of d-vitamin status in young children in the Kazakh population.

    Zhumalina, Akmaral / Kim, Irina / Tusupkaliev, Balash / Zharlykasinova, Mairamkul / Zhekeyeva, Botagoz

    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

    2024  Volume 52, Issue 2, Page(s) 161–170

    Abstract: Objective: Aim: The purpose of the article is to form the parameters of vitamin D status in young children in the ethnic group of Kazakh nationality with the factor of highlighting the necessary recommendations for the prevention of hypovitaminosis D.!## ...

    Abstract Objective: Aim: The purpose of the article is to form the parameters of vitamin D status in young children in the ethnic group of Kazakh nationality with the factor of highlighting the necessary recommendations for the prevention of hypovitaminosis D.
    Patients and methods: Materials and Methods: Methods for the study of the highlighted problem are the diagnosis of young children in the parameter of clinical and anamnestic research, which includes the collection of anamnestic data of children of Kazakh nationality within the framework of the identified data based on a questionnaire of parents, an evaluation component in the child's health factor at the level of his initial state, and laboratory analysis to determine 25(OH)D to identify the content of vitamin D using the method of electrochemiluminescent immunoassay.
    Results: Results: Analysis of vitamin D levels revealed significant differences among age groups. In the 0-28-day group, average vitamin D was 13.35 ng/ml, with 92.8% deficient. In the 1-6-month group, it was 21.47 ng/ml, with 84% deficient. In the over 6-month group, it was 33.58 ng/ml, with 40% sufficient. Formula-fed children had the lowest levels (average 15.21 ng/ml), while breastfed children had insufficiency (average 23.91 ng/ml). Children with vitamin D supplementation averaged 25.9 ng/ml, compared to 19.01 ng/ml without supplementation.
    Conclusion: Conclusions: The results point to a widespread deficiency of vitamin D and offer practical recommendations for its prevention, such as creating a unified system of timely diagnosis, implementing preventive measures in pregnant women and young children, including a balanced diet enriched with vitamin D, staying outdoors in the bright hours of the day.
    MeSH term(s) Child ; Humans ; Female ; Pregnancy ; Child, Preschool ; Vitamins/therapeutic use ; Vitamin D/therapeutic use ; Vitamin D Deficiency ; Breast Feeding ; Surveys and Questionnaires
    Chemical Substances Vitamins ; Vitamin D (1406-16-2)
    Language English
    Publishing date 2024-03-07
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 1388406-2
    ISSN 1426-9686
    ISSN 1426-9686
    DOI 10.36740/Merkur202402104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Retraction Note: The levels of pro- and anti-inflammatory cytokines in premature infants with perinatal infections.

    Zhumalina, Akmaral K / Tusupkaliev, Balash T / Zharlykasinova, Mairamkul B / Zhekeyeva, Botagoz A / Darzhanova, Klara B

    Molecular and cellular biochemistry

    2024  Volume 479, Issue 3, Page(s) 739

    Language English
    Publishing date 2024-02-26
    Publishing country Netherlands
    Document type Retraction of Publication
    ZDB-ID 184833-1
    ISSN 1573-4919 ; 0300-8177
    ISSN (online) 1573-4919
    ISSN 0300-8177
    DOI 10.1007/s11010-024-04972-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The levels of pro- and anti-inflammatory cytokines in premature infants with perinatal infections.

    Zhumalina, Akmaral K / Tusupkaliev, Balash T / Zharlykasinova, Mairamkul B / Zhekeyeva, Botagoz A / Darzhanova, Klara B

    publication RETRACTED

    Molecular and cellular biochemistry

    2021  Volume 477, Issue 2, Page(s) 621–625

    Abstract: Intrauterine infections are an urgent problem of modern neonatology. One of the causes of intrauterine infective foetal lesions is physiological immunosuppression. The purpose of this study is to investigate the cytokine status in newborns infected with ... ...

    Abstract Intrauterine infections are an urgent problem of modern neonatology. One of the causes of intrauterine infective foetal lesions is physiological immunosuppression. The purpose of this study is to investigate the cytokine status in newborns infected with perinatal infections, depending on their body weight. The study examined 145 newborns. Taking into account their body weight, they were divided into 2 groups: main and secondary. The study was conducted in the immunological laboratory of the Medical Centre of Marat Ospanov West Kazakhstan Medical University in the city of Aktobe, with the determination of the level of IgM and IgG to the herpes simplex virus (HSV) types 1, 2, cytomegalovirus (CMV), and chlamydia using the MULTISKANASCENT analyser with the "Chemo" T system. The main results of this study are the predominance of the anti-inflammatory component in both normal weight and underweight infants, which is evidence of the Th-cell-mediated immune response prevalence. The applied value of this study lies in the possibility of applying its results in practice to obtain effective methods to counteract the occurrence and development of intrauterine infections.
    MeSH term(s) Chlamydia Infections/immunology ; Chlamydia Infections/microbiology ; Chlamydia Infections/virology ; Cytokines/immunology ; Female ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/immunology ; Infant, Newborn, Diseases/microbiology ; Infant, Newborn, Diseases/virology ; Infant, Premature/immunology ; Inflammation/immunology ; Inflammation/microbiology ; Inflammation/virology ; Male ; Virus Diseases/immunology ; Virus Diseases/microbiology ; Virus Diseases/virology
    Chemical Substances Cytokines
    Language English
    Publishing date 2021-12-03
    Publishing country Netherlands
    Document type Journal Article ; Retracted Publication
    ZDB-ID 184833-1
    ISSN 1573-4919 ; 0300-8177
    ISSN (online) 1573-4919
    ISSN 0300-8177
    DOI 10.1007/s11010-021-04314-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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