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Article ; Online: Concern for nutrition and prodromal Parkinson's disease and actively respond to aging challenge

Zhihong WANG / Huijun WANG / Bing ZHANG / Gangqiang DING

环境与职业医学, Vol 40, Iss 2, Pp 119-

2023 Volume 121

Abstract: Parkinson's disease (PD) is a chronic neurodegenerative disease commonly seen in middle-aged and elderly people, and aging is the largest risk factor for PD. With acceleration of the aging process in China, the wellbeing and life quality of the elderly ... ...

Abstract	Parkinson's disease (PD) is a chronic neurodegenerative disease commonly seen in middle-aged and elderly people, and aging is the largest risk factor for PD. With acceleration of the aging process in China, the wellbeing and life quality of the elderly are expected to be disturbed by increasing prevalence of PD. The Community-based Cohort Study on Nervous System Diseases (CCSNSD) has established community population-based cohorts of epilepsy, Alzheimer's disease, and PD, respectively; baseline survey and one round of follow-up have finished so far. The CCSNSD collected data on demographics, community environment, diet, lifestyle, cognition, history of chronic diseases, and PD-related risk factors and facilitated exploration of the relationship between dietary nutrition and PD-related outcomes. This special column described status on prodromal Parkinson's disease (pPD) risk and its demographic & economic differences among people aged 55 and above in four provinces of China, and investigated the associations of red meat and processed meat products intake , dairy products intake, and cognitive function with pPD risk, respectively. Furthermore, one paper reviewed previous studies on dietary nutrition, lifestyle, and PD risks. However, the follow-up time of CCSNSD was relatively short as of the publishing of this column, longer follow-ups are required to allow studying potential factors and risk of incident PD combined with clinical examination and diagnosis of PD.
Keywords	nutrition ; cognition ; parkinson's disease ; prodromal parkinson's disease ; aging ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	610
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Editorial Committee of Journal of Environmental and Occupational Medicine
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Recent progress on associations of dietary nutrition and lifestyle with Parkinson's disease

Siting ZHANG / Xiaofang JIA / Jiguo ZHANG / Zhihong WANG

环境与职业医学, Vol 40, Iss 2, Pp 149-

2023 Volume 155

Abstract: With the expansion of aging population in China, the increasingly serious situation of Parkinson's disease (PD) threatens the physical and mental health and quality of life of middle-aged and elderly people, posing a great challenge to increase healthy ... ...

Abstract	With the expansion of aging population in China, the increasingly serious situation of Parkinson's disease (PD) threatens the physical and mental health and quality of life of middle-aged and elderly people, posing a great challenge to increase healthy life expectancy and realize the Healthy China Strategy. Previous studies showed some connections between dietary and lifestyle factors and PD and suggested that excessive intake of red meat might increase the risk of PD; however, coffee and tea, dietary antioxidants, n-3 polyunsaturated fatty acids, vitamin D, and vitamin B were associated with reducing the risk of PD or delaying the progression of PD, and dietary patterns with high intakes of fresh vegetables and fruits, legumes, whole grains, fish, and poultry meat were also associated with a reduced risk of PD. In addition, physical activity was a protective factor for PD, and smoking was also associated with a reduced risk of PD, but the related mechanisms were still unclear. This paper evaluated the relationships of factors like foods, nutrients, dietary patterns, and lifestyle with PD based on published literature, summarized the limitations of relevant studies, and provided useful enlightenment for PD prevention and control.
Keywords	parkinson's disease ; prodromal parkinson's disease ; nutrition ; lifestyle ; dietary pattern ; Medicine (General) ; R5-920 ; Toxicology. Poisons ; RA1190-1270
Subject code	910
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Editorial Committee of Journal of Environmental and Occupational Medicine
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Several interventions to alleviate pain in male patients undergoing office-based flexible cystoscopy

Zhihong Wang / Wuran Wei

Journal of Men's Health, Vol 18, Iss 1, p

a systematic review and meta-analysis

2021 Volume 010

Abstract: Background: The purpose of this study was to explore the ability of nonpharmacologic adjuvant interventions to alleviate pain in male patients during flexible cystoscopy (FC) under local anesthesia. Methods: Electronic databases including PubMed, the ... ...

