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  1. Article ; Online: Effectiveness Analysis of English Newspaper Reading Teaching Based on Deep Learning from the Perspective of Online and Offline Hybrid Teaching

    Zheng Zeng / Xi Wang

    Computational and Mathematical Methods in Medicine, Vol

    2022  Volume 2022

    Abstract: In recent years, China’s higher education has developed rapidly, and the overall English proficiency of college students has improved significantly. In order to improve the English proficiency of students in higher education, English newspaper reading ... ...

    Abstract In recent years, China’s higher education has developed rapidly, and the overall English proficiency of college students has improved significantly. In order to improve the English proficiency of students in higher education, English newspaper reading courses are offered, many of which are elective courses. Reading English newspapers in English can help college students improve their overall English proficiency and benefit them in their future lives. Reading English newspapers can improve students’ English in many ways as part of college English teaching activities. For example, it helps students to accumulate common and authentic words and phrases, improve their English reading efficiency and level, and gain a broader perspective. This paper examines the role of English newspaper reading in college English teaching, proposes an effective analysis method of teaching English newspaper reading based on deep learning from the perspective of online and offline hybrid teaching, and tests the effectiveness of the model. Finally, the specific characteristics of English newspapers are combined to propose suggestions for improving the effectiveness of English teaching activities for college students.
    Keywords Computer applications to medicine. Medical informatics ; R858-859.7
    Subject code 420
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: [Clinicopathological Features of Intrathyroid Thymic Carcinoma].

    Zheng, Zeng Guang / Sun, Wen Yong

    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

    2021  Volume 43, Issue 1, Page(s) 42–46

    Abstract: Objective To investigate the clinicopathological features,immunohistochemical characteristics,diagnosis,treatment and prognosis of intrathyroid thymic carcinoma.Methods Clinical data of 7 patients with intrathyroid thymic carcinoma were retrospectively ... ...

    Abstract Objective To investigate the clinicopathological features,immunohistochemical characteristics,diagnosis,treatment and prognosis of intrathyroid thymic carcinoma.Methods Clinical data of 7 patients with intrathyroid thymic carcinoma were retrospectively reviewed.Histological examination and immunohistochemical staining were performed on the surgically resected tumors.The infection of Epstein-Barr virus(EBV)was detected by EBER in situ hybridization.Results The 7 patients included 5 males and 2 females.The age ranged from 40 to 71 years,with a median of 54 years.The tumors were located in the thyroid gland,with the maximum diameter ranging from 2.2 cm to 6.0 cm and the average maximum diameter of(4.0±1.2)cm.All the patients underwent thyroid gland resection and local lymph node dissection.After operation,all the cases were treated with radiotherapy and five of them additionally received chemotherapy.Six patients were followed up for 10-163 months,all of whom were still alive,including 2 patients with recurrence in situ,1 patient with homolateral cervical lymph node metastasis and the rest with no recurrence or metastasis.CK-pan,P63,CD5 and CD117 were expressed in all the cases,while TTF-1,TG,CT and PAX8 were negative.One case of them expressed SYN and CgA.Ki-67 proliferation index ranged from 10% to 90%.EBER in situ hybridization showed negative results in all 7 cases.Conclusions Intrathyroid thymic carcinoma is a relatively low-grade malignant tumor.The combination of immunohistochemical CD5,CD117 and monoclonal PAX8 is helpful in the diagnosis and differential diagnosis of intrathyroid thymic carcinoma.EBV may not be involved in the development of intrathyroid thymic carcinoma.Thyroid gland resection plus central lymph node dissection is an important treatment measure for intrathyroid thymic carcinoma.For patients with regional lymph node metastasis and obvious peripheral tissue invasion,postoperative radiotherapy with/without chemotherapy can effectively delay the disease progression.
    MeSH term(s) Child, Preschool ; Epstein-Barr Virus Infections ; Female ; Herpesvirus 4, Human ; Humans ; Male ; Neoplasm Recurrence, Local ; Retrospective Studies ; Thymoma ; Thymus Neoplasms/therapy
    Language Chinese
    Publishing date 2021-02-25
    Publishing country China
    Document type Journal Article
    ZDB-ID 604853-5
    ISSN 1000-503X
    ISSN 1000-503X
    DOI 10.3881/j.issn.1000-503X.12609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Robust Gaze Estimation Approach via Exploring Relevant Electrooculogram Features and Optimal Electrodes Placements

