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  1. Article ; Online: Characteristics and associated factors of health information-seeking behaviour among patients with inflammatory bowel disease in the digital era: a scoping review.

    Ni, Zijun / Zhu, Lingli / Li, Shuyan / Zhang, Yuping / Zhao, Ruiyi

    BMC public health

    2024  Volume 24, Issue 1, Page(s) 307

    Abstract: Background: Health Information-Seeking Behaviour (HISB) is necessary for self-management and medical decision-making among patients with inflammatory bowel disease (IBD). With the advancement of information technology, health information needs and ... ...

    Abstract Background: Health Information-Seeking Behaviour (HISB) is necessary for self-management and medical decision-making among patients with inflammatory bowel disease (IBD). With the advancement of information technology, health information needs and seeking are reshaped among patients with IBD. This scoping review aims to gain a comprehensive understanding of HISB of people with IBD in the digital age.
    Methods: This scoping review adhered to Arksey and O'Malley's framework and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews frameworks (PRISMA-ScR). A comprehensive literature search was conducted in PubMed, Embase, Web of Science, PsycINFO, CINAHL, and three Chinese databases from January 1, 2010 to April 10, 2023. Employing both deductive and inductive content analysis, we scrutinized studies using Wilson's model.
    Results: In total, 56 articles were selected. Within the information dimension of HISB among patients with IBD, treatment-related information, particularly medication-related information, was identified as the most critical information need. Other information requirements included basic IBD-related information, daily life and self-management, sexual and reproductive health, and other needs. In the sources dimension, of the eight common sources of information, the internet was the most frequently mentioned source of information, while face-to-face communication with healthcare professionals was the preferred source. Associated factors were categorized into six categories: demographic characteristics, psychological aspects, role-related or interpersonal traits, environmental aspects, source-related characteristics, and disease-related factors. Moreover, the results showed five types of HISB among people with IBD, including active searching, ongoing searching, passive attention, passive searching, and avoid seeking. Notably, active searching, especially social information seeking, appeared to be the predominant common type of HISB among people with IBD in the digital era.
    Conclusion: Information needs and sources for patients with IBD exhibit variability, and their health information-seeking behaviour is influenced by a combination of diverse factors, including resource-related and individual factors. Future research should focus on the longitudinal changes in HISB among patients with IBD. Moreover, efforts should be made to develop information resources that are both convenient and provide credible information services, although the development of such resources requires further investigation and evaluation.
    MeSH term(s) Humans ; Information Seeking Behavior ; Health Behavior ; Health Personnel ; Inflammatory Bowel Diseases/therapy
    Language English
    Publishing date 2024-01-27
    Publishing country England
    Document type Systematic Review ; Review ; Journal Article
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-024-17758-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Spatiotemporal variations and potential influencing factors of hemorrhagic fever with renal syndrome: A case study in Weihe Basin, China.

    Zhu, Lingli / Lu, Liang / Li, Shujuan / Ren, Hongyan

    PLoS neglected tropical diseases

    2023  Volume 17, Issue 4, Page(s) e0011245

    Abstract: Background: Hemorrhagic fever with renal syndrome (HFRS) is a widespread zoonotic disease seriously threatening Chinese residents' health. HFRS of Weihe Basin remains highly prevalent in recent years and attracts wide attention. With the acceleration of ...

