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  1. Article ; Online: Response to "Comment on 'Sum-frequency vibrational spectroscopy of centrosymmetric molecule at interfaces'" [J. Chem. Phys. 160, 107101 (2024)].

    Zheng, Ren-Hui / Wei, Wen-Mei / Zhang, Shuo-Cang

    The Journal of chemical physics

    2024  Volume 160, Issue 10

    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0177277
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  2. Article ; Online: MiR-659-3p inhibits osteosarcoma progression and metastasis by inhibiting cell proliferation and invasion via targeting SRPK1.

    Gong, Yubao / Wei, Zheng-Ren

    BMC cancer

    2022  Volume 22, Issue 1, Page(s) 934

    Abstract: Objective: Osteosarcoma is the most common primary bone cancer that affects mostly children and young adults. Despite the advances in osteosarcoma treatment, the long-term survival rate of metastatic patients has not significantly improved in the past ... ...

    Abstract Objective: Osteosarcoma is the most common primary bone cancer that affects mostly children and young adults. Despite the advances in osteosarcoma treatment, the long-term survival rate of metastatic patients has not significantly improved in the past few decades, thus demonstrating the need for novel therapeutic targets or methods to improve metastatic osteosarcoma treatment. In this study we aimed to elucidate the role of miR-659-3p and SRPK1 in osteosarcoma.
    Methods: We evaluated miR-659-3p and SRPK1 function in osteosarcoma cell proliferation, migration, and cell cycle progression in vitro by using gain- and loss-of-function strategies. The effect of miR-659-3p in tumor progression and metastasis was determined by in vivo mouse model.
    Results: We revealed that expression of miR-659-3p was significantly downregulated in osteosarcoma compared with normal bone cells and was inversely correlated with serine-arginine protein kinase 1 (SRPK1) expression. We proved that miR-659-3p targets 3' UTR of SRPK1 and negatively regulates SRPK1 expression in osteosarcoma cells via luciferase assay. In vitro studies revealed that gain of miR-659-3p function inhibited osteosarcoma cells growth, migration, and invasion by down-regulating SRPK1 expression. Inversely, inhibiting miR-659-3p in osteosarcoma cells promoted cell growth, migration, and invasion. Cell cycle profile analysis revealed that miR-659-3p inhibited osteosarcoma cells' G1/G0 phase exit by down-regulating SRPK1 expression. By using an in vivo mouse model, we demonstrated that miR-659-3p inhibits osteosarcoma tumor progression and lung metastasis by inhibiting SRPK1 expression and potentially downstream cell proliferation, and epithelial-to-mesenchymal transition genes.
    Conclusions: This study demonstrated that miR-659-3p is a potential therapeutic method and SRPK1 is a potential therapeutic target for osteosarcoma treatment.
    MeSH term(s) 3' Untranslated Regions ; Animals ; Arginine/genetics ; Arginine Kinase/genetics ; Arginine Kinase/metabolism ; Bone Neoplasms/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Mice ; MicroRNAs/genetics ; Neoplastic Processes ; Osteosarcoma/pathology ; Protein Kinases/genetics ; Protein Serine-Threonine Kinases ; Serine/metabolism
    Chemical Substances 3' Untranslated Regions ; MicroRNAs ; Serine (452VLY9402) ; Arginine (94ZLA3W45F) ; Protein Kinases (EC 2.7.-) ; Protein Serine-Threonine Kinases (EC 2.7.11.1) ; Arginine Kinase (EC 2.7.3.3)
    Language English
    Publishing date 2022-08-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-022-10029-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sum-frequency vibrational spectroscopy of methanol at interfaces due to Fermi resonance.

    Zheng, Ren-Hui / Wei, Wen-Mei

    Physical chemistry chemical physics : PCCP

    2022  Volume 24, Issue 44, Page(s) 27204–27211

    Abstract: Sum-frequency nonlinear spectroscopy is a powerful tool in investigating physical and chemical properties at gas/liquid, gas/solid, liquid/liquid and liquid/solid interfaces. Fermi resonance is a well-documented anharmonic phenomenon related to molecular ...

