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  1. Article ; Online: Cemento-ossifying fibroma resection combined with heterotopic canine autotransplantation: a case report.

    Han, Yue / Liu, Yixuan / Zhao, Jihong / Zhong, Haoyan

    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

    2024  Volume 41, Issue 6, Page(s) 731–736

    Abstract: Cemento-ossifying fibroma (COF) is a mesenchymal benign odontogenic tumor, which may lead to impacted or ectopic permanent teeth. Autotransplantation of teeth is a surgical process, in which a tooth is transplanted from one position to another in the ... ...

    Abstract Cemento-ossifying fibroma (COF) is a mesenchymal benign odontogenic tumor, which may lead to impacted or ectopic permanent teeth. Autotransplantation of teeth is a surgical process, in which a tooth is transplanted from one position to another in the same individual. This method can effectively restore the patient's mastication and aesthetics and is feasible in replacing missing teeth. This study reports a case of simultaneous COF resection combined with heterotopic canine autotransplantation to repair dentition defect, which effectively promotes the restoration of bone continuity and stability and achieves immediate and long-term aesthetic function requirements.
    MeSH term(s) Humans ; Cementoma/pathology ; Cementoma/surgery ; Transplantation, Autologous ; Esthetics, Dental ; Fibroma, Ossifying/surgery ; Fibroma, Ossifying/pathology ; Odontogenic Tumors/pathology ; Odontogenic Tumors/surgery
    Language Chinese
    Publishing date 2024-04-10
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 1202342-5
    ISSN 2618-0456 ; 1000-1182
    ISSN (online) 2618-0456
    ISSN 1000-1182
    DOI 10.7518/hxkq.2023.2023103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mepivacaine dosing for spinal anesthesia in pediatric orthopedic surgery: a retrospective chart review.

    Carley, Michelle / Sheetz, Miriam / Lauzadis, Justas / Zhong, Haoyan / DelPizzo, Kathryn

    Regional anesthesia and pain medicine

    2024  

    Abstract: Background: Mepivacaine is an intermediate-acting local anesthetic used for spinal anesthesia in adults. Currently, there are no published dosing guidelines for spinal mepivacaine in patients under age 18.: Aims: The purpose of this study is to ... ...

    Abstract Background: Mepivacaine is an intermediate-acting local anesthetic used for spinal anesthesia in adults. Currently, there are no published dosing guidelines for spinal mepivacaine in patients under age 18.
    Aims: The purpose of this study is to describe the clinically used doses of mepivacaine by weight and age for orthopedic surgery in pediatrics.
    Methods: We performed a retrospective chart review of patients aged 0-18 who received mepivacaine for spinal anesthesia from 2016 to 2022. We performed a secondary analysis for patients aged 0-18 who received spinal anesthesia with bupivacaine or chloroprocaine.
    Results: The data extraction yielded 3627 single-shot mepivacaine spinals. Patient age ranged from 5 to 18 years. Median dosage in milligrams/kilograms (mg/kg) of mepivacaine was calculated for each age group. Our analysis revealed that dosage in mg/kg decreased by patient age and began to plateau at age 15. Bupivacaine was the most common single-shot spinal agent in patients under age 10. After age 10, mepivacaine was more common. Chloroprocaine began to be used in patients older than 8 years.
    Conclusions: We describe mepivacaine dosage as a function of age and weight in patients younger than 18 years. As age and weight increased, a lower dose of mepivacaine per kg was administered for spinal anesthesia.
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2023-105093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effectiveness evaluation of autotransplanted teeth after performing extraoral endodontic surgery instead of conventional root canal therapy.

    Liao, Fenglin / Wang, Hui / Zhao, Jihong / Zhang, Biao / Zhong, Haoyan

    BMC oral health

    2023  Volume 23, Issue 1, Page(s) 1005

    Abstract: Purpose: The aim of this study was to examine the viability and efficacy of utilizing extraoral apicoectomy and retrograde filling in combination to seal the root canal system of mature molars without the need for root canal therapy (RCT) during the ... ...

