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  1. Article ; Online: Response to Letter to the Editor Regarding the Article "Contrast-Enhanced Ultrasound Liver Imaging Reporting and Data System in Diagnosing Hepatocellular Carcinoma: Diagnostic Performance and Interobserver Agreement" by Zhou and Collaborators.

    Zhou, Hang / Huang, Pintong

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)

    2023  Volume 44, Issue 6, Page(s) 652–653

    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnostic imaging ; Liver Neoplasms/diagnostic imaging ; Observer Variation ; Ultrasonography/methods
    Language English
    Publishing date 2023-04-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 1439-0914 ; 1431-4894 ; 0172-4614
    ISSN (online) 1438-8782
    ISSN 1439-0914 ; 1431-4894 ; 0172-4614
    DOI 10.1055/a-1979-0808
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intracellular magnesium optimizes transmission efficiency and plasticity of hippocampal synapses by reconfiguring their connectivity.

    Zhou, Hang / Bi, Guo-Qiang / Liu, Guosong

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 3406

    Abstract: Synapses at dendritic branches exhibit specific properties for information processing. However, how the synapses are orchestrated to dynamically modify their properties, thus optimizing information processing, remains elusive. Here, we observed at ... ...

    Abstract Synapses at dendritic branches exhibit specific properties for information processing. However, how the synapses are orchestrated to dynamically modify their properties, thus optimizing information processing, remains elusive. Here, we observed at hippocampal dendritic branches diverse configurations of synaptic connectivity, two extremes of which are characterized by low transmission efficiency, high plasticity and coding capacity, or inversely. The former favors information encoding, pertinent to learning, while the latter prefers information storage, relevant to memory. Presynaptic intracellular Mg
    MeSH term(s) Animals ; Magnesium/metabolism ; Synapses/physiology ; Synapses/metabolism ; Hippocampus/physiology ; Hippocampus/metabolism ; Neuronal Plasticity/physiology ; Dendrites/physiology ; Dendrites/metabolism ; Synaptic Transmission/physiology ; Male ; Memory/physiology ; Rats ; Learning/physiology ; Mice ; Mice, Inbred C57BL
    Chemical Substances Magnesium (I38ZP9992A)
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-47571-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Alcohol Use and Use Disorder and Cancer Risk: Perspective on Causal Inference.

    Zhou, Hang / Vasiliou, Vasilis

    Complex psychiatry

    2022  Volume 8, Issue 1-2, Page(s) 9–12

    Language English
    Publishing date 2022-08-09
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 3021167-0
    ISSN 2673-298X ; 2673-3005
    ISSN (online) 2673-298X
    ISSN 2673-3005
    DOI 10.1159/000526407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Chronic lymphocytic leukemia/small lymphocytic lymphoma arising in the pituitary gland: illustrative case.

    Zhou, Hang / Zhang, Xiaowei / Jia, Xin / Jia, Liang / Zhang, Qingjiu

    Journal of neurosurgery. Case lessons

    2024  Volume 7, Issue 10

    Abstract: Background: The authors describe a 60-year-old female who underwent a correlative examination for an accidental scalp injury, revealing a sellar mass, which was surgically excised and pathologically confirmed to be a non-Hodgkin's small B-cell lymphoma. ...

    Abstract Background: The authors describe a 60-year-old female who underwent a correlative examination for an accidental scalp injury, revealing a sellar mass, which was surgically excised and pathologically confirmed to be a non-Hodgkin's small B-cell lymphoma. These findings in combination with the immunophenotype led to a final diagnosis of chronic lymphocytic leukemia/small lymphocytic lymphoma. Previous studies have shown that hematological solid tumors occurring in the pituitary gland are extremely rare, and there are only approximately three other cases of living patients with similarities to this case, all of which had ambiguous expression of subsequent hematological treatment.
    Observations: In this case, the authors used an endoscopic approach to completely excise the tumor. Follow-up of the patient was continued after surgery, and the patient is currently receiving standardized treatment with zanubrutinib.
    Lessons: This patient did not have any previous history of tumor, had a good postoperative recovery with a normal quality of life, and still receives hormone replacement and zanubrutinib on a standardized basis. This is a complete case that has not been previously reported and reveals the diagnostic and therapeutic process of rare diseases in the sellar area.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 2694-1902
    ISSN (online) 2694-1902
    DOI 10.3171/CASE23773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Multi-ancestry Whole-exome Sequencing Study of Alcohol Use Disorder in Two Cohorts.