    Abstract Background: Hemorrhagic fever with renal syndrome (HFRS) is a widespread zoonotic disease seriously threatening Chinese residents' health. HFRS of Weihe Basin remains highly prevalent in recent years and attracts wide attention. With the acceleration of urbanization and related environmental changes, the interaction among anthropogenic activities, environmental factors, and host animals becomes more complicated in this area, which posed increasingly complex challenges for implementing effective prevention measures. Identifying the potential influencing factors of continuous HFRS epidemics in this typical area is critical to make targeted prevention and control strategies.
    Methods: Spatiotemporal characteristics of HFRS epidemic were analyzed based on HFRS case point data in Weihe Basin from 2005 to 2020. MaxEnt models were constructed to explore the main influencing factors of HFRS epidemic based on HFRS data, natural environment factors and socioeconomic factors.
    Results: Results showed that the HFRS epidemics in Weihe Basin were temporally divided into three periods (the relatively stable period, the rapid rising period, and the fluctuating rising period) and were spatially featured by relatively concentrated in the plains alongside the Weihe River. Landscape played controlling effect in this area while land use, vegetation and population in the area interacted with each other and drove the change of HFRS epidemic. The potential high-risk area for HFRS epidemic was 419 km2, where the HFRS case density reached 12.48 cases/km2, especially in the northern plains of Xi'an City.
    Conclusion: We suggested that the temporal and spatial variations in the HFRS epidemics, as well as their dominant influencing factors should be adequately considered for making and/or adjusting the targeted prevention and control strategies on this disease in Weihe Basin.
    MeSH term(s) Animals ; Hemorrhagic Fever with Renal Syndrome/epidemiology ; Incidence ; Epidemics ; China/epidemiology ; Rivers
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0011245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Triple-emission nitrogen and boron co-doped carbon quantum dots from lignin: Highly fluorescent sensing platform for detection of hexavalent chromium ions

    Zhu, Lingli / Shen, Dekui / Hong Luo, Kai

    Journal of colloid and interface science. 2022 July, v. 617

    2022  

    Abstract: Considering that hexavalent chromium ions (Cr⁶⁺) with high toxicity poses a huge threat to human health and the ecological environment, constructing a rapid and accurate sensing platform is of great significance in detecting the toxic substance. The ... ...

    Abstract Considering that hexavalent chromium ions (Cr⁶⁺) with high toxicity poses a huge threat to human health and the ecological environment, constructing a rapid and accurate sensing platform is of great significance in detecting the toxic substance. The novel nitrogen and boron co-doped carbon quantum dots (N, B-CQDs) from lignin are synthesized as fluorescent sensors for the detection of Cr⁶⁺. The synthetic processes involve the acid hydrolysis step followed by the hydrothermal treatment step. Lignin is firstly depolymerized by cleaving ether bonds in the acidolysis, and N, B-CQDs are consequently formed by the aromatic re-fusion of lignin nanoparticles in the hydrothermal process. The lignin-derived N, B-CQDs show triple emission of purple, blue and green fluorescence under the excitation of 300, 330, and 490 nm, respectively. The triple-emission N, B-CQDs are applied for the triple-channel detection of Cr⁶⁺, which exhibit highly sensitive and selective fluorescence quenching for Cr⁶⁺ with good linearity (R² ≤ 0.996) and very low limit of detection as 0.054, 0.049, and 0.077 μM under the excitation of 300, 330 and 490 nm, respectively. The utilization of renewable lignin as CQDs-based fluorescent sensors opens a new avenue for the rapid and accurate detection of Cr⁶⁺ through a multichannel sensing platform.
    Keywords acid hydrolysis ; acidolysis ; boron ; chromium ; detection limit ; fluorescence ; hot water treatment ; human health ; lignin ; nitrogen ; toxicity
    Language English
    Dates of publication 2022-07
    Size p. 557-567.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.03.039
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Technique failure in peritoneal dialysis-related peritonitis: risk factors and patient survival.

    Yu, Jin / Zhu, Lingli / Ni, Jun / Tong, Mengli / Wang, Hua

    Renal failure

    2023  Volume 45, Issue 1, Page(s) 2205536

    Abstract: Objective: This study aimed to investigate the association between patient clinical characteristics and technique failure in peritoneal dialysis-related peritonitis (PDRP). The effect of peritonitis-associated technique failure on patient survival was ... ...

