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  1. Article ; Online: Concentration of serum uric acid in patients with Renal Artery Stenosis and Hypertension prEdict Future nephropathy and death: C-RASHEF study.

    Zheng, Bin

    Journal of clinical hypertension (Greenwich, Conn.)

    2023  Volume 25, Issue 4, Page(s) 360–369

    Abstract: Since both serum uric acid (SUA) and renal artery stenosis (RAS) are associated with atherosclerotic events and renal events, it is interesting to investigate whether SUA could predict long-term outcome in patients with RAS. Patients were enrolled from ... ...

    Abstract Since both serum uric acid (SUA) and renal artery stenosis (RAS) are associated with atherosclerotic events and renal events, it is interesting to investigate whether SUA could predict long-term outcome in patients with RAS. Patients were enrolled from inpatients from 2010 to 2014, must be ≥40-year-old. There were 3269 hypertensive patients enrolled, including 325 RAS patients. Endpoints included all-cause death and new or worsening nephropathy (NNP). In analysis for all-cause mortality, associations between SUA and risk of all-cause mortality were an arising curve in total population, a U-shape curve in non-RAS population, and an arising curve in RAS population. When RAS was involved in multivariate analysis, association between SUA and risk of all-cause mortality was still an arising curve in total population. In analysis for NNP, associations between SUA and risk of NNP were a declining curve in total population, not significant in non-RAS population, and a U-shape curve in RAS population. When RAS was involved in multivariate analysis, association between SUA and risk of NNP in total population was no longer significant. Not only association curve of SUA with mortality in non-RAS patients is different from association curve in RAS patients, but also association curve of SUA with NNP in non-RAS patients is different from association curve in RAS patients. The authors conclude that mechanisms of uric acid for mortality and NNP in RAS patients are different from non-RAS patients. In addition to renal vascular obstruction, uric acid is another significant factor for NNP and death in RAS patients.
    MeSH term(s) Humans ; Adult ; Hypertension/complications ; Hypertension/epidemiology ; Uric Acid ; Renal Artery Obstruction/complications ; Renal Artery Obstruction/epidemiology ; Risk Factors ; Kidney
    Chemical Substances Uric Acid (268B43MJ25)
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2077222-1
    ISSN 1751-7176 ; 1524-6175
    ISSN (online) 1751-7176
    ISSN 1524-6175
    DOI 10.1111/jch.14648
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Medical Students' Technology Use for Self-Directed Learning: Contributing and Constraining Factors.

    Zheng, Binbin

    Medical science educator

    2022  Volume 32, Issue 1, Page(s) 149–156

    Abstract: Background: With medical education shifting towards competency-based models, medical students are expected to be self-directed lifelong learners. There is an urgent need to understand what technology students adopt for self-directed learning and what ... ...

    Abstract Background: With medical education shifting towards competency-based models, medical students are expected to be self-directed lifelong learners. There is an urgent need to understand what technology students adopt for self-directed learning and what factors contributed to students' self-initiated technology use.
    Method: This study took place in a midwestern university medical school, which implements a flipped classroom model where students are required to learn all the course materials independently before class. Twenty-six first- and second-year medical students participated in a semi-structured interview about their self-directed learning with technology, and contributing factors towards technology use. A qualitative description methodology using thematic analysis was used to identify key themes from the interview data.
    Results: Medical students reported using four types of technologies for learning video resources, self-assessment tools, management tools, and social media. Three key determinants of students' self-directed technology use were identified, including perceived usefulness, subjective norms, and educational compatibility.
    Conclusions: By probing medical students' self-initiated technology use and its determinants, this study suggested that in a self-directed learning environment, medical students used a variety of third-party resources to facilitate learning and develop self-directed learning skills. This study also provided important practical implications to better support students' productive use of technologies for self-directed learning.
    Language English
    Publishing date 2022-01-27
    Publishing country United States
    Document type Journal Article
    ISSN 2156-8650
    ISSN (online) 2156-8650
    DOI 10.1007/s40670-021-01497-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Impact of releasing period and magnitude on mosquito population in a sterile release model with delay.

    Zheng, Bo

    Journal of mathematical biology

    2022  Volume 85, Issue 2, Page(s) 18

    Abstract: Assuming that there are multiple batches of sterile males reared and released during the maturation period, we derive a switching delay differential model to study the fate of wild females under an impulsive and periodic release of sterile males. For the ...

