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  1. Book ; Online: PromptNER

    Zhang, Mozhi / Yan, Hang / Zhou, Yaqian / Qiu, Xipeng

    A Prompting Method for Few-shot Named Entity Recognition via k Nearest Neighbor Search

    2023  

    Abstract: Few-shot Named Entity Recognition (NER) is a task aiming to identify named entities via limited annotated samples. Recently, prototypical networks have shown promising performance in few-shot NER. Most of prototypical networks will utilize the entities ... ...

    Abstract Few-shot Named Entity Recognition (NER) is a task aiming to identify named entities via limited annotated samples. Recently, prototypical networks have shown promising performance in few-shot NER. Most of prototypical networks will utilize the entities from the support set to construct label prototypes and use the query set to compute span-level similarities and optimize these label prototype representations. However, these methods are usually unsuitable for fine-tuning in the target domain, where only the support set is available. In this paper, we propose PromptNER: a novel prompting method for few-shot NER via k nearest neighbor search. We use prompts that contains entity category information to construct label prototypes, which enables our model to fine-tune with only the support set. Our approach achieves excellent transfer learning ability, and extensive experiments on the Few-NERD and CrossNER datasets demonstrate that our model achieves superior performance over state-of-the-art methods.

    Comment: work in progress
    Keywords Computer Science - Computation and Language
    Subject code 410
    Publishing date 2023-05-20
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: AC-Bipolar Electropolymerization of 3,4-Ethylenedioxythiophene in Ionic Liquids.

    Chen, Zhenghao / Zhou, Yaqian / Villani, Elena / Shida, Naoki / Tomita, Ikuyoshi / Inagi, Shinsuke

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 12, Page(s) 4450–4455

    Abstract: Recently, alternating current (AC)-bipolar electropolymerization of 3,4-ethylenedioxythiophene (EDOT) has been reported to produce poly(3,4-ethylenedioxythiophene) (PEDOT) fibers from the terminals of bipolar electrodes in acetonitrile solution (MeCN) ... ...

    Abstract Recently, alternating current (AC)-bipolar electropolymerization of 3,4-ethylenedioxythiophene (EDOT) has been reported to produce poly(3,4-ethylenedioxythiophene) (PEDOT) fibers from the terminals of bipolar electrodes in acetonitrile solution (MeCN) containing low concentrations of supporting salts in a template-free manner. Here, we extend such methodology in ionic liquid (IL) media. Three kinds of ILs, diethylmethyl(2-methoxyethyl)ammonium tetrafluoroborate ([DEME][BF
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c00120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Male Sex Is Not a Risk Factor for Prognosis in Postoperative Thyroid Cancer Patients: A Propensity Score Matching Study.

    Zhou, Yaqian / Wang, Yan / Zhang, Zhiting / Yin, Xue / Liu, Jianjun / Zheng, Wei

    The Journal of clinical endocrinology and metabolism

    2023  Volume 108, Issue 12, Page(s) 3330–3337

    Abstract: Purpose: To study whether male sex is a risk factor for prognosis in patients with differentiated thyroid cancer after 131I treatment using the propensity score matching (PSM) method.: Methods: From April 2016 to October 2021, 1948 postoperative ... ...

    Abstract Purpose: To study whether male sex is a risk factor for prognosis in patients with differentiated thyroid cancer after 131I treatment using the propensity score matching (PSM) method.
    Methods: From April 2016 to October 2021, 1948 postoperative differentiated thyroid cancer patients aged 43 (interquartile range: 34, 54) years who received 131I treatment were retrospectively enrolled and divided into male (n = 645) and female groups (n = 1303). The PSM method was adopted to process all data to reduce the influence of data bias and confounding variables. The Mann-Whitney U test and χ2 test were used for data analysis. Multivariate logistic regression was used to analyze the risk factors affecting prognosis, and the receiver operating characteristic curve was used to analyze the relationship between stimulated thyroglobulin (sTg) level, 131I dose, and poor prognosis.
    Results: Before PSM, the proportion of male patients with poor prognosis was significantly higher than that of female patients. After PSM, there was no difference in the proportion of poor prognosis between male and female groups. Multivariate logistic regression analysis showed that male sex; high T stage, N1b stage, and M1 stage; high sTg level; and high 131I dose were risk factors for poor prognosis before PSM. After PSM, high T stage, M1 stage, high sTg level, and 131I dose were still risk factors but male sex was no longer a risk factor for poor prognosis.
    Conclusions: After the reduction of selection bias by PSM, male sex was no longer a risk factor for prognosis after 131I treatment of differentiated thyroid cancer. In addition, high T stage (T3 + T4 stage), M1 stage, sTg ≥10.15 ng/mL, and 131I dose ≥260 mCi were risk factors for poor prognosis.
    MeSH term(s) Humans ; Male ; Female ; Iodine Radioisotopes/therapeutic use ; Retrospective Studies ; Propensity Score ; Thyroid Neoplasms/epidemiology ; Thyroid Neoplasms/radiotherapy ; Thyroid Neoplasms/surgery ; Thyroglobulin ; Prognosis ; Adenocarcinoma/drug therapy ; Risk Factors
    Chemical Substances Iodine-131 ; Iodine Radioisotopes ; Thyroglobulin (9010-34-8)
    Language English
    Publishing date 2023-05-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgad314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Fabrication of Gradient and Patterned Organic Thin Films by Bipolar Electrolytic Micelle Disruption Using Redox-Active Surfactants.

