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  1. Article ; Online: An Upper Bound Visualization of Design Trade-Offs in Adsorbent Materials for Gas Separations: CO

    Edens, Samuel J / McGrath, Michael J / Guo, Siyu / Du, Zijuan / Zhou, Hemin / Zhong, Lingshan / Shi, Zuhao / Wan, Jieshuo / Bennett, Thomas D / Qiao, Ang / Tao, Haizheng / Li, Neng / Cowan, Matthew G

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 10, Issue 8, Page(s) e2206437

    Abstract: The last 20 years have seen many publications investigating porous solids for gas adsorption and separation. The abundance of adsorbent materials (this work identifies 1608 materials for ... ...

    Abstract The last 20 years have seen many publications investigating porous solids for gas adsorption and separation. The abundance of adsorbent materials (this work identifies 1608 materials for CO
    Language English
    Publishing date 2023-01-16
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202206437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Follow-Up Study of Lung Function and Chest Computed Tomography at 6 Months after Discharge in Patients with Coronavirus Disease 2019.

    Wu, Qian / Zhong, Lingshan / Li, Hongwei / Guo, Jing / Li, Yajie / Hou, Xinwei / Yang, Fangfei / Xie, Yi / Li, Li / Xing, Zhiheng

    Canadian respiratory journal

    2021  Volume 2021, Page(s) 6692409

    Abstract: We aimed to investigate changes in pulmonary function and computed tomography (CT) findings in patients with coronavirus disease 2019 (COVID-19) during the recovery period. COVID-19 patients underwent symptom assessment, pulmonary function tests, and ... ...

    Abstract We aimed to investigate changes in pulmonary function and computed tomography (CT) findings in patients with coronavirus disease 2019 (COVID-19) during the recovery period. COVID-19 patients underwent symptom assessment, pulmonary function tests, and high-resolution chest CT 6 months after discharge from the hospital. Of the 54 patients enrolled, 31 and 23 were in the moderate and severe group, respectively. The main symptoms 6 months after discharge were fatigue and exertional dyspnea, experienced by 24.1% and 18.5% of patients, respectively, followed by smell and taste dysfunction (9.3%) and cough (5.6%). One patient dropped out of the pulmonary function tests. Of the remaining 54 patients, 41.5% had pulmonary dysfunction. Specifically, 7.5% presented with restrictive ventilatory dysfunction (forced vital capacity <80% of the predicted value), 18.9% presented with small airway dysfunction, and 32.1% presented with pulmonary diffusion impairment (diffusing capacity for carbon monoxide <80% of the predicted value). Of the 54 patients enrolled, six patients dropped out of the chest CT tests. Eleven of the remaining 48 patients presented with abnormal lung CT findings 6 months after discharge. Patients with residual lung lesions were more common in the severe group (52.6%) than in the moderate group (3.4%); a higher proportion of patients had involvement of both lungs (42.1% vs. 3.4%) in the severe group. The residual lung lesions were mainly ground-glass opacities (20.8%) and linear opacities (14.6%). Semiquantitative visual scoring of the CT findings revealed significantly higher scores in the left, right, and both lungs in the severe group than in the moderate group. COVID-19 patients 6 months after discharge mostly presented with fatigue and exertional dyspnea, and their pulmonary dysfunction was mostly characterized by pulmonary diffusion impairment. As revealed by chest CT, the severe group had a higher prevalence of residual lesions than the moderate group, and the residual lesions mostly manifested as ground-glass opacities and linear opacities.
    MeSH term(s) Adult ; Aged ; COVID-19/diagnostic imaging ; COVID-19/physiopathology ; Cough/physiopathology ; Dyspnea/physiopathology ; Fatigue/physiopathology ; Female ; Follow-Up Studies ; Forced Expiratory Volume ; Humans ; Lung/diagnostic imaging ; Lung/physiopathology ; Male ; Middle Aged ; Olfaction Disorders/physiopathology ; Peak Expiratory Flow Rate ; Pulmonary Diffusing Capacity ; Recovery of Function ; Respiratory Function Tests ; SARS-CoV-2 ; Severity of Illness Index ; Taste Disorders/physiopathology ; Tomography, X-Ray Computed ; Vital Capacity
    Language English
    Publishing date 2021-02-13
    Publishing country Egypt
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1213103-9
    ISSN 1916-7245 ; 1198-2241
    ISSN (online) 1916-7245
    ISSN 1198-2241
    DOI 10.1155/2021/6692409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Analysis of Chest CT Results of Coronavirus Disease 2019 (COVID-19) Patients at First Follow-Up.

    Zhong, Lingshan / Zhang, Shuo / Wang, Jigang / Zhao, Xinqian / Wang, Kai / Ding, Wenlong / Xing, Zhiheng / Shen, Jun

    Canadian respiratory journal

    2020  Volume 2020, Page(s) 5328267

    Abstract: Objective: To investigate the dissipation and outcomes of pulmonary lesions at the first follow-up of patients who recovered from moderate and severe cases of COVID-19.: Methods: From January 21 to March 3, 2020, a total of 136 patients with COVID-19 ...

