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  1. Article ; Online: Effects of intestinal Desulfovibrio bacteria on host health and its potential regulatory strategies: A review.

    Zhou, Heyi / Huang, Dandan / Sun, Zetong / Chen, Xiaoyong

    Microbiological research

    2024  Volume 284, Page(s) 127725

    Abstract: Increasing studies have focused on the relationship between Desulfovibrio bacteria (DSV) and host health in recent years. However, little is known about the mechanisms by which DSV affects host health and the strategies to accurately regulate DSV numbers. ...

    Abstract Increasing studies have focused on the relationship between Desulfovibrio bacteria (DSV) and host health in recent years. However, little is known about the mechanisms by which DSV affects host health and the strategies to accurately regulate DSV numbers. This review mainly presents the relationship between DSV and host health, potential modulatory strategies, and the potential mechanisms affecting host health. Evidence suggests that DSV can both promote host health and induce the occurrence and development of disease, and these effects are closely related to its metabolites (e.g., H
    MeSH term(s) Desulfovibrio/metabolism ; Desulfovibrio/physiology ; Humans ; Probiotics ; Gastrointestinal Microbiome/physiology ; Biofilms/growth & development ; Intestines/microbiology ; Prebiotics ; Animals ; Fatty Acids, Volatile/metabolism ; Hydrogen Sulfide/metabolism ; Diet
    Language English
    Publishing date 2024-04-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1189614-0
    ISSN 1618-0623 ; 0944-5013
    ISSN (online) 1618-0623
    ISSN 0944-5013
    DOI 10.1016/j.micres.2024.127725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Thoughts on Construction of Information System of Medical Device Variety Archives].

    Ma, Jin / Guo, Yuanyuan / Wang, Chao / Zhou, Heyi

    Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation

    2021  Volume 45, Issue 3, Page(s) 310–314

    Abstract: Objective: Thinking on the construction of the medical device type archives information system.: Methods: This paper introduces the concept and significance of medical device variety archives, and puts forward the overall construction idea and system ...

    Abstract Objective: Thinking on the construction of the medical device type archives information system.
    Methods: This paper introduces the concept and significance of medical device variety archives, and puts forward the overall construction idea and system framework of medical device variety archives by analyzing its construction difficulties.
    Results: Considering the long-term nature and complexity of the construction of medical device variety archives, the system can be constructed in accordance with the three steps of system building, platform building and data management, and the overall technical architecture can be designed from the eight aspects of user layer, business application layer, application support layer, data resource layer, infrastructure layer, security, standards and operation and maintenance management.
    Conclusions: Architecture design is the foundation of system construction, and its design rationality is very important for the success of system construction. The architecture design proposed in this study has a certain reference role for promoting the construction of medical device variety archives management system.
    MeSH term(s) Information Systems ; Reference Standards
    Language Chinese
    Publishing date 2021-06-07
    Publishing country China
    Document type Journal Article
    ISSN 1671-7104
    ISSN 1671-7104
    DOI 10.3969/j.issn.1671-7104.2021.03.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Modification of chitosan grafted with collagen peptide by enzyme crosslinking.

    Hu, Wanqing / Liu, Meng / Yang, Xiaoshuang / Zhang, Chang / Zhou, Heyi / Xie, Weiguo / Fan, Lihong / Nie, Min

    Carbohydrate polymers

    2018  Volume 206, Page(s) 468–475

    Abstract: Free radicals are closely related to the occurrence and development of aging, cancer and inflammation. In this paper, the microbial transglutaminase (MTGase) was used as a catalyst to graft the collagen peptide (COP) molecules on the amino group of ... ...

