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  1. Article: [Effect of HBV DNA load on the safety and prognosis of systematic therapy in advanced hepatocellular carcinoma].

    Zheng, X R / Peng, J X / Song, X / Liu, B / Zhong, C / Chen, X Y / Zhang, B X / Peng, L / Zhu, K S / Xie, C

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 14, Page(s) 1160–1167

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Male ; Middle Aged ; Female ; Carcinoma, Hepatocellular/therapy ; DNA, Viral/analysis ; DNA, Viral/pharmacology ; DNA, Viral/therapeutic use ; Liver Neoplasms/therapy ; Retrospective Studies ; Hepatitis B ; Hepatitis B virus/genetics ; Prognosis ; Antiviral Agents/therapeutic use
    Chemical Substances DNA, Viral ; Antiviral Agents
    Language Chinese
    Publishing date 2024-04-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20231110-01055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Efficacy and safety of anti-PD-1 monoclonal antibody in advanced hepatocellular carcinoma after TACE combined with TKI therapy].

    Xu, Z N / Huang, J J / Zhou, J / Huang, W S / Guo, Y J / Cai, M Y / Zhou, J W / Lin, L T / Liang, L C / Zhu, K S

    Zhonghua nei ke za zhi

    2021  Volume 60, Issue 7, Page(s) 630–636

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Antibodies, Monoclonal/therapeutic use ; Carcinoma, Hepatocellular/drug therapy ; Chemoembolization, Therapeutic ; Enzyme Inhibitors/therapeutic use ; Female ; Humans ; Liver Neoplasms/drug therapy ; Male ; Middle Aged ; Neoplasm Recurrence, Local
    Chemical Substances Antibodies, Monoclonal ; Enzyme Inhibitors
    Language Chinese
    Publishing date 2021-10-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20200928-00841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Effect of febuxostat on epithelial-to-mesenchymal transition of kidney tubules, serum interleukin-6 and transforming growth factor β(1) in hyperuricemic rats].

    Lin, Z M / Zhang, R S / Fan, C X / Liang, Y L / Li, L / Zhao, L / Qu, J C / Xu, X / Zhao, H Y / Liu, X N / Zhu, K S

    Zhonghua nei ke za zhi

    2017  Volume 56, Issue 5, Page(s) 363–367

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Animals ; Cadherins/metabolism ; Chalcone/pharmacology ; Creatinine/blood ; Drugs, Chinese Herbal ; Epithelial-Mesenchymal Transition/drug effects ; Febuxostat/pharmacology ; Gout Suppressants ; Hyperuricemia ; Interleukin-6/blood ; Interleukin-6/metabolism ; Kidney Tubules/drug effects ; Kidney Tubules/metabolism ; Kidney Tubules/pathology ; Male ; Rats ; Rats, Sprague-Dawley ; Transforming Growth Factor beta/metabolism ; Transforming Growth Factor beta/pharmacology ; Transforming Growth Factor beta1 ; Uric Acid
    Chemical Substances CDH1 protein, human ; Cadherins ; Drugs, Chinese Herbal ; Gout Suppressants ; IL6 protein, human ; Interleukin-6 ; TGFB1 protein, human ; Transforming Growth Factor beta ; Transforming Growth Factor beta1 ; Febuxostat (101V0R1N2E) ; Uric Acid (268B43MJ25) ; Chalcone (5S5A2Q39HX) ; Creatinine (AYI8EX34EU)
    Language Chinese
    Publishing date 2017-05-01
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.issn.0578-1426.2017.05.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: 320-detector CT coronary angiography with prospective and retrospective electrocardiogram gating in a single heartbeat: comparison of image quality and radiation dose.

    Qin, J / Liu, L-Y / Fang, Y / Zhu, J-M / Wu, Z / Zhu, K-S / Zhang, J-S / Shan, H

    The British journal of radiology

    2012  Volume 85, Issue 1015, Page(s) 945–951

    Abstract: Objectives: To compare the image quality, radiation dose and diagnostic accuracy of 320-detector CT coronary angiography with prospective and retrospective electrocardiogram (ECG) gating in a single heartbeat.: Methods: Two independent reviewers ... ...