    Abstract Objective: To investigate the dissipation and outcomes of pulmonary lesions at the first follow-up of patients who recovered from moderate and severe cases of COVID-19.
    Methods: From January 21 to March 3, 2020, a total of 136 patients with COVID-19 were admitted to our hospital. According to inclusion and exclusion criteria, 52 patients who recovered from COVID-19 were included in this study, including 33 moderate cases and 19 severe cases. Three senior radiologists independently and retrospectively analyzed the chest CT imaging data of 52 patients at the last time of admission and the first follow-up after discharge, including primary manifestations, concomitant manifestations, and degree of residual lesion dissipation.
    Results: At the first follow-up after discharge, 16 patients with COVID-19 recovered to normal chest CT appearance, while 36 patients still had residual pulmonary lesions, mainly including 33 cases of ground-glass opacity, 5 cases of consolidation, and 19 cases of fibrous strip shadow. The proportion of residual pulmonary lesions in severe cases (17/19) was statistically higher than in moderate cases (19/33) (
    Conclusion: Clinically cured patients with COVID-19 had faster dissipation of residual pulmonary lesions after discharge, while moderate patients had better dissipation than severe patients. However, at the first follow-up, most patients still had residual pulmonary lesions, which were primarily ground-glass opacity and fibrous strip shadow. The proportion of residual pulmonary lesions was higher in severe cases of COVID-19, which required further follow-up.
    MeSH term(s) Adult ; Aftercare ; Aged ; COVID-19/diagnostic imaging ; COVID-19/therapy ; COVID-19 Testing/methods ; Female ; Follow-Up Studies ; Hospitalization ; Humans ; Lung/diagnostic imaging ; Male ; Middle Aged ; Multidetector Computed Tomography ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index
    Keywords covid19
    Language English
    Publishing date 2020-11-01
    Publishing country Egypt
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1213103-9
    ISSN 1916-7245 ; 1198-2241
    ISSN (online) 1916-7245
    ISSN 1198-2241
    DOI 10.1155/2020/5328267
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Distinguishing nontuberculous mycobacteria from Mycobacterium tuberculosis lung disease from CT images using a deep learning framework.

    Wang, Li / Ding, Wenlong / Mo, Yan / Shi, Dejun / Zhang, Shuo / Zhong, Lingshan / Wang, Kai / Wang, Jigang / Huang, Chencui / Zhang, Shu / Ye, Zhaoxiang / Shen, Jun / Xing, Zhiheng

    European journal of nuclear medicine and molecular imaging

    2021  Volume 48, Issue 13, Page(s) 4293–4306

    Abstract: Purpose: To develop and evaluate the effectiveness of a deep learning framework (3D-ResNet) based on CT images to distinguish nontuberculous mycobacterium lung disease (NTM-LD) from Mycobacterium tuberculosis lung disease (MTB-LD).: Method: Chest CT ... ...

    Abstract Purpose: To develop and evaluate the effectiveness of a deep learning framework (3D-ResNet) based on CT images to distinguish nontuberculous mycobacterium lung disease (NTM-LD) from Mycobacterium tuberculosis lung disease (MTB-LD).
    Method: Chest CT images of 301 with NTM-LD and 804 with MTB-LD confirmed by pathogenic microbiological examination were retrospectively collected. The differences between the clinical manifestations of the two diseases were analysed. 3D-ResNet was developed to randomly extract data in an 8:1:1 ratio for training, validating, and testing. We also collected external test data (40 with NTM-LD and 40 with MTB-LD) for external validation of the model. The activated region of interest was evaluated using a class activation map. The model was compared with three radiologists in the test set.
    Result: Patients with NTM-LD were older than those with MTB-LD, patients with MTB-LD had more cough, and those with NTM-LD had more dyspnoea, and the results were statistically significant (p < 0.05). The AUCs of our model on training, validating, and testing datasets were 0.90, 0.88, and 0.86, respectively, while the AUC on the external test set was 0.78. Additionally, the performance of the model was higher than that of the radiologist, and without manual labelling, the model automatically identified lung areas with abnormalities on CT > 1000 times more effectively than the radiologists.
    Conclusion: This study shows the efficacy of 3D-ResNet as a rapid auxiliary diagnostic tool for NTB-LD and MTB-LD. Its use can help provide timely and accurate treatment strategies to patients with these diseases.
    MeSH term(s) Deep Learning ; Diagnosis, Differential ; Humans ; Lung Diseases/diagnostic imaging ; Mycobacterium tuberculosis ; Nontuberculous Mycobacteria ; Retrospective Studies ; Tomography, X-Ray Computed ; Tuberculosis/diagnostic imaging
    Language English
    Publishing date 2021-06-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 8236-3
    ISSN 1619-7089 ; 0340-6997 ; 1619-7070
    ISSN (online) 1619-7089
    ISSN 0340-6997 ; 1619-7070
    DOI 10.1007/s00259-021-05432-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1227: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Analysis of Chest CT Results of Coronavirus Disease 2019 (COVID-19) Patients at First Follow-Up

    Zhong, Lingshan / Zhang, Shuo / Wang, Jigang / Zhao, Xinqian / Wang, Kai / Ding, Wenlong / Xing, Zhiheng / Shen, Jun

    Can Respir J

    Abstract: Objective: To investigate the dissipation and outcomes of pulmonary lesions at the first follow-up of patients who recovered from moderate and severe cases of COVID-19. Methods: From January 21 to March 3, 2020, a total of 136 patients with COVID-19 were ...

