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  1. Article ; Online: Gender inequities in ENT: Insights from women speakers at American Head and Neck Society meetings.

    McKeon, Mallory / Zhou, Anna / Tang, Alice L

    Head & neck

    2024  Volume 46, Issue 6, Page(s) 1406–1416

    Abstract: Background: Gender inequity exists across national speakers at American Head and Neck Society (AHNS) conferences. This qualitative study explores potential causes of this disparity by surveying women invited to speak at AHNS between 2007 and 2019 and ... ...

    Abstract Background: Gender inequity exists across national speakers at American Head and Neck Society (AHNS) conferences. This qualitative study explores potential causes of this disparity by surveying women invited to speak at AHNS between 2007 and 2019 and examining advice, resources, and meaningful actions from "those who made it."
    Methods: An internet search for contact information for the 131 female AHNS was performed. An electronic survey was distributed via email. Deidentified qualitative responses were coded by two independent researchers into themes. Themes characterize barriers that female head and neck (HN) surgeons face and describe ways to mitigate the impact of these for the next generation.
    Results: Contact information for 73/131 female AHNS speakers was obtained via internet search. Email responses were received from 22/73 (30%). Of those, respondents specialized in otolaryngology (n = 17), medical oncology (n = 2), palliative care (n = 1), vascular surgery (n = 1), and thoracic surgical oncology (n = 1). All speakers worked in academic settings at varying stages of their career with 81.8% (18/22) of respondents fellowship-trained (primarily HN surgery). Concerns about gender disparity in ENT were grouped into the following themes: (1) recruiting women to ENT, (2) removing barriers to career advancement, (3) diversifying ENT's national presence, and (4) improving the broader culture of HN surgery. Respondents emphasized a need for diversifying leadership, early exposure to otolaryngology in medical school, and connecting students with female role models. Outstanding research, involvement at annual meetings, and committee membership were consistently deemed important for establishing a national presence in the field. Implicit bias, "boys clubs" culture, and burdensome childcare responsibilities were described as barriers to career advancement.
    Conclusions: While encouraging more women to enter otolaryngology residencies, increasing the number female role models and establishing strong mentoring networks may help to mitigate challenges. Meaningful progress requires the efforts of both male and female allies within the specialty. Simple solutions, such as educating on implicit bias, removing demographics from applications, and eliminating hidden penalties for maternity leave, may help improve diversity and mitigate barriers to career progression for underrepresented groups within ENT.
    MeSH term(s) Humans ; Female ; United States ; Otolaryngology ; Societies, Medical ; Sexism ; Congresses as Topic ; Physicians, Women/statistics & numerical data ; Qualitative Research ; Surveys and Questionnaires
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Aging with my family: a grounded theory approach on the role of family when aging as foreign-born.

    Zhou, Anna / Hellström, Ingrid / Roos, Susanne / Ranada, Åsa Larsson

    BMC geriatrics

    2024  Volume 24, Issue 1, Page(s) 45

    Abstract: Background: Research indicates that it is the quality of the closest relationships in the mixture of social relations that matters most for older adults. For older foreign-born, especially those who migrate late in life, the family is often the only ... ...

    Abstract Background: Research indicates that it is the quality of the closest relationships in the mixture of social relations that matters most for older adults. For older foreign-born, especially those who migrate late in life, the family is often the only socioeconomical resource they can lean on. This study aims to explore how older foreign-born perceive the role of family as they age.
    Methods: The study design has a grounded theory approach. Data consist of individual open-ended interviews with 15 foreign-born informants aged between 60 and 85 years old who migrated to Sweden as adults from various parts of the world.
    Results: The findings demonstrate that family was an essential part of the informants' lives as they lived for their families and their families lived for them. Family solidarity was described as a cultural heritage they took over from their original families and a cultural heritage they wished to pass on to their future generations. They found that this was what separated them as foreign-born from native-born. Memories of their parents reminded them of their biological, social, and cultural heritages. The intimate relationship with their spouses in a life course had served as a source of validation of their individual identities and promoted personal growth and self-esteem. The role as a loving and caring parent entailed a sense of accomplishment and satisfaction for the life lived. And now as grandparents, the role as a link between the family's historical heritage and the future generation entailed not only a sense of coherence as they aged but also hope and meaning beyond their own lives.
    Conclusions: The older foreign-born experienced life satisfaction as they aged with their families. Family meant community and solidarity. It was in the family that they found their distinct roles that had defined them. Family was an indispensable part of their social identity. The findings highlight the importance of older foreign-born being studied from a family and lifetime perspective.
    MeSH term(s) Humans ; Aged ; Aged, 80 and over ; Grounded Theory ; Aging ; Internationality ; Personal Satisfaction ; Research Design
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-023-04641-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Trajectories of internalizing symptoms in early childhood: Associations with maternal internalizing symptoms and child physiology.