    Abstract Sum-frequency nonlinear spectroscopy is a powerful tool in investigating physical and chemical properties at gas/liquid, gas/solid, liquid/liquid and liquid/solid interfaces. Fermi resonance is a well-documented anharmonic phenomenon related to molecular vibrational coupling and the energy transfer phenomenon that exists within and between molecules. Such a phenomenon is widely used in the fields of materials, biology and chemistry. Combining density functional theory and molecular dynamics simulation, we present a method of studying sum-frequency vibrational spectroscopy for the CH
    Language English
    Publishing date 2022-11-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d2cp01808j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effects of oral calcium on reproduction and postpartum health in cattle: a meta-analysis and quality assessment.

    Ma, Zheng-Ren / Ma, Ling-Li / Zhao, Fei / Bo, Yan

    Frontiers in veterinary science

    2024  Volume 11, Page(s) 1357640

    Abstract: Postpartum blood calcium (Ca) concentration is related to the reproduction and health of cattle. Oral calcium supplements were given to dairy cows after calving to increase blood Ca concentration and reduce the risk of hypocalcemia. However, studies have ...

    Abstract Postpartum blood calcium (Ca) concentration is related to the reproduction and health of cattle. Oral calcium supplements were given to dairy cows after calving to increase blood Ca concentration and reduce the risk of hypocalcemia. However, studies have shown that oral Ca has different effects in preventing disease. The purposes of this study were (i) to conduct a meta-analysis to evaluate the expected effect of oral Ca on incidence of calving-related diseases, pregnancy risk and milk yield in dairy cows, and (ii) to make a quality assessment of these related studies. In total, 22 eligible studies were included in this review. Meta-analysis showed that oral Ca could significantly reduce the incidence of hypocalcemia (clinical hypocalcemia: relative risk (RR) = 0.67, 95% confidence interval (CI) = [0.52, 0.87]; subclinical hypocalcemia: RR = 0.81, CI = [0.72, 0.91]), and incidence of retained placenta (RR = 0.77, CI = [0.62, 0.95]), improved blood Ca concentrations: mean difference (MD) = 0.08; 95% CI = [0.04, 0.11]. For other results, the meta-analysis revealed a lack of evidence of the correlation between oral Ca and serum magnesium (Mg) / phosphorus (P) concentration (Mg: MD = -0.04; 95% CI = [-0.10, 0.02]; P: MD = 0.05; 95% CI = [-0.10, 0.21]) or incidence of other calving-related disorders (metritis: RR = 1.06, CI = [0.94, 1.19]; ketosis: RR = 1.04, CI = [0.91, 1.18]; mastitis: RR = 1.02, CI = [0.86, 1.21]; displacement of the abomasum: RR = 0.81, CI = [0.57, 1.16]) or pregnancy risk (pregnancy risk at first service: RR = 0.99, CI = [0.94, 1.05]; overall pregnancy rate: RR = 1.03, CI = [0.98, 1.08]) or milk yield (MD = 0.44; 95% CI = [-0.24, 1.13]). The distribution of the funnel plot formed by the included studies was symmetrical, and the Egger's test had a
    Language English
    Publishing date 2024-04-10
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2024.1357640
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  5. Article ; Online: Sum-frequency vibrational spectroscopy of centrosymmetric molecule at interfaces.

    Zheng, Ren-Hui / Wei, Wen-Mei / Zhang, Shuo-Cang

    The Journal of chemical physics

    2023  Volume 158, Issue 7, Page(s) 74701

    Abstract: The centrosymmetric benzene molecule has zero first-order electric dipole hyperpolarizability, which results in no sum-frequency vibrational spectroscopy (SFVS) signal at interfaces, but it shows very strong SFVS experimentally. We perform a theoretical ... ...