    Zhou, Yaqian / Shida, Naoki / Tomita, Ikuyoshi / Inagi, Shinsuke

    Angewandte Chemie (International ed. in English)

    2021  Volume 60, Issue 26, Page(s) 14620–14629

    Abstract: Bipolar electrochemistry could be regarded as a powerful approach for selective surface modification due to the beneficial feature that a wirelessly controllable potential distribution on bipolar electrodes (BPEs). Herein we report a bipolar electrolytic ...

    Abstract Bipolar electrochemistry could be regarded as a powerful approach for selective surface modification due to the beneficial feature that a wirelessly controllable potential distribution on bipolar electrodes (BPEs). Herein we report a bipolar electrolytic micelle disruption (BEMD) system for the preparation of shaped organic films. A U-shaped bipolar electrolytic system with a sigmoidal potential gradient on the BPE gave gradient-thin films including various interesting organic compounds, such as a polymerizable monomer, an organic pigment and aggregation induced emission (AIE) molecules. The gradient feature was characterized by UV-Vis absorption, thickness measurements and surface morphology analysis. Corresponding patterned films were also fabricated using a cylindrical bipolar electrolytic setup that enables site-selective application of the potential on the BPE. Such a facile BEMD approach will open a long-term perspective with respect to organic film preparation.
    Language English
    Publishing date 2021-05-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202103233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Electrochemiluminescence aptasensing method for ultrasensitive determination of lipopolysaccharide based on CRISPR-Cas12a accessory cleavage activity.

    Shi, Jiayue / Li, Sijia / Shao, Rongguang / Jiang, Yang / Qiao, Yanxia / Liu, Jin / Zhou, Yaqian / Li, Yan

    Talanta

    2024  Volume 272, Page(s) 125828

    Abstract: In this study, an ultrasensitive electrochemiluminescence (ECL) aptasensing method was developed for lipopolysaccharide (LPS) determination based on CRISPR-Cas12a accessory cleavage activity. Tris (2,2'-bipyridine) dichlororuthenium (II) (Ru(bpy) ...

    Abstract In this study, an ultrasensitive electrochemiluminescence (ECL) aptasensing method was developed for lipopolysaccharide (LPS) determination based on CRISPR-Cas12a accessory cleavage activity. Tris (2,2'-bipyridine) dichlororuthenium (II) (Ru(bpy)
    MeSH term(s) Humans ; Lipopolysaccharides ; DNA, Single-Stranded ; Gold ; Metal Nanoparticles ; CRISPR-Cas Systems ; Luminescent Measurements/methods ; Sulfhydryl Compounds ; Biosensing Techniques/methods ; Electrochemical Techniques/methods ; Fluorocarbon Polymers
    Chemical Substances perfluorosulfonic acid (39464-59-0) ; Lipopolysaccharides ; DNA, Single-Stranded ; Gold (7440-57-5) ; Sulfhydryl Compounds ; Fluorocarbon Polymers
    Language English
    Publishing date 2024-02-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2024.125828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: SpeechAgents

    Zhang, Dong / Li, Zhaowei / Wang, Pengyu / Zhang, Xin / Zhou, Yaqian / Qiu, Xipeng

    Human-Communication Simulation with Multi-Modal Multi-Agent Systems

    2024  

    Abstract: Human communication is a complex and diverse process that not only involves multiple factors such as language, commonsense, and cultural backgrounds but also requires the participation of multimodal information, such as speech. Large Language Model (LLM)- ...