    Abstract Objective: This study aimed to investigate the association between patient clinical characteristics and technique failure in peritoneal dialysis-related peritonitis (PDRP). The effect of peritonitis-associated technique failure on patient survival was also assessed.
    Methods: Patients diagnosed with PDRP from January 1, 2010 to June 30, 2022 were retrospectively reviewed and analyzed. Relevant demographic, biochemical, and clinical data were collected. Univariate and multivariate logistic regression analyses were used to determine the predictors of peritonitis-associated technique failure in PD. Patients were divided into technique failure (F group) and nontechnique failure (NF group) groups. Patients were followed until death or until the date of Oct 1, 2022. Kaplan-Meier survival curves and landmark analysis were used to assess the survival of the PDRP cohort. Cox regression models were used to assess the association between potential risk factors and mortality.
    Results: A total of 376 patients with 648 cases of PDRP were included in this study. Multivariate logistic regression analysis demonstrated that peritoneal dialysis (PD) duration (OR = 1.12 [1.03, 1.21],
    Conclusions: Dialysate WBC count on Day 3, PD duration, NLR, and LDH were independent risk factors for technique failure, whereas HDL was a protective factor. Peritonitis-associated technique failure had a higher risk of mortality and adverse effects on postperitonitis survival.
    MeSH term(s) Humans ; Retrospective Studies ; Peritoneal Dialysis/adverse effects ; Dialysis Solutions ; Risk Factors ; Peritonitis/etiology ; Peritonitis/diagnosis ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy
    Chemical Substances Dialysis Solutions
    Language English
    Publishing date 2023-04-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 632949-4
    ISSN 1525-6049 ; 0886-022X
    ISSN (online) 1525-6049
    ISSN 0886-022X
    DOI 10.1080/0886022X.2023.2205536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Facile Synthesis of Multi-Emission Nitrogen/Boron Co-Doped Carbon Dots from Lignin for Anti-Counterfeiting Printing.

    Gu, Xuexin / Zhu, Lingli / Shen, Dekui / Li, Chong

    Polymers

    2022  Volume 14, Issue 14

    Abstract: The transformation of lignin with natural aromatic structure into value-added carbon dots (CDs) achieves a win-win situation for low-cost production of novel nanomaterials and reasonable disposal of biomass waste. However, it remains challenging to ... ...

    Abstract The transformation of lignin with natural aromatic structure into value-added carbon dots (CDs) achieves a win-win situation for low-cost production of novel nanomaterials and reasonable disposal of biomass waste. However, it remains challenging to produce multi-emission CDs from biomass for advanced applications. Herein, a green and facile approach to preparing multi-emission CDs from alkali lignin via N and B co-doping is developed. The obtained N and B co-doped CDs (NB-CDs) show multi-emission fluorescence centers at 346, 428 and 514 nm under different excitations. As the doping amount of N and B increases, the fluorescence emission band gradually shifts to 428 and 514 nm, while that at 346 nm decreases. The fluorescence mechanism is explored through the research of the structure, composition and optical performance of NB-CDs in combination with density functional theory (DFT) calculations. It demonstrates that the effect of doping with B-containing functional groups on the fluorescence emission behavior is multivariate, which may be the crucial contribution to the unique multi-emission fluorescence of CDs. The multi-emission NB-CDs with prominent stability are applied for multilevel anti-counterfeiting printing. It provides a promising direction for the sustainable and advanced application of biomass-derived CDs, and the theoretical results highlight a new insight into the deep understanding of the multi-emission fluorescence mechanism.
    Language English
    Publishing date 2022-07-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14142779
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Triple-emission nitrogen and boron co-doped carbon quantum dots from lignin: Highly fluorescent sensing platform for detection of hexavalent chromium ions.

    Zhu, Lingli / Shen, Dekui / Hong Luo, Kai

    Journal of colloid and interface science

    2022  Volume 617, Page(s) 557–567

    Abstract: Considering that hexavalent chromium ions ( ... ...

    Abstract Considering that hexavalent chromium ions (Cr
    MeSH term(s) Boron ; Carbon/chemistry ; Chromium ; Fluorescent Dyes ; Humans ; Ions ; Lignin/chemistry ; Nitrogen/chemistry ; Quantum Dots
    Chemical Substances Fluorescent Dyes ; Ions ; Chromium (0R0008Q3JB) ; chromium hexavalent ion (18540-29-9) ; Carbon (7440-44-0) ; Lignin (9005-53-2) ; Nitrogen (N762921K75) ; Boron (N9E3X5056Q)
    Language English
    Publishing date 2022-03-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.03.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Crosslinking Improve Demineralized Dentin Performance and Synergistically Promote Biomimetic Mineralization by CaP_PILP.