Abstract	Background: The purpose of this study was to explore the ability of nonpharmacologic adjuvant interventions to alleviate pain in male patients during flexible cystoscopy (FC) under local anesthesia. Methods: Electronic databases including PubMed, the Cochrane Library, and Embase were searched to identify eligible clinical trials from inception to 31 December 2020, with no language restrictions. Two independent reviewers used Cochrane Collaboration tools to assess the selection criteria, methodological rigor and risk of bias. Statistical analyses were performed using STATA 14.2. Results: In total, 717 studies were initially identified, and fourteen randomized controlled trials were ultimately included. We observed that patients who underwent FC with higher irrigation pressures had significantly lower pain scores on the visual analog scale than their counterparts with lower irrigation pressure during FC (weight mean difference (WMD): −1.43; 95% confidence interval (CI): −1.72 to −1.14) with no between-study heterogeneity (p = 0.661). There were no significant differences in pain between immediate or delayed FC groups under the same local anesthetic (standard mean difference (SMD): −0.19; 95% CI: −0.39 to 0.01). A pooled analysis of three studies including 340 male patients showed that men who observed the cystoscopy on the monitor had significantly lower pain ratings compared to those who did not view the operation on the monitor (SMD: −0.64; 95% CI: −1.14 to −0.15). Two studies, including a total of 272 patients, assessed the influence of listening to music on pain and anxiety in male patients during FC. Our meta-analysis found that music significantly improved patient pain (WMD: −0.92; 95% CI: −1.29 to −0.54). Hand-holding and urination during FC also relieved pain and anxiety in male patients undergoing FC. Conclusions: We observed that elevated irrigation pressure, real-time cystoscopy visualization, and music therapy alleviated pain in male patients undergoing FC. Well-designed trials are needed to confirm ...
Keywords	flexible cystoscopy ; music ; pressure ; bag squeeze ; real-time visualization ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2021-07-01T00:00:00Z
Publisher	MRE Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Combination of InSAR with a Depression Angle Model for 3D Deformation Monitoring in Mining Areas

Zhihong Wang / Huayang Dai / Yueguan Yan / Jibo Liu / Jintong Ren

Remote Sensing, Vol 15, Iss 1834, p

2023 Volume 1834

Abstract: The current three-dimensional (3D) deformation monitoring methods, based on the single line-of-sight (LOS) interferometric synthetic aperture radar (InSAR) technology, are constructed by combining the deformation characteristics of mining subsidence ... ...

Abstract	The current three-dimensional (3D) deformation monitoring methods, based on the single line-of-sight (LOS) interferometric synthetic aperture radar (InSAR) technology, are constructed by combining the deformation characteristics of mining subsidence basins, which are incompletely suitable in the edge area of the subsidence basin and some large deformation gradient mines with surface uplift in the LOS direction.The 3D deformation monitoring method of InSAR combined with the surface displacement vector depression angle model (InSAR+ depression angle model) is proposed to obtain more detailed and accurate deformation information of the entire basin. This method first establishes a surface displacement vector depression angle model based on the probability integral method (PIM). The magnitude of the surface displacement vector—owing to the spatial relationship between the LOS direction and the surface displacement vector—is obtained because the horizontal movement direction field and the displacement vector depression angle field of the mining area determine the 3D directions of the surface displacement vector. Then, the PIM model is used to obtain the settlement information of the central area with a large deformation gradient. A complete subsidence basin of the mining area is received by combining the proposed method and the PIM. A total of 35 Sentinel-1A data from 31 March 2018 to 13 May 2019 and the leveling data were used to apply and analyze the accuracy of this method. The experimental results show that this method can obtain more accurate information on surface subsidence around the mining area. Moreover, the overall settlement is more consistent with the actual situation, and the monitoring ability is significantly improved compared with the InSAR and PIM.
Keywords	InSAR ; depression angle model ; PIM ; mining subsidence ; Science ; Q
Subject code	550
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: MiR-326 regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis.