    Wang, Lu / Kranzler, Henry R / Gelernter, Joel / Zhou, Hang

    medRxiv : the preprint server for health sciences

    2024  

    Abstract: Alcohol use disorder (AUD) is a leading cause of death and disability worldwide. There has been substantial progress in identifying genetic variants underlying AUD. However, there are few whole-exome sequencing (WES) studies of AUD. We analyzed WES of 4, ... ...

    Abstract Alcohol use disorder (AUD) is a leading cause of death and disability worldwide. There has been substantial progress in identifying genetic variants underlying AUD. However, there are few whole-exome sequencing (WES) studies of AUD. We analyzed WES of 4,530 samples from the Yale-Penn cohort and 469,835 samples from the UK Biobank (UKB). After quality control, 1,420 AUD cases and 619 controls of European ancestry (EUR) and 1,142 cases and 608 controls of African ancestry (AFR) from Yale-Penn were retained for subsequent analyses. WES data from 415,617 EUR samples (12,861 cases), 6,142 AFR samples (130 cases) and 4,607 South Asian (SAS) samples (130 cases) from UKB were also analyzed. Single-variant association analysis identified the well-known functional variant rs1229984 in
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.04.05.24305412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Development of generic metabolic Raman calibration models using solution titration in aqueous phase and data augmentation for in-line cell culture analysis.

    Zhang, Zhijun / Lang, Zhe / Chen, Gong / Zhou, Hang / Zhou, Weichang

    Biotechnology and bioengineering

    2024  

    Abstract: This study presents a novel approach for developing generic metabolic Raman calibration models for in-line cell culture analysis using glucose and lactate stock solution titration in an aqueous phase and data augmentation techniques. First, a successful ... ...

    Abstract This study presents a novel approach for developing generic metabolic Raman calibration models for in-line cell culture analysis using glucose and lactate stock solution titration in an aqueous phase and data augmentation techniques. First, a successful set-up of the titration method was achieved by adding glucose or lactate solution at several different constant rates into the aqueous phase of a bench-top bioreactor. Subsequently, the in-line glucose and lactate concentration were calculated and interpolated based on the rate of glucose and lactate addition, enabling data augmentation and enhancing the robustness of the metabolic calibration model. Nine different combinations of spectra pretreatment, wavenumber range selection, and number of latent variables were evaluated and optimized using aqueous titration data as training set and a historical cell culture data set as validation and prediction set. Finally, Raman spectroscopy data collected from 11 historical cell culture batches (spanning four culture modes and scales ranging from 3 to 200 L) were utilized to predict the corresponding glucose and lactate values. The results demonstrated a high prediction accuracy, with an average root mean square errors of prediction of 0.65 g/L for glucose, and 0.48 g/L for lactate. This innovative method establishes a generic metabolic calibration model, and its applicability can be extended to other metabolites, reducing the cost of deploying real-time cell culture monitoring using Raman spectroscopy in bioprocesses.
    Language English
    Publishing date 2024-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280318-5
    ISSN 1097-0290 ; 0006-3592
    ISSN (online) 1097-0290
    ISSN 0006-3592
    DOI 10.1002/bit.28717
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Evolution and Future Trends of Stromal Vascular Fraction: A Bibliometric Analysis.

    Liu, Yang / Huang, Hai / Zhou, Hang / Yuan, Yifeng / Shi, Xiaolin

    Tissue engineering. Part C, Methods

    2024  Volume 30, Issue 4, Page(s) 143–158

    Abstract: The heterogeneous population of cells obtained from processed adipose tissue, known as stromal vascular fraction (SVF), exhibits immunomodulatory and angiogenic properties. The therapeutic efficacy of SVF has been substantiated in numerous diseases, ... ...