    Tang, Lin / Zhu, Lingli / Liu, Yuhua / Zhang, Yi / Li, Bowen / Wang, Mei

    ACS omega

    2023  Volume 8, Issue 16, Page(s) 14410–14419

    Abstract: Objective: to explore the effects of optimal crosslinking (chemical treatment) on demineralized dentin matrix and the possible synergism with calcium phosphate polymer-induced liquid precursor (CaP-PILP) bionic remineralization (physical treatment), and ...

    Abstract Objective: to explore the effects of optimal crosslinking (chemical treatment) on demineralized dentin matrix and the possible synergism with calcium phosphate polymer-induced liquid precursor (CaP-PILP) bionic remineralization (physical treatment), and offer benefit to the clinic of resin-dentin bonding and dentin hypersensitivity.
    Methods: demineralized dentin was treated with glutaraldehyde (GA), carbodiimide (EDC), and procyanidin (PA) for crosslinking, followed by CaP-PILP biomimetic remineralization. The morphology, surface mechanical and physio-chemical properties, and enzymatic resistance were evaluated regardless of the modification.
    Results: the collagen fibers appeared morphologically complete with higher surface microhardness and characteristic peaks of amide I-III bands were visible after GA, PA, and EDC crosslinking. Collagen collapse and dissolution were seen in untreated demineralized dentin with enzyme attack, while the collagen fiber structure remained intact in GA- and PA-treated specimens. The lamellar mineral phase was visible at 2 days and the dentin tubules were almost completely enclosed at 4-6 days after PA crosslinking and mineralization. However, demineralized collagen fibers and open tubules were still visible between the dentinal tubules on day 8 in the control group.
    Conclusion: the structure integrity, enzyme resistance, and mechanical properties of the collagen fiber network could be significantly preserved by GA and PA crosslinking than EDC and no treatment. While, strongest synergistic effects were observed in PA on bionic remineralization by CaP-PILP, and further significantly improve the quality and shorten the duration of mineralization. These findings would be beneficial for dental clinical practice of resin-dentin bonding and dentin hypersensitivity.
    Language English
    Publishing date 2023-04-11
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c07825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Effects of varenicline on the serum levels of olanzapine in male patients with Schizophrenia: a randomized controlled trial.

    Deng, Mengling / Yang, Zhi / Ni, Yanfei / Zhu, Lingli / Xu, Jiating / Zheng, Lifeng / Zhou, Bo

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1142419

    Abstract: Background: Smoking in patients with Schizophrenia is more common than in the general population. Varenicline, a partial agonist at α4β2 nicotinic acetylcholine receptors, is an effective smoking cessation pharmacotherapy in patients with Schizophrenia. ...

    Abstract Background: Smoking in patients with Schizophrenia is more common than in the general population. Varenicline, a partial agonist at α4β2 nicotinic acetylcholine receptors, is an effective smoking cessation pharmacotherapy in patients with Schizophrenia. However, its effects on the serum levels of antipsychotics in Schizophrenia are understudied. This study investigated the impact of smoking cessation with varenicline on the serum concentration of olanzapine in patients with Schizophrenia.
    Methods: Adult smokers with Schizophrenia were enrolled in a 12-week course of varenicline and placebo for smoking cessation. The serum concentration of olanzapine was measured at baseline and weeks 1, 2, 4, 8, and 12. Data were analyzed with the generalized additive mixed model.
    Results: During the 12-week study, the results indicated that olanzapine concentrations increased nonlinearly in the varenicline and placebo groups. Threshold effect analysis suggested that the olanzapine concentrations increased over time until the turning point (week 4). However, there was no significant difference between the two treatment groups.
    Conclusion: Varenicline showed safety and efficacy in smoking cessation in people with Schizophrenia.
    Language English
    Publishing date 2023-05-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1142419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Barriers and facilitators of adherence to awake prone positioning: a qualitative study using the COM-B model.