    Abstract Purpose: The aim of this study was to examine the viability and efficacy of utilizing extraoral apicoectomy and retrograde filling in combination to seal the root canal system of mature molars without the need for root canal therapy (RCT) during the autotransplantation of teeth (ATT).
    Materials and methods: This study screened 27 patients who received ATT at the Department of Oral Surgery in the Hospital of Stomatology from 2019 to 2021. Extraoral apicoectomy and retrograde filling were performed, while RCT was temporarily not performed. The study analysed the periodontal status and masticatory function of transplanted teeth one to three years postoperation and used cone-beam computed tomography (CBCT) and periapical radiograph (PA) to evaluate the integrity of the periodontal space and intra/periapical inflammation. The potential predictors of survival/success were analysed statistically. We also conducted questionnaires and chewing efficiency tests.
    Results: In this study, 27 TTs from 27 patients were found to be fully functional in terms of chewing ability. The overall survival rate was 100% (27/27), and the success rate was 70.4% (19/27). A total of 90.9% (20/22) of patients reported being satisfied or very satisfied with their TTs. Additionally, the chewing efficiency of the transplantation side was on average 82.0% of that of the healthy side, with a significant difference between the two sides (P < 0.05). None of the potential predictors were found to significantly affect the success or survival of the transplanted tooth (TT).
    Conclusion: The combination of extraoral apicoectomy and retrograde filling in TT showed promising outcomes, but further clinical cases and longer follow-up times are still required to validate the treatment plan.
    MeSH term(s) Humans ; Transplantation, Autologous ; Root Canal Therapy/methods ; Apicoectomy ; Molar ; Treatment Outcome ; Root Canal Filling Materials/therapeutic use
    Chemical Substances Root Canal Filling Materials
    Language English
    Publishing date 2023-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-03733-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Application effect of computer-aided design combined with three-dimensional printing technology in autologous tooth transplantation: a retrospective cohort study.

    Han, Shuang / Wang, Hui / Chen, Jue / Zhao, Jihong / Zhong, Haoyan

    BMC oral health

    2022  Volume 22, Issue 1, Page(s) 5

    Abstract: Background: The activity of donor periodontal membrane is the key factor of autologous tooth healing. The application of digital aided design, 3D printing model and guide plate in autotransplantation of tooth (ATT) is expected to reduce the damage of ... ...

    Abstract Background: The activity of donor periodontal membrane is the key factor of autologous tooth healing. The application of digital aided design, 3D printing model and guide plate in autotransplantation of tooth (ATT) is expected to reduce the damage of periodontal membrane and preserve the activity of periodontal membrane, so as to improve the success rate of ATT. This study tried to prove the role of digital technology in improving the success rate of ATT, although there are differences in model accuracy in practice.
    Methods: We included 41 tooth autotransplantation cases which assisted by 3D-printed donor models and surgical guides and divided them into two groups in accordance with whether the donor tooth could be placed successfully after the preparation of alveolar socket guided by the model tooth. Then, we compared and analyzed the preparation time of alveolar socket, extra-alveolar time, and number of positioning trials of the donor tooth between the two groups. We also included a comparison of the in vitro time of the donor tooth with that of 15 min. The incidence of complications was included in the prognostic evaluation.
    Results: The mean preparation time of the alveolar socket, mean extra-alveolar time of donor tooth, and mean number of positioning trials with donor tooth of 41 cases were 12.73 ± 6.18 min, 5.56 ± 3.11 min, and 2.61 ± 1.00, respectively. The group wherein the donor tooth cannot be placed successfully (15.57 ± 6.14 min, 7.29 ± 2.57 min) spent more preparation time of alveolar socket and extra-alveolar time than the group wherein the donor tooth can be placed successfully (9.75 ± 4.73 min, 3.75 ± 2.57 min). The number of positioning trials with the donor tooth of the group wherein the donor tooth cannot be placed successfully (3.19 ± 0.75) was higher than that of the other group (2.00 ± 0.86). There was no significant difference in survival rates between the two groups.
    Conclusions: Compared with the traditional tooth autotransplantation, the introduction of computer-aided design combined with 3D printing of the model tooth and surgical guides evidently shortens the preparation time of the alveolar socket and the extra-alveolar time of the donor tooth and reduces the number of positioning trials with the donor tooth regardless of the shape deviation between the model and actual teeth.
    MeSH term(s) Computer-Aided Design ; Cone-Beam Computed Tomography/methods ; Humans ; Printing, Three-Dimensional ; Retrospective Studies ; Surgery, Computer-Assisted/methods ; Tooth ; Transplantation, Autologous/methods
    Language English
    Publishing date 2022-01-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-021-02030-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Trends of liposomal bupivacaine utilization in major lower extremity total joint arthroplasty in the USA: a population-based study.