    Abstract Assuming that there are multiple batches of sterile males reared and released during the maturation period, we derive a switching delay differential model to study the fate of wild females under an impulsive and periodic release of sterile males. For the release magnitude of each batch c, we find two threshold values [Formula: see text] and [Formula: see text], and prove that when [Formula: see text], the model admits exactly two periodic solutions, among which one is asymptotically stable and the other is unstable. The trivial equilibrium, corresponding to the elimination of wild females, is locally asymptotically stable, and it becomes globally asymptotically stable when [Formula: see text]. One key step is to prove that every solution is sandwiched between two "good" solutions.
    MeSH term(s) Animals ; Computer Simulation ; Culicidae ; Female ; Male ; Models, Biological ; Population Dynamics
    Language English
    Publishing date 2022-08-02
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 187101-8
    ISSN 1432-1416 ; 0303-6812
    ISSN (online) 1432-1416
    ISSN 0303-6812
    DOI 10.1007/s00285-022-01785-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Incidence and predictors of chronic pain after inguinal hernia surgery: a systematic review and meta-analysis.

    Chu, Z / Zheng, B / Yan, L

    Hernia : the journal of hernias and abdominal wall surgery

    2024  

    Abstract: Purpose: The mesh is currently the preferred treatment option for hernia repair surgery. Chronic postoperative inguinal pain (CPIP), lasting more than 3 months after surgery, is a complication that significantly impacts patients' quality of life. ... ...

    Abstract Purpose: The mesh is currently the preferred treatment option for hernia repair surgery. Chronic postoperative inguinal pain (CPIP), lasting more than 3 months after surgery, is a complication that significantly impacts patients' quality of life. Currently, there is a lack of evidence-based information describing the incidence and independent predictive factors of chronic pain, posing a serious challenge in clinical practice for devising personalized prevention strategies. Hence, we conducted this systematic review and meta-analysis to investigate the incidence and predictive factors, aiming to provide a reference for developing plans to prevent chronic pain.
    Methods: We conducted a systematic search of PubMed, Cochrane, Embase, and Web of Science, with the retrieval cutoff date set at December 17, 2022. The included studies underwent assessment using the NOS scale, and subgroup analysis for the incidence was carried out based on different regions.
    Results: Ultimately, 18 studies were included, involving 29,466 patients. Meta-analysis showed that the pooled incidence of chronic pain was 17.01% (95%CI 12.78% ~ 21.71%). The incidence was 18.65% (95%CI 13.59% ~ 24.29%) in Europe, 14.70% (95%CI 7.87% ~ 23.17%) in Asia, and 6.04%(95%CI 4.62 ~ 7.64) in North America. Furthermore, We also found that the risk factors for CPIP are younger age [OR = 2.261 (95%CI 1.126 ~ 4.549)], presence of other postoperative complications [OR = 1.849 (95%CI 1.034 ~ 3.305)], hernial sac defect < 3 cm [OR = 1.370 (95%CI 1.012 ~ 1.853)], being female [OR = 1.885 (95%CI 1.024 ~ 3.472)], postoperative pain [OR = 1.553 (95%CI 1.276 ~ 1.889)], preoperative pain [OR = 2.321 (95%CI 1.354 ~ 3.979)], and having a history of ipsilateral inguinal hernia repair [OR = 2.706 (95% CI 1.445 ~ 5.069)].
    Conclusions: The incidence of persistent pain following hernia repair surgery is high in current clinical practice, a concern that should not be overlooked. Stratified assessment tools need to be established for patients experiencing early chronic pain, and personalized follow-up strategies and preventive interventions should be developed for those with potentially high risks. These measures aim to enhance the quality of life for patients after hernia repair.
    Language English
    Publishing date 2024-03-27
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 1388125-5
    ISSN 1248-9204 ; 1265-4906
    ISSN (online) 1248-9204
    ISSN 1265-4906
    DOI 10.1007/s10029-024-02980-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Secondary infections of COVID-19 in schools and the effectiveness of school-based interventions: a systematic review and meta-analysis.

    Zheng, B / Chen, H / Xia, W / Jiang, Y / Zhang, J

    Public health

    2024  Volume 229, Page(s) 42–49

    Abstract: Objectives: This meta-analysis explored secondary infections of SARS-CoV-2 and the effectiveness of non-pharmaceutical interventions (NPIs) in school settings, with the aim of providing a reference to formulate scientific prevention and response ... ...