    Zhu, Lingli / Ni, Zijun / Zhang, Yuping / Zhan, Yang / Lan, Meijuan / Zhao, Ruiyi

    BMC pulmonary medicine

    2023  Volume 23, Issue 1, Page(s) 267

    Abstract: Background: Awake prone positioning (APP) is a recommended therapy for non-intubated ARDS patients, but adherence can be challenging. Understanding the barriers and facilitators of adherence to APP is essential to increase the adherence of therapy and ... ...

    Abstract Background: Awake prone positioning (APP) is a recommended therapy for non-intubated ARDS patients, but adherence can be challenging. Understanding the barriers and facilitators of adherence to APP is essential to increase the adherence of therapy and improve patient outcomes. The objective of this study was to explore the barriers and facilitators of adherence to awake prone ventilation using a qualitative approach and the Capability, Opportunity, Motivation-Behavior (COM-B) model.
    Methods: Semi-structured, in-depth interviews were conducted with patients involved in awake prone ventilation. Data were analyzed using an adapted inductive thematical approach and mapped onto the COM-B model to identify barriers and facilitators to adherence of APP.
    Results: Nineteen patients were interviewed (aged 55-92 years). Fifteen themes were identified and mapped directly on to the six COM-B constructs, with "physical challenges" related to physical capability being the primary barrier. These COM-B sub-items reflected five other barriers, including low self-efficacy(M), treatment environment(O), availability of time(O), misconceptions about the treatment(C), and insufficient knowledge(C). Key facilitators in adhering to APP were ability to identify and overcome obstacles(C), availability and affordability of treatment(O), family influences(O), beliefs and trust in treatment(M), fear about the disease(M), and perceived benefits(M). In addition, three factors played the role of both facilitator and barrier, such as media influences(O), healthcare influences(O), and behavioral habits(M).
    Conclusion: The COM-B model was proved to be a useful framework for identifying the barriers and facilitators of adherence to awake prone ventilation. The findings suggest that adherence behavior is a dynamic and balanced process and interventions aimed at improving adherence to APP should address the barriers related to capability, opportunity, and motivation. Healthcare providers should focus on providing proper guidance and training, creating a comfortable environment, and offering social support to improve patients' capability and opportunity. Additionally, promoting patients' positive beliefs and attitudes towards the treatment and addressing misconceptions and fears can further enhance patients' motivation to adhere to the treatment plan.
    MeSH term(s) Humans ; Wakefulness ; Motivation ; Prone Position ; Qualitative Research ; Health Personnel
    Language English
    Publishing date 2023-07-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-023-02561-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comparison of Pairwise Venous and Fingertip Plasma Using Quantitative Proteomics Based on Data-Independent Acquisition.

    Xu, Ganfei / Lv, Jiacheng / Huang, Mingjing / Zhu, Lingli / Tan, Subei / Ding, Chen

    Journal of proteome research

    2023  Volume 22, Issue 4, Page(s) 1347–1358

    Abstract: Blood contains a great deal of health-related information and can be used to monitor human health status. Clinically, venous or fingertip blood is usually used for blood tests. However, the clinical application settings of the two sources of blood are ... ...

    Abstract Blood contains a great deal of health-related information and can be used to monitor human health status. Clinically, venous or fingertip blood is usually used for blood tests. However, the clinical application settings of the two sources of blood are unclear. In this study, the proteomes of pairwise venous plasma (VP) and fingertip plasma (FP) were analyzed, and the levels of 3797 proteins were compared between VP and FP. The Spearman's correlation coefficient for the relationship between protein levels of VP and FP ranges from 0.64 to 0.78 (
    MeSH term(s) Humans ; Proteome/genetics ; Proteome/metabolism ; Proteomics ; Karyopherins
    Chemical Substances Proteome ; XPO5 protein, human ; Karyopherins
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2078618-9
    ISSN 1535-3907 ; 1535-3893
    ISSN (online) 1535-3907
    ISSN 1535-3893
    DOI 10.1021/acs.jproteome.3c00081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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