    Stundner, Ottokar / Hoerner, Elisabeth / Zhong, Haoyan / Poeran, Jashvant / Liu, Jiabin / Illescas, Alex / Memtsoudis, Stavros G

    Regional anesthesia and pain medicine

    2024  Volume 49, Issue 2, Page(s) 139–143

    Abstract: Introduction: Liposomal bupivacaine has been marketed for the achievement of long-acting local or regional anesthesia after major lower extremity total joint arthroplasty. However, it is comparatively expensive and controversy remains regarding its ... ...

    Abstract Introduction: Liposomal bupivacaine has been marketed for the achievement of long-acting local or regional anesthesia after major lower extremity total joint arthroplasty. However, it is comparatively expensive and controversy remains regarding its ability to decrease healthcare costs. With mounting evidence suggesting non-superiority in efficacy, compared with plain bupivacaine, we sought to investigate trends in liposomal bupivacaine use and identify changes in practice.
    Methods: We identified adult patients from the Premier Healthcare Database who underwent elective total joint arthroplasty between 2012 and 2021. Prevalence and trends of liposomal bupivacaine utilization were compared on the individual patient and hospital levels. Log-rank tests were performed to assess the influence of location, teaching status, or hospital size on time to hospital-level liposomal bupivacaine termination.
    Results: Among 103,165 total joint arthroplasty cases, liposomal bupivacaine use increased between 2012 and 2015 (from 0.4% to 22.8%) and decreased by approximately 1%-3% annually thereafter (15.7% in 2021). Liposomal bupivacaine was ever used in approximately 60% of hospitals. Hospital-level initiation of liposomal bupivacaine use peaked in 2014 and decreased thereafter (from 32.8% in 2013 to 4.3% in 2021), while termination rates increased (from 1.4% in 2014 to 9.9% in 2019). Non-teaching hospitals and those located in the South and West regions were more likely to retain liposomal bupivacaine longer than teaching or Midwest/Northeast hospitals, respectively (p=0.023 and p=0.014).
    Discussion: Liposomal bupivacaine use peaked around 2015 and has been declining thereafter on individual patient and hospital levels. How these trends correlate with health outcomes and expenditures would be a strategic target for future research.
    MeSH term(s) Adult ; Humans ; Anesthetics, Local ; Pain, Postoperative ; Arthroplasty, Replacement, Knee ; Liposomes ; Pain Measurement ; Bupivacaine
    Chemical Substances Anesthetics, Local ; Liposomes ; Bupivacaine (Y8335394RO)
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2023-104784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Does the impact of peripheral nerve blocks vary by age and comorbidity subgroups? A nationwide population-based study.

    Zhong, Haoyan / Poeran, Jashvant / Cozowicz, Crispiana / Athanassoglou, Vassilis / Illescas, Alex / Memtsoudis, Stavros G / Liu, Jiabin

    Regional anesthesia and pain medicine

    2024  Volume 49, Issue 4, Page(s) 260–264

    Abstract: Introduction: A large body of literature suggests that peripheral nerve blockade (PNB) is associated with improved perioperative outcomes in total hip and knee joint arthroplasty patients. However, it is unclear to what extent this association exists ... ...