    Abstract Human communication is a complex and diverse process that not only involves multiple factors such as language, commonsense, and cultural backgrounds but also requires the participation of multimodal information, such as speech. Large Language Model (LLM)-based multi-agent systems have demonstrated promising performance in simulating human society. Can we leverage LLM-based multi-agent systems to simulate human communication? However, current LLM-based multi-agent systems mainly rely on text as the primary medium. In this paper, we propose SpeechAgents, a multi-modal LLM based multi-agent system designed for simulating human communication. SpeechAgents utilizes multi-modal LLM as the control center for individual agent and employes multi-modal signals as the medium for exchanged messages among agents. Additionally, we propose Multi-Agent Tuning to enhance the multi-agent capabilities of LLM without compromising general abilities. To strengthen and evaluate the effectiveness of human communication simulation, we build the Human-Communication Simulation Benchmark. Experimental results demonstrate that SpeechAgents can simulate human communication dialogues with consistent content, authentic rhythm, and rich emotions and demonstrate excellent scalability even with up to 25 agents, which can apply to tasks such as drama creation and audio novels generation. Code and models will be open-sourced at https://github. com/0nutation/SpeechAgents

    Comment: work in progress
    Keywords Computer Science - Computation and Language
    Subject code 006
    Publishing date 2024-01-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Homogeneous Electrochemiluminescence for Highly Sensitive Determination of Demethylase FTO Based on Target-Regulated DNAzyme Cleavage and Host–Guest Interaction

    Yang, Xia / Qiao, Shuai / Zhao, Wei / Li, Sijia / Qiao, Yanxia / Jiang, Yang / Zhou, Yaqian / Li, Yan

    Analytical Chemistry. 2023 July 24, v. 95, no. 30 p.11420-11428

    2023  

    Abstract: Fat mass and obesity-associated protein (FTO) is the first reported N⁶-methyladenosine (m⁶A) RNA demethylase. The dysregulation of FTO demethylation is strongly associated with various human cancers in a m⁶A-dependent manner. Herein, a homogeneous ... ...

    Abstract Fat mass and obesity-associated protein (FTO) is the first reported N⁶-methyladenosine (m⁶A) RNA demethylase. The dysregulation of FTO demethylation is strongly associated with various human cancers in a m⁶A-dependent manner. Herein, a homogeneous electrochemiluminescence (ECL) method for the determination of FTO was proposed based on the target-regulated DNAzyme cleavage. Moreover, the ECL signal was highly enhanced by host–guest interaction between β-cyclodextrin (β-CD) and tri-n-propylamine (TPrA). The m⁶A caged DNAzyme 17E-Me acted as a padlock, while the FTO served as the corresponding key. As the key, FTO could specifically remove m⁶A modification, restoring the cleavage activity of DNAzyme 17E. With the assistance of the Zn²⁺ cofactor, the substrate strand was cleaved at a specific site, and the ECL indicator of Ru­(phen)₃ ²⁺ was discharged to produce an ECL signal. On the contrary, 17E-Me was blocked and no cleavage reaction occurred without the key. For the ECL detection, the electrode modification of β-CD@AuNPs concentrated Ru­(phen)₃ ²⁺ species through electrostatic adsorption and gathered TPrA molecules through host–guest interaction with β-CD, which resulted in an intense ECL response. The results demonstrated the ECL intensity linearly correlated with the logarithm of the FTO concentration (from 0.0001 to 100 nM) with a low detection limit (30 fM). The IC₅₀ value for FTO inhibitors rhein and meclofenamic acid were 35.6 μM and 20.3 μM, respectively. The strategy was further validated for FTO detection in MCF-7 cell lysates and Hela cell lysates. This work reveals that this strategy is promising for developing homogeneous ECL method for detection of FTO and screening of the demethylase inhibitors.
    Keywords RNA ; adsorption ; analytical chemistry ; demethylation ; detection limit ; electrochemiluminescence ; electrodes ; human cell lines ; humans
    Language English
    Dates of publication 2023-0724
    Size p. 11420-11428.
    Publishing place American Chemical Society
    Document type Article ; Online
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c01661
    Database NAL-Catalogue (AGRICOLA)

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  8. Book ; Online: DUB

    Zhang, Dong / Ye, Rong / Ko, Tom / Wang, Mingxuan / Zhou, Yaqian

    Discrete Unit Back-translation for Speech Translation

    2023  

    Abstract: How can speech-to-text translation (ST) perform as well as machine translation (MT)? The key point is to bridge the modality gap between speech and text so that useful MT techniques can be applied to ST. Recently, the approach of representing speech with ...