    Zheng Zeng / Linkai Tao / Hangyu Zhu / Yunfeng Zhu / Long Meng / Jiahao Fan / Chen Chen / Wei Chen

    IEEE Journal of Translational Engineering in Health and Medicine, Vol 12, Pp 56-

    2024  Volume 65

    Abstract: Gaze estimation, as a technique that reflects individual attention, can be used for disability assistance and assisting physicians in diagnosing diseases such as autism spectrum disorder (ASD), Parkinson’s disease, and attention deficit hyperactivity ... ...

    Abstract Gaze estimation, as a technique that reflects individual attention, can be used for disability assistance and assisting physicians in diagnosing diseases such as autism spectrum disorder (ASD), Parkinson’s disease, and attention deficit hyperactivity disorder (ADHD). Various techniques have been proposed for gaze estimation and achieved high resolution. Among these approaches, electrooculography (EOG)-based gaze estimation, as an economical and effective method, offers a promising solution for practical applications. Objective: In this paper, we systematically investigated the possible EOG electrode locations which are spatially distributed around the orbital cavity. Afterward, quantities of informative features to characterize physiological information of eye movement from the temporal-spectral domain are extracted from the seven differential channels. Methods and procedures: To select the optimum channels and relevant features, and eliminate irrelevant information, a heuristical search algorithm (i.e., forward stepwise strategy) is applied. Subsequently, a comparative analysis of the impacts of electrode placement and feature contributions on gaze estimation is evaluated via 6 classic models with 18 subjects. Results: Experimental results showed that the promising performance was achieved both in the Mean Absolute Error (MAE) and Root Mean Square Error (RMSE) within a wide gaze that ranges from −50° to +50°. The MAE and RMSE can be improved to 2.80° and 3.74° ultimately, while only using 10 features extracted from 2 channels. Compared with the prevailing EOG-based techniques, the performance improvement of MAE and RMSE range from 0.70° to 5.48° and 0.66° to 5.42°, respectively. Conclusion: We proposed a robust EOG-based gaze estimation approach by systematically investigating the optimal channel/feature combination. The experimental results indicated not only the superiority of the proposed ...
    Keywords Channel selection ; electrooculography (EOG) ; feature selection ; gaze estimation ; saccade ; Computer applications to medicine. Medical informatics ; R858-859.7 ; Medical technology ; R855-855.5
    Subject code 004
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher IEEE
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Buckling Behavior of Loosely Fitted Formed-In-Place Pipe Liner in Circular Host Pipe under External Pressure

    Zheng Zeng / Xuefeng Yan / Weigang Xiang / Yahong Zhao / Samuel T. Ariaratnam

    Applied Sciences, Vol 13, Iss 679, p

    2023  Volume 679

    Abstract: The formed-in-place pipe (FIPP) is a trenchless technology used for pipeline rehabilitation. It is a folded PVC pipe that expands through thermoforming to fit tightly inside the host pipe. However, the deficiencies during the construction of FIPP liners ... ...