    Abstract Objectives: To compare the image quality, radiation dose and diagnostic accuracy of 320-detector CT coronary angiography with prospective and retrospective electrocardiogram (ECG) gating in a single heartbeat.
    Methods: Two independent reviewers separately scored image quality of coronary artery segment for 480 cardiac CT studies in a prospective group and a retrospective group (240 patients with a heart rate <65 beats per minute in each group). The two groups matched well for clinical characteristics and CT parameters. There was good agreement for image quality scores of coronary artery segment between the independent reviewers (κ=0.73). Of the 7023 coronary artery segments, the image quality scores of the prospective group and retrospective group were not significantly different (p>0.05). The mean radiation dose was 10.0 ± 3.5 mSv (range 6.2-21.6 mSv) for prospective ECG gating at 65-85% of R-R interval (the interval between the R-wave of one heartbeat to the R-wave of the next). The mean radiation dose for retrospective ECG-triggered modulated scans was 23.2 ± 3.4 mSv (range 17-27.4 mSv). The mean radiation dose was 57% lower for prospective gating than for retrospective gating (p<0.01).
    Results: Compared with coronary angiography, the results for prospective vs retrospective ECG gating were 92% vs 90% for sensitivity (p=0.23), 89% vs 91% for specificity (p=0.19), 90% vs 93% for positive predictive value (p=0.25) and 92% vs 95% for negative predictive value (p=0.21) for lesions with ≥50% stenosis, respectively.
    Conclusion: 320-detector CT coronary angiography performed with prospective ECG gating has similar subjective image quality scores, but a 57% lower radiation dose than retrospective ECG gating in a single heartbeat.
    MeSH term(s) Adult ; Aged ; Cardiac-Gated Imaging Techniques/methods ; Coronary Angiography/adverse effects ; Coronary Angiography/methods ; Coronary Disease/diagnosis ; Coronary Disease/diagnostic imaging ; Electrocardiography/methods ; Female ; Heart Rate/physiology ; Humans ; Logistic Models ; Male ; Middle Aged ; Odds Ratio ; Predictive Value of Tests ; Prospective Studies ; Quality Control ; Radiation Dosage ; Radiographic Image Interpretation, Computer-Assisted ; Retrospective Studies ; Risk Assessment ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2012-06-28
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr/29901700
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Status of HVPG clinical application in China in 2021].

    Zhang, W / Liu, F Q / Zhang, L P / Ding, H G / Zhuge, Y Z / Wang, J T / Li, L / Wang, G C / Wu, H / Li, H / Cao, G H / Lu, X F / Kong, D R / Sun, L / Wu, W / Sun, J H / Liu, J T / Zhu, H / Li, D L /
    Guo, W H / Xue, H / Wang, Y / Gengzang, C J C / Zhao, T / Yuan, M / Liu, S R / Huan, H / Niu, M / Li, X / Ma, J / Zhu, Q L / Guo, W W / Zhang, K P / Zhu, X L / Huang, B R / Li, J N / Wang, W D / Yi, H F / Zhang, Q / Gao, L / Zhang, G / Zhao, Z W / Xiong, K / Wang, Z X / Shan, H / Li, M S / Zhang, X Q / Shi, H B / Hu, X G / Zhu, K S / Zhang, Z G / Jiang, H / Zhao, J B / Huang, M S / Shen, W Y / Zhang, L / Xie, F / Li, Z W / Hou, C L / Hu, S J / Lu, J W / Cui, X D / Lu, T / Yang, S S / Liu, W / Shi, J P / Lei, Y M / Bao, J L / Wang, T / Ren, W X / Yu, L / Yu, Q / Xiang, H L / Luo, W W / Qi, X L

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2022  Volume 30, Issue 6, Page(s) 637–643

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) China/epidemiology ; Hepatic Veins ; Humans ; Hypertension, Portal/diagnosis ; Liver Cirrhosis ; Portal Pressure
    Language Chinese
    Publishing date 2022-06-03
    Publishing country China
    Document type Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20220302-00093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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