    Abstract The centrosymmetric benzene molecule has zero first-order electric dipole hyperpolarizability, which results in no sum-frequency vibrational spectroscopy (SFVS) signal at interfaces, but it shows very strong SFVS experimentally. We perform a theoretical study on its SFVS, which is in good agreement with the experimental results. Its strong SFVS mainly comes from the interfacial electric quadrupole hyperpolarizability rather than the symmetry-breaking electric dipole, bulk electric quadrupole, and interfacial and bulk magnetic dipole hyperpolarizabilities, which provides a novel and completely unconventional point of view.
    Language English
    Publishing date 2023-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0139895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Identification of PSMD14 as a potential novel prognosis biomarker and therapeutic target for osteosarcoma.

    Gong, Yubao / Wei, Zheng-Ren

    Cancer reports (Hoboken, N.J.)

    2021  Volume 5, Issue 7, Page(s) e1522

    Abstract: Background: Osteosarcoma is the most common primary bone tumor. The survival rate of osteosarcoma patients has not significantly increased in the past decades. Uncovering the mechanisms of malignancy, progression, and metastasis will shed light on the ... ...

    Abstract Background: Osteosarcoma is the most common primary bone tumor. The survival rate of osteosarcoma patients has not significantly increased in the past decades. Uncovering the mechanisms of malignancy, progression, and metastasis will shed light on the development of new therapeutic targets and treatment for osteosarcoma.
    Aim: The aim of this study is to identify potential osteosarcoma biomarker and/or therapeutic targets by using integrated bioinformatics analysis.
    Methods and results: We utilized existing gene expression datasets to identify differential expressed genes (DEGs) that could serve as osteosarcoma biomarkers or even as therapeutic targets. We found 48 DEGs were overlapped in three datasets. Among these 48 DEGs, PSMD14 was on the top of the up-regulated gene list. We further found that higher PSMD14 expression was correlated with higher risk group (younger age group, ≤20.83 years of age), metastasis within 5 years and higher grade of tumor. Higher PSMD14 expression in osteosarcoma had positive correlation with higher infiltration of CD8+ T cells, neutrophils and myeloid dendritic cells. Kaplan-Myer survival data further revealed that higher expression of PSMD14 predicted significantly worse prognosis (p = .013). Gene set enrichment analysis was further performed for the DEGs related to PSMD14 in osteosarcoma. We found that lower PSMD14 expression group had more immune responses such as interferon γ, α responses, inflammation response etc. However, the higher PSMD14 expression group had more cell proliferation-related biological processes, such as G2M checkpoints and Myc targets. Through establishing protein-protein interaction networks using PSMD14 related DEGs, we identified 10 hub genes that were all ribosomal proteins. These hub genes may play roles in osteosarcoma tumorigenesis, progression and/or metastasis.
    Conclusion: We identified PSMD14 gene as a possible osteosarcoma biomarker, and/or a possible therapeutic target.
    MeSH term(s) Bone Neoplasms/genetics ; Bone Neoplasms/therapy ; Gene Expression Profiling/methods ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Osteosarcoma/diagnosis ; Osteosarcoma/genetics ; Osteosarcoma/therapy ; Prognosis ; Proteasome Endopeptidase Complex/genetics ; Proteasome Endopeptidase Complex/metabolism ; Trans-Activators/genetics ; Trans-Activators/metabolism ; Young Adult
    Chemical Substances PSMD14 protein, human ; Trans-Activators ; Proteasome Endopeptidase Complex (EC 3.4.25.1)
    Language English
    Publishing date 2021-08-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2573-8348
    ISSN (online) 2573-8348
    DOI 10.1002/cnr2.1522
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  7. Article ; Online: Anomalous Hall effect in Nd-doped Bi

    Chen, Lei / Zhao, Weiyao / Xing, Kaijian / You, Mengyun / Wang, Xiaolin / Zheng, Ren-Kui

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 3, Page(s) 2638–2645

    Abstract: Topological insulators are emerging materials with insulating bulk and symmetry protected nontrivial surface states. One of the most fascinating transport behaviors in a topological insulator is the quantum anomalous Hall effect, which has been observed ... ...