    Abstract Objectives: This meta-analysis explored secondary infections of SARS-CoV-2 and the effectiveness of non-pharmaceutical interventions (NPIs) in school settings, with the aim of providing a reference to formulate scientific prevention and response strategies for similar major public health emergencies in specific settings.
    Study design: This was a systematic review and meta-analysis.
    Methods: Systematic searches were conducted in PubMed, Web of Science and the Cochrane Library through to 1 August 2022 using the following key search terms: COVID-19, SARS-CoV-2, secondary attack rate, school, transmission, etc. The IVhet model was used for the meta-analysis, and the I
    Results: Thirty-four studies involving 226,727 school contacts and 2216 secondary cases were included in this study. The pooled secondary attack rates (SARs) of close contacts, staff contacts and student contacts were 0.67% (95% confidence interval [CI]: 0.11, 1.56), 0.79% (95% CI: 0.00, 6.72) and 0.50% (95% CI: 0.00, 4.48), respectively. Subgroup analysis suggested that multiple or specific combinations (e.g. the combination of contact restriction and hygiene action) of NPIs appeared to be associated with lower SARs.
    Conclusions: The SAR of SARS-CoV-2 was low in schools. Multiple or specific combinations of prevention strategies appear to mitigate SARS-CoV-2 transmission in school settings. These findings provide a basis for continuous improvement of response strategies to major public health emergencies in the school environment.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; SARS-CoV-2 ; Coinfection ; Emergencies ; Students
    Language English
    Publishing date 2024-02-23
    Publishing country Netherlands
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 427333-3
    ISSN 1476-5616 ; 0033-3506
    ISSN (online) 1476-5616
    ISSN 0033-3506
    DOI 10.1016/j.puhe.2024.01.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Application of CRISPR/Cas systems in the nucleic acid detection of pathogens: a review].

    Li, M / Qin, Z / Yin, K / Zheng, B

    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

    2023  Volume 35, Issue 1, Page(s) 98–103

    Abstract: Rapid, sensitive and specific detection tools are critical for the prevention and control of infectious diseases. ... ...

    Abstract Rapid, sensitive and specific detection tools are critical for the prevention and control of infectious diseases. The
    MeSH term(s) Humans ; CRISPR-Cas Systems/genetics ; Communicable Diseases ; Nucleic Acid Amplification Techniques ; Polymerase Chain Reaction ; Nucleic Acids
    Chemical Substances Nucleic Acids
    Language Chinese
    Publishing date 2023-03-28
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ISSN 1005-6661
    ISSN 1005-6661
    DOI 10.16250/j.32.1374.2022227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Latent Magic

    Zheng, BoYang

    An Investigation into Adversarial Examples Crafted in the Semantic Latent Space

    2023  

    Abstract: Adversarial attacks against Deep Neural Networks(DNN) have been a crutial topic ever since \cite{goodfellow} purposed the vulnerability of DNNs. However, most prior works craft adversarial examples in the pixel space, following the $l_p$ norm constraint. ...

    Abstract Adversarial attacks against Deep Neural Networks(DNN) have been a crutial topic ever since \cite{goodfellow} purposed the vulnerability of DNNs. However, most prior works craft adversarial examples in the pixel space, following the $l_p$ norm constraint. In this paper, we give intuitional explain about why crafting adversarial examples in the latent space is equally efficient and important. We purpose a framework for crafting adversarial examples in semantic latent space based on an pre-trained Variational Auto Encoder from state-of-art Stable Diffusion Model\cite{SDM}. We also show that adversarial examples crafted in the latent space can also achieve a high level of fool rate. However, examples crafted from latent space are often hard to evaluated, as they doesn't follow a certain $l_p$ norm constraint, which is a big challenge for existing researches. To efficiently and accurately evaluate the adversarial examples crafted in the latent space, we purpose \textbf{a novel evaluation matric} based on SSIM\cite{SSIM} loss and fool rate.Additionally, we explain why FID\cite{FID} is not suitable for measuring such adversarial examples. To the best of our knowledge, it's the first evaluation metrics that is specifically designed to evaluate the quality of a adversarial attack. We also investigate the transferability of adversarial examples crafted in the latent space and show that they have superiority over adversarial examples crafted in the pixel space.
    Keywords Computer Science - Machine Learning
    Subject code 006
    Publishing date 2023-05-22
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Expression and clinical importance of a newly discovered alternative splice variant of the gene for acrosin binding protein found in human brain tumors.