    Abstract How can speech-to-text translation (ST) perform as well as machine translation (MT)? The key point is to bridge the modality gap between speech and text so that useful MT techniques can be applied to ST. Recently, the approach of representing speech with unsupervised discrete units yields a new way to ease the modality problem. This motivates us to propose Discrete Unit Back-translation (DUB) to answer two questions: (1) Is it better to represent speech with discrete units than with continuous features in direct ST? (2) How much benefit can useful MT techniques bring to ST? With DUB, the back-translation technique can successfully be applied on direct ST and obtains an average boost of 5.5 BLEU on MuST-C En-De/Fr/Es. In the low-resource language scenario, our method achieves comparable performance to existing methods that rely on large-scale external data. Code and models are available at https://github.com/0nutation/DUB.

    Comment: Accepted to Findings of ACL 2023
    Keywords Computer Science - Computation and Language ; Computer Science - Sound ; Electrical Engineering and Systems Science - Audio and Speech Processing
    Subject code 410
    Publishing date 2023-05-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Investigation of scale inhibition effect and mechanism of S-HGMF in the clean recirculating cooling water system

    Zhao, Xin / Li, Suqin / Li, Yongkui / Guo, Penghui / Zhou, Yaqian / Zhao, Zekun / Cai, Yinshi

    Science of the total environment. 2022 Nov. 01, v. 845

    2022  

    Abstract: The formation of scales in a recirculating water system is a common problem in industrial water treatment; it seriously affects the production in various industries and pollutes the environment. Although conventional scale inhibition methods are ... ...

    Abstract The formation of scales in a recirculating water system is a common problem in industrial water treatment; it seriously affects the production in various industries and pollutes the environment. Although conventional scale inhibition methods are effective, they are expensive and harm the environment. Herein, an advanced method is proposed to solve the scaling issue in recirculating cooling water systems using the superconducting high-gradient magnetic field (S-HGMF) treatment. The scale inhibition performance could be improved by changing the magnetic flux density, operation time, and flow rate. The results showed that S-HGMF could increase the number of hydrogen bonds in the recirculating cooling water, enhance molecular interaction, increase the thickness of the ion hydration shell, reduce the nucleation rate, stabilize the water quality, improve the solubility of scale-forming ions, and inhibit scale formation. The scale inhibition performance reached 8.10%. Interestingly, S-HGMF had a memory effect in that it could maintain the scale inhibition effect for some period after treatment completion. Moreover, S-HGMF changed the crystal structure of the scale and promoted the transformation of the scale to a metastable phase. Ultimately, calcite was transformed to aragonite to reduce the precipitation of hard scale (calcite), achieving the purpose of scale inhibition. As a physical method, the application of S-HGMF to inhibit scaling has great potential for industrial applications.
    Keywords aragonite ; calcite ; crystal structure ; environment ; hydrogen ; magnetic fields ; solubility ; water quality ; water treatment
    Language English
    Dates of publication 2022-1101
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.157156
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Cost Function Determination for Human Lifting Motion

    Tang, Biwei / Peng, Yaling / Luo, Jing / Zhou, Yaqian / Pang, Muye / Xiang, Kui

    Frontiers in bioengineering and biotechnology

    2022  Volume 10, Page(s) 883633

    Abstract: Investigating the optimal control strategy involved in human lifting motion can provide meritorious insights on designing and controlling wearable robotic devices to release human low-back pain and fatigue. However, determining the latent cost function ... ...

    Abstract Investigating the optimal control strategy involved in human lifting motion can provide meritorious insights on designing and controlling wearable robotic devices to release human low-back pain and fatigue. However, determining the latent cost function regarding this motion remains challenging due to the complexities of the human central nervous system. Recently, it has been discovered that the underlying cost function of a biological motion can be identified from an inverse optimization control (IOC) issue, which can be handled
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.883633
    Database MEDical Literature Analysis and Retrieval System OnLINE

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