    Abstract The formed-in-place pipe (FIPP) is a trenchless technology used for pipeline rehabilitation. It is a folded PVC pipe that expands through thermoforming to fit tightly inside the host pipe. However, the deficiencies during the construction of FIPP liners such as insufficient inflation, pipe misalignment and initial deformation will lead to elliptical deformation of the FIPP liner, which affects the load-bearing performance of the liner and makes it susceptible to buckling failure. In this paper, the buckling behavior of loosely fitted FIPP liners under uniform external pressure was investigated by the external pressure resistance test and finite element model. The pre- and post-buckling equilibrium paths verified the finite element model. The results indicated that the value of the dimension ratio will significantly reduce the critical buckling pressure. With the increasing value of liner major axis ratio to host pipe, the reduction effect on the critical buckling pressure caused by the increase in the ovality will diminish. Different values of liner major axis ratio to host pipe and ovality changed the range of the detached portion, which affected the critical buckling pressure. The parametric studies modified the design model from ASTM F1216, which was established to predict the critical buckling pressure of a loosely fitted FIPP liner and reduced the average difference rate from 23.43% to 5.52%.
    Keywords FIPP ; buckling ; ovality ; FEM ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 621
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Mechanism of dexmedetomidine protection against cisplatin induced acute kidney injury in rats.

    Zheng, Zeng-Lu / Ma, Jun-Wei / Luo, Yi / Liang, Gui-Jin / Lei, Shi-Jie / Yan, Ke-Jin / Meng, Hai-Bing / Liu, Xiu-Juan

    Renal failure

    2024  Volume 46, Issue 1, Page(s) 2337287

    Abstract: Objective: This study explored the molecular mechanisms by which dexmedetomidine (Dex) alleviates cisplatin (CP)-induced acute kidney injury (AKI) in rats.: Methods: CP-induced AKI models were established, and Dex was intraperitoneally injected at ... ...

    Abstract Objective: This study explored the molecular mechanisms by which dexmedetomidine (Dex) alleviates cisplatin (CP)-induced acute kidney injury (AKI) in rats.
    Methods: CP-induced AKI models were established, and Dex was intraperitoneally injected at different concentrations into rats in the model groups. Subsequently, rats were assigned to the control, CP, CP + Dex 10 μg/kg, and CP + Dex 25 μg/kg groups. After weighing the kidneys of the rats, the kidney arterial resistive index was calculated, and CP-induced AKI was evaluated. In addition, four serum biochemical indices were measured: histopathological damage in rat kidneys was detected; levels of inflammatory factors, interleukin (IL)-1β, IL-18, IL-6, and tumor necrosis factor alpha, in kidney tissue homogenate of rats were assessed through enzyme-linked immunosorbent assay (ELISA); and levels of NLRP-3, caspase-1, cleaved caspase-1, gasdermin D (GSDMD), and GSDMD-N in kidney tissues of rats were determined
    Results: Dex treatment reduced nephromegaly and serum clinical marker upregulation caused by CP-induced AKI. In addition, hematoxylin and eosin staining revealed that Dex treatment relieved CP-induced kidney tissue injury in AKI rats. ELISA analyses demonstrated that Dex treatment reduced the upregulated levels of proinflammatory cytokines in the kidney tissue of AKI rats induced by CP, thereby alleviating kidney tissue injury. Western blotting indicated that Dex alleviated CP-induced AKI by inhibiting pyroptosis mediated by NLRP-3 and caspase-1.
    Conclusion: Dex protected rats from CP-induced AKI, and the mechanism may be related to NLRP-3/Caspase-1-mediated pyroptosis.
    MeSH term(s) Rats ; Animals ; Dexmedetomidine/adverse effects ; Cisplatin/toxicity ; Acute Kidney Injury/chemically induced ; Acute Kidney Injury/prevention & control ; Acute Kidney Injury/pathology ; Kidney/pathology ; Interleukin-1beta ; Caspases/adverse effects
    Chemical Substances Dexmedetomidine (67VB76HONO) ; Cisplatin (Q20Q21Q62J) ; Interleukin-1beta ; Caspases (EC 3.4.22.-)
    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 632949-4
    ISSN 1525-6049 ; 0886-022X
    ISSN (online) 1525-6049
    ISSN 0886-022X
    DOI 10.1080/0886022X.2024.2337287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cadmium Uptake, In Vivo Metastasis and Subcellular Environmental Response of Five Wetland Plants Using DFT Method

    Zheng Zeng / Wei-Ge Luo / Fa-Cheng Yi / Zhe Wang

    Sustainability, Vol 13, Iss 7872, p

    2021  Volume 7872

    Abstract: The main purpose of this study is to analyze whether Cd 2+ affects the absorption of Ca 2+ and Fe 2+ by the roots of five wetland plants and the toxic mechanism of cadmium on the subcellular structure. Five wetland plant samples were collected from the ... ...