    Zheng, Baolong

    Asian biomedicine : research, reviews and news

    2020  Volume 14, Issue 6, Page(s) 243–252

    Abstract: Background: Acrosin binding protein (: Objectives: To determine the expression and clinical impact of a newly discovered splice variant of : Methods: Total RNA was extracted and reverse transcribed from 92 tumor specimens and 3 cell lines. Primers ...

    Abstract Background: Acrosin binding protein (
    Objectives: To determine the expression and clinical impact of a newly discovered splice variant of
    Methods: Total RNA was extracted and reverse transcribed from 92 tumor specimens and 3 cell lines. Primers were designed to determine the expression of the new splice variant in all the samples. Quantitative real-time PCR (qPCR) was conducted for samples positive in reverse transcriptase-PCR. Association of the expression of
    Results: The primers identified a newly discovered splice variant of
    Conclusions: A newly discovered splice variant,
    Language English
    Publishing date 2020-12-31
    Publishing country Thailand
    Document type Journal Article
    ZDB-ID 2583850-7
    ISSN 1875-855X ; 1875-855X
    ISSN (online) 1875-855X
    ISSN 1875-855X
    DOI 10.1515/abm-2020-0033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Gesund bleiben - gesund werden

    Zheng, Buyin

    die Weisheit der chinesischen Heilkunst

    2012  

    Author's details Buyin Zheng
    Keywords Chinesische Medizin
    Subject Traditionelle chinesische Medizin ; TCM
    Subject code 610.951
    Language German
    Size 191 S. : Ill., 22 cm
    Edition 1. Aufl.
    Publisher Schirner
    Publishing place Darmstadt
    Publishing country Germany
    Document type Book
    HBZ-ID HT017446990
    ISBN 978-3-8434-1061-8 ; 3-8434-1061-5
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Achievement Emotions of Medical Students: Do They Predict Self-regulated Learning and Burnout in an Online Learning Environment?

    Wang, Zilu / Zheng, Binbin

    Medical education online

    2023  Volume 28, Issue 1, Page(s) 2226888

    Abstract: Background: Achievement emotions have been proven as important indicators of students' academic performance in traditional classrooms and beyond. In the online learning contexts, previous studies have indicated that achievement emotions would affect ... ...

    Abstract Background: Achievement emotions have been proven as important indicators of students' academic performance in traditional classrooms and beyond. In the online learning contexts, previous studies have indicated that achievement emotions would affect students' adoption of self-regulated learning strategies and further predict their learning outcomes. However, the pathway regarding how different positive and negative achievement emotions might affect students' burnout through self-regulated learning among medical students in online learning environments remains unclear. In this study, the aim is to investigate how achievement emotions and self-regulated learning predict burnout among medical students in online education.
    Methods: This study involved 282 medical students who had attended online courses due to the sudden shift of learning mode caused by the COVID-19 pandemic in 2022. Confirmatory factor analysis was performed to examine the hypothesized factor structure, and structural equation modelling was conducted to test the hypothesized relationships among factors.
    Results: The results of structural equation modelling revealed that medical students' self-efficacy positively predicted their enjoyment (β = .57) and online self-regulated learning (β = .54). Learning-related boredom inhibited students' adoption of online self-regulated learning strategies (β = -.24), and it was positively associated with their burnout (β = .54). Learning-related anxiety was a positive predictor of online self-regulated learning (β = .38).
    Discussions: The results of this study suggest that achievement emotions experienced by medical students had a significant impact on their online self-regulated learning and burnout. Specifically, the experience of learning-related boredom was detrimental to the adoption of self-regulated learning strategies and increased the likelihood of burnout. However, learning-related anxiety, despite being a negative achievement emotion, was positively associated with students' online self-regulated learning. These findings have important implications for online teaching and learning, particularly in the post-pandemic era.
    MeSH term(s) Humans ; Students, Medical/psychology ; Education, Distance ; Pandemics ; Emotions ; Burnout, Professional/epidemiology ; Burnout, Psychological
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2052877-2
    ISSN 1087-2981 ; 1087-2981
    ISSN (online) 1087-2981
    ISSN 1087-2981
    DOI 10.1080/10872981.2023.2226888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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