    Zhou, Anna M / Buss, Kristin A

    Developmental psychobiology

    2021  Volume 63, Issue 5, Page(s) 1295–1308

    Abstract: Research has shown that children's internalizing symptom development during early childhood are shaped by biopsychosocial processes including physiology and parental symptoms. However, associations between maternal internalizing symptoms, child ... ...

    Abstract Research has shown that children's internalizing symptom development during early childhood are shaped by biopsychosocial processes including physiology and parental symptoms. However, associations between maternal internalizing symptoms, child physiology and trajectories of child internalizing symptoms are not well understood. We used growth curve models to examine how maternal internalizing symptoms, child physiology and the interaction between maternal internalizing symptoms and child physiology may be associated with trajectories of internalizing symptoms during early childhood. Mothers reported their children's internalizing symptoms when children were 3, 4, 5 and 6 years of age, and mothers self-reported their own internalizing symptoms when children were 3. Respiratory Sinus Arrhythmia (RSA) was collected when children were 3.5-years-old. Results showed that there is a non-linear, quadratic trajectory across all participants from age 3 to 6. Maternal internalizing symptoms were not associated with children's internalizing symptoms at age 6, but were associated with both linear and quadratic change. Lower resting RSA was associated with greater increases in children's internalizing symptoms over time. Interactions between maternal internalizing symptoms and RSA were not associated with children's internalizing symptom development. The findings demonstrate that maternal internalizing symptoms and child physiology are independently associated with internalizing symptom development during early childhood.
    MeSH term(s) Child ; Child, Preschool ; Depression/psychology ; Female ; Humans ; Mothers/psychology ; Parents ; Respiratory Sinus Arrhythmia/physiology
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 4107-5
    ISSN 1098-2302 ; 0012-1630
    ISSN (online) 1098-2302
    ISSN 0012-1630
    DOI 10.1002/dev.22104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Multimodality Approach to Lymphedema Surgery Achieves and Maintains Normal Limb Volumes: A Treatment Algorithm to Optimize Outcomes.

    Deptula, Peter / Zhou, Anna / Posternak, Victoria / He, Hui / Nguyen, Dung

    Journal of clinical medicine

    2022  Volume 11, Issue 3

    Abstract: Surgical treatment of advanced lymphedema is challenging and outcomes are suboptimal. Physiologic procedures including lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) improve lymphatic flow but cannot reverse fibrofatty ... ...

    Abstract Surgical treatment of advanced lymphedema is challenging and outcomes are suboptimal. Physiologic procedures including lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) improve lymphatic flow but cannot reverse fibrofatty tissue deposition, whereas liposuction removes fibrofatty tissue but cannot prevent disease progression. The adjunctive use of nanofibrillar collagen scaffolds (BioBridge
    Language English
    Publishing date 2022-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11030598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The invisibilization of Asian American women psychologists in academia: A Call to Action.

    Lau, Nancy / Zhou, Anna M / Zhao, Xin / Ng, Mei Yi / Suyemoto, Karen L

    The Behavior therapist

    2023  Volume 45, Issue 3, Page(s) 99–106

    Abstract: In light of recent escalations in violence and discrimination against members of the Asian American community, it is important to raise awareness about and increase visibility of academic and social inequities that Asian American women psychologists face ...

    Abstract In light of recent escalations in violence and discrimination against members of the Asian American community, it is important to raise awareness about and increase visibility of academic and social inequities that Asian American women psychologists face and provide strategies for increasing support. This call to action describes a framework for understanding racism as it applies to the unique intersectional experiences of Asian American women psychologists in the United States and inequities faced at the macro and micro levels. We provide concrete recommendations for institutions and individuals to develop and enhance DEI initiatives to counteract the processes and barriers that serve to exclude, marginalize, and invisibilize Asian American women psychologists.
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747035-0
    ISSN 0278-8403
    ISSN 0278-8403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Racial disparities among candidemic patients at a Southern California teaching hospital.

    Grant, Victoria C / Zhou, Anna Y / Tan, Karen K / Abdul-Mutakabbir, Jacinda C

    Infection control and hospital epidemiology

    2023  Volume 44, Issue 11, Page(s) 1866–1869

    Abstract: Racially and ethnically minoritized (REM) patients are disproportionately affected by infectious diseases, including candidemia. REM patients with candidemia were significantly younger, with trends toward more risk factors for candidemia and longer ... ...

