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  1. AU="Zhiping, Wei"
  2. AU="Ezaz, Md Shafiul"
  3. AU="He, Yi Jie"
  4. AU="Sarkar, Bidhan Chandra"
  5. AU="Glenn, Christensen"
  6. AU="Korobov, A. A."
  7. AU="Farzaneh Ashrafi"
  8. AU="Mitamura, Yasuhito"
  9. AU="Mayfield, Margaret M"
  10. AU="Rebsomen, L"
  11. AU="Abtie Abebaw"
  12. AU="Treitz, Christian"
  13. AU=Abd-Elsayed Alaa
  14. AU="Vesajoki, Marja" AU="Vesajoki, Marja"
  15. AU=Lewiecki E Michael
  16. AU=von Bubnoff Nikolas
  17. AU="Tang, Walfred W C"
  18. AU=Hashitani Hikaru
  19. AU="Löw, Martina"
  20. AU="Robertson, Leon S"
  21. AU="Wright, Aaron T"
  22. AU="Jones, T. B."
  23. AU=Shirtliff Mark E.
  24. AU="Riis, Kamilla R"
  25. AU="Xu, Leyao"
  26. AU="Udayakumar, Karthikrajan Parasuraman"
  27. AU="Fry, Brian"

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  1. Artikel ; Online: Regulatory Effect of Mesenchymal Stem Cells on T Cell Phenotypes in Autoimmune Diseases

    Zhiping Wei / Jintao Yuan / Gaoying Wang / Dickson Kofi Wiredu Ocansey / Zhiwei Xu / Fei Mao

    Stem Cells International, Vol

    2021  Band 2021

    Abstract: Research on mesenchymal stem cells (MSCs) starts from the earliest assumption that cells derived from the bone marrow have the ability to repair tissues. Several scientists have since documented the crucial role of bone marrow-derived MSCs (BM-MSCs) in ... ...

    Abstract Research on mesenchymal stem cells (MSCs) starts from the earliest assumption that cells derived from the bone marrow have the ability to repair tissues. Several scientists have since documented the crucial role of bone marrow-derived MSCs (BM-MSCs) in processes such as embryonic bone and cartilage formation, adult fracture and tissue repair, and immunomodulatory activities in therapeutic applications. In addition to BM-MSCs, several sources of MSCs have been reported to possess tissue repair and immunoregulatory abilities, making them potential treatment options for many diseases. Therefore, the therapeutic potential of MSCs in various diseases including autoimmune conditions has been explored. In addition to an imbalance of T cell subsets in most patients with autoimmune diseases, they also exhibit complex disease manifestations, overlapping symptoms among diseases, and difficult treatment. MSCs can regulate T cell subsets to restore their immune homeostasis toward disease resolution in autoimmune conditions. This review summarizes the role of MSCs in relieving autoimmune diseases via the regulation of T cell phenotypes.
    Schlagwörter Internal medicine ; RC31-1245
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Hindawi Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: The Effects of Mesenchymal Stem Cell on Colorectal Cancer

    Jintao Yuan / Zhiping Wei / Xinwei Xu / Dickson Kofi Wiredu Ocansey / Xiu Cai / Fei Mao

    Stem Cells International, Vol

    2021  Band 2021

    Abstract: Colorectal cancer (CRC) is a common malignant tumor of the gastrointestinal tract with nonobvious early symptoms and late symptoms of anemia, weight loss, and other systemic symptoms. Its morbidity and fatality rate are next only to gastric cancer, ... ...

    Abstract Colorectal cancer (CRC) is a common malignant tumor of the gastrointestinal tract with nonobvious early symptoms and late symptoms of anemia, weight loss, and other systemic symptoms. Its morbidity and fatality rate are next only to gastric cancer, esophageal cancer, and primary liver cancer among digestive malignancies. In addition to the conventional surgical intervention, other therapies such as radiotherapy and chemotherapy and new treatment methods such as biologics and microbiological products have been introduced. As a promising cell therapy, mesenchymal stem cell (MSC) has attracted extensive research attention. MSCs are early undifferentiated pluripotent stem cells, which have the common features of stem cells, including self-replication, self-division, self-renewal, and multidirectional differentiation. MSCs come from a wide range of sources and can be extracted from a variety of tissues such as the bone marrow, umbilical cord, and fat. Current studies have shown that MSCs have a variety of biological functions such as immune regulation, tissue damage repair, and therapeutic effects on tumors such as CRC. This review outlines the overview of MSCs and CRC and summarizes the role of MSC application in CRC.
    Schlagwörter Internal medicine ; RC31-1245
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Hindawi Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: miR-215 Inhibits Colorectal Cancer Cell Migration and Invasion via Targeting Stearoyl-CoA Desaturase

    Xinhua Xu / Yan Ding / Jun Yao / Zhiping Wei / Haipeng Jin / Chen Chen / Jun Feng / Rongbiao Ying

    Computational and Mathematical Methods in Medicine, Vol

    2020  Band 2020

    Abstract: Background. This study was aimed at exploring the effects of miR-215 and its target gene stearoyl-CoA desaturase (SCD) on colorectal cancer (CRC) cell migration and invasion. Methods. Here, we analyzed the relationship between miR-215 and SCD, as well as ...

    Abstract Background. This study was aimed at exploring the effects of miR-215 and its target gene stearoyl-CoA desaturase (SCD) on colorectal cancer (CRC) cell migration and invasion. Methods. Here, we analyzed the relationship between miR-215 and SCD, as well as the regulation of miR-215 on CRC cells. We constructed wild-type and mutant plasmids of SCD to identify whether SCD was a target gene of miR-215 by using a luciferase reporter assay. The expression of miR-215 and SCD was detected by quantitative real-time polymerase chain reaction (qRT-PCR) and western blot, respectively. MTT, wound healing, and Transwell assays were applied to determine the effect of miR-215 on CRC cell proliferation, migration, and invasion. Results. It was found that miR-215 expression was significantly decreased in CRC tissue while SCD was highly expressed compared with those in adjacent normal tissue. The luciferase reporter assay indicated that SCD was a direct target gene of miR-215. Functional analysis revealed that miR-215 overexpression significantly inhibited CRC cell proliferation, migration, and invasion in vitro. In addition, the result of rescue experiments showed that overexpression of SCD could promote the proliferation, migration, and invasion of CRC cells, and the carcinogenic effect of SCD could be inhibited by miR-215. Conclusions. Taken together, our findings suggested that miR-215 could inhibit CRC cell migration and invasion via targeting SCD. The result could eventually contribute to the treatment for CRC.
    Schlagwörter Computer applications to medicine. Medical informatics ; R858-859.7
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag Hindawi Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Diagnostic applicability of confocal laser scanning microscopy in tinea corporis.

    Liansheng, Zhong / Xin, Jin / Cheng, Quan / Zhiping, Wei / Yanqun, Liu

    International journal of dermatology

    2013  Band 52, Heft 10, Seite(n) 1281–1282

    Mesh-Begriff(e) Dermoscopy/methods ; Humans ; Hydroxides ; Hyphae ; Indicators and Reagents ; Microscopy, Confocal/methods ; Potassium Compounds ; Tinea/diagnosis
    Chemische Substanzen Hydroxides ; Indicators and Reagents ; Potassium Compounds ; potassium hydroxide (WZH3C48M4T)
    Sprache Englisch
    Erscheinungsdatum 2013-10
    Erscheinungsland England
    Dokumenttyp Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/j.1365-4632.2011.05144.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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