    Abstract Free radicals are closely related to the occurrence and development of aging, cancer and inflammation. In this paper, the microbial transglutaminase (MTGase) was used as a catalyst to graft the collagen peptide (COP) molecules on the amino group of carboxymethyl chitosan sulfate (CMCS) to improve the antioxidant effects. FT-IR and NMR spectroscopy were used to confirm the successful grafting of COP to CMCS. Degree of substitution (DS) of CMCS-COP could be controlled by adjusting the reaction conditions. With the increase of concentration, the ability of each sample on scavenging capacity and reducibility tends to increase obviously. The results of anticoagulant experiments showed that the ability of CMCS and CMCS-COP with three different degrees of substitution on activated partial thrombin time (APTT) and prothrombin time (PT) values were all increased to compare with the control group. No relevant cytotoxicity against NIH-3T3 mouse fibroblasts was found for the copolymers. These results suggested that CMCS-COP would appear to be a promising candidate for wound dressing application.
    MeSH term(s) Animals ; Anticoagulants/chemical synthesis ; Anticoagulants/chemistry ; Anticoagulants/pharmacology ; Anticoagulants/toxicity ; Bandages ; Chitosan/analogs & derivatives ; Chitosan/chemical synthesis ; Chitosan/chemistry ; Chitosan/pharmacology ; Chitosan/toxicity ; Collagen/chemical synthesis ; Collagen/chemistry ; Collagen/pharmacology ; Collagen/toxicity ; Free Radical Scavengers/chemical synthesis ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/pharmacology ; Free Radical Scavengers/toxicity ; Mice ; Molecular Structure ; NIH 3T3 Cells ; Oxidation-Reduction ; Partial Thromboplastin Time ; Peptide Fragments/chemical synthesis ; Peptide Fragments/chemistry ; Peptide Fragments/pharmacology ; Peptide Fragments/toxicity ; Prothrombin Time ; Temperature ; Transglutaminases/chemistry
    Chemical Substances Anticoagulants ; Free Radical Scavengers ; O-carboxymethylchitosan ; Peptide Fragments ; Collagen (9007-34-5) ; Chitosan (9012-76-4) ; Transglutaminases (EC 2.3.2.13)
    Language English
    Publishing date 2018-10-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2018.09.023
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  4. Article ; Online: Different B-type methionine sulfoxide reductases in Chlamydomonas may protect the alga against high-light, sulfur-depletion, or oxidative stress.

    Zhao, Lei / Chen, Mei / Cheng, Dongmei / Yang, Haomeng / Sun, Yongle / Zhou, Heyi / Huang, Fang

    Journal of integrative plant biology

    2013  Volume 55, Issue 11, Page(s) 1054–1068

    Abstract: The genome of unicellular green alga Chlamydomonas reinhardtii contains four genes encoding B-type methionine sulfoxide reductases, MSRB1.1, MSRB1.2, MSRB2.1, and MSRB2.2, with functions largely unknown. To understand the cell defense system mediated by ... ...

    Abstract The genome of unicellular green alga Chlamydomonas reinhardtii contains four genes encoding B-type methionine sulfoxide reductases, MSRB1.1, MSRB1.2, MSRB2.1, and MSRB2.2, with functions largely unknown. To understand the cell defense system mediated by the methionine sulfoxide reductases in Chlamydomonas, we analyzed expression and physiological roles of the MSRBs under different abiotic stress conditions using immunoblotting and quantitative polymerase chain reaction (PCR) analyses. We showed that the MSRB2.2 protein was accumulated in cells treated with high light (1,300 µE/m² per s), whereas MSRB1.1 was accumulated in the cells under 1 mmol/L H₂O₂ treatment or sulfur depletion. We observed that the cells with the MSRB2.2 knockdown and overexpression displayed increased and decreased sensitivity to high light, respectively, based on in situ chlorophyll a fluorescence measures. We also observed that the cells with the MSRB1.1 knockdown and overexpression displayed decreased and increased tolerance to sulfur-depletion and oxidative stresses, respectively, based on growth and H₂-producing performance. The physiological implications revealed from the experimental data highlight the importance of MSRB2.2 and MSRB1.1 in protecting Chlamydomonas cells against adverse conditions such as high-light, sulfur-depletion, and oxidative stresses.
    MeSH term(s) Antibody Formation ; Chlamydomonas/drug effects ; Chlamydomonas/enzymology ; Chlamydomonas/genetics ; Chlamydomonas/radiation effects ; Gene Expression Profiling ; Gene Expression Regulation, Plant/drug effects ; Gene Expression Regulation, Plant/radiation effects ; Hydrogen Peroxide/pharmacology ; Light ; Methionine Sulfoxide Reductases/chemistry ; Methionine Sulfoxide Reductases/genetics ; Methionine Sulfoxide Reductases/metabolism ; Oxidative Stress/drug effects ; Oxidative Stress/radiation effects ; Phenotype ; Plants, Genetically Modified ; Sequence Analysis, Protein ; Stress, Physiological/radiation effects ; Sulfur/deficiency
    Chemical Substances Sulfur (70FD1KFU70) ; Hydrogen Peroxide (BBX060AN9V) ; Methionine Sulfoxide Reductases (EC 1.8.4.-)
    Language English
    Publishing date 2013-11
    Publishing country China (Republic : 1949- )
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2130095-1
    ISSN 1744-7909 ; 1672-9072
    ISSN (online) 1744-7909
    ISSN 1672-9072
    DOI 10.1111/jipb.12104
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