    Abstract Racially and ethnically minoritized (REM) patients are disproportionately affected by infectious diseases, including candidemia. REM patients with candidemia were significantly younger, with trends toward more risk factors for candidemia and longer lengths of stay. Although
    MeSH term(s) Humans ; Candidemia/epidemiology ; Candida ; Candidiasis/drug therapy ; Hospitals, Teaching ; Risk Factors ; Antifungal Agents/therapeutic use ; Retrospective Studies
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2023.74
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Place in Therapy of Cyclin-Dependent Kinase 4/6 Inhibitors in Breast Cancer: A Targeted Literature Review.

    Zhao, Melody / Hanson, Kent A / Zhang, Yixie / Zhou, Anna / Cha-Silva, Ashley S

    Targeted oncology

    2023  Volume 18, Issue 3, Page(s) 327–358

    Abstract: Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are the preferred regimen for patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced or metastatic breast cancer. However, the optimal ... ...

    Abstract Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are the preferred regimen for patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced or metastatic breast cancer. However, the optimal treatment sequencing for CDK4/6i with other available therapeutic options is unclear. We conducted a targeted literature review to identify the current evidence on CDK4/6i treatment patterns in patients with breast cancer. The search was initially conducted in October 2021 and subsequently updated in October 2022. Biomedical databases and gray literature were searched, and bibliographies of included reviews were screened for relevant studies. The search identified ten reviews published since 2021 and 87 clinical trials or observational studies published since 2015. The included reviews discussed CDK4/6i usage with or without endocrine therapy (ET) in first-line and second-line treatment for patients with HR+/HER2- advanced or metastatic breast cancer, followed by ET, chemotherapy, or targeted therapy with ET. Clinical studies reported similar treatment sequences consisting of ET, chemotherapy, or targeted therapy with ET prior to CDK4/6i with ET, followed by ET monotherapy, chemotherapy, targeted therapy with ET, or continued CDK4/6i with ET. Current evidence suggests CDK4/6i are effective for HR+/HER2- advanced or metastatic breast cancer in earlier lines of therapy. Efficacy of CDK4/6i as measured by progression-free survival and overall survival was similar within a line of therapy regardless of the type of prior therapy. Survival on different post-CDK4/6i treatments was also similar within the same line of therapy. Additional research is needed to investigate the optimal place in therapy of CDK4/6i and the sequencing of treatments following progression on CDK4/6i.
    MeSH term(s) Humans ; Female ; Breast Neoplasms/pathology ; Cyclin-Dependent Kinase 4 ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Progression-Free Survival ; Cyclin-Dependent Kinase 6 ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Receptor, ErbB-2/metabolism
    Chemical Substances Cyclin-Dependent Kinase 4 (EC 2.7.11.22) ; Protein Kinase Inhibitors ; Cyclin-Dependent Kinase 6 (EC 2.7.11.22) ; Receptor, ErbB-2 (EC 2.7.10.1)
    Language English
    Publishing date 2023-04-19
    Publishing country France
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2222136-0
    ISSN 1776-260X ; 1776-2596
    ISSN (online) 1776-260X
    ISSN 1776-2596
    DOI 10.1007/s11523-023-00957-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clinical Presentation, Management, and Diagnostic Performance of 2021 Criteria for Paraneoplastic Neurologic Syndromes in Childhood.

    Zhou, Ji / Jin, Mei / Su, Yan / Zhuo, Xiuwei / Fu, Libing / Ren, Xiaotun / Ren, Changhong / Zhou, Anna / Li, Jiuwei / Zhang, Weihua

    Neurology(R) neuroimmunology & neuroinflammation

    2024  Volume 11, Issue 3, Page(s) e200242

    Abstract: Background and objectives: Paraneoplastic neurologic syndromes (PNSs) are remote neurologic immune-related effects of tumors. The clinical characteristics of pediatric PNSs remain unclear. We retrospectively examined the clinical characteristics of ... ...

    Abstract Background and objectives: Paraneoplastic neurologic syndromes (PNSs) are remote neurologic immune-related effects of tumors. The clinical characteristics of pediatric PNSs remain unclear. We retrospectively examined the clinical characteristics of cases of pediatric PNSs and assessed the performance of the 2021 diagnostic criteria in children.
    Methods: Patients hospitalized in the Beijing Children's Hospital between June 2015 and June 2023 and fulfilling the description of
    Results: Among the 42 patients included, the most common neurologic syndrome was opsoclonus-myoclonus syndrome (OMS) (62%), followed by rapidly progressive cerebellar syndrome (26%). Most tumors were neuroblastomas (88%), with few being ovarian teratomas (10%). Approximately 71% (30/42) of patients were classified as definite and 24% (10/42) as
    Discussion: OMS followed by rapidly progressive cerebellar ataxia are the most common forms of PNSs in children and are associated with neuroblastoma. An aggressive approach with multiple immunotherapies may improve the prognosis of neuroblastoma-associated PNSs. The 2021 criteria perform well in pediatric PNSs. However, we propose upgrading the classification of antibody-negative rapidly progressive cerebellar ataxia with neuroblastoma to definite diagnosis. This adjustment aims to further improve the diagnostic efficacy of this diagnostic criterion in childhood.
    MeSH term(s) Humans ; Female ; Male ; Retrospective Studies ; Child, Preschool ; Child ; Paraneoplastic Syndromes, Nervous System/diagnosis ; Paraneoplastic Syndromes, Nervous System/immunology ; Paraneoplastic Syndromes, Nervous System/therapy ; Infant ; Opsoclonus-Myoclonus Syndrome/diagnosis ; Opsoclonus-Myoclonus Syndrome/etiology ; Opsoclonus-Myoclonus Syndrome/drug therapy ; Adolescent ; Neuroblastoma/complications ; Neuroblastoma/diagnosis
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2767740-0
    ISSN 2332-7812 ; 2332-7812
    ISSN (online) 2332-7812
    ISSN 2332-7812
    DOI 10.1212/NXI.0000000000200242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Interactions among stress, behavioral inhibition, and delta-beta coupling predict adolescent anxiety during the COVID-19 pandemic.