    Abstract Introduction: A large body of literature suggests that peripheral nerve blockade (PNB) is associated with improved perioperative outcomes in total hip and knee joint arthroplasty patients. However, it is unclear to what extent this association exists across patient subgroups based on age and health status.
    Methods: Patients who underwent total joint arthroplasty were identified from the Premier Healthcare database (2006-2019). Mixed-effects models were applied to assess the relationship between exposure of interest (PNB use on the day of surgery) and various outcomes (postoperative respiratory complications, acute renal failure, delirium, intensive care unit admission, prolonged length of stay, and high opioid consumption) across multiple subgroups stratified by patient age and pre-existing comorbidities.
    Results: PNB use and outcome association varies based on the patient's health and age characteristics. For adults and older adults with excellent or fair, there was a decrease in the likelihood of respiratory complication with the use of PNB (OR: 0.92, 95% CI 0.86 to 0.98; OR: 0.88, 95% CI 0.81 to 0.95; OR: 0.94, 95% CI 0.89 to 0.99, respectively). Peripheral nerve blocks were also associated with a reduction in the odds of high opioid consumption across all categories except adult patients in poor health.
    Conclusion: PNB use is associated with beneficial effects more commonly observed among patients with a lower comorbidity burden, without a clear pattern of association with patient age.
    MeSH term(s) Humans ; Aged ; Nerve Block/adverse effects ; Analgesics, Opioid/adverse effects ; Peripheral Nerves ; Postoperative Complications/epidemiology ; Comorbidity ; Pain, Postoperative/etiology ; Retrospective Studies
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2022-104150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Impact of sugammadex and neostigmine on outcome after major orthopaedic surgery: A population-based analysis.

    Cozowicz, Crispiana / Zhong, Haoyan / Poeran, Jashvant / Illescas, Alex / Liu, Jiabin / Poultsides, Lazaros A / Athanassoglou, Vassilis / Memtsoudis, Stavros G

    European journal of anaesthesiology

    2024  Volume 41, Issue 5, Page(s) 374–380

    Abstract: Background: Residual neuromuscular blockade after surgery remains a major concern given its association with pulmonary complications. However, current clinical practices with and the comparative impact on perioperative risk of various reversal agents ... ...

    Abstract Background: Residual neuromuscular blockade after surgery remains a major concern given its association with pulmonary complications. However, current clinical practices with and the comparative impact on perioperative risk of various reversal agents remain understudied.
    Objective: We investigated the use of sugammadex and neostigmine in the USA, and their impact on postoperative complications by examining national data.
    Design: This population-based retrospective study used national Premier Healthcare claims data.
    Setting and participants: Patients undergoing total hip/knee arthroplasty (THA, TKA), or lumbar spine fusion surgery between 2016 and 2019 in the United States who received neuromuscular blocking agents.
    Intervention: The effects of sugammadex and neostigmine for pharmacologically enhanced reversal were compared with each other and with controls who received no reversal agent.
    Main outcomes: included pulmonary complications, cardiac complications, and a need for postoperative ventilation. Mixed-effects regression models compared the outcomes between neostigmine, sugammadex, and controls. We report odds ratios (OR) and 95% confidence intervals (CI). Bonferroni-adjusted P values of 0.008 were used to indicate significance.
    Results: Among 361 553 patients, 74.5% received either sugammadex (20.7%) or neostigmine (53.8%). Sugammadex use increased from 4.4% in 2016 to 35.4% in 2019, whereas neostigmine use decreased from 64.5% in 2016 to 43.4% in 2019. Sugammadex versus neostigmine or controls was associated with significantly reduced odds for cardiac complications (OR 0.86, 95% CI, 0.80 to 0.92 and OR 0.83, 95% CI, 0.78 to 0.89, respectively). Both sugammadex and neostigmine versus controls were associated with reduced odds for pulmonary complications (OR 0.85, 95% CI, 0.77 to 0.94 and OR 0.91, CI 0.85 to 0.98, respectively). A similar pattern of sugammadex and neostigmine was observed for a reduction in severe pulmonary complications, including the requirement of invasive ventilation (OR 0.54, 95% CI, 0.45 to 0.64 and OR 0.53, 95% CI, 0.46 to 0.6, respectively).
    Conclusions: Population-based data indicate that sugammadex and neostigmine both appear highly effective in reducing the odds of severe life-threatening pulmonary complications. Sugammadex, especially, was associated with reduced odds of cardiac complications.
    MeSH term(s) Humans ; Neostigmine/adverse effects ; Sugammadex ; Retrospective Studies ; Neuromuscular Blockade/adverse effects ; Orthopedic Procedures ; Cholinesterase Inhibitors/adverse effects
    Chemical Substances Neostigmine (3982TWQ96G) ; Sugammadex (361LPM2T56) ; Cholinesterase Inhibitors
    Language English
    Publishing date 2024-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 605770-6
    ISSN 1365-2346 ; 0265-0215
    ISSN (online) 1365-2346
    ISSN 0265-0215
    DOI 10.1097/EJA.0000000000001979
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  8. Article ; Online: Women authorship in pain research: A bibliometric analysis from 2002 to 2021.