Yiou, Wang / Zhihong, Wang / Shibai, Zhu / Shanni, Li / Wenwei, Qian

Human cell

2023 Volume 36, Issue 3, Page(s) 987–996

Abstract: The dysregulation of microRNAs plays a critical role in the development of rheumatoid arthritis (RA). This study aims to explore the functional significance of miR-326 in RA. The RT-qPCR results showed that miR-326 was downregulated in synovial tissues ... ...

Abstract	The dysregulation of microRNAs plays a critical role in the development of rheumatoid arthritis (RA). This study aims to explore the functional significance of miR-326 in RA. The RT-qPCR results showed that miR-326 was downregulated in synovial tissues of RA patients and RA fibroblast-like synoviocytes (RA-FLS). We found that miR-326 could target and reduce the expression of inhibitor of DNA binding 1 (Id1). MTT assay and flow cytometry were conducted to explore the biological function of miR-326. Our data revealed that the upregulation of miR-326 suppressed cell proliferation and induced apoptosis in RA-FLS. In collagen-induced arthritis mice, intraarticular injection of lentivirus carrying miR-326 overexpression vectors could reduce the arthritis score and attenuate synovial inflammation and cartilage destruction. We also found that long non-coding RNA-Ewing sarcoma-associated transcript 1 (lncRNA-EWSAT1) was significantly increased in RA synovial tissues and RA-FLS. The RNA immunoprecipitation and RNA pull-down assay indicated that lncRNA-EWSAT1 directly bound and negatively regulated the expression of miR-326. Knockdown of lncRNA-EWSAT1 could upregulate miR-326 expression and attenuate its proliferation inhibition and apoptosis induction effect in RA-FLS. In conclusion, the lncRNA-EWSAT1/miR-326 axis might provide a novel therapeutic target in the treatment of RA.
MeSH term(s)	Animals ; Mice ; Synoviocytes/metabolism ; RNA, Long Noncoding/physiology ; Cells, Cultured ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/therapy ; Arthritis, Rheumatoid/metabolism ; Apoptosis/genetics ; Cell Proliferation/genetics ; Fibroblasts/metabolism
Chemical Substances	RNA, Long Noncoding ; MicroRNAs
Language	English
Publishing date	2023-02-07
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1149134-6
ISSN	1749-0774 ; 0914-7470
ISSN (online)	1749-0774
ISSN	0914-7470
DOI	10.1007/s13577-023-00873-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Geochemical characteristics and hydrocarbon generation potential of main source rocks in the Upper Triassic Xujiahe Formation, Sichuan Basin, China

Zhihong Wang / Cuiguo Hao / Hui Jin / Junfeng Cun / Xueqiong Wu / Dongmei Bo / Yiqing Su

Frontiers in Earth Science, Vol

2023 Volume 11

Abstract: In order to have a comprehensive understanding of the characterization and hydrocarbon generation potential of the source rock in the Upper Triassic Xujiahe Formation, Sichuan Basin, the geochemical data of more than 1,500 cuttings and 106 core samples ... ...

Abstract	In order to have a comprehensive understanding of the characterization and hydrocarbon generation potential of the source rock in the Upper Triassic Xujiahe Formation, Sichuan Basin, the geochemical data of more than 1,500 cuttings and 106 core samples were collected and analyzed. The T3x5 member of Xujiahe formation show the highest average TOC content (3.63%) followed by the T3x1+2 and T3x3 members. The TOC contents of different members show a general decreasing trend from the bottom to the top in Xujiahe formation. From the rock pyrolysis and kerogen δ13C values, the source rock trend to be kerogen type III with minor amounts of type Ⅱ2. According to the Ro values, the Xujiahe source rock shows high maturity in the northwest and low maturity in the southeast. Most of the source rock in T3x1+2 members are in high to overmature stage, while most of the source rock in the T3x3 and T3x5 member are in the mature to high mature stage. By comparing the burial history and hydrocarbon generation evolution history of source rocks in central and western Sichuan basin, it can be found that the sedimentation rate differences during the Cretaceous period is the main cause of the thermal evolution difference of the source rock. The gas generation intensity and quantity of different members are also compared. The T3x5 member show the highest gas generation potential followed by the T3x31 and the T3x1+2 members. In general, horizontally, the source rock of Xujiahe formation in Sichuan Basin is characterized by great thickness, high maturity, and high gas generation intensity in the northwest, which are gradually decrease to the southeast. Vertically, the T3x5 member show the highest gas generation content, which account for 39.6% of the total amount.
Keywords	Sichuan Basin ; Xujiahe Formation ; source rock ; geochemical characteristic ; gas generation potential ; Science ; Q
Subject code	550
Language	English
Publishing date	2023-07-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Support for Economic Inequality and Tax Evasion