    Ramos, Michelle L / Zhou, Anna M / Lytle, Marisa N / Myruski, Sarah / Pérez-Edgar, Koraly / Buss, Kristin A

    Developmental psychobiology

    2024  Volume 66, Issue 3, Page(s) e22485

    Abstract: The COVID-19 pandemic brought about unprecedented changes and uncertainty to the daily lives of youth. The range of adjustment in light of a near-universal experience of COVID restrictions highlights the importance of identifying factors that may render ... ...

    Abstract The COVID-19 pandemic brought about unprecedented changes and uncertainty to the daily lives of youth. The range of adjustment in light of a near-universal experience of COVID restrictions highlights the importance of identifying factors that may render some individuals more susceptible to heightened levels of anxiety during stressful life events than others. Two risk factors to consider are temperamental behavioral inhibition (BI) and difficulties in emotion regulation (ER). As such, the current paper focused on BI examined prior to COVID, because of its developmental link to anxiety and ER, as difficulties may be associated with differences in anxiety. We examined a neurocognitive marker of ER processes, delta-beta coupling (DBC). The current paper had two goals: (1) to examine BI in relation to COVID-related worry and social anxiety experienced during the pandemic, and (2) to explore the role of individual differences in early DBC in the relationship between BI and anxiety outcomes 6 months apart during COVID-19 (n = 86; T1 M
    MeSH term(s) Humans ; Adolescent ; Pandemics ; COVID-19 ; Anxiety/psychology ; Anxiety Disorders ; Fear
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4107-5
    ISSN 1098-2302 ; 0012-1630
    ISSN (online) 1098-2302
    ISSN 0012-1630
    DOI 10.1002/dev.22485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Autonomic nervous system activity moderates associations between temperament and externalizing behaviors in early childhood.

    Zhou, Anna M / Morales, Santiago / Youatt, Elizabeth A / Buss, Kristin A

    Developmental psychobiology

    2022  Volume 64, Issue 7, Page(s) e22323

    Abstract: Temperamental risk, such as surgency, negative affect, and poor effortful control, has been posited as a predictor of externalizing symptom development. However, autonomic nervous system (ANS) activity underlying processes of reactivity and regulation ... ...

    Abstract Temperamental risk, such as surgency, negative affect, and poor effortful control, has been posited as a predictor of externalizing symptom development. However, autonomic nervous system (ANS) activity underlying processes of reactivity and regulation may moderate associations between early temperament and later externalizing behaviors during early childhood. The aim of the present study was to examine how interactions between resting sympathetic (SNS) and parasympathetic (PNS) activity at age 5 may moderate associations between temperamental risk at age 3 and externalizing behavior at age 6 (n = 87). Results demonstrate different interactions between resting ANS activity and temperamental risk to predict externalizing behaviors. For children with lower SNS activation at rest, surgency was positively associated with externalizing behaviors. Negative affect was positively associated with externalizing behaviors except when there were either high levels of SNS and PNS activity or low levels of SNS and PNS activity. Effortful control was not associated with externalizing behaviors, though SNS and PNS activity interacted to predict externalizing behaviors after accounting for effortful control. Taken together, the results highlight the importance to examine multisystem resting physiological activity as a moderator of associations between temperamental risk and the development of externalizing  behaviors.
    MeSH term(s) Child ; Humans ; Child, Preschool ; Temperament/physiology ; Autonomic Nervous System ; Child Behavior Disorders ; Parasympathetic Nervous System
    Language English
    Publishing date 2022-10-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 4107-5
    ISSN 1098-2302 ; 0012-1630
    ISSN (online) 1098-2302
    ISSN 0012-1630
    DOI 10.1002/dev.22323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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