    Zhong, Haoyan / Poeran, Jashvant / Cozowicz, Crispiana / Illescas, Alex / Liu, Jiabin / Memtsoudis, Stavros G

    European journal of pain (London, England)

    2023  Volume 27, Issue 8, Page(s) 1036–1040

    Abstract: Objectives: There is a lack of data on the distribution of women first and senior authorships in pain journals. Using articles published in top North American pain journals over the past two decades, we sought to describe the prevalence and changes in ... ...

    Abstract Objectives: There is a lack of data on the distribution of women first and senior authorships in pain journals. Using articles published in top North American pain journals over the past two decades, we sought to describe the prevalence and changes in women representation among first and last authors.
    Methods: We retrieved all published research articles in four pain journals (Regional Anesthesia and Pain Medicine, Clinical Journal of Pain, Pain and The Journal of Pain) from 2002 to 2021 using the easyPubMed package. Subsequently, the 'gender' package in R was used to determine authors' gender by first names. Trends in gender authorship change over time were assessed.
    Results: The final cohort consisted of 20,981 authors (from an initial total of 11,842 publications and 23,684 authors retrieved). Women authors were more often first compared to senior authors (46.7% vs. 30.5%). The proportion of women first authors (46.2% in 2002 vs. 48.4% in 2021) and women senior authors (22.4% in 2002 vs. 36.3% in 2021) increased over the course of the study period (all p-value <0.001). The Clinical Journal of Pain having the highest percentage of women authors and Regional Anesthesia and Pain Medicine had the lowest percentage of women authors.
    Discussion: Our data demonstrated increasing women authorship in pain journals in the past 20 years, largely driven by an increase in first authorships. There still remains a large gap between first and senior authorship, indicative of disparity in the role that women play in research.
    MeSH term(s) Humans ; Female ; Authorship ; Bibliometrics ; Research ; Pain/epidemiology
    Language English
    Publishing date 2023-06-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1390424-3
    ISSN 1532-2149 ; 1090-3801
    ISSN (online) 1532-2149
    ISSN 1090-3801
    DOI 10.1002/ejp.2143
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  9. Article ; Online: Neuraxial Use Among Total Knee and Hip Arthroplasty Patients With Multiple Sclerosis or Myasthenia Gravis.

    Illescas, Alex / Zhong, Haoyan / Liu, Jiabin / Cozowicz, Crispiana / Poeran, Jashvant / Memtsoudis, Stavros G

    Anesthesia and analgesia

    2023  Volume 136, Issue 6, Page(s) 1182–1188

    Abstract: Background: Surgical patients with preexisting neurological diseases create greater challenges to perioperative management, and choice of anesthetic is often complicated. We investigated neuraxial anesthesia use in total knee and hip arthroplasty (TKA/ ... ...