William E. Shafer / Zhihong Wang / Tien-Shih Hsieh

Sustainability, Vol 12, Iss 8025, p

2020 Volume 8025

Abstract: The primary focus of this paper is on the relationship between taxpayers’ ideological support for economic inequality and the likelihood they will commit tax evasion. We also propose that Machiavellianism will mediate the relationship between support for ...

Abstract	The primary focus of this paper is on the relationship between taxpayers’ ideological support for economic inequality and the likelihood they will commit tax evasion. We also propose that Machiavellianism will mediate the relationship between support for inequality and tax evasion. The results, based on a survey of experienced taxpayers, partially support our expectations. Ideological support for economic inequality had a significant positive association with Machiavellianism, which in turn had a strong positive association with tax evasion intentions. Machiavellianism fully mediated the relationship between support for inequality and tax evasion. This is the first study to investigate the potential influence of support for economic inequality on taxpayers’ evasion decisions. In light of the findings, we suggest that support for the persistence of economic inequality and related ideological beliefs may pose fundamental threats to governments’ ability to sustain just and fair socioeconomic systems. We also argue that such ideologies are likely to be associated with the ethical decisions of corporate managers, business owners and professionals across a variety of decision contexts, but their influence has largely been ignored in the business and society and sustainability literature.
Keywords	economic inequality ; social dominance ; Machiavellianism ; tax evasion ; socioeconomic sustainability ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	338
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Design on electrohydraulic servo driving system with walking assisting control for lower limb exoskeleton robot

Buyun Wang / Yi Liang / Dezhang Xu / Zhihong Wang / Jing Ji

International Journal of Advanced Robotic Systems, Vol

2021 Volume 18

Abstract: According to the characteristics of human gait and the requirements of power assistance, locomotive mechanisms and electrohydraulic servo driving are designed on a lower limb exoskeleton robot, in which the miniaturization and lightweight of driving ... ...

Abstract	According to the characteristics of human gait and the requirements of power assistance, locomotive mechanisms and electrohydraulic servo driving are designed on a lower limb exoskeleton robot, in which the miniaturization and lightweight of driving system are realized. The kinematics of the robot is analyzed and verified via the typical movements of the exoskeleton. In this article, the simulation on the power of joints during level walking was analyzed in ADAMS 2016, which is a multibody simulation and motion analysis software. Motion ranges and driving strokes are then optimized. A proportional integral derivative (PID) control method with error estimation and pressure compensation is proposed to satisfy the requirements of joints power assistance and comply with the motion of human lower limb. The proposed method is implemented into the exoskeleton for assisted walking and is verified by experimental results. Finally, experiments show that the tracking accuracy and power-assisted performance of exoskeleton robot joints are improved.
Keywords	Electronics ; TK7800-8360 ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	629
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
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Article ; Online: Satellite Remote Sensing of Water Quality Variation in a Semi-Enclosed Bay (Yueqing Bay) under Strong Anthropogenic Impact

Bozhong Zhu / Yan Bai / Zhao Zhang / Xianqiang He / Zhihong Wang / Shugang Zhang / Qian Dai

Remote Sensing, Vol 14, Iss 550, p

2022 Volume 550

Abstract: The semi-enclosed bays impacted by heavy anthropogenic activities have weak water exchange and purification capacities. Most of the sea bays have suffered severe eutrophication, water quality deterioration, ecosystem degradation and other problems. ... ...