    Abstract Topological insulators are emerging materials with insulating bulk and symmetry protected nontrivial surface states. One of the most fascinating transport behaviors in a topological insulator is the quantum anomalous Hall effect, which has been observed in magnetic-topological-insulator-based devices. In this work, we report successful doping of rare-earth element Nd into Bi
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp05850f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: 

    Wu, Tian-Rou / Xu, Jian / An, Ming-Tai / Yu, Jiang-Hong / Liu, Feng / Chen, Zheng-Ren

    PhytoKeys

    2024  Volume 237, Page(s) 37–49

    Abstract: ... ...

    Abstract Hypericumliboense
    Language English
    Publishing date 2024-01-12
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2579891-1
    ISSN 1314-2003 ; 1314-2011
    ISSN (online) 1314-2003
    ISSN 1314-2011
    DOI 10.3897/phytokeys.237.110482
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ultrasound-assisted dispersive liquid-liquid microextraction coupled with field-amplified capillary electrophoresis for sensitive and quantitative determination of fluoxetine and norfluoxetine enantiomers in biological fluids.

    Wang, Zheng Ren / Hsieh, Ming Mu

    Analytical and bioanalytical chemistry

    2020  Volume 412, Issue 21, Page(s) 5113–5123

    Abstract: A rapid, simple, and sensitive technique for the quantitative detection of fluoxetine and norfluoxetine enantiomers in biological fluids was developed based on the combination of field-amplified sample stacking (FASS)-related capillary electrophoresis ( ... ...

    Abstract A rapid, simple, and sensitive technique for the quantitative detection of fluoxetine and norfluoxetine enantiomers in biological fluids was developed based on the combination of field-amplified sample stacking (FASS)-related capillary electrophoresis (CE) with ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME). The extraction efficiency of UA-DLLME was strongly related to extraction time, salt concentration, type of extraction and dispersion solvents, and volume of extraction and dispersion solvents. The extracted fluoxetine and norfluoxetine enantiomers in a mixture of 50% methanol and 50% deionized water were efficiently stacked using FASS and then separated using cyclodextrin-modified CE. Under optimal conditions of FASS (chiral selector, 3 mM trimethyl-β-cyclodextrin; and background electrolyte, 100 mM phosphate buffer) and UA-DLLME (extraction solvent, 200 μL of acetone; and dispersed solvent, 50 μL of C
    MeSH term(s) Body Fluids/chemistry ; Electrophoresis, Capillary/methods ; Fluoxetine/analogs & derivatives ; Fluoxetine/analysis ; Fluoxetine/blood ; Fluoxetine/urine ; Humans ; Limit of Detection ; Liquid Phase Microextraction/methods ; Serotonin Uptake Inhibitors/analysis ; Serotonin Uptake Inhibitors/blood ; Serotonin Uptake Inhibitors/urine ; Sonication ; Spectrophotometry, Ultraviolet/methods ; Stereoisomerism
    Chemical Substances Serotonin Uptake Inhibitors ; Fluoxetine (01K63SUP8D) ; norfluoxetine (K8D70XE2F4)
    Language English
    Publishing date 2020-03-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 201093-8
    ISSN 1618-2650 ; 0016-1152 ; 0372-7920
    ISSN (online) 1618-2650
    ISSN 0016-1152 ; 0372-7920
    DOI 10.1007/s00216-020-02441-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Z 4' 69/97: Show issues
    Archiv 3: Show issues
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  10. Article ; Online: The complete chloroplast genome of two related fig species

    Fungjanthuek, Jenjira / Zhang, Zheng-Ren / Peng, Yan-Qiong / Gao, Jie

    Mitochondrial DNA. Part B, Resources

    2022  Volume 7, Issue 1, Page(s) 236–238

    Abstract: ... ...

    Abstract The
    Language English
    Publishing date 2022-01-24
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2021.2024462
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