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  1. Article: [Regulation of ischemic stroke by circadian rhythm and intervention by traditional Chinese medicine].

    Li, Zhong / Liu, Li-Juan / Yan, Si-Yang / Gao, Xiao-Feng / Zeng, Fu-Kang / Zhou, De-Sheng / Zhang, Yu-Xing

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2023  Volume 48, Issue 3, Page(s) 569–578

    Abstract: Circadian rhythm is an internal regulatory mechanism formed in organisms in response to the circadian periodicity in the environment, which modulates the pathophysiological events, occurrence and development of diseases, and the response to treatment in ... ...

    Abstract Circadian rhythm is an internal regulatory mechanism formed in organisms in response to the circadian periodicity in the environment, which modulates the pathophysiological events, occurrence and development of diseases, and the response to treatment in mammals. It significantly influences the susceptibility, injury, and recovery of ischemic stroke, and the response to therapy. Accumulating evidence indicates that circadian rhythms not only regulate the important physiological factors of ischemic stroke events, such as blood pressure and coagulation-fibrinolysis system, but also participate in the immuno-inflammatory reaction mediated by glial cells and peripheral immune cells after ischemic injury and the regulation of neurovascular unit(NVU). This article aims to link molecular, cellular, and physiological pathways in circadian biology to the clinical consequences of ischemic stroke and to illustrate the impact of circadian rhythms on ischemic stroke pathogenesis, the regulation of NVU, and the immuno-inflammatory responses. The regulation of circadian rhythm by traditional Chinese medicine is reviewed, and the research progress of traditional Chinese medicine intervention in circadian rhythm is summarized to provide a reasonable and valuable reference for the follow-up traditional Chinese medicine research and molecular mechanism research of circadian rhythm.
    MeSH term(s) Animals ; Ischemic Stroke ; Medicine, Chinese Traditional ; Circadian Rhythm ; Blood Coagulation ; Blood Pressure ; Mammals
    Language Chinese
    Publishing date 2023-02-03
    Publishing country China
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20221019.601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: On the One-Point Model for the Productivity Evaluation in Jingbian Sector of Yan’an Gas Field

    Liu Er-hu / Liu Yang-yang / Gao Li-jun / Zhou De-sheng / Liu Xiong / Xu Jin-ze

    Frontiers in Earth Science, Vol

    2021  Volume 9

    Abstract: The productivity equation of a gas well is, in the final analysis, an expression that describes the relationship between the production of a gas well and its bottom-hole flowing pressure. There are two kinds of productivity equations in common use at ... ...

    Abstract The productivity equation of a gas well is, in the final analysis, an expression that describes the relationship between the production of a gas well and its bottom-hole flowing pressure. There are two kinds of productivity equations in common use at present: binomial productivity equation and exponential productivity equation. Combined with the modified isochronal well test, the test data are interpreted, and it is found that the open flow rates calculated by the two productivity equations are basically the same when the pressure difference at the test point is large, and the deviation of the exponential productivity equation is large when the pressure difference at the test point is small. Using binomial productivity equation and modifying isochronous well test, we established the single-point deliverability formula for the Jingbian sector of the Yan’an gas field. The field experience formula and production data are used to verify it. Their average errors are 2.59% and 7.12%, respectively; and the coincidence rate of productivity evaluation is 90%. The one-point productivity formula established has high precision and is suitable for productivity analysis of gas wells in paleozoic reservoirs in the Jingbian sector of the Yan’an gas field. This paper provides insights into the one-point productivity evaluation and its future application in the gas field.
    Keywords productivity equation ; gas field ; modified isochronal test ; one-point deliverability formula ; open flow ; Science ; Q
    Subject code 621
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: [Effects of compound danshen tablet on the expression of Abeta in transgenic cell model of Alzheimer's disease].

    Hu, Hua / Zhou, De-sheng / Yu, Rong

    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

    2012  Volume 32, Issue 12, Page(s) 1663–1666

    Abstract: Objective: To study the effects of Compound Danshen Tablet (CDT) on the expression of the beta-amyloid peptide (Abeta) in transgenic cell model of Alzheimer's disease (AD).: Methods: The previously successfully cultured transgenic cell model was used ...