    Abstract Objective: To investigate the dissipation and outcomes of pulmonary lesions at the first follow-up of patients who recovered from moderate and severe cases of COVID-19. Methods: From January 21 to March 3, 2020, a total of 136 patients with COVID-19 were admitted to our hospital. According to inclusion and exclusion criteria, 52 patients who recovered from COVID-19 were included in this study, including 33 moderate cases and 19 severe cases. Three senior radiologists independently and retrospectively analyzed the chest CT imaging data of 52 patients at the last time of admission and the first follow-up after discharge, including primary manifestations, concomitant manifestations, and degree of residual lesion dissipation. Results: At the first follow-up after discharge, 16 patients with COVID-19 recovered to normal chest CT appearance, while 36 patients still had residual pulmonary lesions, mainly including 33 cases of ground-glass opacity, 5 cases of consolidation, and 19 cases of fibrous strip shadow. The proportion of residual pulmonary lesions in severe cases (17/19) was statistically higher than in moderate cases (19/33) (χ 2 = 5.759, P < 0.05). At the first follow-up, residual pulmonary lesions were dissipated to varying degrees in 47 cases, and lesions remained unchanged in 5 cases. There were no cases of increased numbers of lesions, enlargement of lesions, or appearance of new lesions. The dissipation of residual pulmonary lesions in moderate patients was statistically better than in severe patients (Z = -2.538, P < 0.05). Conclusion: Clinically cured patients with COVID-19 had faster dissipation of residual pulmonary lesions after discharge, while moderate patients had better dissipation than severe patients. However, at the first follow-up, most patients still had residual pulmonary lesions, which were primarily ground-glass opacity and fibrous strip shadow. The proportion of residual pulmonary lesions was higher in severe cases of COVID-19, which required further follow-up.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #926979
    Database COVID19

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  6. Article ; Online: Machine Learning-Based Differentiation of Nontuberculous Mycobacteria Lung Disease and Pulmonary Tuberculosis Using CT Images.

    Xing, Zhiheng / Ding, Wenlong / Zhang, Shuo / Zhong, Lingshan / Wang, Li / Wang, Jigang / Wang, Kai / Xie, Yi / Zhao, Xinqian / Li, Nan / Ye, Zhaoxiang

    BioMed research international

    2020  Volume 2020, Page(s) 6287545

    Abstract: An increasing number of patients infected with nontuberculous mycobacteria (NTM) are observed worldwide. However, it is challenging to identify NTM lung diseases from pulmonary tuberculosis (PTB) due to considerable overlap in classic manifestations and ... ...

    Abstract An increasing number of patients infected with nontuberculous mycobacteria (NTM) are observed worldwide. However, it is challenging to identify NTM lung diseases from pulmonary tuberculosis (PTB) due to considerable overlap in classic manifestations and clinical and radiographic characteristics. This study quantifies both cavitary and bronchiectasis regions in CT images and explores a machine learning approach for the differentiation of NTM lung diseases and PTB. It involves 116 patients and 103 quantitative features. After the selection of informative features, a linear support vector machine performs disease classification, and simultaneously, discriminative features are recognized. Experimental results indicate that bronchiectasis is relatively more informative, and two features are figured out due to promising prediction performance (area under the curve, 0.84 ± 0.06; accuracy, 0.85 ± 0.06; sensitivity, 0.88 ± 0.07; and specificity, 0.80 ± 0.12). This study provides insight into machine learning-based identification of NTM lung diseases from PTB, and more importantly, it makes early and quick diagnosis of NTM lung diseases possible that can facilitate lung disease management and treatment planning.
    MeSH term(s) Adult ; Aged ; Bronchiectasis/diagnostic imaging ; Bronchiectasis/pathology ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Lung/diagnostic imaging ; Machine Learning ; Male ; Middle Aged ; Mycobacterium Infections, Nontuberculous/classification ; Mycobacterium Infections, Nontuberculous/diagnostic imaging ; Mycobacterium Infections, Nontuberculous/pathology ; Nontuberculous Mycobacteria ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods ; Tuberculosis, Pulmonary/classification ; Tuberculosis, Pulmonary/diagnostic imaging ; Tuberculosis, Pulmonary/pathology
    Language English
    Publishing date 2020-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2020/6287545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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