    Abstract The heterogeneous population of cells obtained from processed adipose tissue, known as stromal vascular fraction (SVF), exhibits immunomodulatory and angiogenic properties. The therapeutic efficacy of SVF has been substantiated in numerous diseases, instilling hope for its clinical application as a cellular therapy. This study aims to provide a comprehensive analysis of the scholarly literature on SVF, including its worldwide progression, highlighting significant literatures, temporal development, research clusters, current active topics, and emerging trends. The combination of CiteSpace, HistCite Pro, and VOS Viewer tools was used to analyze the SVF literature. The overall panorama of the field is elucidated in terms of publication count, timeline, institutional distribution, journal coverage, and authors' contributions. In addition, this analysis explores the literature and keywords through the lens of co-occurrence, citation, and co-citation frequencies. Clustering algorithms are used to track the trajectory of the literature further, providing insight into its development. The findings offer a comprehensive overview of the progress made in the SVF field, highlighting distinct phases of development: the "Seedling period" from 1980 to 2010, the "Panicle period" from 2011 to 2016, and the "Flowering period" from 2017 to 2023. Within these periods, the evolution of 10 clusters is unraveled, encompassing topics such as vascular disease, CD34 expression, adipose tissue macrophage in 2013, cell-assisted lipotransfer, and knee osteoarthritis. In summary, this bibliometric study, conducting a quantitative analysis of publications in SVF research, encompasses a global overview of research, an analysis of pivotal literature in the field, research hotspots, and emerging frontiers.
    MeSH term(s) Adipose Tissue ; Algorithms ; Bibliometrics ; Immunomodulation ; Macrophages
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2420585-0
    ISSN 1937-3392 ; 1937-3384
    ISSN (online) 1937-3392
    ISSN 1937-3384
    DOI 10.1089/ten.TEC.2023.0310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Near-Infrared Fluorescent Probe for the Rapid Detection of Nitroxyl in Living Cells.

    Zhou, Hang / Jin, Yu / Wang, Sheng / Wang, Yixiang / Bu, Ming

    Journal of fluorescence

    2024  

    Abstract: Nitroxyl (HNO) plays an important role in various physiological activities. It has the potential to be used as a treatment for certain diseases such as alcohol poisoning, acute hypertension, and atherosclerosis. However, traditional methods for detecting ...

    Abstract Nitroxyl (HNO) plays an important role in various physiological activities. It has the potential to be used as a treatment for certain diseases such as alcohol poisoning, acute hypertension, and atherosclerosis. However, traditional methods for detecting HNO are challenging due to its rapid polymerization and elimination into N
    Language English
    Publishing date 2024-03-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2016892-5
    ISSN 1573-4994 ; 1053-0509
    ISSN (online) 1573-4994
    ISSN 1053-0509
    DOI 10.1007/s10895-024-03637-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Level-k Thinking in the Extensive Form

    Schipper, Burkhard C. / Zhou, Hang

    2023  

    Abstract: Level-$k$ thinking and Cognitive Hierarchy have been widely applied as a normal-form solution concept in behavioral and experimental game theory. We consider level-k thinking in games in extensive form. Player's may learn about levels of opponents' ... ...

    Abstract Level-$k$ thinking and Cognitive Hierarchy have been widely applied as a normal-form solution concept in behavioral and experimental game theory. We consider level-k thinking in games in extensive form. Player's may learn about levels of opponents' thinking during the play of the game because some information sets may be inconsistent with certain levels. In particular, for any information set reached, a level-$k$ player attaches the maximum level-$\ell$ thinking for $\ell < k$ to her opponents consistent with the information set. We compare our notion of strong level-$k$ thinking with other solution concepts such as level-$k$ thinking in the associated normal form, strong rationalizability, $\Delta$-rationalizability, iterated admissibility, backward rationalizability, backward level-$k$ thinking, and backward induction. We use strong level-$k$ thinking to reanalyze data from some prior experiments in the literature.

    Comment: 50 pages, 10 figures
    Keywords Computer Science - Computer Science and Game Theory
    Publishing date 2023-11-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Book ; Online: Euclidean Capacitated Vehicle Routing in Random Setting

    Nie, Zipei / Zhou, Hang

    A $1.55$-Approximation Algorithm

    2023  

    Abstract: We study the unit-demand capacitated vehicle routing problem in the random setting of the Euclidean plane. The objective is to visit $n$ random terminals in a square using a set of tours of minimum total length, such that each tour visits the depot and ... ...

    Abstract We study the unit-demand capacitated vehicle routing problem in the random setting of the Euclidean plane. The objective is to visit $n$ random terminals in a square using a set of tours of minimum total length, such that each tour visits the depot and at most $k$ terminals. We design an elegant algorithm combining the classical sweep heuristic and Arora's framework for the Euclidean traveling salesman problem [Journal of the ACM 1998]. We show that our algorithm is a polynomial-time approximation of ratio at most $1.55$ asymptotically almost surely. This improves on previous approximation ratios of $1.995$ due to Bompadre, Dror, and Orlin [Journal of Applied Probability 2007] and $1.915$ due to Mathieu and Zhou [Random Structures and Algorithms 2022]. In addition, we conjecture that, for any $\varepsilon>0$, our algorithm is a $(1+\varepsilon)$-approximation asymptotically almost surely.

    Comment: 21 pages, 0 figures
    Keywords Computer Science - Data Structures and Algorithms
    Subject code 629
    Publishing date 2023-04-21
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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