Abstract	The semi-enclosed bays impacted by heavy anthropogenic activities have weak water exchange and purification capacities. Most of the sea bays have suffered severe eutrophication, water quality deterioration, ecosystem degradation and other problems. Although many countries and local governments have carried out corresponding environmental protection actions, the evaluation of their effectiveness still requires monitoring technology and data support for long-term water environment change. In this study, we take Yueqing Bay, the fourth largest bay in China, as a case to study the satellite-based water quality monitoring and variation analysis. We established a nutrient retrieval model for Yueqing Bay to produce a long-term series of nutrient concentration products in Yueqing Bay from 2013 to 2020, based on Landsat remote sensing images and long-term observation data, combined with support vector machine learning and water temperature and satellite spectra as input parameters, and then we analyzed its spatiotemporal variations and driving factors. In general, nutrient concentrations in the western part of the bay were higher than those in the eastern part. Levels of dissolved inorganic nitrogen (DIN) were lower in summer than in spring and winter, and reactive phosphate (PO 4 -P) levels were lower in summer and higher in autumn. In terms of natural factors, physical effects (e.g., seasonal variations in flow field) and biological effects (e.g., seasonal differences in the intensity of plankton photosynthesis) were the main causes of seasonal differences in nutrient concentration in Yueqing Bay. Nutrient concentration generally increased from 2013 to 2015 but decreased slightly after 2015. Over the past decade, the economy and industry of Yueqing Bay basin have developed rapidly. Wastewater resulting from anthropogenic production and consumption was transported via streams into Yueqing Bay, leading to the continuous increase in nutrient concentrations (the variation rates: <math ...<br />
Keywords	nutrient ; satellite remote sensing ; support vector machine ; long time series ; driving factor ; Yueqing Bay ; Science ; Q
Subject code	910
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Analysis of the disease burden trend of malignant tumors of the female reproductive system in China from 2006 to 2020

Xiting Han / Zhihong Wang / Dongmei Huang / Kehong Deng / Qian Wang / Cancan Li / Jicun Zhu

BMC Women's Health, Vol 22, Iss 1, Pp 1-

2022 Volume 9

Abstract: Plain English summary Malignant tumors of the female reproductive system are the leading causes of women's mortality worldwide, mainly including cervical cancer, uterine cancer and ovarian cancer. Numerous studies have reported mortality changes in the ... ...

Abstract	Plain English summary Malignant tumors of the female reproductive system are the leading causes of women's mortality worldwide, mainly including cervical cancer, uterine cancer and ovarian cancer. Numerous studies have reported mortality changes in the three primary reproductive system cancers among different countries, with inconsistent temporal trends. In 2020, almost 17.51% of malignant tumors of the female reproductive system deaths occurred in China because of the large population base and severe aging. However, there are limited studies on the disease burden of malignant tumors of the female reproductive system in China. This study analyzed the mortality, YLL and LLE of cervical cancer, uterine cancer and ovarian cancer using the National Death Cause Surveillance Dataset from 2006 to 2020. The findings revealed that mortality and disease burden of malignant tumors of the reproductive system showed no significant change. The mortality and disease burden of uterine cancer decreased significantly, but that of cervical cancer and ovarian cancer remain high. Cervical cancer has a higher mortality and disease burden than uterine cancer and ovarian cancer, making it the most severe malignant tumor of the female reproductive system. Screening and HPV vaccination will reduce the mortality and disease burden of cervical cancer in China, but this effect will take many years to manifest. Screening and prevention strategies for high-risk groups of uterine cancer and ovarian cancer should be established as soon as possible. In summary, the management and monitoring of malignant tumors of the female reproductive system should be strengthened.
Keywords	Female reproductive system ; Malignant tumor ; Mortality ; Disease burden ; Gynecology and obstetrics ; RG1-991 ; Public aspects of medicine ; RA1-1270
Subject code	610
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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