    Abstract The main purpose of this study is to analyze whether Cd 2+ affects the absorption of Ca 2+ and Fe 2+ by the roots of five wetland plants and the toxic mechanism of cadmium on the subcellular structure. Five wetland plant samples were collected from the constructed wetland in the upper reaches of the Yangtze River. Based on the experiment and density function theory (DFT), we measured the Cd 2+ content in the root, stem, and leaf, the morphological dimensions of plants, and in the subcellular structure the electronic activity of Cd compound was calculated to describe the stability and activity of the products. In general, Zephyranthes candida , Cynodon dactylon, Arundo donax , and Pontederia cordata have distinct cadmium uptake characteristics, while Phragmites communis does not. The results indicated tolerance to cadmium in all but Phragmites communis, which was due to cadmium distribution through the process of transpiration and a mechanical interception. The simulation results showed that Cd 2+ imposed no obvious inhibition on the absorption of Ca 2+ and Fe 2+ in plants, as the energy barrier of the process is about 1–3 eV. Cd 2+ could improve the amount of pyruvate and glucose by 30% via spd orbital hybridization, making them more chemically reactive. At the same time, Cd 2+ could replace Mg 2+ in chlorophyll through a copper substitution reaction, making the electron energy of chlorophyll more concentrated. As a result, the valence-band electron at −40 eV was vacant. In conclusion, we determined that Cd 2+ has no obvious inhibitory effect on Ca 2+ and Fe 2+ in root absorption and that Cd 2+ could affect the properties of compounds of the subcellular structure and thus produce physiological toxicity.
    Keywords wetland plants ; density functional theory (DFT) ; cadmium enrichment factor ; cadmium transport coefficient ; subcellular structure ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 333
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Water Pollution and Its Causes in the Tuojiang River Basin, China

    Zheng Zeng / Wei-Ge Luo / Zhe Wang / Fa-Cheng Yi

    Sustainability, Vol 13, Iss 2, p

    An Artificial Neural Network Analysis

    2021  Volume 792

    Abstract: This work aimed to assess the water quality of the Tuojiang River Basin in recent years to provide a better understanding of its current pollution situation, and the potential pollution risks and causes. Water quality parameters such as dissolved oxygen ( ...

    Abstract This work aimed to assess the water quality of the Tuojiang River Basin in recent years to provide a better understanding of its current pollution situation, and the potential pollution risks and causes. Water quality parameters such as dissolved oxygen (DO), ammonia–nitrogen (NH 3 -N), total phosphorus (TP), the permanganate index (CODMn), five-day biochemical oxygen demand (BOD5), pH, and concentrations of various heavy metals were measured in the Tuojiang River, according to the national standards of the People’s Republic of China. Samples were collected between 2012 to 2018 at 11 national monitoring sites in the Tuojiang River Basin. The overall water pollution situation was evaluated with back propagation artificial neural network (BP-ANN) analysis. The pollution causes were analyzed considering both industrial wastewater discharge in the upper reaches and the current pollution situation. We found potential risks of excessive NH 3 -N, TP, Cd, Hg, and Pb concentrations in the Tuojiang River Basin. Moreover, corresponding water pollution control suggestions were given.
    Keywords Tuojiang River ; water pollution ; heavy metal pollution ; BP-ANN evaluation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 333 ; 550
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Elevated pretreatment squamous cell Carcinoma Antigen indicates unfavorable treatment outcomes in cervical cancer patients receiving definitive radiotherapy

    Dingchao Liu / Weiping Wang / Zheng Zeng / Xiaoliang Liu / Yuncan Zhou / Chen Wang / Xiaoyan Li / Ke Hu

    Precision Radiation Oncology, Vol 7, Iss 3, Pp 173-

    2023  Volume 180

    Abstract: Abstract Objective To investigate the prognostic value of pretreatment squamous cell carcinoma antigen (SCC Ag) levels for treatment failure prediction in patients with cervical cancer. Methods A quantity of 985 patients satisfying the eligibility ... ...