    Abstract Objective: To study the effects of Compound Danshen Tablet (CDT) on the expression of the beta-amyloid peptide (Abeta) in transgenic cell model of Alzheimer's disease (AD).
    Methods: The previously successfully cultured transgenic cell model was used as AD transgenic cell model. Rats were fed with 0.5, 1, 2, and 4 times CDT. The AD transgenic cells were cultured in 0.5, 1, 2, and 4 times rats' sera. The expressions of Abeta in transgenic cells were detected using Western blot.
    Results: The optimal dose effect was obtained in the 1 time CDT group at 24 h.
    Conclusion: CDT could reduce the Abeta expression level in the AD transgenic cell model.
    MeSH term(s) Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Animals ; Cell Line ; Drugs, Chinese Herbal/pharmacology ; Rats ; Rats, Sprague-Dawley ; Salvia miltiorrhiza/chemistry ; Transgenes
    Chemical Substances Amyloid beta-Peptides ; Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2012-12
    Publishing country China
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1195456-5
    ISSN 1003-5370
    ISSN 1003-5370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Spatial Integration of Urban Tourist Center and Tourist Scenic Spot Based on Facility Location Theory

    LU Xiang-lin / MA Yu-qian / GAO Shu-fang / ZHAO Ning / ZHOU De-sheng

    Journal of Chongqing Normal University, Vol 30, Iss 04, Pp 142-

    A Case Study of Shijiazhuang City

    2013  Volume 147

    Abstract: The success of Shanghai tourist centre in China has triggered a climax of constructing urban tourist center. Many cities have established tourist， and researches related to it constantly heating up, become one of the hotspot issues of Chinese tourism ... ...

    Abstract The success of Shanghai tourist centre in China has triggered a climax of constructing urban tourist center. Many cities have established tourist， and researches related to it constantly heating up, become one of the hotspot issues of Chinese tourism academic concern. A model max∑i∈I∑j∈j∑k∈Kairig°ijkxijk that urban tourist centres and tourist scenic spots is constructed which is and the visitor barrier-free traffic transfer problems from the transport hubs to tourist centres are solved based on theory of tourist'ｓ value creation and facility location. The spatial integration of Shijiazhuang City'ｓ tourist centres and tourist scenic spots is taken as a case study to the constructed model, and relevant recommendations are which is: 1) the reasonable sum of Shijiazhuang City'ｓ tourist centres is five; 2) Traffic Link among tourist centres, tourist scenic spots, and related infrastructure facilities needs to strengthen; 3) Pingshan County'ｓ tourist centre should be further strengthened in order to ensure its tourism public service level; 4) Shijiazhuang City'ｓ government need to increase the degree of intervention to its tourist centres and to promote its tourism center'ｓ public service function. Finally, further extensions orientations to our research are proposed.
    Keywords FLP(facility location problem) ; maximal covering ; urban tourist center ; tourist scenic spot ; spatial integration ; Shijiazhuan city ; Science (General) ; Q1-390 ; Science ; Q ; DOAJ:Science (General) ; DOAJ:Science General
    Subject code 910
    Language Chinese
    Publishing date 2013-07-01T00:00:00Z
    Publisher Chongqing Normal University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: [Thinking on the prevention and treatment of myocardial ischemia/reperfusion injury by Chinese medicine therapy of activating blood circulation and removing stasis].

    Hu, Hua / Huang, Zheng-de / Zhou, De-sheng

    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

    2010  Volume 30, Issue 12, Page(s) 1310–1316

    Abstract: In this paper, the theoretical and experimental researches concerning the prevention and treatment of myocardial ischemia/reperfusion (I/R) injury by Chinese medicine (CM) therapy of activating blood circulation and removing stasis in recent five years ... ...

    Abstract In this paper, the theoretical and experimental researches concerning the prevention and treatment of myocardial ischemia/reperfusion (I/R) injury by Chinese medicine (CM) therapy of activating blood circulation and removing stasis in recent five years were reviewed, and the mechanisms were summarized. Thereby, based upon the current development of molecular biology and application of new technology, the authors offered their suggestions on the emphasized points and methods of present CM study in this scope.
    MeSH term(s) Drugs, Chinese Herbal/therapeutic use ; Humans ; Medicine, Chinese Traditional/methods ; Myocardial Ischemia/drug therapy ; Myocardial Reperfusion Injury/drug therapy ; Myocardial Reperfusion Injury/prevention & control ; Phytotherapy
    Chemical Substances Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2010-12
    Publishing country China
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1195456-5
    ISSN 1003-5370
    ISSN 1003-5370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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