    Abstract Background: Surgical patients with preexisting neurological diseases create greater challenges to perioperative management, and choice of anesthetic is often complicated. We investigated neuraxial anesthesia use in total knee and hip arthroplasty (TKA/THA) recipients with multiple sclerosis or myasthenia gravis compared to the general population.
    Methods: We retrospectively analyzed patients undergoing a TKA/THA with a diagnosis of multiple sclerosis or myasthenia gravis (Premier Health Database, 2006-2019). The primary outcome was neuraxial anesthesia use in multiple sclerosis or myasthenia gravis patients compared to the general population. Secondary outcomes were length of stay, intensive care unit admission, and mechanical ventilation. We measured the association between the aforementioned subgroups and neuraxial anesthesia use. Subsequently, subgroup-specific associations between neuraxial anesthesia and secondary outcomes were measured. We report odds ratios (ORs) and 95% confidence intervals (CIs).
    Results: Among 2,184,193 TKA/THAs, 7559 and 3176 had a multiple sclerosis or myasthenia gravis diagnosis, respectively. Compared to the general population, neuraxial anesthesia use was lower in multiple sclerosis patients (OR, 0.61; CI, 0.57-0.65; P < .0001) and no different in myasthenia gravis patients (OR, 1.05; CI, 0.96-1.14; P = .304). Multiple sclerosis patients administered neuraxial anesthesia (compared to those without neuraxial anesthesia) had lower odds of prolonged length of stay (OR, 0.63; CI, 0.53-0.76; P < .0001) mirroring neuraxial anesthesia benefits seen in the general population.
    Conclusions: Neuraxial anesthesia use was lower in surgical patients with multiple sclerosis compared to the general population but no different in those with myasthenia gravis. Neuraxial use was associated with lower odds of prolonged length of stay.
    MeSH term(s) Humans ; Arthroplasty, Replacement, Hip/adverse effects ; Arthroplasty, Replacement, Knee/adverse effects ; Retrospective Studies ; Multiple Sclerosis/complications ; Multiple Sclerosis/diagnosis ; Multiple Sclerosis/surgery ; Anesthesia, General/adverse effects ; Treatment Outcome ; Myasthenia Gravis/diagnosis ; Myasthenia Gravis/surgery ; Postoperative Complications/etiology ; Postoperative Complications/epidemiology
    Language English
    Publishing date 2023-03-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Anesthesia practice among joint arthroplasty patients with a previous lumbar spine surgery.

    Illescas, Alex / Zhong, Haoyan / Cozowicz, Crispiana / Poeran, Jashvant / Memtsoudis, Stavros G / Liu, Jiabin

    Journal of clinical anesthesia

    2023  Volume 90, Page(s) 111222

    Abstract: Study objective: To analyze the use of neuraxial techniques in total hip or knee arthroplasty patients who previously underwent lumbar spine surgeries.: Design: Retrospective analysis of a national database.: Setting: U.S. hospitals.: Patients: ...

    Abstract Study objective: To analyze the use of neuraxial techniques in total hip or knee arthroplasty patients who previously underwent lumbar spine surgeries.
    Design: Retrospective analysis of a national database.
    Setting: U.S. hospitals.
    Patients: Patients undergoing a total hip or knee arthroplasty, stratified by those with a previous lumbar fusion or decompression procedure.
    Measurements: Our primary outcome was the use of neuraxial anesthesia; secondary outcomes included combined complications, cardio-pulmonary complications, and prolonged length of stay. Patients with and without a history of a lumbar procedure were compared using mixed-effects regression.
    Main results: Among 758,857 THAs 8961 had a history of lumbar fusion and 8599 of decompression. Among 1,387,335 TKAs 15,827 had a history of lumbar fusion and 13,652 of decompression. History of a lumbar fusion was associated with lower odds of neuraxial anesthesia use in THA (OR: 0.74 CI: 0.70-0.79, p ≤0.0001) and TKA (OR: 0.80 CI: 0.77-0.84, p ≤0.0001).
    Conclusions: Previous lumbar fusion -but not decompression- surgery is associated with lower neuraxial anesthesia in THA/TKA patients, despite its use being universally associated with decreased length of stay. More research is needed to address the importance of neuraxial techniques in patients with prior spine surgery.
    MeSH term(s) Humans ; Retrospective Studies ; Arthroplasty, Replacement, Hip/adverse effects ; Arthroplasty, Replacement, Hip/methods ; Arthroplasty, Replacement, Knee/adverse effects ; Arthroplasty, Replacement, Knee/methods ; Anesthesia, General/adverse effects ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology
    Language English
    Publishing date 2023-07-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2023.111222
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