    Abstract Abstract Objective To investigate the prognostic value of pretreatment squamous cell carcinoma antigen (SCC Ag) levels for treatment failure prediction in patients with cervical cancer. Methods A quantity of 985 patients satisfying the eligibility criteria were included, with a median follow‐up duration of 63.7 months. The optimal cutoff value for pretreatment SCC Ag levels was verified by the receiver operating characteristic (ROC) curve. Five‐year disease‐free survival (DFS), overall survival (OS), and local control (LC) rates were evaluated utilizing the Kaplan‐Meier method. Log‐rank test and Cox proportional hazards model was implemented to recognize independent prognostic predictors. Results The optimal pretreatment SCC Ag cutoff value was 8.85 ng/mL. Patients with pretreatment SCC Ag levels ≥ 8.85 ng/mL presented significantly inferior 5‐year DFS (63.8% vs. 81.8%), OS (71.7% vs. 88.7%), and LC (80.5% vs. 91.0%) compared to those with levels < 8.85 ng/mL (all p < 0.001). The results of the multivariate analysis indicated that the pretreatment SCC Ag level was an independent predictor of treatment failure (HR,1.772; 95% CI, 1.366 to 2.299; p < 0.001). Conclusion Pretreatment SCC Ag is an effective prognostic factor in patients with cervical cancer undergoing definitive radiotherapy, with a ROC‐identified cutoff value of 8.85 ng/mL and elevated SCC Ag indicates unfavorable outcomes.
    Keywords cervical cancer ; radiotherapy ; squamous cell carcinoma antigen ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282
    Subject code 616 ; 610
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Deprivation of Sexual Reproduction during Garlic Domestication and Crop Evolution

    Einat Shemesh-Mayer / Adi Faigenboim / Amir Sherman / Song Gao / Zheng Zeng / Touming Liu / Rina Kamenetsky-Goldstein

    International Journal of Molecular Sciences, Vol 24, Iss 23, p

    2023  Volume 16777

    Abstract: Garlic, originating in the mountains of Central Asia, has undergone domestication and subsequent widespread introduction to diverse regions. Human selection for adaptation to various climates has resulted in the development of numerous garlic varieties, ... ...

    Abstract Garlic, originating in the mountains of Central Asia, has undergone domestication and subsequent widespread introduction to diverse regions. Human selection for adaptation to various climates has resulted in the development of numerous garlic varieties, each characterized by specific morphological and physiological traits. However, this process has led to a loss of fertility and seed production in garlic crops. In this study, we conducted morpho-physiological and transcriptome analyses, along with whole-genome resequencing of 41 garlic accessions from different regions, in order to assess the variations in reproductive traits among garlic populations. Our findings indicate that the evolution of garlic crops was associated with mutations in genes related to vernalization and the circadian clock. The decline in sexual reproduction is not solely attributed to a few mutations in specific genes, but is correlated with extensive alterations in the genetic regulation of the annual cycle, stress adaptations, and environmental requirements. The regulation of flowering ability, stress response, and metabolism occurs at both the genetic and transcriptional levels. We conclude that the migration and evolution of garlic crops involve substantial and diverse changes across the entire genome landscape. The construction of a garlic pan-genome, encompassing genetic diversity from various garlic populations, will provide further insights for research into and the improvement of garlic crops.
    Keywords Allium sativum ; flowering ; genome ; transcriptome ; gene expression ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 580
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Histopathological findings of nucleus pulposus in lumbar brucellar spondylodiscitis

    Yao zhang / Qiang Zhang / Zheng Zeng

    Revista da Sociedade Brasileira de Medicina Tropical, Vol 52, Iss

    2019  

    Keywords Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2019-04-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical (SBMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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